A Randomized, Double-Blind, Placebo-Controlled Trial Protocol Using the Fuzhengxiaoliu Patch for the Management of Primary Liver Cancer Pain by Li S, Wang B, Deng J, Li H, Wu Y, Fang Y, Yan B, Chen Y

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Peripheral Repetitive Transcranial Magnetic Stimulation(rTMS) for Idiopathic Facial Nerve Palsy: A Prospective, Randomized Controlled Trial by Zicai Liu, Dongling Xie, Xin Wen, Risheng Wang, Quan Yang, Huiyu Liu, Yuchun Shao, Tingting Liu

“…Methods. 65 patients with idiopathic facial nerve palsy with the first onset were recruited and randomly divided into rTMS group and control group. …”
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Evaluation of the Effectiveness of a Psychoeducational Intervention in Treatment-Naïve Patients with Antidepressant Medication in Primary Care: A Randomized Controlled Trial by R. Casañas, R. Catalán, R. Penadés, J. Real, S. Valero, MA. Muñoz, LL. Lalucat-Jo, M. Casas

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Paracetamol did not improve the analgesic efficacy with regional block after video assisted thoracoscopic surgery: a randomized controlled trial by Sujin Kim, Seung Woo Song, Haesung Lee, Chun Sung Byun, Ji-Hyoung Park

“…Methods A total of 90 patients were randomized to receive paracetamol (1 g) or normal saline. …”
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Effects of kinesio taping in patients undergoing knee or hip arthroplasty: a systematic review and meta-analysis of randomized controlled trials by Ting Mei, Yuli Shuai, Dandong Wu, Heping Yu

“…For hip arthroplasty, the outcome focused on pain. Results: Eleven randomized controlled trials involving 774 participants met the inclusion criteria. …”
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Impact of periodontal microRNAs associated with alveolar bone remodeling during orthodontic tooth movement: a randomized clinical trial by Alessandro Polizzi, Angela Alibrandi, Antonino Lo Giudice, Alfio Distefano, Laura Orlando, Amer M. Analazi, Giuseppe Pizzo, Giovanni Li Volti, Gaetano Isola

“…Clinical parameters and gingival crevicular fluid (GCF) sampling were performed on both compression and tension sides of a random canine to be distalized (test groups) at baseline and at 1 h, 1 day, 1 month and at 3-month after OTM, while the contralateral canine served as a control group. miRNAs − 7a-3p, -7a-2-3p, -7a-5p, -21-3p, -21-5p, -100-3p, -100-5p, -125b-2-3p, -125b-5p, -200b-3p, and − 200b-5p expression was analyzed using a real-time quantitative polymerase chain reaction (RT-PCR). …”
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Over-the-scope clips vs standard endoscopic interventions for first-line treatment of NVUGI bleeding: Meta-analysis of randomized trials by Paulo Ferreira Mega, Vitor Ottoboni Brunaldi, Alexandre Moraes Bestetti, Angelo So Taa Kum, Igor Valdeir de Sousa, Marcos Eduardo Lera dos Santos, Eduardo Guimarães Hourneaux de Moura

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Therapeutic effect and potential mechanism of Fufang Danshen dripping pills for stable coronary heart disease: a randomized controlled trial by Li-qin Meng, Li-qin Meng, Pei-ying Huang, Qing-min Li, Yu-chao Feng, Yu-chao Feng, Yu-chao Feng, Ding-jian Li, Guang-long Wu, Bo-wen Ao, Guo-chao Wu, Guo-xiong Zhang, Bo-jun Chen, Bo-jun Chen, Bo-jun Chen

“…This study aims to investigate the efficacy and preliminary mechanism by which FFDS may impact the progression of SCHD.MethodsBased on randomization, we administered oral FFDS to 30 patients with SCHD in addition to conventional treatment for 30 days. …”
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The effect of caregiver opinion leaders to increase demand for evidence-based practices for youth anxiety: A cluster randomized controlled trial by Margaret E. Crane, Marc S. Atkins, Sara J. Becker, Jonathan Purtle, Gillian C. Dysart, Sydney Keller, Olivia Brauer, Sirina E. Tiwari, Thomas M. Olino, Lara Baez, John Lestino, Philip C. Kendall

“…Schools within 1.5-hr drive of Philadelphia, PA were cluster-randomized ( k  = 25; two-arm prospective randomization) to the OL condition (presented by a clinical researcher and local caregiver OL; n  = 119 participants) or the researcher-only condition ( n  = 143 participants). …”
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Yishenyangsui granule for degenerative cervical myelopathy: a randomized, double-blind, placebo-controlled trial with long-term follow-up by He Yin, Xin Chen, Zhiwei Liu, Zhiwei Liu, Bo Xu, Zhefeng Jin, Yan Liu, Baoyu Qi, Bin Tang, Ping Wang, Fanping Xu, Xu Wei, Jie Yu, Liguo Zhu, Liguo Zhu

“…ObjectiveThis randomized controlled trial aims to evaluate the efficacy and safety of Yishenyangsui granule for treating Degenerative Cervical Myelopathy.Materials and methodsA randomized, double-blind, placebo-controlled clinical trial was conducted with 152 participants recruited from three centers and randomly assigned to receive either Yishenyangsui granule or placebo. …”
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Changes in Circulating BDNF in relation to Sex, Diet, and Exercise: A 12-Week Randomized Controlled Study in Overweight and Obese Participants by M. Glud, T. Christiansen, L. H. Larsen, B. Richelsen, J. M. Bruun

“…Using a previously published 12-week randomized study, serum BDNF was assessed at baseline and after 12 weeks using an enzyme-linked immunosorbent assay method. …”
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Effects of a cardiopulmonary rehabilitation programme on submaximal exercise in Tunisian patients with long-COVID19: A randomized clinical trial by Rania Kaddoussi, Hadhemi Rejeb, Amine Kalai, Eya Zaara, Naceur Rouetbi, Zohra Ben Salah Frih, Piotr Zmijewski, Helmi Ben Saad

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Nurse Participation in Colonoscopy Observation versus the Colonoscopist Alone for Polyp and Adenoma Detection: A Meta-Analysis of Randomized, Controlled Trials by Lei Xu, Yu Zhang, Haojun Song, Weihong Wang, Sijie Zhang, Xiaoyun Ding

“…The PUBMED, EMBASE, and Cochrane Library databases were searched for randomized controlled trials (RCTs) published in English. …”
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Therapeutic Effects of BCG Vaccination on Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Yu-Chen Chang, Chien-Ju Lin, Yu-Hsuan Hsiao, Yu-Han Chang, Shu-Jung Liu, Hsin-Yin Hsu

“…Six databases were systematically searched from inception to the end of August 2019. The randomized controlled trials (RCTs) that evaluated glycemic control in response to the BCG vaccine for T1DM were enrolled. …”
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Traffic-related air pollution (TRAP) exposure, lung function, airway inflammation and expiratory microbiota: A randomized crossover study by Rongrong Xu, Yanping Zhang, Tingting Wu, Hao Liu, Jianhao Peng, Zhanshan Wang, Te Ba, Baorong Zhang, Zhigang Li, Yongjie Wei

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Effect of conservative treatment on greater trochanteric pain syndrome: a systematic review and network meta-analysis of randomized controlled trials by Si-Qi Wang, Ning-Yi Guo, Wei Liu, Hong-jie Huang, Bing-bing Xu, Jian-quan Wang

“…Network meta-analysis was performed using random effects models to evaluate the effects of treatment modalities on pain reduction and functional improvement. …”
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A Randomized Placebo-Controlled Dose-Response Trial of Muvz™ for Knee and Low-Back Support in Physically Active Adults by Kalman D, Srivastava S, Desale A, Chatte Snr MD, Nalavade RJ, Shah Snr KM, Karvir S, Bhasale S

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The effect of the MyBFF@school program on cardiorespiratory fitness in overweight and obese primary schoolchildren: a cluster randomized controlled trial by Abdul Halim Mokhtar, Muhammad Ashaari Kamarudin, Alston Choong, Lakvinder Singh, Vinotha Genisan, Abqariyah Yahya, Ruziana Mona Wan Mohd Zin, Fuziah Md. Zain, Rusidah Selamat, Zahari Ishak, Muhammad Yazid Jalaludin

“…Methods Twenty-three out of 1196 government primary schools in central Peninsular Malaysia participated in this cluster-randomized control study. Schoolchildren aged 9–11 years with a body mass index (BMI) z-score greater than + 1 SD (WHO) were eligible for the study. …”
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A Randomized Trial to Evaluate the Sustained Efficacy of a Mucus Clearance Device in Ambulatory Patients with Chronic Obstructive Pulmonary Disease by Norman Wolkove, Marc A Baltzan, Hany Kamel, Michael Rotaple

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Comment on “Long-Term Outcome of Immediate Versus Postponed Intervention in Patients With Infected Necrotizing Pancreatitis (POINTER)”: Multicenter Randomized Trial by Shuirong Lin, MD, Ziming Song, MD, PhD, Xi Yu, MD, Wenxuan Xie, MD,PhD, Shunli Shen, MD, PhD, Ming Kuang, MD, PhD

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