A Six-Month Randomized Controlled Trial of Whole Soy and Isoflavones Daidzein on Body Composition in Equol-Producing Postmenopausal Women with Prehypertension by Zhao-min Liu, Suzanne C. Ho, Yu-ming Chen, Jean Woo

“…Methods. 270 eligible women were randomized to either one of the three treatments: 40 g soy flour (whole soy group), 40 g low-fat milk powder + 63 mg daidzein (daidzein group), or 40 g low-fat milk powder (placebo group) daily each for 6 months. …”
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Comparison of three cryotherapy techniques for early post-TKA pain control in terms of efficacy and patient satisfaction: a randomized controlled trial by Keerati Chareancholvanich, Worawut Keesukpunt, Chaturong Pornrattanamaneewong, Rapeepat Narkbunnam, Atthakorn Jarusriwanna

“…Methods This prospective randomized study included 108 patients who were scheduled for primary unilateral TKA. …”
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A consort‐guided randomized, blinded, controlled clinical trial on the effects of 6 weeks training on heart rate variability in thoroughbred horses by Emma Santosuosso, Renaud Léguillette, Sierra Shoemaker, Ryan Baumwart, Sierra Temple, Kaneesha Hemmerling, Tessa Kell, Warwick Bayly

“…Animals Twelve healthy untrained thoroughbreds were randomly split into a training group (6 weeks of incremental racetrack training) and a control group (no training). …”
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Acupuncture Dosage and Its Correlation with Effectiveness in Patients with Chronic Stable Angina: A Systematic Review and Meta-Analysis of Randomized Controlled Trial by Huang D, Li Y, Zheng X, Hu J, Tang H, Yin Y, Wu Z, Kong L

“…Dajun Huang,1,* Yanwei Li,1,* Xiaoyan Zheng,2,3,* Jinming Hu,1 Hanzhang Tang,1 Yongjun Yin,1 Zhou Wu,1 Lingqiu Kong1 1Department of Cardiovascular Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Clinical Research Center for Acupuncture and Moxibustion in Sichuan province, Sichuan JinXin Xinan Women’s and Children’s Hospital, Chengdu, People’s Republic of China; 3Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lingqiu Kong; Zhou Wu, Department of Cardiovascular Medicine, Hospital of Chengdu University of Traditional Chinese Medicine, Address: No. 39 Shi’er Qiao Road, Chengdu, Sichuan, 610023, People’s Republic of China, Email klq521@163.com; 1209293923@qq.comObjective: This systematic review aimed to compare the efficacy of various acupuncture dosages for Chronic Stable Angina (CSA) using randomized controlled trials (RCTs), addressing the unclear relationship between dosage and effectiveness despite acupuncture’s potential.Methods: We searched eight bibliographic databases from inception to October 31, 2024, evaluating RCTs comparing acupuncture to placebo or standard care for CSA patients, focusing on angina attack frequency as the primary outcome. …”
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Short-term effects of brief stair climbing interruptions on postprandial hyperglycemia during prolonged sitting: a randomized cross-over trial by Eswaran Thirunavukkarasu, Manaswi Reddy Aerva, Baskaran Chandrasekaran, G. Arun Maiya, Chythra R. Rao

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Effect of intraoperative noise isolation on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: protocol for a randomized controlled trial by Chong Fu, Fan Xia, Zihan Yan, Han-bing Xu, Wei-ming Zhao, Yi-shan Lei, Chang Xu, Wen-wen Huo, Duo-duo Tao, Juan Wang, Xi-sheng Shan, Ke Peng, Hong Liu, Fu-hai Ji, Hua-yue Liu

“…Method This single-center, prospective, randomized controlled trial will enroll 192 adult patients undergoing laparoscopic gynecological surgery. …”
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Enhancing trauma cardiopulmonary resuscitation simulation training with the use of virtual reality (Trauma SimVR): Protocol for a randomized controlled trial. by Josef Michael Lintschinger, Philipp Metelka, Lorenz Kapral, Florian Kahlfuss, Lena Reischmann, Alexandra Kaider, Caroline Holaubek, Georg Kaiser, Michael Wagner, Florian Ettl, Leonhard Sixt, Eva Schaden, Christina Hafner

“…<h4>Methods and analysis</h4>This study protocol (clinicaltrials.gov identifier: NCT06445764) for a single-center, prospective, randomized, controlled trial focuses on first-year residents in anesthesiology/intensive care, traumatology, and emergency medicine. …”
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Regenerative potential of concentrated growth factor compared to platelet-rich fibrin in treatment of necrotic mature teeth: a randomized clinical trial by Taghreed Salah, Wael Hussein, Heba Abdelkafy

“…Abstract Aim This study aimed to compare the potential of two regenerative endodontic procedures, platelet-rich fibrin (PRF) and concentrated growth factor (CGF), in the treatment of mature permanent teeth with necrotic pulps and periapical radiolucency. Methods This randomized clinical trial was written according to the Preferred Reporting Items for Randomized Trials in Endodontics 2020 guidelines. …”
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Can handheld ultrasound probes reliably measure transabdominal prostate and bladder volumes? A prospective randomized point-of-care ultrasound study by Henry C. Wright, Dillon Corrigan, Smita De

“…Measurement of PGV with handheld ultrasound (HUS) probes shows promise.ObjectiveTo compare the reliability of two HUS probes (Butterfly iQ and Clarius C3) to the BPH guideline-recommended imaging (GIm) for both prostate and bladder volumetrics.MethodsMale patients with GIm were randomized to undergo transabdominal HUS PGV with one of the two probes. …”
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The effects of training female students in emotion regulation techniques on their social problem-solving skills and social anxiety: a randomized controlled trial by Ashraf Akbari, Camellia Torabizadeh, Narjes Nick, Giti Setoodeh, Parvin Ghaemmaghami

“…Method This study was a randomized controlled trial conducted in Iran, utilizing a pretest-posttest design with control and intervention groups. …”
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23 Efficacy and safety of trans-obturator tape vs. urethral bulking in female stress urinary incontinence. A randomized controlled trial by E. Costantini, E. Illiano

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In vivo mitochondrial ATP production is improved in older adult skeletal muscle after a single dose of elamipretide in a randomized trial. by Baback Roshanravan, Sophia Z Liu, Amir S Ali, Eric G Shankland, Chessa Goss, John K Amory, H Thomas Robertson, David J Marcinek, Kevin E Conley

“…Here, we describe the impact of a first-in-class cardiolipin-binding compound that is targeted to mitochondria and improves oxidative phosphorylation capacity (Elamipretide, ELAM) in a randomized, double-blind, placebo-controlled clinical trial.…”
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Comparison of ropivacaine with ropivacaine–dexamethasone combination for postoperative analgesia in the pectoral nerve block for modified radical mastectomy: A randomized clinical trial by Veena Mathur, Brijesh Kumari, Anand Kumar Verma, Arvind Khare, Deepak Kumar Garg

“…Methods: This prospective, randomized, double-blind study was conducted on a total of 80 women with breast cancer belonging to American Society of Anesthesiologist class I and II scheduled for MRM, which were randomly allocated into two groups – Group R (n = 40) received 0.25% ropivacaine 29 ml + NS 1 ml and Group RD (n = 40) received 0.25% ropivacaine 29 ml + dexamethasone (4 mg) 1 ml. …”
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Relationship between major depressive disorder and myalgic encephalomyelitis/chronic fatigue syndrome: a two-sample mendelian randomization study analysis by Wenjing Song, Xinlei Hou, Minmin Wu, Luwen Zhu

“…To investigate the potential genetic causal link between these conditions, we conducted a two-sample Mendelian randomization (MR) analysis. Summary data from Genome-Wide Association Studies (GWAS) for MDD were sourced from the UK Biobank and the Psychiatric Genomics Consortium, while GWAS data for ME/CFS were retrieved from the UK Biobank. …”
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High-flow nasal cannula oxygen therapy versus non-invasive ventilation in healthy respiratory physicians: a non-randomized study by Hong Ye, Dandan Xiang, Xiangyu Zhu, Xiuwei Du, Shengyun Shang, Jing Xu, Yu Li, Yunyun Cheng, Zhongfei Yang

“…This study aims to first establish whether to use HFNC or NIV based on comfort levels, and subsequently evaluate diaphragmatic function under equivalent comfort levels to determine the optimal modality for clinical application.MethodsA self-controlled, non-randomized study was conducted with 10 healthy respiratory physicians as participants. …”
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An Analysis of the Impact of Digital Therapeutic Interventions on Attention and Working Memory in Children with Attention-Deficit/Hyperactivity Disorder: A Randomized Controlled Trial by Seon-Chil Kim, Hojun Lee

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Lumbar Erector Spinae Plane Block for Total Hip Arthroplasty Comparing 24-Hour Opioid Requirements: A Randomized Controlled Study by Dahlia Townsend, Nasir Siddique, Atsumi Kimura, Yaacov Chein, Eli Kamara, John Pope, Mitchell Weiser, Singh Nair, Iyabo Muse

“…Thirty-one patients were randomized to the control group (spinal alone) and 32 patients to the ESPB group. …”
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Results of the ORION open comparative randomized trial: evaluation of efficacy of the Russian drugs Altevir and Phosphogliv in combined treatment of chronic hepatitis C by V. T. Ivashkin, M. V. Mayevskaya, P. O. Bogomolov, I. G. Nikitin, A. O. Buyeverov, A. V. Lapshin

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Topical riboflavin versus 5-aminolevulinic acid photodynamic therapy for the treatment of mild to moderate acne: A split-face randomized study by Aijia Ding, Li Shi, Feng Jiang, Chong Wang, Jianglin Zhang

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Use of a Non-Pharmacological Pain Relief Kit to Reduce Opioid Use Following Orthopedic Surgery: A Prospective Randomized Study by Denis J O'Hara, Timothy F Tyler, Malachy P McHugh, Susan Y Kwiecien, Tyler Bergeron

“… # Level of Evidence 2b # Methods Fifty-three subjects (18 women, 35 men) having orthopedic surgery were randomly assigned to either receive the Pain Relief Kit (treatment) or control group. …”
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