NAFPD exacerbation by hyperlipidemia combined with hyperuricemia: a pilot rat experiment in lipidomics by Jingyun Li, Jingyun Li, Yongjian Chen, Shilin Li, Guorong Lyu, Guorong Lyu, Furong Yan, Jiajing Guo, Jing Cheng, Yun Chen, Jiaojiao Lin, Yating Zeng

“…BackgroundHyperuricemia and non-alcoholic fatty pancreas disease (NAFPD) are prevalent metabolic diseases, but the relationship between them remains underexplored.MethodsEighteen Sprague–Dawley rats were randomly assigned to three groups: normal (CON), high-fat (PO), and high-fat high-uric acid (PH). …”
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Acanthopanax versus 3-Methyladenine Ameliorates Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting the Autophagic Pathway in Rats by Xiaohong Wang, Guoxiong Zhou, Chun Liu, Ronglong Wei, Shunxing Zhu, Yuefen Xu, Mengjie Wu, Qing Miao

“…Sodium taurocholate-induced SAP rats were equally randomized into a SAP group, an Acanthopanax group, and a 3-methyladenine group. …”
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Sustained immunogenicity of bivalent protein COVID-19 vaccine SCTV01C against antigen matched and mismatched variants by Guiqiang Wang, Kexin Zhao, Xiuli Zhao, Yimin Cui, Peng He, Tianzuo Zhang, Yanchao Wang, Rui Shi, Yanhua Li, Qian Wang, Yanping Ren, Zhisong Chen, Xuedan Zhao, Zekang Xie, Yufei Liang, Qingyun Tian, Jing Pan, Chao Zhang, Ying Han, Yuyang Dai, Siyang Ni, Yun Zhang, Xinjie Yang, Yongpan Fu, Dongfang Liu, Jing Li, Miaomiao Zhang, Zhongyu Hu, Liangzhi Xie

“…Background The development of bivalent or multivalent vaccines offers a promising strategy for combating SARS-CoV-2 mutations.Research design and methods In this phase 2 trial, conducted from 1 December 2021, to 25 July 2023, 392 unvaccinated adults aged ≥18 years were randomized to receive a primary series of two doses and a booster dose of SCTV01C, a bivalent protein SARS-CoV-2 vaccine.Results Geometric mean titers (GMTs) of neutralizing antibodies (nAb) against live Alpha, Beta, Delta, and Omicron showed 85.4-, 100.0-, 32.1-, and 9.8-fold increase from baseline on 28 days, and 49.4-, 55.3-, 5.7-fold increase against live Alpha, Beta, and Omicron on 90 days after primary series. …”
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Effectiveness of Space Maintainers in Pediatric Patients: A Systematic Review and Meta-Analysis by MDolores Casaña-Ruiz, Juan Ignacio Aura-Tormos, Laura Marques-Martinez, Esther Garcia-Miralles, Marcelino Perez-Bermejo

“…<b>Results:</b> The total number of patients treated in the studies was 479, with four observational studies and seven randomized clinical trials. Fixed space maintainers, such as band and loop (BL) or lingual arch (LA), are preferred due to their long-term stability and lower risk of loss. …”
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Effects of Tert-Butylhydroquinone on Intestinal Inflammatory Response and Apoptosis following Traumatic Brain Injury in Mice by Wei Jin, Hongbin Ni, Yuxiang Dai, Handong Wang, Tianyu Lu, Jun Wu, Jian Jiang, Weibang Liang

“…Adult male ICR mice were randomly divided into three groups: (1) sham + vehicle group, (2) TBI + vehicle group, and (3) TBI + tBHQ group (n=12 per group). …”
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A Novel Role of Globular Adiponectin in Treatment with HFD/STZ Induced T2DM Combined with NAFLD Rats by Hong Ma, Guo-Ping You, Xuan-Pu Zhang, Xiang-Jiu Yang, Hua-Dong Lu, Yan-Ling Huang, Wen-Qiang Zhang

“…Half of T2DM rats were randomly injected with gAd intraperitoneally for 7 days. …”
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Dietary inclusion of Moringa oleifera leaf extracts as alternatives to antibiotic growth promoter on live performance, carcass traits, physical meat quality, and health status of b... by Al Ibne Rifat, Chondhon Chandro Bormon, Md Golam Akib, Mohammad Shamsul Ataher, Md Kamruzzaman, Amitush Dutta, Amio Kante Das, Kanan Talukder, Mahmoud Azzam, Mohammed Hamdy Farouk, Razib Das, Shad Mahfuz

“…A total of 144 Arbour Acres broilers were randomly assigned into 3 experimental groups (eight replicates having six chicks), naming control (received a basal diet with fresh drinking water), antibiotic (75 mg chlortetracycline/L of drinking water), and MLE (50 ml Moringa oleifera leaf extracts/L of drinking water). …”
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Efficacy of unified protocol for transdiagnostic treatment of emotional disorders in adolescents (UP-A) in China: protocol for a randomised controlled trial by Xue Gao, Lu Liu, Mei-Rong Pan, Hai-Mei Li, Yu-Feng Wang, Xue-Ying Liu, Zhong-Fang Fu, Qiujin Qian

“…Forty-eight participants will be randomly assigned to either the treatment as usual (TAU) group or the TAU combined with UP-A (UP-A+TAU) group. …”
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Combined therapy of human amnion-derived mesenchymal stem cells and scalp acupuncture alleviates brain damage in a rat model of cerebral palsy by Yu Zhou, Xu-Huan Li, Lu-Na He, Li-Na Wang, Jing Zang, Dong-Ming Wang, Jing Gao, Xue-feng Yu

“…Methods: Twenty male Sprague-Dawley rats were randomly divided into four groups: Sham, CP, hAMSCs, and hAMSCs+scalp acupuncture (hAMSCs+AP). …”
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Exploring the relationship between mental health status and life events in children and adolescents: the role of mediating factors by Jiemei Xie, Jiemei Xie, Guoqiang Cheng, Mingliang Zhou, Qisheng Liang, Qianjin Wang, Qianjin Wang, Qianjin Wang

“…This study aims to examine the relationship between negative life events and symptoms of anxiety and depression in children and adolescents, as well as to identify potential mediating factors.MethodsIn May 2022, cluster-randomized sampling was used to select 8041 primary, middle, and high school students in Zhaoqing City, Guangdong Province, for the final analysis. …”
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Low-Frequency Repetitive Transcranial Magnetic Stimulation for Stroke-Induced Upper Limb Motor Deficit: A Meta-Analysis by Lan Zhang, Guoqiang Xing, Shiquan Shuai, Zhiwei Guo, Huaping Chen, Morgan A. McClure, Xiaojuan Chen, Qiwen Mu

“…Databases of PubMed, Medline, ScienceDirect, Cochrane, and Embase were searched for randomized controlled trials published before Jun 31, 2017. …”
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EVALUATION OF POPULATION-LEVEL IMMUNITY TO SARS-COV-2 ACROSS BULGARIA (END OF 2023) by Kim Ngoc, Iva Trifonova, Teodora Gladnishka, Elitsa Panayotova, Evgenia Taseva, Vladislava Ivanova, Eleonora Kutevа, Iva Vladimirova, Iva Christova

“…Materials and methods: In December 2023, 1895 serum samples were randomly collected from healthy individuals across all 28 provinces. …”
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The Peroxisome Proliferator-Activated Receptor γ Agonist Pioglitazone Protects Vascular Endothelial Function in Hypercholesterolemic Rats by Inhibiting Myeloperoxidase by Dapeng Zhang, Yehong Wang, Ming Yi, Suli Zhang, Ye Wu

“…Male Wistar rats were fed with normal or high cholesterol diets for 8 weeks. HC rats were randomized to receive dapsone (DDS, the MPO inhibitor) during the last 6 days or PIO for the remaining 4 weeks. …”
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Influence of Immediate Dentin Sealing on the Shear Bond Strength of Pressed Ceramic Luted to Dentin with Self-Etch Resin Cement by Robert Dalby, Ayman Ellakwa, Brian Millar, F. Elizabeth Martin

“…Eighty extracted noncarious third molars were ground flat to expose the occlusal dentin surfaces. The teeth were randomly allocated to five groups (A to E) of sixteen teeth each. …”
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The potential of fungi-bacterial biofilm, compost, and LOF compared with chemical fertilization in supporting the growth of pakcoi (Brassica rapa var chinensis) by Rosariastuti Retno, Rosada Hanifati, Sutami, Irawan Evi, Nugraha Setyo, Simamarta Rumella, Haryuni

“…This study used a three-factor (fertilizer type, inorganic fertilizer doses, and organic fertilizer doses) with a Complete Group Randomized Design with 14 treatments (N0: Control, N1: 100 % NPK + 0 Organic fertilizer, NB 2: 75% NPK + 25% BFBF, NB 3: 50% NPK + 50% BFBF, NB 4: 25 % NPK + 75% BFBF, NB 5: 0% NPK + 100% BFBF, NP 2: 75% NPK + 25% LOF, NP 3: 50% NPK + 50% LOF, NP 4: 25 % NPK + 75% LOF, NP 5: 0 NPK + 100 % LOF, NR 2: 75% NPK + 25% Compost, NR 3: 50% NPK + 50% Compost, NR 4: 25 % NPK + 75% Compost, NR 5: 0% NPK + 100% Compost). …”
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A Nomogram for Predicting Overall Survival in Primary Central Nervous System Lymphoma: A Retrospective Study by Ling Y, Miao X, Zhou X, Ma J, Lin Z, Li Q, Zhang M, Ma Y, Chen B

“…This study aimed to develop a novel prognostic model based on real clinical data and compare it with existing systems.Patients and Methods: A total of 288 patients newly diagnosed with PCNSL were recruited. Patients were randomly allocated to the development and validation cohorts. …”
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Arsenic Uptake in Durum Wheat (<i>Triticum durum</i> Desf.) as Influenced by Soil Tillage Practices and Fertilization Sources in Mediterranean Environment by Ilenia Bravo, Mariam Atait, Ilenia Colamatteo, Roberto Mancinelli, Mohamed Allam, Patrizia Papetti, Emanuele Radicetti

“…The experimental treatments include the following: (i) three soil tillage practices (plowing, subsoiling, and spading) and (ii) two fertilization methods (mineral and organic). A factorial randomized complete block design with three replications was adopted. …”
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Integrated chronic care models for people with comorbid of HIV and non-communicable diseases in Sub-Saharan Africa: A scoping review. by Rumbidzai Chireshe, Tawanda Manyangadze, Keshena Naidoo

“…Data on some short-term benefits of integrated care was available, but evidence was absent on the long-term outcomes. Randomized clinical trials with clearly defined comparator groups and standardized measures of HIV and NCD outcomes are needed to demonstrate non-inferiority of integrated against non-integrated care.…”
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Comparative Effectiveness of Anti-Inflammatory Drug Treatments in Coronary Heart Disease Patients: A Systematic Review and Network Meta-Analysis by Ivan Wudexi, Elica Shokri, Mohamed Abo-Aly, Kazuhiro Shindo, Ahmed Abdel-Latif

“…We conducted a network meta-analysis of randomized controlled trials that studied the effects of anti-inflammatory medications on cardiovascular outcomes of coronary artery disease patients. …”
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Optimising patient engagement for assessing total joint arthroplasty outcomes – a randomised controlled trial by Wyatt Tyndall, Nebojsa Kuljic, Michael Thatcher, Michaela Nickol, Johannes M. van der Merwe

“…To improve response rates, this study evaluated various methods of incentivizing patient participation in a randomized trial format, focusing on postal questionnaires. …”
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