Rehabilitation of human hearing with a totally implantable cochlear implant: a feasibility study by Philippe Pierre Lefebvre, Joachim Müller, Gerhard Mark, Florian Schwarze, Ingeborg Hochmair

“…Methods This study used a design with non-randomized single group assignment (trial registration: NCT04571333). …”
Get full text

Effect of Nape Acupuncture Combined with Swallowing Training on Dysphagia in Patients with Parkinson's Disease by Linjing WANG, Xue WANG, Jiyao ZHANG, Jiashuai LI, Xinlei HOU, Luwen ZHU

“…Objective:To explore the effect of acupuncture combined with swallowing training in patients with Parkinson's disease with swallowing dysfunction.Methods:From August 2017 to August 2019, a total of 120 patients with Parkinson's dysphagia with gradesⅡtoⅣof the"Kubota Water Swallowing Test"were selected and randomly divided into treatment group (<italic>n</italic>=60) and control group (<italic>n</italic>=60). …”
Get full text

The Prevalence of Hypertension and Associated Risk Factors among Secondary School Teachers in Bahir Dar City Administration, Northwest Ethiopia by Destaw Damtie, Ayehu Bereket, Denekew Bitew, Bizuayehu Kerisew

“…Two hundred twenty-two randomly selected teachers were interviewed, and data related to the demographic, behavioral, health, and dietary characteristics of the individuals were recorded. …”
Get full text

Tobacco prevalence among adults in the urban slums of Delhi: results from a cross-sectional survey by Shyam Kanhaiya Saroj, Tushti Bhardwaj, Archana Kaushik

“…To ensure a representative sample, 20% of households were randomly selected from each slum. The survey utilized a pre-designed, pretested, and semi-structured questionnaire to collect relevant data. …”
Get full text

Measuring the Impact of COVID-19 on Young Adult Functional Capacity: A Comparative Study of Walking and Step Endurance Tests by Patchareeya Amput, Arunrat Srithawong, Sinthuporn Maharan, Puttipong Poncumhak, Patcharin Phrompao, Eakarach Wongsaya, Tichanon Promsrisuk, Sahachat Aueyingsak

“…Muscle strength (grip and quadriceps strength) was assessed, and functional capacity was evaluated using the 6MWT and 2MST, with the test order randomized by drawing lots. Hemodynamic responses, fatigue, and dyspnea were measured before and after both tests. …”
Get full text

The Effect of High Levels Carbohydrate on Intestinal Microbiota, Metabolites, and Health of Common Carp (Cyprinus carpio L.) by Jinrui Xiong, Liping Yang, Luming Wang, Shaoyang Zhi, Mengjuan Zhao, Chunchu Xu, Leya Qu, Xiaorui Guo, Xiao Yan, Chaobin Qin, Guoxing Nie

“…Two hundred seventy common carps were chosen and distributed randomly into three groups that fed diets containing starch at levels of 15% (low-carbohydrate diet [LCD]), 28% (medium-carbohydrate diet [MCD]), and 45% (high-carbohydrate diet [HCD]) for 60 days. …”
Get full text

Characteristics of Wet Noodles From Sago and Sweet Potato Starch with Mung Bean Flour Substitution by Shanti Fitriani, Yusmarini Yusmarini, Emma Riftyan, Yossie Kharisma Dewi, Ririn Puji Lestari, Tiyah Fadhilah

“…The research was conducted experimentally using a completely randomized design with ten treatments and four replicates. …”
Get full text

Cost-effectiveness analysis of deep brain stimulation for the treatment of alcohol use disorder and alcoholic liver disease by Oluwatofunmi A. Abiola, Collin M. Lehmann, Khaled Moussawi, Hawre Jalal

“…Conclusion: Should it prove efficacious, DBS may be cost-effective for patients with AUD and ALD. Thus, future randomized controlled trials to evaluate its efficacy are warranted.…”
Get full text

An In Situ Evaluation of the Protective Effect of Nano Eggshell/Titanium Dioxide against Erosive Acids by Stanley Chibuzor Onwubu, Phumlane Selby Mdluli, Shenuka Singh, Sanele Nyembe, Rookmoney Thakur

“…Twenty prepared bovine tooth enamel specimens were randomly assigned to 5 sample groups (n=4): (1) unexposed tooth enamel; (2) exposed tooth enamel + HCI; (3) exposed tooth enamel + HCI + Colgate toothpaste; (4) exposed tooth enamel + HCI + Sensodyne toothpaste; and (5) exposed tooth enamel + HCI + EB@TiO2. …”
Get full text

Characterization of Pathogenic Bacteria Isolated from Sudanese Banknotes and Determination of Their Resistance Profile by Noha Ahmed Abd Alfadil, Malik Suliman Mohamed, Manal M. Ali, El Amin Ibrahim El Nima

“…This study was carried out using 135 samples of Sudanese banknotes of five different denominations (2, 5, 10, 20, and 50 Sudanese pounds), which were collected randomly from hospitals, food sellers, and transporters in all three districts of Khartoum, Bahri, and Omdurman. …”
Get full text

The Effect of Face-to-Face Education and Educational Booklet on Heart Health Indexes of the Hospitalized Patients with Myocardial Infarction by Safar Ali Esmaeili Vardanjani, Laleh Fanisaberi, Firozeh Alirezaee Shahraki, Ahmad Khalilzadeh, Abdolazim Tavakoli Vardanjani, Fatemeh Ghani Dehkordi

“…In this study, 112 patients with myocardial infarction who were below the age of 70 were selected randomly and divided into two groups (case group and control group) after being matched based on age and sex. …”
Get full text

Mycobacterium spp. exposure, childhood vaccinations, and early childhood brain and CNS cancers by Samer Singh, Rakesh K. Singh

“…Exploration of BCNS cancer incidence and prevailing immune correlates in matched cohorts, along with prospective randomized controlled trials, may be warranted to conclusively ascertain the impact of childhood vaccinations and boosters (including natural exposure) on early childhood BCNS cancer incidence.…”
Get full text

Development of a 3-MicroRNA Signature and Nomogram for Predicting the Survival of Patients with Uveal Melanoma Based on TCGA and GEO Databases by Jun Zuo, Hongquan Ye, Jing Tang, Jianqun Lu, Qi Wan

“…The patients were further randomly assigned to a training set (n = 40, used to identify key miRNAs) and a testing set (n = 40, used to internally verify the signature). …”
Get full text

Anti malicious KGC certificateless signature scheme based on blockchain and domestic cryptographic SM9 by Fei TANG, Ning GAN, Xianggui YANG, Jinyang WANG

“…The certificateless cryptosystem can solve the problems of certificate management and key escrow at the same time, but its security model always assumes that Type II adversary (named malicious KGC) will not launch public key replacement attacks.This security assumption has certain limitations in real-world applications.As an efficient identity-based cryptographic scheme, SM9 signature scheme adopts R-ate bilinear pairing which has good security and high computational efficiency.However, it requires KGC to generate and manage keys for users, so it has the problem of key escrow.In view of the above problems, a certificateless signature scheme against malicious KGC was constructed based on blockchain and SM9 signature algorithm.Based on the properties of decentralization and tamper-proof of blockchain, the proposed scheme used the smart contract to record part of the public key corresponding to the user’s secret value on the blockchain.Then, the verifier can revoke the smart contract to query the user’s public key during the signature verification stage.Therefore, the proposed scheme ensured the authenticity of the user’s public key.The user’s private key consisted of the partial private key generated by KGC and a secret randomly chosen by the user.The user required the partial private key generated by KGC to endorse his identity identifier when the user generates the private key for the first time.Subsequently, the private key can be independently updated by changing the secret and the corresponding partial public key.During this process, the identity remains unchanged, which provided a viable solution for key management in decentralized application scenarios.The blockchain relied on the consensus mechanism to ensure the consistency of the distributed data.Based on the traceability of the blockchain, the change log of user’s partial public key was stored in the blockchain, which can trace the source of malicious public key replacement attacks and thereby prevent malicious KGC from launching public key replacement attacks.According to the experimental simulation and security proof results, the total overhead of signature and verification of the proposed scheme is only 7.4ms.Compared with similar certificateless signature schemes, the proposed scheme can effectively resist public key replacement attacks and has higher computational efficiency.…”
Get full text

Autologous Peripheral Blood-Derived Orthobiologics for the Management of Shoulder Disorders: A Review of Current Clinical Evidence by Ashim Gupta, Nicola Maffulli

“…Given the dearth of relevant literature and limitations of the available studies, more prospective clinical studies, and ideally, randomized controlled trials, with extended follow-up are necessary to establish the efficacy of APBOs and to select the ideal APBO for the management of shoulder disorders.…”
Get full text

Knowledge, Attitude, and Practice towards Malaria among People Attending Mekaneeyesus Primary Hospital, South Gondar, Northwestern Ethiopia: A Cross-Sectional Study by Belaynesh Tazebew Flatie, Abaineh Munshea

“…A structured questionnaire was administered to collect data on sociodemographic characteristics and KAP of 390 randomly selected individuals. The data collecting tool was pretested before commencing the actual data collection. …”
Get full text

Efficacy of Exenatide Administered Twice Daily in Body Mass Index Reduction in Patients with Type 2 Diabetes Mellitus by Jie Zhang, Tong-Zhang Xian, Yu Teng, Xiuzhi Wang, Ming-Xiao Wu, Chen Li, Weihao Wang, Fuli Man, Xianbo Zhang, Xiaoxia Wang, Li-Xin Guo

“…This retrospective cohort study used data from our randomized controlled trial. A total of 27 T2DM patients treated with combination therapy of exenatide twice daily and metformin for 52 weeks were included. …”
Get full text

The Impact of Visual Perturbation Neuromuscular Training on Landing Mechanics and Neural Activity: A Pilot Study by Timothy R Wohl, Cody R Criss, Adam L Haggerty, Justin L Rush, Janet E Simon, Dustin R Grooms

“… # Conclusion VPNT provides a clinically feasible means to perturbate visual processing during training that improves athletes’ real-time landing mechanics and promotes neural efficiency for lower extremity movement, providing the exploratory groundwork for future randomized controlled trials. # Level of evidence Level 3…”
Get full text

Risk Factors Associated with Helminthic Intestinal Infection in Lurambi Subcounty, Kakamega, Kenya by Ruth W. Kiiti, Elizabeth N. Omukunda, Jackson C. Korir

“…A cross-sectional study was conducted from Jan 2020 to Feb 2020 among 392 randomly selected primary school-going children aged 5 to 14 years old in six primary schools. …”
Get full text

Exploration of the optimal deep learning model for english-Japanese machine translation of medical device adverse event terminology by Ayako Yagahara, Masahito Uesugi, Hideto Yokoi

“…Methods English-Japanese parallel data for IMDRF-AET published by the Ministry of Health, Labor and Welfare in Japan was obtained from 50 sentences randomly extracted from the terms and their definitions. …”
Get full text