Enhancing foster care relationships through attachment-based intervention: the safe families study protocol, a randomized controlled trial of the circle of security parenting program® by Mathieu Pereira, Lauriane Sedes, Emilie Gadéa, Rebecca Shankland

“…Methods This study protocol follows a mixed-methods randomized controlled trial evaluating the effectiveness of the COS-P program for foster carers in France. …”
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Angiotensin receptor neprilysin inhibition versus individualized RAAS blockade: design and rationale of the PARALLAX trial by Rolf Wachter, Sanjiv J. Shah, Martin R. Cowie, Peter Szecsödy, Victor Shi, Ghionul Ibram, Ziqiang Zhao, Jianjian Gong, Sven Klebs, Burkert Pieske

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Evaluating the efficacy of multi-incision and tube-dragging therapy combined with laser closure for high horseshoe-shaped anal fistula: Protocol of a prospective, randomized, controlled trial. by Min Yang, Zubing Mei, Qingming Wang, Ye Han, De Zheng

“…Due to the current scarcity of rigorous evidence evaluating this approach, it is essential to perform a well-designed randomized controlled trial to compare the effectiveness of this new method with incision and thread-drawing therapy.…”
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Efficacy and safety of PD-1/PD-L1 inhibitors in advanced or recurrent endometrial cancer: a meta-analysis with trial sequential analysis of randomized controlled trials by Ji Ren, Jinghe Wang, Yanan Wang, Dongying Yang, Jianming Sheng, Shili Zhu, Yunli Liu, Xiaoqi Li, Wei Liu, Binbin Zhang

“…This study sought to assess the efficacy and safety of this therapeutic combination in patients with advanced or recurrent EC.MethodsWe performed an exhaustive review of randomized controlled trials (RCTs) up to September 25, 2024, examining the efficacy and safety of combining PD-1/PD-L1 inhibitors with CT versus CT alone (or plus placebo) in advanced or recurrent EC. …”
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Effects of body weight-supported Tai Chi Yunshou training on upper limb motor function in stroke patients: A three-arm parallel randomized controlled trial. by Liying Zhang, Xiaoming Yu, Wangsheng Liao, Jiening Wang, Yan Lu, Naizhen Wang, Zhou Huanxia

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Comparison of the two treatment methods in primary hyperparathyroidism due to solitary parathyroid adenoma, Ultrasound-guided percutaneous alcohol ablation vs. parathyroidectomy: a randomized controlled trial by Mohammad Eslamian, Babak Tavakoli, Alireza Firouzfar, Alireza Pouramini, Bijan Iraj, Mohsen Kolahdouzan, Marjan Mansourian

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Injection of Lidocaine Alone versus Lidocaine plus Dexmedetomidine in Impacted Third Molar Extraction Surgery, a Double-Blind Randomized Control Trial for Postoperative Pain Evaluation by Javad Alizargar, Milad Etemadi Sh, Nasser Kaviani, Shu-Fang Vivienne Wu, Keyvan Jafarzadeh, Parisa Ranjbarian, Nan-Chen Hsieh

“…This double-blind randomized control trial study evaluated postoperative pain and associated factors following impacted third molar extraction surgery. …”
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Treatment Options for Advanced Non-Small Cell Lung Cancer After Failure of Previous Immune Checkpoint Inhibitors and Chemotherapy: Meta-Analysis of Five Randomized Controlled Trials by Andrea Messori, Andrea Ossato, Lorenzo Gasperoni, Luna Del Bono, Alessandro Inno, Vera Damuzzo

“…Methods: We undertook a meta-analysis that compared combination regimens with the current standard of care. Only randomized controlled trials (RCTs) were included (endpoint, overall survival [OS]). …”
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Response to Comment by Dr. Kuang on Our Manuscript “Immediate Oral Refeeding in Patients With Mild and Moderate Acute Pancreatitis: A Multicenter, Randomized Controlled Trial (PADI trial)” by Elena Ramírez-Maldonado, MD, PhD, Sandra López Gordo, MD, PhD, Robert Memba, MD, PhD, Rosa Jorba, MD, PhD, on behalf of the Catalan Pancreatitis Collaborative Group, Laia Blanco, Sandra M. Bacca, Joaquim Balsells, Carme Boqué, Pablo Collera Ormazabal, Daniel Coronado Llanos, Ignasi Elizalde, Laia Estalella, Maria Teresa Fernández Planas, Lidia Florit Serra, Inmaculada Fonoll, Nil Gómez Vallvé, Sergio González, Maria Alejandra Guerrero Ortíz, Jiazhen Li, Erik Llàcer-Millán, Rui Pedro Major Branco, David Nicolas, Elizabeth Pando, Mihai-Calin Pavel, Jing Quiao, Marta Rodrigo-Rodrigo, Ariadna Sánchez, Teresa Soriano, Guillem Soy, Eva Vaquero, Pengyu Wu, Heng Xi, Wen Zhong

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Effects of the Proactive Interdisciplinary Self-Management (PRISMA) Program on Online Care Platform Usage in Patients with Type 2 Diabetes in Primary Care: A Randomized Controlled Trial by Esther du Pon, Nanne Kleefstra, Frits Cleveringa, Ad van Dooren, Eibert R. Heerdink, Sandra van Dulmen

“…Therefore, the objective of the current study was to investigate whether a group education program can improve the use of an online care platform in patients with T2DM treated by primary care providers in the Netherlands. In a randomized controlled trial, patients with T2DM received either PRISMA with usual care or usual care only. …”
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Commentary on the systematic review: Models of care for improving health-related quality of life, mental health, or mortality in persons with multimorbidity: A systematic review of randomized controlled trials by Christian U Eriksen, Nina Kamstrup–Larsen, Hanne Birke, Sofie A L Helding, Nermin Ghith, John S Andersen, Anne Frølich

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Effect of transcutaneous electrical acupoint stimulation on length of stay for patients after undergoing surgery for colorectal cancer: a systematic review and meta-analysis of randomized controlled trials by YaDan Xiao, Fei Yang, JunLiang Zhou, YuanLing Huang, YaXin Xiao

“…ObjectiveThis study aimed to examine the effect of transcutaneous electrical acupoint stimulation (TEAS) on the length of stay (LOS) of patients undergoing surgery for colorectal cancer.MethodsA systematic review was conducted by searching databases, including PubMed, Embase, Cochrane Library, China Network Knowledge Infrastructure, and Wanfang Database for randomized controlled trials (RCTs) published up to August 24, 2024. …”
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Comparison of intraoperative neurophysiological monitoring between propofol and remimazolam during total intravenous anesthesia in the cervical spine surgery: a prospective, double-blind, randomized controlled trial by Myoung Hwa Kim, Jinyoung Park, Yoon Ghil Park, Yong Eun Cho, Dawoon Kim, Dong Jun Lee, Kyu Wan Kwak, Jongyun Lee, Dong Woo Han

“…Methods In this prospective, double-blind, randomized controlled trial, 64 patients requiring IONM during cervical spine surgery were administered either propofol (Group P) or remimazolam (Group R). …”
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Effectiveness of breathing exercises on urinary symptoms, muscle activity, and strength in women with multiple sclerosis and urinary incontinence—a study protocol for a randomized controlled trial study by Atieh Nazem, Shabnam ShahAli, Mehdi Dadgoo, Holakoo Mohsenifar, Ismail Ebrahimi Takamjani, Laleh Abadi Marand

“…Methods Fifty women with MS and UI will participate in this parallel randomized controlled trial, comprising 32 treatment sessions. …”
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The Health‐Related Quality of Life for Cemented Versus Uncemented Hemiarthroplasty in Elderly Patients With Femoral Neck Fractures: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials by Mohanad Samaheen, Maen Mohammad, Mikhail Salzmann, Nikolai Ramadanov

“…Methods We searched PubMed, Embase, and Cochrane databases for randomized controlled trials (RCTs) comparing cemented with uncemented hemiarthroplasty in patients aged 50 years and older with femoral neck fractures. …”
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Costs of home-delivered antiretroviral therapy refills for persons living with HIV: Evidence from a pilot randomized controlled trial in KwaZulu-Natal, South Africa. by Ashley S Tseng, Ruanne V Barnabas, Alastair van Heerden, Xolani Ntinga, Maitreyi Sahu

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Clinical Efficacy of Curcumin and Vitamin E on Inflammatory-Oxidative Stress Biomarkers and Primary Symptoms of Menopause in Healthy Postmenopausal Women: A Triple-Blind Randomized Controlled Trial by Azizeh Farshbaf-Khalili, Alireza Ostadrahimi, Mojgan Mirghafourvand, Khatereh Ataei-Almanghadim, Sara Dousti, Amir Mehdi Iranshahi

“…The present study is a triple-blind parallel randomized controlled trial. Eighty-four eligible postmenopausal women aged 40 to 60 years old were randomly assigned into three groups using block randomization with an allocation ratio of 1 : 1 : 1. …”
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Study Protocol for the Hand OsteoArthritis Self-Management and Integrated Scheme (OASIS-H) to Improve Outcomes in Patients with Hand Osteoarthritis—an Open-Label Randomized Controlled Trial by Iris Yan Ki Tang, Lai Man Tang, Brian Ho, Joyce Wong, Amanda Lau, Suet Kei Kwok, Carmen Tze Kwan Ho

“…In this open-label, randomized controlled trial, symptomatic OA hand patients are included and randomized into early intervention and routine clinical care groups. …”
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Efficacy of Weekly Split versus Single Doses of Ergocalciferol on Serum 25-Hydroxyvitamin D among Patients on Continuous Ambulatory Peritoneal Dialysis: A Randomized Controlled Trial by Naowanit Nata, Jessada Kanchanasinitth, Pamila Tasanavipas, Ouppatham Supasyndh, Bancha Satirapoj

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A systematic review of Randomized Controlled Trials about some non-pharmacological interventions for treatment of hypertension: Physical exercise, sodium restriction, weight and alcohol use reduction by Amobi Akonobi, Jawad Khan

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