Recent advances in systemic therapy for advanced biliary tract cancer: A systematic review and meta-analysis using reconstructed RCT survival data by Zhihao Li, Daniel Aliseda, Owen Jones, Luckshi Rajendran, Christian Magyar, Robert Grant, Grainne M. O’Kane, Anna Saborowski, Gonzalo Sapisochin, Arndt Vogel

“…Methods: Our systematic review included studies from five databases focusing on English-language articles published between January 2010 and June 2024. We included randomized clinical trials (RCTs) that featured GemCis in a treatment arm for treatment-naive adults with advanced BTCs. …”
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Association of rs3755319 and rs4148325 of the <i>UGT1A1</i> gene, rs2328136 of the <i>NUP153-AS</i> gene, and rs16928809 of the <i>SLC22A18</i> gene with benign unconjugated hyperb... by Anastasiya A. Ivanova, Natalia E. Apartseva, Anastasiia P. Kashirina, Elena G. Nemcova, Julija V. Ivanova, Margarita V. Kruchinina, Svetlana A. Kurilovich, Vladimir N. Maksimov

“…Methods: This case-control study included a group of individuals with benign unconjugated hyperbilirubinemia (n = 414, mean age 36.7 ± 15.9 years, 49.8% men) and a control group (n = 381, mean age 39.1 ± 15.9 years, 52.5% men). The sample was randomly selected from the participants of the MONICA project, screening of young people aged 25–44 years and a cross-sectional study of schoolchildren in Novosibirsk. …”
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Evaluation of Yield and Yield Components of Different Ecotypes of Black Cumin (Nigella sativa L.) to Planting Date in Gorgan by Mohammad Sadeq Ashrafi, Farshid Ghaderi-Far, Elias Soltani, Ebrahim Zeinali, Asieh Siahmarguee

“…The experiment was carried out in the form of split plots based on completely randomized block statistical design with three replication, in which four planting dates were 18th December, 17th January, 16th February and 18th March as the main plot and thirteen ecotypes (Such as Tafaresh, Gardmiran, Razan, Hamedan, Arak, Esfahan, Semirom, Eqlid, Ashkazar, Zabol, Bajestan, Sarayan and Khaf) with 3 replication were considered as sub-plot. …”
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Comparison of Hyperbaric 0.5% Levobupivacaine and Hyperbaric 0.75% Ropivacaine for Intrathecal Use in Infraumbilical Surgeries: A Randomised Clinical Study by Tejash H Sharma, Jagrati Jain, Priya Kishnani, Richa Tailor, Sara Mary Thomas

“…Patients with American Society of Anaesthesiologists (ASA) I/II status were randomly allocated into two equal groups of 20 each. …”
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Jiangu Granules Regulates Endoplasmic Reticulum Stress-Induced Apoptosis in UMR-106 Cells by Modulating the PERK/eIF2α/ATF4/CHOP Pathway by CHEN Sainan, ZHOU Fen, HUANG Yunmei, LIN Yanping

“…UMR-106 cells exhibiting favorable growth status were randomly allocated into four groups: negative control group (NC group), model group (H₂O₂ group), Jiangu Granules group (H₂O₂+JG group), and positive control group (H₂O₂+GSK2606414 group). …”
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Assessing Facial Thermal Nociceptive Response in Female Dogs After Elective Ovariohysterectomy Anesthetized with Isoflurane and Treated with Cannabidiol and Meloxicam Analgesia by Alejandro Casas-Alvarado, Patricia Mora-Medina, Ismael Hernández-Avalos, Julio Martínez-Burnes, Agatha Miranda-Cortes, Adriana Domínguez-Oliva, Daniel Mota-Rojas

“…Sixty-four female dogs of different breeds were randomly distributed into four study groups according to the treatment received. …”
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Effects of early pulmonary rehabilitation exercise on the lung function and indicators of arterial blood gas analysis in patients with severe chronic obstructive pulmonary disease... by XU Nannan (徐楠楠), HONG Hanhan (洪涵涵)

“…Methods Seventy patients with severe COPD undergoing pulmonary rehabilitation were selected as the study objectis, and were randomly divided into the observation group and the control group, with 35 patients in each group. …”
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Feasibility study of ‘Triple-Low’ technique for coronary artery computed tomography angiography (CCTA) by Shaochuan Wang, Zhengwen Sun, Yihong Zeng, Xinyu Xu, Yan Wang, Xueqin Liu, Yonggui Yang

“…We prospectively collected data from 90 patients who underwent CCTA at our hospital between 2021 and 2024. The patients were randomly assigned to either the experimental group (n = 45) or the control group (n = 45). …”
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Investigating the Effect of Different Levels of Butyric Acid Glycerides and Clove Oil on Growth Performance, Blood Parameters and Tibia Bone Characteristics of Broiler Chickens by Seyyedeh azam khatami, Mir Daryoush Shakouri, Nemat Hedayat Evrigh

“…Material and Methods: A total of 300 male and female broilers (Ross 308) with a completely randomized design with a 2 × 3 factorial arrangement, two levels of butyric acid glycerides (0 and 0.2 %) and three levels of clove oil (0, 500 and 1000 mg/kg) were used. …”
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Early and high-volume administration of sodium bicarbonate in sepsis-associated acute kidney injury in patients with malignancies, during continuous renal replacement therapy by Lamei Ouyang, Yin Pan, Ya-Fei Wu, Qiang Tang, Dao-Feng Wang, Ning Lou

“…Furthermore, the duration of mechanical ventilation (7.0 ± 3.33 days) was lower in the early high-volume group compared to the other groups (8.0 ± 1.12 days,10.0 ± 1.11 days, and 8.0 ± 2.65 days; χ2 =8.064, p = 0.045), as was the length of ICU stay (7.0 ± 0.89 days) compared to the other groups (13.0 ± 3.35 days, 10.0 ± 1.49 days, and10.0 ± 3.70 days; χ2 = 9.184, p = 0.027).Conclusion Early and high-volume administration of sodium bicarbonate during CRRT may reduce 28-day mortality and improve shock reversal rates in patients with sepsis-associated acute kidney injury complicated by malignancy. Prospective randomized controlled large sample studies are needed to confirm this.…”
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Effect of auricular holographic copper-plate scrapping combined with auricular acupoint pressing therapy in the treatment of nonspecific low back pain of cold-dampness obstruction... by REN Fang (任芳), ZHOU Haiying (周海英), BAI Yang (白洋), LI Lijuan (李利娟)

“…Methods Totally 90 patients with nonspecific low back pain of cold-dampness obstruction type were randomly divided into the control group and observation group, with 45 cases in each group. …”
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Effect of Exercise Preconditioning on Myocardia Ischemia-Reperfusion Injury in Aged Rats by Hongyu LI, Xia YIN, Shiqiang ZHANG, Luwen ZHU, Qiang TANG

“…Objective:To observe the effects of exercise preconditioning on cardiac function, myocardial infarct area, cardiomyocyte ultrastructure and antioxidant capacity of aged rats after isolated myocardial ischemia-reperfusion injury.Methods:A total of 60 SPF male SD aged rats were randomly divided into the control group (Con group), the ischemia-reperfusion model group (IR group), the exercise preconditioning+ischemia-reperfusion group (EP+IR group), the ischemic preconditioning group (IPC group) and the exercise preconditioning+ischemic preconditioning group (EP+IPC group), with 12 rats in each group. …”
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Risk Factors of Portal Vein Thrombosis in Patients with Different Child-Pugh Classes Liver Cirrhosis by M. Yu. Nadinskaia, Kh. B. Kodzoeva, K. A. Gulyaeva, M.-D. E. Khen, D. I. Koroleva, M. A. Privalov, A. Kh. Tekaeva, V. R. Fedorov, S. G. Prokofev

“…From the database of cirrhotic patients without PVT 60 Controls for class A and 205 for B/C were selected using sratified randomization by sex, age and etiology of cirrhosis. …”
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The synergetic effect of selenium or zinc oxide nanoparticles with chromium on mitigating thermal stress for sustainable production and improving antioxidant capacity and inflammat... by I. T. El-Ratel, K. H. El-Kholy, S. M. Elgmmal, S. F. Fouda, A.-K. E. Abdel-Khalek, M. A. Hassan, M. M. Azzam, M. Alagawany, A. Lestingi

“…A total of 100 newly weaned APRI rabbits were randomly divided into five homogeneous groups. A basal diet containing no feed additives (0 g per kg diet) was given to the first group, and the second, third, fourth, and fifth groups were given a diet supplemented with 0.3 mg SeNPs, 20 mg ZnONPs, 0.3 mg SeNPs and 1.5 mg Cr, and 20 mg ZnONPs and 1.5 mg Cr per kg diet, respectively. …”
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Effect of Traditional Chinese Medicine Baduanjin exercise combined with remote ischemic conditioning on mild cognitive impairment after stroke (中医传统功法八段锦联合远隔缺血适应治疗脑卒中后轻度认知障碍的效果研究)... by XUE CHAO (薛超), LI Juan (李娟), FANG Qian (方茜), CHEN Lihua (陈丽华), HAO Mingqing (郝明青), CHEN Zuoxiu (陈作秀)

“…Methods Seventy patients with mild cognitive impairment after stroke were recruited as study subjects and randomly divided into control group(n=35) and intervention group(n=35). …”
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Evaluation of corn steep liquor on the digestibility and growth performance of juvenile common carp strain Sinyonya by Dodi Hermawan, Lukman Anugrah Agung, Indah Juwita Sari, Haeru Wahyudin, Immanuel Tarigan

“…The study used a completely randomized design with four treatments and four replications. …”
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Application of five-tone music therapy combined Wu Qin Xi exercise in nursing of patients with cervical spondylosis (五音疗法联合五禽戏锻炼在颈椎病护理中的应用)... by WANG Jitao (王稷陶), SUN Yanrong (孙艳荣), WANG Jiating (王佳婷), LIU Ying (刘营), ZHENG Mengqi (郑梦绮)

“…Methods Totally 82 patients with cervical spondylosis were randomly divided into the observation group and control group, with 41 cases in each group. …”
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Investigating the Effect of Chicken Manure and Potassium Sulfate on the Physiological Properties of Fenugreek )Trigonella foenum-graecum L.( Medicinal Plant by Mohammad hossein Aminifard, Sajjad Nadafa, Hassan Hassan, Mehdi Jahani

“…Therefore, considering the mentioned cases and the lack of scientific information in the field of combining fertilizers, in this research, an attempt was made to find a suitable fertilizer combination consisting of chicken manure and potassium sulfate for the fenugreek plant.Materials and MethodsTo investigate the effect of chicken manure and potassium sulfate on the physiological characteristics of the fenugreek medicinal plant, factorial research was conducted based on randomized complete block design with three replications in the crop year 2021-2022 in Qochan city in the north of Razavi Khorasan province. …”
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Trends in Mental Health Outcomes of College Students Amid the Pandemic (Roadmap mHealth App): Longitudinal Observational Study by Gautham Jayaraj, Xiao Cao, Adam Horwitz, Michelle Rozwadowski, Skyla Shea, Shira N Hanauer, David A Hanauer, Muneesh Tewari, Kerby Shedden, Sung Won Choi

“…Future research should explore the efficacy of mHealth interventions through randomized controlled trials to further understand their impact on college students’ mental health outcomes. …”
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Short- and long-term effects of transcutaneous spinal cord stimulation on autonomic cardiovascular control and arm-crank exercise capacity in individuals with a spinal cord injury... by Samuel J E Lucas, Tom E Nightingale, Jet J C S Veldhuijzen van Zanten, Shin-Yi Chiou, Alex J Wadley, Rebekah A I Lucas, Daniel D Hodgkiss, Shane J T Balthazaar, Joseph F Welch, Phoebe A Cox

“…Thereafter, the SCI cohort will be randomly assigned to an experimental (CV-TSCS+ACE) or control (SHAM-TSCS+ACE) group. …”
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