Efficacy and safety of tenofovir and entecavir in patients with chronic hepatitis B-related cirrhosis: a systematic review and meta-analysis by Lu Cao, Li Li, Lixing Yang, Nan Zhou, Yu Zhang

“…Tenofovir did not significantly cause renal dysfunction, but instead improved estimated glomerular filtration rate levels compared with entecavir. Randomized controlled trials with larger sample size are still needed for validation.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024588432.…”
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Psilocybin-assisted massed cognitive processing therapy for chronic posttraumatic stress disorder: Protocol for an open-label pilot feasibility trial. by Shakila Meshkat, Richard J Zeifman, Kathleen Stewart, Reinhard Janssen-Aguilar, Wendy Lou, Rakesh Jetly, Candice M Monson, Venkat Bhat

“…The findings will guide the design of a multi-site, large-scale randomized control trial to more rigorously assess the efficacy of this intervention. …”
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Rasagiline as Adjunct to Levodopa for Treatment of Parkinson’s Disease: A Systematic Review and Meta-Analysis by Osamu Kano, Hiroshi Tsuda, Ayako Hayashi, Masaki Arai

“…A systematic literature search was conducted (January 18-19, 2021) using PubMed, Cochrane Library, EMBASE, Web of Science, and Google Scholar to identify randomized controlled trials comparing rasagiline/levodopa versus placebo/levodopa in patients with Parkinson’s disease experiencing motor fluctuations. …”
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Efficacy of Tunnel Technique (TUN) versus Coronally Advanced Flap (CAF) in the Management of Multiple Gingival Recession Defects: A Meta-Analysis by Frank Mayta-Tovalino, Joshuan J. Barboza, Vinay Pasupuleti, Adrian V. Hernandez

“…Five databases were searched until September 2021 for randomized controlled trials (RCTs) assessing TUN vs. CAF; grafts of interest were acellular dermal matrix (ADM) and connective tissue graft (CTG). …”
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Nutritional Counseling During Chemotherapy Treatment: A Systematic Review of Feasibility, Safety, and Efficacy by Shalet James, Alexie Oppermann, Kaitlin M. Schotz, Mackenzie M. Minotti, Gautam G. Rao, Ian R. Kleckner, Brenton J. Baguley, Amber S. Kleckner

“…Among 44 publications, 39 studies recruited 98 ± 80 participants (range 15–360); 38/39 (97%) were randomized controlled trials. One-third (31%) were among patients with breast cancer. …”
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Leukodepleted Packed Red Blood Cells Transfusion in Patients Undergoing Major Cardiovascular Surgical Procedure: Systematic Review and Meta-Analysis by Daniel Simancas-Racines, Ingrid Arevalo-Rodriguez, Gerard Urrutia, Diana Buitrago-Garcia, Solange Núñez-González, María José Martínez-Zapata, Eva Madrid, Xavier Bonfill, Ricardo Hidalgo-Ottolenghi

“…We searched randomized controlled trials (RCT), enrolling patients undergoing a major cardiovascular surgical procedure and transfused with LD-PRBC. …”
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Advancements related to probiotics for preventing and treating recurrent respiratory tract infections in children by Yali Zhang, Yali Zhang, Yingying Xu, Yingying Xu, Ling Hu, Ling Hu, Xiaomei Wang

“…In conclusion, we propose future research directions including conducting more high-quality randomized controlled trials to optimize application strategies for probiotics alongside other treatments while considering variations based on age and health conditions among pediatric populations. …”
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Testing Multi-Theory Model (MTM) in Predicting Physical Activity Behavior Among Upper Elementary School Children in Northern India by Poonam KHANNA, Tejinder Pal SINGH, Tarundeep SINGH, Rekha KAUSHIK, Manoj SHARMA

“…More empirical work needs to be undertaken in India, using randomized controlled trials that operationalize expanded form of this model.…”
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Right Ventricular Remodeling and Dysfunction in Obstructive Sleep Apnea: A Systematic Review of the Literature and Meta-Analysis by Abdirashit Maripov, Argen Mamazhakypov, Meerim Sartmyrzaeva, Almaz Akunov, Kubatbek Muratali uulu, Melis Duishobaev, Meerim Cholponbaeva, Akylbek Sydykov, Akpay Sarybaev

“…However, large randomized controlled trials evaluating the impact of OSA on the right ventricle are lacking. …”
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The Role of Virtual Reality in Postural Rehabilitation for Patients with Parkinson’s Disease: A Scoping Review by Francesco Agostini, Marco Conti, Giovanni Morone, Giovanni Iudicelli, Andrea Fisicaro, Alessio Savina, Massimiliano Mangone, Marco Paoloni

“…A scientific literature search was performed using the following databases: PubMed, PEDro, Cochrane, and Google Scholar, focusing on randomized controlled trials (RCTs) published in English. Our selection criteria included studies that compared VR-based rehabilitation to traditional methods regarding posture-related outcomes. …”
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Grazoprevir and Elbasvir in Patients with Genotype 1 Hepatitis C Virus Infection: A Comprehensive Efficacy and Safety Analysis by Yinan Yao, Ming Yue, Jie Wang, Hongbo Chen, Mei Liu, Feng Zang, Jun Li, Yun Zhang, Peng Huang, Rongbin Yu

“…A comprehensive analysis was performed to evaluate the efficacy and safety of the grazoprevir combined with elbasvir, with or without ribavirin (RBV), in 777 treatment-naive and treatment-experienced patients with HCV genotype 1 infection from 3 randomized controlled trials (RCTs). Method. We collected data from the following trials: C-WORTHY (NCT01717326), C-SALVAGE (NCT02105454), and C-EDGE (NCT02105467). …”
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A Systematic Review and Meta-Analysis of Mapping Biopsy for Primary Extramammary Paget’s Disease in Reducing Recurrence Following Surgical Excision by Thirrisha Murugan, Louis Choon Kit Wong, MD, Xing-Yi Sarah Ong, MD, Sze Huey Tan, PhD, Joey Wee-Shan Tan, MSc, Ying Liu, PhD, Nicholas B. Shannon, PhD, MD, Jianbang Chiang, MBBS, MRCP, MMed, Eileen Poon, MBBS, MRCP, MMED, Jason Yongsheng Chan, MBBS, MRCP, MMed, FAMS, PhD, Valerie Shiwen Yang, MB BChir, PhD, MRCP, FAMS, Nagavalli Somasundaram, MBBS, MRCP, MMED, Mohamad Farid, MBBS, MRCP, MMed, Ru Xin Wong, MBBS, FRCR, Wen Long Nei, MBBS, FRCR, Jin Wei Kwek, MBBS, FRCR, FAMS, Choon Hua Thng, MBBS, FRCR, FAMS, Tiffany Hennedige, MBBS, FRCR, MMed, MCI, Po Yin Tang, BMEDSc, MBBS, FRCPath, FRCAPA, Sathiyamoorthy Selvarajan, MBBS, PGDCP, FRCPath, MCS, FAMS, Kae Jack Tay, MBBS, MRCS, MMed, MCI, FAMS, Mohamed Rezal Abdul, MB, BCh, BAO, LRCP&SI, MSurg, Jolene Si Min Wong, MBBS, MMed, FRCS, Chin Jin Seo, MB, BCh, BAO, MMed, FRCS, Khee Chee Soo, MBBS, MD, FRACS, FACS, Claramae Shulyn Chia, MBBS, MMed, FRCS, Chin-Ann Johnny Ong, MBBS, MMed, FRCS, PhD

“…Mapping biopsies are able to improve EMPD surgical excision outcomes but given the rarity of the disease and heterogeneity of mapping biopsy procedures, further confirmation with randomized controlled trials or a larger patient pool is necessary.…”
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Association of Inflammatory Profile During Ex Vivo Lung Perfusion With High-Grade Primary Graft Dysfunction: A Systematic Review and Meta-Analysis by Andrea Costamagna, Eleonora Balzani, Matteo Marro, Erika Simonato, Alessandro Burello, Mauro Rinaldi, Luca Brazzi, Massimo Boffini, Vito Fanelli

“…This systematic-review and meta-analysis of non-randomized controlled trials on patients undergoing Ltx with reconditioned lungs via EVLP, aims to assess the association between the levels of proinflammatory biomarkers during EVLP and PGD3 development within the firsts 72 h post-Ltx. …”
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Optimal Timing and Treatment Modalities of Arytenoid Dislocation and Subluxation: A Meta-Analysis by Andrea Frosolini, Valeria Caragli, Giulio Badin, Leonardo Franz, Patrizia Bartolotta, Andrea Lovato, Luca Vedovelli, Elisabetta Genovese, Cosimo de Filippis, Gino Marioni

“…<i>Conclusions</i>: The absence of randomized controlled trials and the overall moderate-to-low quality of the studies highlighted the importance of the finding’s careful interpretation. …”
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Chatting your way to quitting: A longitudinal exploration of smokers' interaction with a cessation chatbot by Linwei He, Erkan Basar, Reinout W. Wiers, Marjolijn L. Antheunis, Emiel Krahmer

“…Future research should further validate these findings with randomized controlled trials. Additional efforts should focus on monitoring and maintaining user experience in the long term to enhance effectiveness.…”
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From chaos to order: optimizing fecal microbiota transplantation for enhanced immune checkpoint inhibitors efficacy by Anqi Lin, Aimin Jiang, Lihaoyun Huang, Yu Li, Chunyanx Zhang, Lingxuan Zhu, Weiming Mou, Zaoqu Liu, Jian Zhang, Quan Cheng, Ting Wei, Peng Luo

“…We outline critical research directions, encompassing the need for large-scale, multi-center randomized controlled trials, in-depth microbial ecology studies, and the integration of multi-omics approaches with artificial intelligence. …”
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A scoping review examining the relationship between green tea and skin cancers by Ram Lakhan, Louisa Summers, Olugbemiga Ekundayo, Jedidiah Radosevich, Sierra Turner, Sangyal Dorjee, Vinayak K. Nahar, Manoj Sharma

“…Large scale randomized controlled trials on the efficacy of green tea and its extracts are required.…”

Comparative efficacy of topical commercial Chinese polyherbal preparation for vulvovaginal candidiasis: a network meta-analysis by Lizheng Wu, Shangwen Jing, Na Li, Dandan Cao, Fangli Pei, Yantong Luo, Xiaoxin Chen, Yingjie Huang, Cheng Zeng

“…ObjectiveTo systematically evaluate the differences in the efficacy of commonly used topical commercial Chinese polyherbal preparations (CCPPs) for vulvovaginal candidiasis (VVC), and to provide evidence-based reference for clinical drug regimens.MethodsComputer searched major Chinese and English literature databases, and collected randomized controlled trials (RCTs) of external use of CCPPs combined with conventional treatment (CT, test group) versus CT alone (control group) in patients with VVC. …”
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Effects of an intervention combining physical activity and components of Amygdala and Insula Retraining (AIR) on sleep and working memory among older male adults by Monireh Asadi Ghaleni, Forouzan Fattahi Masrour, Narjes Saryar, Alexandra J. Bratty, Ebrahim Norouzi, Matheus Santos de Sousa Fernandes, Georgian Badicu

“…The effectiveness of Physical Activity plus selected components of Amygdala and Insula Retraining (PAAIR) was tested to improve sleep quality, depression, working memory, and emotion regulation among older males.MethodsThis was a parallel, randomized control trial. The study was conducted in-person among 40 older Iranian men (Mage: 65.78, SD = 2.41). …”
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Low-Frequency Repetitive Transcranial Magnetic Stimulation for Stroke-Induced Upper Limb Motor Deficit: A Meta-Analysis by Lan Zhang, Guoqiang Xing, Shiquan Shuai, Zhiwei Guo, Huaping Chen, Morgan A. McClure, Xiaojuan Chen, Qiwen Mu

“…Databases of PubMed, Medline, ScienceDirect, Cochrane, and Embase were searched for randomized controlled trials published before Jun 31, 2017. The effect size was evaluated by using the standardized mean difference (SMD) and a 95% confidence interval (CI). …”
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