Neoadjuvant chemoimmunotherapy for locally advanced squamous cell carcinoma of the head and neck: Systematic review and meta-analysis by Xiayi Zhu, Jie Qiu, Ya Zhang, Chunni Lin, Xiaohui Wang, Xiwei Shi, Siya Yang, Qiaoyan Wu, Li Cong

“…Conclusion: Neoadjuvant chemoimmunotherapy has shown promising efficacy and safety for LA-SCCHN, but further randomized trials are needed to confirm long-term survival benefits.…”
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The relationship between thiamin, folic acid and cognitive function in a rat model of uremia by Yifei Lu, Chenqi Xu, Kewei Xie, Bingru Zhao, Minzhou Wang, Cheng Qian, Xuemei Chen, Leyi Gu, Wangshu Wu, Renhua Lu

“…Therefore, 24 Sprague-Dawley rats were randomly divided into two groups: a 5/6 nephrectomy group (n = 12) and a sham-operated group (n = 12). …”
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Effect of Different Types of Mulching on Soil Properties and Tree Growth of Magnolia champaca Planted at the Montane Rainforest in Cameron Highlands, Pahang, Malaysia by Wahidullah Rahmani, Mohd Nazre Salleh, Mohd Zaki Hamzah, Aminu Abdu, Mohamad Fakhri Ishak, Wan Rasidah Wan Abd Khadir, Mohd Ridza Awang, Zahari Ibrahim, Ahmad Fadzil Abd Majid, Mohd Shahrir Azrin Salleh, Azhar Anuar, Mohamad Azani Bin Alias

“…In this study, we used a randomized complete block design (RCBD) and measured the Magnolia champaca height, root collar diameter, diameter at breast height, plant survival, root diameter, main root length, lateral root length, root coiling, root direction, and chlorophyll content. …”
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Concentrated growth factors promote epithelization in the mastoid obliteration after canal wall down mastoidectomy by Mengyi Liu, Lue Zhang, Quanming Zhang, Nan Zeng, Shuo Li, Shuyue Guo, Yaqin Zhao, Mingxing Tang, Qiong Yang

“…Conclusion: The application of CGF to surgical cavity obliteration following a CWD mastoidectomy significantly promotes epithelialization, thereby achieving satisfactory results. Randomized controlled trials with a larger number of patients enrolled were worth launching in the future to better substantiate the value of CGF in obliteration of mastoid cavity. …”
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Computerised cognitive training tools and online nutritional group counselling for people with mild cognitive impairment: study protocol of a completely digital, randomised, contro... by Stephanie Book, Elmar Graessel, Julia Schneider, Michael Jeitler, Petra Scheerbaum, Michael Jank, Etienne Hanslian, Melanie DellO’ro, Julia-Sophia Scheuermann, Sophia Bösl, Christian Kessler

“…Participants will be randomly allocated to one of four groups and will receive a combination of CCT and online nutritional counselling. …”
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Cognitive behavioural therapy plus Kiesler Circle Training (CBT+) versus CBT only for patients with interpersonal problems: study protocol for a randomised controlled feasibility t... by Stephan Köhler, Philipp Sterzer, Eva-Lotta Brakemeier, Karen Ollrogge, Daniel Schulze, Eva Friedel, Nina Romanczuk-Seiferth, Anna-Lena Siegerist, Anne Guhn

“…All patients will receive individual, state-of-the-art cognitive behavioural therapy (CBT) during the study. They will be randomly assigned to one of two conditions: the experimental group will receive the KCT in group sessions, in addition to individual CBT, while the control group will receive only individual CBT. …”
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Cellular EMT-status governs contact guidance in an electrospun TACS-mimicking in vitro model by Lorenz Isert, Mehak Passi, Benedikt Freystetter, Maximilian Grab, Andreas Roidl, Christoph Müller, Aditi Mehta, Harini G. Sundararaghavan, Stefan Zahler, Olivia M. Merkel

“…By employing a rotating cylinder or static plate collector set-up, aligned fibers (TACS5-like structures) and randomly orientated fibers (TACS6-like structures) fibers were produced, respectively. …”
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Evaluation of parent reminder-recall letters to promote human papillomavirus vaccination by Joan M. Griffin, Xuan Zhu, Wei Yi Kong, Robert M. Jacobson, Kathy L. MacLaughlin, Jennifer L. St. Sauver, Jeph Herrin, Gregory D. Jenkins, Nicole L. Larson, Lila J. Finney Rutten

“…Our stepped-wedge cluster randomized trial found that reminder-recall letters sent to parents of age-eligible children significantly increased vaccine uptake compared to usual care. …”
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Stability, performance and participatory evaluation of potato varieties under rain-fed and irrigation conditions at Southeast, Ethiopia by Gizaw Wegayehu Tilahun, Nimona Fufa, Dasta Tsagaye, Demis Fikre, Awoke Ali, Fekadu Gebretensay, Kedir Jaleto

“…The objective of this study was to evaluate the performance and stability of potato varieties linking the preferences of smallholder farmers in rain-fed and irrigated environments. Using a randomized complete block design in three replicates, twelve potato cultivars were assessed in 10 settings in Southeast Ethiopia during the Meher and Belg seasons in 2019 and 2020. …”
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Application of stem cells alone and in combination with low-level laser therapy for sciatic nerve repair in rats by Mohsen Shalalvand, Hamidreza Mahaseni Aghdam, Ahmad Asghari, Siamak Nehzat, Fatemeh Shahsavari, Rojin Ardalani

“…In this animal study, the right sciatic nerve of 30 male Wistar rats, each weighing 250–300 g, was surgically excised to a length of 8 mm. The rats were then randomly allocated to three groups (n = 10 per group). …”
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Comparison of Non-Contrast CT vs. Contrast-Enhanced CT with Both Intravenous and Rectal Contrast Application for Diagnosis of Acute Colonic Diverticulitis: A Multireader, Retrospec... by Dorottya Móré, Stella Erdmann, Arved Bischoff, Verena Wagner, Hans-Ulrich Kauczor, Lukas F. Liesenfeld, Katharina Abbasi Dezfouli, Athanasios Giannakis, Miriam Klauß, Philipp Mayer

“…<b>Methods</b>: Five readers retrospectively evaluated the non-contrast and contrast-enhanced series of CTs of 205 consecutive patients with clinical suspicion of acute diverticulitis. Two randomized reading sessions, both containing all 205 cases as either contrast-enhanced or non-contrast (1:1) series, were performed with ≥8 weeks washout between them. …”
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An in vitro study on comparative evaluation of shear bond strength of bioactive composite to tooth structure with various dentin conditioning agents by Priyanka Pokkula, Shaik Mohammed Asif, Abdullah Alqarni, Shahabe Saquib Abullais, Shaik Mohamed Shamsudeen, Syed M Yassin, Abosofyan S. Atta, Wahaj Ahmad Khan

“…Sixty extracted human maxillary premolars were collected for this study. They were randomly divided into four groups. They were treated with their respective conditioning and bonding agents. …”
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Tumor aggression-defense index–a novel indicator to predicts recurrence and survival in stage II-III colorectal cancer by Tong Wu, Lin Fang, Yuli Ruan, Mengde Shi, Dan Su, Yue Ma, Ming Ma, Bojun Wang, Yuanyu Liao, Shuling Han, Xiaolin Lu, Chunhui Zhang, Chao Liu, Yanqiao Zhang

“…Methods This retrospective study analyzed 1051 pMMR CRC patients who underwent radical resection and were randomly assigned to training (n = 736) and validation (n = 315) groups. …”
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Abdominal fat distribution and its relationship to brain changes: the differential effects of age on cerebellar structure and function: a cross-sectional, exploratory study by Yvonne Böttcher, Michael Stumvoll, Kees Straatman, Matthias Raschpichler, Matthias Leopold Schroeter, Katrin Arelin, Haiko Schlögl, Dominik Fritzsch, Meinhard Mende, André Pampel, Arno Villringer, Karsten Mueller

“…Moreover, we aimed to investigate whether these effects change with age.Design Cross-sectional, exploratory.Setting University Clinic, Integrative Research and Treatment Centre.Participants We included 100 (mean BMI=26.0 kg/m², 42 women) out of 202 volunteers randomly invited by the city's registration office, subdivided into two age groups: young-to-mid-age (n=51, 20–45 years of age, mean BMI=24.9, 24 women) versus old (n=49, 65–70 years of age, mean BMI=27.0, 18 women).Main outcome measures VAT, BMI, subcutaneous abdominal adipose tissue, brain structure (grey matter density), functional brain architecture (eigenvector centrality, EC).Results We discovered a loss of cerebellar structure with increasing VAT in the younger participants, most significantly in regions involved in motor processing. …”
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Long-Term Results After Laparoscopic Lavage for Perforated Diverticulitis Purulent Peritonitis in Sweden: A Population-Based Observational Study by Andreas Samuelsson, MD, David Bock, PhD, Mattias Prytz, MD, PhD, Carolina Ehrencrona, BSc, Anette Wedin, RN, Eva Angenete, MD, PhD, Eva Haglind, MD, PhD

“…Laparoscopic lavage has been studied in 3 randomized controlled trials. Long-term results indicate that additional surgery and a remaining stoma are less common after lavage compared with resection, but data from routine care and larger cohorts are needed to get a more complete picture. …”
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Genetic variability and heritability estimates among nutritional traits of groundnut breeding lines by Richard Adu Amoah, James Yaw Asibuo, Richard Akromah, Kwabena Asare Bediako, Maxwell Lamptey, Collins Yeboah Osei, Samuel Awuah, Richard Boampong

“…The trial consisted of 12 advance breeding lines and 7 varieties which were evaluated in a randomized complete block design (RCBD) in three (3) replications at CSIR-Crop Research Institute, Fumesua, Ghana. …”
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Value of Magnifying Chromoendoscopy and Magnifying Optical Enhancement Technology in Classifying Colorectal Polyps: A Prospective Controlled Study by Ying-Hao Song, Ruo-Xin Xu, Yong Zhang, Meng-Xuan Xing, Li-Dong Xu, Kun-Kun Li, Xing-Guo Xiao, Lu Li, Yan-Jing Xiao, Yu-Lei Qu, Ying-Jie Ma, Bao-Hui Jia, Hui-Li Wu

“…Consecutive patients undergoing colonoscopy were randomized (1 : 1) into examination by ME-OE or ME-CE. …”
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Effects of a foot-ankle strengthening programme on clinical aspects and gait biomechanics in people with knee osteoarthritis: protocol for a randomised controlled trial by Tania F Salvini, Glauko Dantas, Isabel C N Sacco, Ana F dos Santos, Ricky Watari, Alessandra B Matias, Paula R M S Serrao, Henrique Pott-Junior

“…The aim of this paper is to investigate whether an 8-week therapeutic foot-ankle exercise programme improves pain, functionality, foot strength, foot kinematics and knee joint overload during gait, and decreases medication intake in individuals with KOA.Methods and analysis This two-arm, prospectively registered, randomised controlled trial with blinded assessors will involve 88 patients with medial tibiofemoral osteoarthritis. Subjects will be randomly allocated to a control group that will receive no specific foot intervention and will follow treatment recommended by the medical team; or an intervention group that will undergo an 8-week physiotherapist-supervised strengthening programme for extrinsic and intrinsic foot muscles, three times a week. …”
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Development and validation of a prognostic nomogram incorporating neutrophil-to-albumin ratio for predicting overall survival in patients with nasopharyngeal carcinoma undergoing c... by Xin Hua, Meng-Di Wang, Wei-Qiong Ni, Zhi-Qing Long, Si-Fen Wang, Fang-Fang Duan, Chao Zhang, Xin Huang, Fei Xu, Wen Xia, Jia-Yi Chen, Yun-Sheng Gao

“…Methods: This retrospective analysis included 861 NPC patients treated with concurrent chemoradiotherapy (CCRT), who were randomly divided into a training group (n = 605) and a validation group (n = 256). …”
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The multiple uses of artificial intelligence in exercise programs: a narrative review by Alberto Canzone, Alberto Canzone, Giacomo Belmonte, Antonino Patti, Domenico Savio Salvatore Vicari, Domenico Savio Salvatore Vicari, Fabio Rapisarda, Valerio Giustino, Patrik Drid, Antonino Bianco

“…Machine learning, a subset of artificial intelligence, concentrates on empowering computers to learn and enhance from data autonomously; this narrative review seeks to elucidate the utilization of artificial intelligence in fostering physical activity, training, exercise, and health outcomes, addressing a significant gap in the comprehension of practical applications.MethodsOnly Randomized Controlled Trials (RCTs) published in English were included. …”
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