Sequential use of low-load-blood-flow-restricted vs. high-load resistance training on neuromuscular activation, hypertrophy and neuromuscular performance by Romina Ledergerber, Paul Ritsche, Eric Lichtenstein, Martin Keller

“…Methods In this 10-week randomized controlled trial, 37 healthy male and female adults (35-60 years) completed progressive resistance training for knee extensors either 8 weeks with low-load BFRT followed by 2 weeks of HLT, or exclusively HLT. …”
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The FIT FIRST 10 dose-response study: evaluation of implementation outcomes by Sofie Koch, Sofie Koch, Caroline Eckert, Nikos Ntoumanis, Nikos Ntoumanis, Nikos Ntoumanis, Cecilie Thøgersen-Ntoumani, Cecilie Thøgersen-Ntoumani, Cecilie Thøgersen-Ntoumani, Chiara Cimenti, Chiara Cimenti, Malte Nejst Larsen, Peter Krustrup, Peter Krustrup, Lars Breum Skov Christiansen, Lars Breum Skov Christiansen

“…This study evaluates the implementation of the FF10 program for 2nd and 3rd graders.Materials and methodsThe FF10 program was implemented in a 20-week cluster randomized controlled trial across 27 schools. Schools were assigned to a control arm or intervention arms receiving either 3 (full dose) or 1.5 (half dose) FF10 40-min lessons weekly. …”
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Brief Mindfulness-Based Cognitive Therapy in Women With Myocardial Infarction by Tanya M. Spruill, PhD, Chorong Park, PhD, RN, Jolaade Kalinowski, EdD, Milla E. Arabadjian, PhD, RN, Yuhe Xia, MSc, Amanda J. Shallcross, ND, MPH, Pallavi Visvanathan, PhD, Nathaniel R. Smilowitz, MD, MS, Anaïs Hausvater, MD, Sripal Bangalore, MD, MHA, Hua Zhong, PhD, Ki Park, MD, Puja K. Mehta, MD, Dwithiya K. Thomas, MD, Jeffrey Trost, MD, Kevin R. Bainey, MD, Bobak Heydari, MD, Janet Wei, MD, Victoria Vaughan Dickson, PhD, RN, Gbenga Ogedegbe, MD, MPH, Jeffrey S. Berger, MD, MS, Judith S. Hochman, MD, Harmony R. Reynolds, MD

“…Objectives: This randomized controlled trial tested effects of a mindfulness-based intervention on stress levels among women with MI. …”
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Phase II, single-arm trial of preoperative short-course radiotherapy followed by chemotherapy and camrelizumab in locally advanced rectal cancer by Jun Fan, Jing Wang, Tao Zhang, Xin Li, Lan Zhang, Zheng Wang, Tao Liu, Gang Li, Peng Zhang, Chi Ma, Ming Cai, Gang Wu, Zhenyu Lin, Kailin Cai, Xiu Nie, Junli Liu, Hongli Liu, Weikang Zhang, Jingbo Gao, Chuanqing Wu, Linfang Wang, Zhiguo Hou, Kunyu Yang, Kaixiong Tao

“…Biomarker analysis showed patients without FGFR1–3 deletions had a better tendency for pCR.Conclusions SCRT combined with subsequent CAPOX plus camrelizumab followed by delayed surgery showed a favorable pCR rate with good tolerance in patients with LARC, especially in the proficient MMR setting. A randomized controlled trial is ongoing to confirm these results.Trial registration number ClinicalTrials.gov identifier: NCT04231552.…”
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Excess costs of post-traumatic stress disorder related to child maltreatment in Germany by Thomas Grochtdreis, Hans-Helmut König, Falk Leichsenring, Manfred E. Beutel, Lila Feix, Harald Gündel, Andrea Hermann, Melissa Hitzler, Christine Knaevelsrud, Iris-Tatjana Kolassa, Johannes Kruse, Helen Niemeyer, Fatima Nöske, Simone Salzer, Karoline Sophie Sauer, Patrick Schuster, Christiane Steinert, Kerstin Weidner, Jörn von Wietersheim, Jürgen Hoyer, Judith Dams

“…Methods Baseline data from a multi-center randomized controlled trial on individuals with PTSD-CM (n = 361) were combined with data from individuals without PTSD (n = 4760). …”
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Release velocity ImprovemenT with a new Metronome guIding chest COmpressions: The RITMICO simulation study by Maria Luce Caputo, Giuliana Monachino, Ruggero Cresta, Alessia Currao, Enrico Baldi, Simone Savastano, Andrea Cortegiani, Mariachiara Ippolito, Sara Accetta, Alessandra Gargano, Camilla Metelmann, Bibiana Metelmann, Carlos Ramon Hölzing, Julian Ganter, Michael Patrick Müller, Claudio Benvenuti, Stefania Tomola, Pierangelo Pinetti, Pier Luigi Ingrassia, Francesca Dalia Faraci, Angelo Auricchio

“…We performed a multicenter non-blinded, randomized, controlled trial including volunteers with different levels of CPR expertise. …”
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“Holding on to Hope”: follow up qualitative findings of a tobacco treatment intervention for people experiencing mental health conditions by Tessa-May Zirnsak, Kristen McCarter, Melissa L. McKinlay, Ashleigh Guillaumier, Nadine Cocks, Catherine Brasier, Laura Hayes, Amanda L. Baker, Donita E. Baird, Billie Bonevski, Ron Borland, Ron Borland, David Castle, Erin Forbes, Peter J. Kelly, Catherine Segan, Catherine Segan, Rohan Sweeney, Alyna Turner, Alyna Turner, Jill M. Williams, Lisa Brophy, Lisa Brophy

“…The Quitlink study was a randomized controlled trial combining a tailored 8-week Quitline intervention delivered by dedicated Quitline counsellors plus combination nicotine replacement therapy for people who experience SMI. …”
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Effects of a liquefied petroleum gas stove and fuel intervention on head circumference and length at birth: A multi-country household air pollution intervention network (HAPIN) tri... by Hina Raheel, Sheela Sinharoy, Anaité Diaz-Artiga, Sarada S. Garg, Ajay Pillarisetti, Kalpana Balakrishnan, Marilu Chiang, Amy Lovvorn, Miles Kirby, Usha Ramakrishnan, Shirin Jabbarzadeh, Alexie Mukeshimana, Michael Johnson, John P. McCracken, Luke P. Naeher, Ghislaine Rosa, Jiantong Wang, Joshua Rosenthal, William Checkley, Thomas F. Clasen, Jennifer L. Peel, Lisa M. Thompson

“…Methods: The Household Air Pollution Intervention Network (HAPIN) trial was an open label multi-country-randomized controlled trial, with 3200 pregnant women aged 18–34 years (9–19 weeks of gestation) randomly assigned in a 1:1 ratio to receive liquefied petroleum gas (LPG) stove intervention compared to women continuing to cook with solid fuels for 18 months. …”
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Opioids in Chronic Noncancer Pain: More Faces from the Crowd by C Peter N Watson

“…There are several randomized controlled trials, mostly in neuropathic pain, reporting efficacy and safety in the short term, but more long-term data are needed. …”
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Should We Test for Helicobacter Pylori before Treating Gastroesophageal Reflux Disease? by Paul Moayyedi

“…There are no data from children but inferences from randomized controlled trials in adults suggest this effect is likely to be modest and of uncertain clinical significance. …”
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A systematic review and meta-analysis of neuromuscular electrical stimulation post-botulinum toxin injection in children with cerebral palsy by Fu-An Yang, Jie-Ren Mi Le, Chia-Hsiang Lu, Chao-Chun Huang, Hung-Chou Chen

“…Two independent reviewers extracted data, and risks of bias were assessed using the PEDro scale for randomized controlled trials. We included 5 randomized controlled trials in this meta-analysis. …”
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A Comparison of the Morbidities Associated with Different Early Treatments in Tubo-Ovarian Abscess Patients by Sumanta Saha, Sujata Saha

“…RESULTS: From 164 studies, five eligible papers (four non-randomized studies and one randomized controlled trials) were reviewed. These studies sourced data from 609 tubo-ovarian abscess patients. …”
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Trends in Inflammatory Bowel Disease Therapy: A Meta-Analytic Approach by Gregory W Whiting, Joseph Lau, Bruce Kupelnick, Thomas C Chalmers

“…OBJECTIVE: To illustrate the current meta-analytic approach to extracting clinically useful information from the glut of randomized controlled trials (RCTs) of the treatment of acute attacks of Crohn's disease.…”
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The Long-Term Safety and Efficacy of Opioids: A Survey of 84 Selected Patients with Intractable Chronic Noncancer Pain by C Peter N Watson, Judy Watt-Watson, Mary Chipman

“…Despite a number of randomized controlled trials showing efficacy and safety in the short term, long-term data are limited.…”
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Endoscopic Band Ligation Versus Pharmacological Therapy for Variceal Bleeding in Cirrhosis: A Meta-Analysis by Lan Li, Chaohui Yu, Youming Li

“…OBJECTIVE: To conduct a meta-analysis of published, full-length, randomized controlled trials evaluating the efficacy of endoscopic band ligation (EBL) versus pharmacological therapy for the primary and secondary prophylaxis of variceal hemorrhage in patients with cirrhosis.…”
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How effective is the addition of specific exercise therapy for patients after anterior cruciate ligament surgery? A systematic review and meta-analysis by Hao Zhou, Jia Qian, Yu-Mei Xing, Long Cui, Yi-Feng Bu

“…Several rehabilitation methods have been used for patients after ACL surgery.ObjectiveThis study aimed to assess the overall efficacy of exercise therapy in improving outcomes for patients following ACL surgery using a systematic review and meta-analysis of randomized controlled trials (RCTs).Data sourcesPubMed, Web of Science, Embase, and the Cochrane Library were searched for randomized controlled trials published from 1 January 2000 to 30 August 2024. …”
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Patent Foramen Ovale Closure for Treating Migraine: A Meta-Analysis by Yu Zhang, Haijiao Wang, Ling Liu

“…In total, three randomized controlled trials, one pooled study, and eight retrospective case series including 1,165 participants were included in the meta-analysis. …”
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Effects of tranquilization therapy in elderly patients suffering from chronic non-communicable diseases: A meta-analysis by Li Jing, Li Jing, Cui Yulan, Li Honggeng, Hou Xiaoxuan, Zhao Fang, Zhao Qing, Zhao Junlan, Lin Pengchao

“…This meta-analysis includes 16 randomized control trials spanning the years 2000 to 2022, using the data from 2224 patients. …”
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Febuxostat Improves Uric Acid Levels and Renal Function in Patients with Chronic Kidney Disease and Hyperuricemia: A Meta-Analysis by Yanqun Zheng, Jia Sun

“…Eight databases included were searched for clinical randomized controlled trials. Meanwhile, the confidence interval (CI) of either relative risk or mean difference was set to 95%. …”
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Treatment of Neuropathic Pain: Focus on Antidepressants, Opioids and Gabapentin by C Peter N Watson, Judith H Watt-Watson

“…BACKGROUND: The treatment of neuropathic pain continues to be difficult. Randomized, controlled trials (RCTs) provide some evidence to guide therapy. …”
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