Notch Signaling Pathway Promotes Th17 Cell Differentiation and Participates in Thyroid Autoimmune Injury in Experimental Autoimmune Thyroiditis Mice by Hao Liu, Yiwen Li, Yujiao Zhu, Lei Ma, Haibo Xue

“…Experimental mice were randomly divided into a control group, an EAT-A group (porcine thyroid immunoglobulin- (pTg-) treated mice) and an EAT-B group (treated with the DAPT γ-secretase inhibitor before pTg). …”
Get full text

Balance rehabilitation with a virtual reality protocol for patients with hereditary spastic paraplegia: Protocol for a clinical trial. by Bianca Simone Zeigelboim, Maria Renata José, Geslaine Janaina Bueno Dos Santos, Maria Izabel Rodrigues Severiano, Hélio Afonso Ghizoni Teive, José Stechman-Neto, Rosane Sampaio Santos, Cristiano Miranda de Araújo, Bianca Lopes Cavalcante-Leão

“…<h4>Methods</h4>In this randomized controlled clinical trial from the Rebec platform RBR-3jmx67 in which allocation concealment was performed and the evaluators be blinded will be included. …”
Get full text

A Characteristics of Milk Caramel Candy with the Addition of Stevia (Stevia Rebaudiana Bertoni) Extract Leaf Powder by Yola Andriani, Daimon Syukri, Rini Rini

“…This study used a completely randomized design (CRD) with 5 treatments and 3 replications. …”
Get full text

An Intervention Study: Does a Cognitive Reappraisal Technique Reduce the Perceived Stress in Fourth-Year Dental Students in New Zealand? by Alana Smith, Imogen Scott, Jithendra Ratnayake, Kate Newsham-West, Peter Cathro

“…A survey was emailed to all fourth-year dental students, inviting them to respond to a 20-item questionnaire adapted from the Dental Environmental Stress (DES) Survey. Respondents were randomly assigned to reappraisal intervention/experimental (EXP) and control intervention (CON) groups, and each group was asked to watch an educational video. …”
Get full text

Exploring physician approaches to conflict resolution in end-of-life decisions in the adult intensive care unit: protocol for a systematic review of qualitative research by Richard Huxtable, Harleen Kaur Johal, Giles Birchley

“…Two reviewers will independently screen either all or a randomly selected sample of studies, with a third reviewer independently screening studies of uncertain eligibility. …”
Get full text

The Effect Dose and Soaking Time of Camellia sinensis Solution to the Egg Adhesion and Hatching of Pangasionodon hypophthalmus by Aldi Baihaki, Nur Asiah, Nuraini Nuraini

“…This study used a Completely Randomized Design Factorial with 2 factors. The first factor was the dose (g/L) of the black tea with 4 levels; 0 (D0), 8 (D8), 10 (D10), and 12 (D12). …”
Get full text

Performance of vermicomposted wastes for tomato (Lycopersicon Esculentum Mill.), production: A case study of Embu, Kenya by Miriam Mochache, Rebecca Yegon, Onesmus Ngetich

“…Purpose To investigate the effect of vermicomposted kitchen, market and tea wastes on tomato growth and yield and assess the benefits and costs that arise.Method A field experiment arranged in the randomized complete block design with five experimental treatments: vermicomposted kitchen, market, tea wastes, NPK fertilizer and a control, replicated thrice was conducted. …”
Get full text

Blood Pressure-Lowering Mechanisms of the DASH Dietary Pattern by Pao-Hwa Lin, Jason D. Allen, Yi-Ju Li, Miao Yu, Lillian F. Lien, Laura P. Svetkey

“…All consumed a control diet for one week, then were randomized to control or DASH for another two weeks (week one and two). …”
Get full text

Irrational medicine use and its associated factors in conflict-affected areas in Mali: a cross-sectional study by Mohamed Ali Ag Ahmed, Alassane Seydou, Issa Coulibaly, Karina Kielmann, Raffaella Ravinetto

“…Methods We conducted a cross-sectional study in twenty randomly selected community health centres (CHCs) in four health districts, by applying the World Health Organisation and International Network on Rational Use of Drugs core forms for the rational use of medicines. …”
Get full text

Single Cone Obturation versus Cold Lateral Compaction Techniques with Bioceramic and Resin Sealers: Quality of Obturation and Push-Out Bond Strength by Ahmad Nouroloyouni, Vahid Samadi, Amin Salem Milani, Sara Noorolouny, Haleh Valizadeh-Haghi

“…This in vitro experimental study was conducted on 88 single-rootedsingle-canal teeth with straight roots that were randomly divided into four groups (n = 22). All teeth were decoronated and underwent cleaning and shaping. …”
Get full text

Cost-effectiveness of vector control for supplementing mass drug administration for eliminating lymphatic filariasis in India. by Donald S Shepard, Aung K Lwin, Sunish I Pulikkottil, Mariapillai Kalimuthu, Natarajan Arunachalam, Brij K Tyagi, Graham B White

“…Data came from historical controls and a three-arm cluster randomized trial of 36 villages at risk of LF transmission in Tamil Nadu, India. …”
Get full text

Genetic Variation of New Purple-Fleshed Sweet Potato (Ipomoea batatas L.) Genotypes in Indonesia by Multivariate Analysis by Debby Ustari, Arif Affan Wicaksono, Vergel Concibido, Tarkus Suganda, Dedi Ruswandi, null Ruminta, Agung Karuniawan

“…The research trials were arranged in a randomized block design, with nine new PFSP genotypes from polycrosses breeding as treatments and three check varieties in four growing environments in West Java, i.e., Cilembu, Jatinangor, Maja, and Karangpawitan during one season. …”
Get full text

Human Placenta-Derived Mesenchymal Stem Cells Ameliorate Diabetic Neuropathy via Wnt Signaling Pathway by Songsong Pan, Sushant S. Hada, Yang Liu, Chao Hu, Mengdie Zhou, Shaoqiu Zheng, Minjie Xu, Changsheng Shi, Shiwu Yin, Xiaoyun Xie

“…Twenty-seven male db/db mice were randomly categorized into the control group, PMSC group, and PMSC treatment with Wnt inhibitor treatment group. …”
Get full text

Therapeutic Potential of Liraglutide for Diabetes–Periodontitis Comorbidity: Killing Two Birds with One Stone by Man Yang, Yunqing Pang, Minyu Pei, Yuanyuan Li, Xuemin Yuan, Rongbing Tang, Jing Wang

“…Male Wistar rats (n=46) were randomly divided into four groups: control group (n=8), LIRA group (n=8), diabetes-associated periodontitis+0.9% saline group (diabetic periodontitis (DP)+NaCl group, n=15), and diabetes-associated periodontitis+LIRA group (DP+LIRA group, n=15). …”
Get full text

Shrimp allergen extract immunotherapy induces prolonged immune tolerance in a gastro-food allergy mouse model. by Honey Dzikri Marhaeny, Lutfiatur Rohmah, Yusuf Alif Pratama, Salsabilla Madudari Kasatu, Andang Miatmoko, Rafi Addimaysqi, Geert van den Bogaart, Franz Y Ho, Muhammad Taher, Junaidi Khotib

“…For the immunotherapy evaluation, mice (n = 24) were intraperitoneally (i.p.) sensitized with 1 mg alum and 100 μg SAE in PBS on days 0, 7, and 14 and randomly divided into four groups of six: a negative control (NC) and high- to low-dose immunotherapy (HI, MI, and LI). …”
Get full text

The effect of spiritual counseling based on the sound heart model on resilience and parenting competence in mothers with intellectually disabled children by Arefeh Sadeghi, Anahita Khodabakhshi-Koolaee, Minoo Asadzandi

“…A total of 40 mothers were selected as the participants through voluntary sampling and were randomly placed into two control and experimental groups. …”
Get full text

Sago Starch Bagea Cookies with Moringa Leaf Powder Composite as a Fiber and Antioxidant Enhancer by Herlina Herlina, Rodame Bonalisa Sinaga

“…This study used an experimental method with a completely randomized design (CRD) with a single factor, namely the addition of moringa leaf powder 3%, 6%, 9%, 12%, 15%. …”
Get full text

Histopathological and Biochemical Assessment of Neuroprotective Effects of Sodium Valproate and Lutein on the Pilocarpine Albino Rat Model of Epilepsy by Aziza Rashed Al-Rafiah, Khlood Mohammed Mehdar

“…To achieve this aim, fifty rats were randomly divided into five groups. Group I: control, group II: received PLC (400 mg/kg intraperitoneally), group III: received PLC + SVP (500 mg/kg orally), group IV: received PLC + SVP + L (100 mg/kg orally), and group V: received (PLC + L). …”
Get full text

Neuroprotective Effect of Wharton’s Jelly-Derived Mesenchymal Stem Cell-Conditioned Medium (WJMSC-CM) on Diabetes-Associated Cognitive Impairment by Improving Oxidative Stress, Neu... by Zohre Aghaei, Narges Karbalaei, Mohammad Reza Namavar, Masoud Haghani, Mahboobeh Razmkhah, Mahdi Khorsand Ghaffari, Marzieh Nemati

“…In the current study, we aimed to examine the effects of Wharton’s jelly-derived mesenchymal stem cell-conditioned medium (WJMSC-CM) on learning and memory, oxidative stress, apoptosis, and histological changes in the hippocampus of diabetic rats. Randomly, 35 male Sprague Dawley rats weighing 260–300 g were allocated into five groups: control, diabetes, and three diabetic groups treated with insulin, WJMSC-CM, and DMEM. …”
Get full text

Evaluation of irrigation management in different stages of growth on the yield and water productivity in cowpea plant in field and model conditions by Faranak Baradaran-Hezaveh, Hossein Babazadeh, Ebrahim Amiri, Hossein Ebrahimi

“…The experiment was conducted in the form of a randomized complete block design with three replications in the north of Iran during 2017 and 2018. …”
Get full text