Evaluation of long‐acting cabotegravir safety and pharmacokinetics in pregnant women in eastern and southern Africa: a secondary analysis of HPTN 084 by Sinead Delany‐Moretlwe, Brett Hanscom, Xu Guo, Clemensia Nkabiito, Patricia Mandima, Patricia Ntege Nahirya, Juliet Mpendo, Muchaneta Bhondai‐Mhuri, Nyaradzo Mgodi, Rebecca Berhanu, Jennifer Farrior, Estelle Piwowar‐Manning, Susan L. Ford, Craig W. Hendrix, Alex R. Rinehart, James F. Rooney, Adeola Adeyeye, Raphael J. Landovitz, Myron S. Cohen, Mina C. Hosseinipour, Mark A. Marzinke, the HPTN 084 Study Team

“…Methods Participants were randomized 1:1 to either active cabotegravir (CAB) plus tenofovir disoproxil fumarate/emtricitabine (TDF/FTC) placebo or active TDF/FTC plus CAB placebo. …”
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Acupoint application of Xiefu prescription in the prevention of functional constipation in long-term bedridden patients with pelvic fracture (泻腑贴方穴位贴敷预防长期卧床骨盆骨折患者功能性便秘的临床研究)... by GU Tianjiao (顾天姣), LIU Yingchun (刘迎春), DONG Ziqing (董子青), DING Di (丁娣), DENG Lixia (邓丽霞), YANG Yanhui (杨燕辉), MAO Lingling (毛玲玲)

“…Methods A total of 60 patients with pelvic fracture without abnormal defecation function and constipation main symptom score ≤3 were selected and randomly divided into two groups: 30 patients in the control group received routine prevention and nursing measures, and 30 patients in the treatment group received acupoint application of Xiefu prescription based on the routine nursing interventions. …”
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Initial clinical experience with [177Lu]Lu-PNT2002 radioligand therapy in metastatic castration-resistant prostate cancer: dosimetry, safety, and efficacy from the lead-in cohort o... by Aaron R. Hansen, Stephan Probst, Jean-Mathieu Beauregard, Benjamin L. Viglianti, Jeff M. Michalski, Scott T. Tagawa, Oliver Sartor, Ronald F. Tutrone, Orhan K. Oz, Kevin D. Courtney, Ebrahim S. Delpassand, Luke T. Nordquist, Medhat M. Osman, Kim N. Chi, Richard Sparks, Noble George, Sara M. Hawley, Wenting Wu, Jessica D. Jensen, Neil E. Fleshner

“…This study leveraged a lead-in phase to assess tissue dosimetry and evaluate preliminary safety and efficacy, prior to expansion into a randomized phase. Here we report those results.MethodsEnrolled participants had mCRPC that progressed on one prior androgen receptor pathway inhibitor (ARPI), were prostate-specific membrane antigen (PSMA) PET–positive as determined by a central reader, were chemotherapy-naïve for mCRPC, and had adequate bone marrow and end-organ reserve. …”
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Application of M3 nickel-titanium files in one-time root canal therapy for the elderly patients and nursing effect evaluation (M3机用镍钛锉在老年患者一次性根管治疗中的应用及护理效果评价)... by LUAN Xiaoyu (栾晓宇), LI Yuling (李玉玲), ZHANG Weihong (张卫红), WANG Qian (王倩)

“…Methods Totally 160 elderly patients with chronic pulpitis who needed root canal therapy were treated with one-time root canal therapy. They were randomly divided into two groups with 80 cases in each group, including premolars and molars. …”
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Effect of Traditional Chinese Medicine ointment rubbing in the treatment of hypermyotonia after cerebral infarction (中药膏摩治疗脑梗死后肌张力增高的临床研究) by YUAN Yonge (袁永娥), YANG Junxing (杨俊行), FU Jingna (付景娜), SU Rong (苏容), ZHANG Bing (张兵), CHEN Chen (陈程), XU Dong (徐栋)

“…Methods Totally 92 patients with hypermyotonia after cerebral infarction were selected and randomly divided into control group (n = 46) and treatment group (n = 46). …”
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Elevating larval source management as a key strategy for controlling malaria and other vector-borne diseases in Africa by Fredros Okumu, Sarah J. Moore, Prashanth Selvaraj, Arnon Houri Yafin, Elijah O. Juma, GloriaSalome G. Shirima, Silas Majambere, Andy Hardy, Bart G. J. Knols, Betwel J. Msugupakulya, Marceline Finda, Najat Kahamba, Edward Thomsen, Ayman Ahmed, Sarah Zohdy, Prosper Chaki, Peter DeChant, Kimberly Fornace, Nicodem Govella, Steven Gowelo, Emmanuel Hakizimana, Busiku Hamainza, Jasper N. Ijumba, William Jany, Hmooda Toto Kafy, Emmanuel W. Kaindoa, Lenson Kariuki, Samson Kiware, Eliningaya J. Kweka, Neil F. Lobo, Dulcisária Marrenjo, Damaris Matoke-Muhia, Charles Mbogo, Robert S. McCann, April Monroe, Bryson Alberto Ndenga, Halfan S. Ngowo, Eric Ochomo, Mercy Opiyo, Richard Reithinger, Chadwick Haadezu Sikaala, Allison Tatarsky, David Takudzwa, Fedra Trujillano, Ellie Sherrard-Smith

“…In this paper, we argue that the heavy reliance on large-scale cluster-randomized controlled trials (CRTs) to generate evidence on epidemiological endpoints restricts the recommendation of approaches to only those interventions that can be measured by functional units and deliver relatively uniform impact and, therefore, are more likely to receive financial support for conducting these trials. …”
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Effect and Mechanism of Swimming Exercise Preconditioning on Neurological Function of Mice with Intracerebral Hemorrhage by LI Yongxu, LIN Libin, LU Taotao, WEI Wei, LIN Zhicheng, XUE Xiehua

“…ObjectiveTo observe the effect of swimming exercise preconditioning on neurological function and expression levels of brain derived neurotrophic factor (BDNF), serine-threonine kinase (Akt) and peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) proteins in perihematoma tissues of mice with intracerebral hemorrhage (ICH).MethodsA total of 60 male C57BL/6 mice were randomly divided into sham group, ICH 7 d group, SEP+ICH 7 d group (preconditioning group 1), ICH 14 d group and SEP+ICH 14 d group (preconditioning group 2), with 12 cases in each group. …”
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Effect of acupoint application combined with acupoint massage on constipation of liver-qi stagnation after replantation of severed fingers (穴位贴敷联合按摩在断指再植术后肝郁气滞型便秘患者中的应用效果研究)... by TIAN Miaomiao (田苗苗), XIAO Junyan (肖俊艳)

“…Methods Totally 60 patients with constipation of liver-qi stagnation after finger replantation were randomly divided into study group and control group, with 30 patients in each group. …”
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Effects of dietary compound acidifier (Biomin) on the growth, anti-oxidation, immunity, and intestinal health of juvenile channel catfish (Ictalurus punctatus) by Junyu Yan, Kai Luo, Bo Wang, Jiaxin He, Can Li, Jiang Zhou, Wenhao Lai, Xin Zhou, Jingwei Ye, Mingzhu Pan, Yingbing Su, Weihua Gao, Kai Guo, Chengmin Zhao

“…A total of 648 fish with similar initial body weight (143.77 ± 0.73 g) were randomly placed into 18 tanks, with 36 fish in each tank. …”
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Immune response and growth of Lates calcarifer fed on hydrolized protein-supplemented diet by Romi Novriadi, Tinggal Hermawan, , Ibtisam, , Dikrurrahman, Muh Kadari, Mikael Herault, Vincent Fournier, Paul Seguin

“…The experiment was performed in two different rearing period, namely nursery and grow out by using completely randomized design. Experimental fish were fed with three types of diets and each treatment was repeated three times: a local commercial diet (control), coated or not, with 2%, and 3% of protein hydrolysates. …”
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Grain Yield Stability Analysis of Lentil Genotypes by AMMI Indices by Payam Pezeshkpour, Reza Amiri, Iraj Karami, Amir Mirzaei

“…Methods: In this study, 12 promising lentil genotypes along with “local”, “Kimia”, and “Gachsaran” cultivars were cultivated in a randomized complete block design for three consecutive cropping years (2019-2022) in Lorestan/Khoramabad, Ilam/Chardavel, and Kermanshah/Sararood. …”
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Intervention effect and mechanism of Dracocephalum moldavica L. extract on bleomycin-induced pulmonary fibrosis in rats by Xiaoyu SUN, Li CHEN, Ruifang GAO, Hui YU, Min JIN

“…Thirty-two rats were randomly divided into a control group, a model group, a low-dose group of Dracocephalum moldavica L. extract (100 mg·kg−1), and a high-dose group of Dracocephalum moldavica L. extract (400 mg·kg−1), with eight rats in each group. …”
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Application of finger-pressing on Tiantu acupoint to induce cough in postoperative patients with early-stage lung cancer (指压天突穴引咳法在早期肺癌术后患者中的应用)... by BIAN Guanjun (边冠军), ZHANG Chunmei (张春梅), LIU Lifeng (刘丽峰)

“…Methods Totally 100 patients with peak expiratory flow (PEF) ≤5. 33L/s who were admitted to the Hospital from January 2023 to March 2023 were randomly divided into observation group and control group, with 50 cases in each group. …”
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A phase 2, double-blind, placebo-controlled trial of a valproate/lithium combination in ALS patients by M.-C. Boll, M. Alcaraz-Zubeldia, C. Rios, D. González-Esquivel, S. Montes

“…Methods: Outpatients with a typical ALS presentation were enrolled in a randomized, placebo-controlled trial to assess the efficacy of orally administered VPA-Li. …”
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A Predictive Model for Pulmonary Aspergillosis in ICU Patients: A Multicenter Retrospective Cohort Study by Li Y, Ren X, Wang Q, Shen S, Li Y, Qian X, Tang Y, Jia J, Zhang H, Ding J, Song Y, Zhang S, Wang S, Xu Y, Jiang Y, He X, Dai M, Zhong L, Xiong Y, Pan Y, Wang M, Shao H, Cai H, Huang L, Wang H

“…Subsequently, patients were randomly assigned to training and validation cohorts in a 7:3 ratio. …”
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Study on the improvement of behavior and pain and the mechanism of Yangpafang in subacute Parkinson's disease model mice by SHI Ying, MEI Shan‐shan, WANG Yuan‐ling, XIA A‐long, WANG Xiao‐wei, LI Jun

“…Methods Total 42 specific pathogen⁃free (SPF) C57BL/6J mice were randomly divided into control group, model group, Yangpafang low⁃ dose group [13.50 g/(kg·d)], medium ⁃dose group [40.50 g/(kg·d)] and high⁃dose group [121.50 g/(kg·d)], levodopa and benserazide group (7 mice in each group). …”
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Study on the application of modified Baduanjin exercise in accelerating rehabilitation of patients with tuberculosis of lumbar spine (改良八段锦在腰椎结核患者加速康复中的应用研究)... by TANG Ling (唐玲), TAN Jiarong (谭佳容), TANG Yang (唐阳), HE Jing (何静), MU Lianghai (穆浪海)

“…Methods Totally 66 patients with tuberculosis of lumbar spine were randomly divided into study group and control group. …”
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Curative effect of auricular copper scraping combined with auricular acupoint pressing on insomnia after Methylprednisolone pulse therapy for thyroid-associated ophthalmopathy (耳部铜... by MA Yan (马艳), ZHAO Yue (赵悦), LIN Yuxiao (林育潇), LIU Xiao (刘笑), SONG Yumin (宋玉敏)

“…Objective　Methods 82 patients diagnosed with thyroid-associated ophthalmopathy who needed hormone pulse therapy were randomly divided into control group and observation group according to numerical method, with 41 cases in each group. …”
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A Comparative Study of Health Efficacy Indicators in Subjects with T2DM Applying Power Cycling to 12 Weeks of Low-Volume High-Intensity Interval Training and Moderate-Intensity Con... by Jun Li, Wei Cheng, Haifeng Ma

“…Exercise prescription was determined based on T2DM exercise guidelines combined with medical diagnosis and exercise test results, and the patients were randomly assigned to three groups: HIIT group, MICT group, and control (CON) group. …”
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Genetic Analysis of Reciprocal Crosses of Silkworm in New Iranian Lines and Hybrids by Shahla Nematollahian, Seyed Hossein Hosseini Moghaddam, Babak Rabiei, Seyed Ziaeddin Mirhoseini

“…All lines (12 genotypes) and 72 hybrids (36+36) were reared in a completely randomized design with 4 replications. All stages of hatching and rearing of silkworm lines and hybrids in this project were done in the same way based on standard methods. …”
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