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  1. 16321

    Study of the neuroprotective properties of metformin in rats with type 2 diabetes mellitus and brain injury induced by intracerebral hemorrhage by V.L. Holubiev, M.H. Oberemok, V.A. Tkachenko, Yu.V. Kharchenko, O.O. Bondarenko, A.E. Lievykh, V.I. Zhyliuk

    Published 2024-06-01
    “…Type 2 diabetes mellitus (T2DM) was induced in rats via the intraperitoneal injection of streptozotocin (STZ) and nicotinamide (NA), ICH – by microinjection of bacterial collagenase into the striatum. Rats were randomly divided into four groups: 1 – intact animals (n=8), 2 – T2DM (n=9); 3 – T2DM+ICH (n=7); 4 – T2DM+ICH+Met (n=7). …”
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  2. 16322
  3. 16323

    Bayesian Estimation of the True Bovine Brucellosis Prevalence in Vaccinated and Non-Vaccinated Ecuadorian Cattle Populations, and the Sensitivity and Specificity of a Competitive a... by Ana Dolores Garrido Haro, Margoth Yolanda Barrionuevo Samaniego, Paola Moreno-Caballeros, Alexandra Burbano-Enríquez, Verónica Alexandra Salas Torres, María Cristina Galante Mulki, Constance Wielick, Jorge Ron-Román, Claude Saegerman

    Published 2025-01-01
    “…To estimate and compare the diagnostic sensitivity (Se) and specificity (Sp) of two screening tests, a new competitive (cELISA) and an indirect ELISA based on a new synthetic antigen (iELISA), a randomized, stratified, cross-sectional, serological survey was performed on the cattle population (3299 bovine sera from 223 farms) in continental Ecuador. …”
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  4. 16324
  5. 16325

    Gut microbiota, metabolites, and cytokines in relation to the risk of prostate cancer in the Asian population by Zhengshi Wang, Zhengshi Wang, Zhengshi Wang, Zhengshi Wang, Zhengshi Wang, Haotian Chen, Haotian Chen, Yongqiang Liu, Yongqiang Liu, Libin Zou, Libin Zou, Zhijin Zhang, Zhijin Zhang, Zhiqiang Yin, Zhiqiang Yin, Shiyu Mao, Shiyu Mao, Changcheng Guo, Changcheng Guo, Bin Yang, Bin Yang, Pengfei Wu, Pengfei Wu, Pengfei Wu, Xudong Yao, Xudong Yao

    Published 2025-01-01
    “…There were 418 bacterial traits, 452 metabolites, 91 cytokines, 5408 cases of prostate cancer from East Asia, and 109,347 controls included. Mendelian randomization (MR) analyses were performed to investigate their causal relationships. …”
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  6. 16326
  7. 16327

    Longitudinal Screening for Diabetic Retinopathy in a Nationwide Screening Program: Comparing Deep Learning and Human Graders by Jirawut Limwattanayingyong, Variya Nganthavee, Kasem Seresirikachorn, Tassapol Singalavanija, Ngamphol Soonthornworasiri, Varis Ruamviboonsuk, Chetan Rao, Rajiv Raman, Andrzej Grzybowski, Mike Schaekermann, Lily H. Peng, Dale R. Webster, Christopher Semturs, Jonathan Krause, Rory Sayres, Fred Hersch, Richa Tiwari, Yun Liu, Paisan Ruamviboonsuk

    Published 2020-01-01
    “…To evaluate diabetic retinopathy (DR) screening via deep learning (DL) and trained human graders (HG) in a longitudinal cohort, as case spectrum shifts based on treatment referral and new-onset DR. Methods. We randomly selected patients with diabetes screened twice, two years apart within a nationwide screening program. …”
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  8. 16328

    Use of Blood Lipid Indicators as a Screening Tool of Insulin Resistance among Individuals in Low-Income Country Sides of China: A Multiethnic Region Study by Yi-Zhong Yan, Jia-Ning Fan, Jia-Ming Liu, Yun-hua Hu, Jiao-Long Ma, Jia He, Heng Guo, Xiang-hui Zhang, Xin-ping Wang, Shu-gang Li, Shu-Xia Guo

    Published 2019-01-01
    “…Overall, 418 Uygurs, 331 Kazakhs, and 220 Hans were randomly included in our study. The homeostasis model assessment was the gold standard for identifying IR. …”
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  9. 16329

    Canadian Rhinology Working Group consensus statement: biologic therapies for chronic rhinosinusitis by Andrew Thamboo, S. Kilty, I. Witterick, Y. Chan, C. J. Chin, A. Janjua, A. Javer, J. Lee, E. Monterio, B. Rotenberg, J. Scott, K. Smith, D. D. Sommer, L. Sowerby, M. Tewfik, E. Wright, M. Desrosiers

    Published 2021-03-01
    “…There have been eight randomized, double-blind, placebo-controlled trails performed for CRSwNP targeted components of the Type 2 inflammatory pathway, notably interleukin (IL)-4, IL-5 and IL-13, IL-5R, IL-33, and immunoglobulin (Ig)E. …”
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  10. 16330

    Evaluating the efficacy of carbetocin versus oxytocin for preventing intraoperative blood loss, early postpartum hemorrhage, and maintaining a favorable hemodynamic profile in lowe... by Bisma Fayaz, Raja Suhail Shounthoo, Ajaiz Rasool, Saima Wani, Showkat Ahmad Gurcoo

    Published 2025-02-01
    “…Materials and Methods: A total of 360 patients were enrolled for the study, sample size was calculated using Cochran’s formula considering 95% confidence level, and 0.5 variability of proportions and a precision of 5%, with 180 patients in each group, using simple randomization technique, the patients in either group received their assigned drugs during lower segment cesarean section (LSCS). …”
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  11. 16331

    Comparative efficacy and safety of GLP-1 receptor agonists for weight reduction: A model-based meta-analysis of placebo-controlled trials by Haoyang Guo, Juan Yang, Jihan Huang, Ling Xu, Yinghua Lv, Yexuan Wang, Jiyuan Ren, Yulin Feng, Qingshan Zheng, Lujin Li

    Published 2025-03-01
    “…Methods: This systematic review of public databases included placebo-controlled randomized clinical trials of GLP-1RAs. Time-course, dose-response, and covariate models were used to describe the efficacy characteristics and influencing factors of different GLP-1RAs. …”
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  12. 16332

    Severity Assessment of COVID-19 Using a CT-Based Radiomics Model by Zhigao Xu, Lili Zhao, Guoqiang Yang, Ying Ren, Jinlong Wu, Yuwei Xia, Xuhong Yang, Milan Cao, Guojiang Zhang, Taisong Peng, Jiafeng Zhao, Hui Yang, Jinfeng Hu, Jiangfeng Du

    Published 2021-01-01
    “…Meanwhile, they were split randomly to training and test datasets with the fixed ratio of 7 : 3 in each category. …”
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  13. 16333

    Effects of Probiotics Red Yeast Rhodotorula paludigena CM33 on enhancing color pigmentation, antioxidant activity, immune response, intestinal microbiota, and growth in a commercia... by Jirawadee Kaewda, Papungkorn Sangsawad, Surintorn Boonanuntanasarn, Pimpisut Manassila, Apichat Boontawan, Mariena Ketudat‑Cairns, Cheeranan Sriphuttha, Chatsirin Nakharuthai

    Published 2025-03-01
    “…This study evaluated the probiotic properties of red yeast Rhodotorula paludigena CM33 in flowerhorn fish (initial weight 9.81 ± 1.25 g). Forty fish were randomly distributed into individual glass tanks and subjected to four feeding treatments: a non-supplemented control diet and diets supplemented with 0.5 %, 1 %, and 2 % R. paludigena CM33 for 105 days. …”
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  14. 16334

    Sex and race disparities in emergency department patients with chest pain and a detectable or mildly elevated troponin by Lucas M. Boyer, Anna C. Snavely, Jason P. Stopyra, Subha V. Raman, Jeffrey M. Caterino, Carol L. Clark, Alan E. Jones, Michael E. Hall, Carolyn J. Park, Brian C. Hiestand, Sujethra Vasu, Michael A. Kutcher, W. Gregory Hundley, Simon A. Mahler, Chadwick D. Miller

    Published 2025-01-01
    “…Methods: We conducted a secondary analysis of the CMR-IMPACT trial that randomized patients with symptoms suggestive of acute coronary syndrome and a detectable or mildly elevated troponin measure from 4 US hospitals to an early invasive angiography or cardiac MRI strategy. …”
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  15. 16335

    Effectiveness of a nurse-led coaching in self-care intervention for elderly undergoing total laryngectomy: a randomised controlled trial by Yan Liu, Lai Wei, Xue Li, Jian Chen, Huifen Wang, Liyuan Zheng, Shu'e Liu, Danxia Peng, Sanxia Ye, Yuchen Lu, Zhidan Mei, Chun Xu

    Published 2024-12-01
    “…Objectives To evaluate the effectiveness of nurse-led coaching in self-care (SC) interventions for elderly patients undergoing total laryngectomy (TL) using multidimensional parameters.Design This was a double-arm randomised, single-centre trial that met the requirements of the CONSORT statement.Setting Head and neck department in a tertiary A-level hospital.Intervention Elderly patients scheduled for TL were randomly allocated to either the control group (n=24) or the intervention group (n=23). …”
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  16. 16336

    Maternal exposure to deltamethrin during pregnancy and lactation impairs hippocampal learning and memory function of male offspring by ferroptosis by Shasha Huang, Wanqi Li, Dengke Wang, Huiwen Feng, Bo Wang, Xinyu Dong, Wei Zhao, Dan Liu, Yuan Wang

    Published 2025-01-01
    “…In our study, pregnant Wistar rats were randomly divided into four groups and gavaged at doses of 0, 1, 4 or 10 mg/kg/d DM from gestational day (GD) 0 to postnatal day (PND) 21. …”
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  17. 16337

    Emergency Airway Management: A Systematic Review on the Effectiveness of Cognitive Aids in Improving Outcomes and Provider Performance by Raisa Chowdhury, Ostap Orishchak, Marco A. Mascarella, Bshair Aldriweesh, Mohammed K. Alnoury, Guillaume Bousquet-Dion, Jeffrey Yeung, Lily Ha-Nam P. Nguyen

    Published 2025-01-01
    “…<b>Results:</b> Five studies met inclusion criteria, encompassing randomized controlled trials, controlled studies, and mixed-methods research. …”
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  18. 16338

    Adjuvant endocrine therapy with cyclin-dependent kinase 4/6 inhibitor, ribociclib, for localized hormone receptor-positive/HER2– breast cancer (LEADER) by Laura M. Spring, Lauren Scarpetti, Arielle J. Medford, Andrzej Niemierko, Amy Comander, Therese Mulvey, Lowell Schnipper, Steven J. Isakoff, Beverly Moy, Seth A. Wander, Jennifer Shin, Zanta Ephrem, Anneke R. Laposta, Elyssa Denault, Elizabeth Abraham, Gayle Calistro, Ekaterina Kalashnikova, Angel Rodriguez, Minetta C. Liu, Alexey Aleshin, Jeffrey Peppercorn, Leif W. Ellisen, Aditya Bardia

    Published 2025-01-01
    “…Patients with stage I–III hormone receptor-positive (HR+)/HER2– breast cancer on adjuvant endocrine therapy (ET) were randomized to two ribociclib dosing schedules: 400 mg continuous vs 600 mg intermittent, with initiation in early (prior ET < 2 years) vs delayed (prior ET ≥ 2 years) setting. …”
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  19. 16339

    Quantifying the impact of fermented liquid bio formulations, biofertilizers and organic amendments on horticultural and soil nutrient traits of garden pea ( Pisum sativum L.) by Vandana Thakur, Praveen Sharma, Pradeep Kumar, Payal Sharma, Sartaj Ahmad Bhat, Sunny Sharma, Rehan Azmi, Shivender Thakur

    Published 2023-04-01
    “…Method: The present experimentation was carried out to assess the effect of various treatments comprised of fermented liquid bio formulations, biofertilizers, & organic amendments on the horticultural, biochemical, & soil nutrient attributes of garden pea varieties. A Factorial Randomized Block Design was laid out for treatments in three replications.  …”
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  20. 16340

    Donafenib combined with sintilimab for advanced hepatocellular carcinoma: a single arm phase II trial by Xiaoyang Hong, Yongjian Guo, Wenbo Shi, Kangshun Zhu, Licong Liang, Liteng Lin, Ye Chen, Jingwen Zhou, Jingjun Huang, Jiabai Huang, Yaozhu Wu, Wensou Huang, Mingyue Cai

    Published 2025-02-01
    “…The preliminary findings need to be further evaluated in phase III randomized controlled trials. Trial registration ClinicalTrials.gov (identifier: NCT05162352; date of registration: December 4, 2021).…”
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