Transcutaneous Electrical Nerve Stimulation Integrated into Pants for the Relief of Postoperative Pain in Hip Surgery Patients: A Randomized Trial by Yohann Opolka, Courage Sundberg, Robin Juthberg, Amelie Olesen, Li Guo, Nils-Krister Persson, Paul W. Ackermann

“…The effect of transcutaneous electrical nerve stimulation (TENS) on pain and impression of change was assessed during a 2.5-hour intervention on the first postoperative days following hip surgery in a randomized, single-blinded, placebo-controlled trial involving 30 patients. …”
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Randomized controlled trial comparing quadratus Lumborum Block and Surgical Site Infiltration in Total Abdominal Hysterectomy: Efficacy Analysis by Sangeeta Dhanger, R L Jayavani, Bhavani Vaidiyanathan, Idhuyya Joseph Rajesh

“…This study aimed to compare the efficacy of the quadratus lumborum block (QLB) with surgical site infiltration (SSI) in managing postoperative pain following total abdominal hysterectomy. Methods: In a randomized controlled trial, 60 female patients scheduled for total abdominal hysterectomy under spinal anesthesia were divided into two groups: QLB and SSI, with 30 patients in each group. …”
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Exploring the causal associations between immunoglobulin G N-glycosylation and chronic spinal pain: A Mendelian Randomization study by Zhengqiang Liu, Jun Li, Yuquan Chen, Yiwei Chen

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The effects of playing digital games on children’s pain, fear, and anxiety levels during suturing: A randomized controlled study by Muhammet Kavlakci, Filiz Ogce, Tulay Yavan

“…METHODS: Data were obtained from 84 children between the ages of 8 and 17 years at the pediatric emergency department between January 16 and March 19, 2020, using the Socio-Demographic and Clinical Characteristics Form, the Wong–Baker Faces Pain Rating Scale (WBFPS), the Visual Analogue Scale (VAS), the Fear of Medical Procedures Scale (FMPS), and the State-Trait Anxiety Inventory for Children (STAI-CH). A four-block randomization system was used. The study group (n = 42) played digital games during the suturing procedure, unlike the control group (n = 42). …”
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Causal associations of Helicobacter pylori infection and metabolic syndrome: insights from a two-sample Mendelian randomization study by Hongwei Wang, Fangying Tian, Caizheng Yang, Xinyu Cui, Yongxia Ding, Ming Zhao, Xueyu Wang, Shanshan Ge

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Comparison of Ziziphus jujube Mill. Syrup versus polyethylene glycol in children with functional constipation: a randomized clinical trial by Fatemeh Keihanian, Shohreh Maleknejad, Amin Saeidinia, Soheil Soltanipour, Amir Pirooz

“…Eligible patients were randomized into two groups: PEG group; 1–5 cc/kg/day (40% w/v solution without electrolytes; average dose: 0.2–1 g/kg), and ZS group; 1–5 cc/kg/day (average dose: 5–25 mg/kg). …”
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Comparison of diaphragmatic breathing exercises and incentive spirometry on the functional status of heart failure patients: a randomized controlled trial by Amirhossein Nasirmoghadas, Fateme Monjazebi, Malihe Nasiri, Aydin Feyzi, Fariba Borhani

“…Methods A three-arm single-blind randomized controlled trial was conducted on 90 hospitalized HF patients in three 30-participant groups including diaphragmatic breathing group (DG), incentive spirometry group (SG), and control group (CG). …”
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Six weeks that changed the preterm infant brain: lessons learned from the Family Nurture Intervention randomized controlled trials by Robert J. Ludwig, Robert J. Ludwig, Michael M. Myers, Michael M. Myers, Martha G. Welch, Martha G. Welch

“…AimWe review extensive results from two randomized controlled trials conducted over 9 years, comparing standard care (SC) in level-4 neonatal intensive care units (NICUs) with SC plus Family Nurture Intervention (FNI).MethodsFNI included ~six weeks of facilitated mother-infant interactions aimed at achieving mother-infant ‘autonomic emotional connection’, a novel construct that describes the emotional mother-baby relationship at the level of the autonomic nervous system.Results and conclusionThus far, 18 peer-reviewed publications documented significant positive short-and long-term effects of FNI on infant neurobehavioral functioning, developmental trajectories and both mother and child autonomic health through five years. …”
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Improving reading competence in aphasia with combined aerobic exercise and phono-motor treatment: Protocol for a randomized controlled trial by Olga Boukrina, Elizabeth B. Madden, Brian M. Sandroff, Xiangqin Cui, Abubakar Yamin, Yekyung Kong, William W. Graves

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Investigating the causal effects of childhood and adulthood adiposity on later life mental health outcome: a Mendelian randomization study by Sweta Pathak, Tom G. Richardson, Eleanor Sanderson, Bjørn Olav Åsvold, Laxmi Bhatta, Ben M. Brumpton

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Comparative Efficacy of Antihypertensive Agents in Flow-Mediated Vasodilation of Patients with Hypertension: Network Meta-Analysis of Randomized Controlled Trial by Hong Ding, Shu Liu, Ke-Xin Zhao, Jie Pu, Ya-Fei Xie, Xiao-Wei Zhang

“…Two reviewers independently reviewed and filtered the literature and extracted the data; the Cochrane “risk of bias” method was used to evaluate the methodological quality of the randomized controlled trials. A network meta-analysis was performed using Stata 15.0 software with a total of 49 studies. …”
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Zinc Acetate Hydrate Supplementation versus Polaprezinc Supplementation for Improving Hypozincemia in Hemodialysis Patients: A Randomized Clinical Trial by Etsuko Kumagai, Kazuhiro Furumachi, Akihiro Kurihara, Ken Hosokawa, Keiko Hosohata, Shinji Takai

“…We enrolled 75 hemodialysis patients with serum zinc levels <60 μg/dL for this study and randomly assigned Zinc supplementation to these 75 patients: 37 received ZAH (50 mg/day), and 38 received PPZ (34 mg/day). …”
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Effects of home-based virtual reality upper extremity rehabilitation in persons with chronic stroke: a randomized controlled trial by Hiroyuki Ase, Kaoru Honaga, Mami Tani, Tomokazu Takakura, Futoshi Wada, Yuhei Murakami, Reina Isayama, Akira Tanuma, Toshiyuki Fujiwara

“…Methods This was a single-blind, randomized, controlled trial conducted at two centers. …”
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Comment on “Total Pancreatectomy With Islet Autotransplantation as an Alternative to High-Risk Pancreatojejunostomy After Pancreaticoduodenectomy: A Prospective Randomized Trial” by Leo Buhler, MD, Ty Dunn, MD, Ugo Boggi, MD, Charles Vollmer, MD, Jens Werner, MD, Christos Dervenis, MD, Giovanni Marchegiani, MD, Shailesh V. Shrikhande, MD, Igor Khatkov, MD, Abraham Fingerhut, MD

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First-time use of electronic patient-reported outcome measures in a cluster randomized trial: a qualitative study by Terese Solvoll Skåre, Tonje Lundeby, Jo Åsmund Lund, Marianne Jensen Hjermstad, May Helen Midtbust

“…This study aimed to explore the facilitators and barriers encountered by principal investigators (PIs) (oncologists) and study nurses during the implementation of the Eir ePROM within a cluster randomized trial (c-RCT) in cancer outpatient clinics. …”
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Effect of Nebulized Morphine on Dyspnea of Mustard Gas-Exposed Patients: A Double-Blind Randomized Clinical Trial Study by Majid Shohrati, Mostafa Ghanei, Asghar Amini Harandi, Soniya Foroghi, Ali Amini Harandi

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Comparison of the Effects of Vitagnus, Soy, and Vitagnus-soy Capsules on Premenstrual Syndrome in University Students: A Randomized Clinical Trial by Roya Partovi Golshan, Maryam Moradi, Hasan Rakhshandeh, Vahid Ghavami, Seyed Mostafa Moshirian Farahi

“…Eligible participants diagnosed with moderate to severe PMS over two menstrual cycles, using the Calendar of Premenstrual Experiences form, were randomly assigned to one of three groups. Each participant took one daily capsule of Vitagnus (N=36), Soy (N=36), or a Vitagnus-soy combination (N=36) for two menstrual cycles. …”
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Effect of Genicular Nerve Block (GNB) on Pain in Lesions of the Knee Joint: A Meta-Analysis of Randomized Controlled Trials by Li W, Xu F, Chen F, Cao L, Bao X

“…Computerized searches of randomized controlled trials were conducted in PubMed, EMbase, Cochrane Library, and Web of Science, with a search time frame until January 2024. …”
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Role of Melatonin as an Adjunctive Treatment for Depression and Cognitive Impairment in Hemodialysis Patients: A Randomized, Double-Blind Clinical Trial by Shima Hatamkhani, Sepideh Roshan, Afshin Shiva

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Clinical Effectiveness of Pit and Fissure Sealants Using Solvents for Improving Surface Wettability of Enamel: A Randomized Controlled Trial by Anshula N Deshpande, Pooja V Bane, Simron Baishya, Yash Shah, Sneha Dori

“…Subjects and Methods: Children and adolescents with clinically healthy occlusal surfaces or noncavitated occlusal carious lesions on permanent first and/or second molars in all four quadrants were randomly allocated into four groups. A total population of 87 participants (348 teeth) were selected for the research based on the inclusion criteria. …”
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