Effects of minocycline on patients with acute anterior circulation ischaemic stroke undergoing intravenous thrombectomy (MIST-A): the study protocol for a multicentre, prospective,... by Xiao Zhang, Li Yao, Jingjing Zhao, Hao Zhu, Bin Wang, Huiping Zhang, Wen Jiang, Dong Wei, Wen Liu, Zhongqing Sun, Weiwang Li, Xiangjun Yuan, Xingshun Ma, Junpeng Meng, Yi Jia, Na Qin

“…These patients will be randomly divided into two groups: one receiving minocycline in addition to standard care and the other receiving only standard care. …”
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Increased Accuracy of Emotion Recognition in Individuals with Autism-Like Traits after Five Days of Magnetic Stimulations by Pingping Liu, Guixian Xiao, Kongliang He, Long Zhang, Xinqi Wu, Dandan Li, Chunyan Zhu, Yanghua Tian, Panpan Hu, Bensheng Qiu, Gong-Jun Ji, Kai Wang

“…It is still undetermined whether it is possible to improve the social function of ALT individuals through noninvasive neural modulation. To this end, we randomly assigned ALT individuals into the real (n=16) and sham (n=16) stimulation groups. …”
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An injectable, expandable polyacrylamide cryogel decreases blood loss and improves survival in a porcine model of junctional hemorrhage by Al-Murtadha Al-Gahmi, Syed Muntazir Andrabi, S. M. Shatil Shahriar, Carlos P. Jara, Jingwei Xie, Mark A. Carlson

“…Splenectomized domestic swine (~ 40 kg; N = 37) were randomized to no treatment (N = 8), EPC (N = 7), EPC + thrombin (N = 6), XStat (N = 7), and Combat Gauze (CG, N = 9). …”
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Advancing allergic rhinitis research through phenome-wide association studies: Insights from known genetic loci by Xingling Tan, MD, Zhouyouyou Xiao, MB, Yao Wen, MD, Han Liu, MD, Wei Yu, MD

“…Subsequently, linkage disequilibrium score regression (LDSC) and bidirectional two-sample mendelian randomization (TSMR) analyses were used to further analyze the genetic correlation and causal relationships between significant and potentially related phenotypes and AR. …”
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Anato-morphological and chemical characterization of bamboo (Guadua amplexifolia J. Presl) from San Jorge River Basin, Colombia by Yiniva Camargo Caicedo, Jorge Augusto Montoya Arango, Andrés Prieto Muriel

“…The vascular bundles in the internal and transitional zones of the walls were oriented randomly. Furthermore, the analysis of the lignocellulosic composition of Guadua amplexifolia J. …”
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Interpretable flash flood susceptibility mapping in Yarlung Tsangpo River Basin using H2O Auto-ML by Fei He, Suxia Liu, Xingguo Mo, Zhonggen Wang

“…The flash flood susceptibility map generated by the best-performing eXtreme Randomized Trees (XRT) model showed that 8.92%, 12.95%, 15.42%, 31.34%, and 31.37% of the study area exhibited very high, high, moderate, low, and very low flash flood susceptibility, respectively, with approximately 74.9% of the historical flash floods occurring in areas classified as moderate to very high susceptibility. …”
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The utility of artificial intelligence in identifying radiological evidence of lung cancer and pulmonary tuberculosis in a high-burden tuberculosis setting by Z Z Nxumalo, E M Irusen, B W Allwood, M Tadepalli, J Bassi, C F N Koegelenberg

“…These chest radiographs were de-identified and randomly uploaded by a blinded investigator into qXR software. …”
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A Comprehensive Exploration of the Fatty Acids Profile, Cholesterol, and Tocopherols Levels in Liver from Laying Hens Fed Diets Containing Nonindustrial Hemp Seed by Youssef Rbah, Yassine Taaifi, Aymane Allay, Kamal Belhaj, Reda Melhaoui, Nadia Houmy, Abdessamad Ben Moumen, Embarek Azeroual, Mohamed Addi, Farid Mansouri, Hana Serghini-Caid, Ahmed Elamrani

“…This study investigates the impact of dietary nonindustrial Moroccan hemp seed (HS) on the fatty acid profile, cholesterol, and tocopherol levels, in the liver of 120 Lohmann brown laying hens aged 22 weeks during 12 weeks of treatment. The hens are randomly allocated into four treatment groups, each subdivided into six replicates with five birds in each replicate. …”
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Efficacy and safety of topical versus intravenous tranexamic acid in spinal surgery: a systematic review and meta-analysis by Chengxin Xie, Liwei Zhang, Guoping Cai, Yongwei Su, Peng Wang, Hua Luo

“…Results The meta-analysis of randomized controlled trials indicated that IBL and total blood loss were markedly higher in the group receiving topical TXA compared to the intravenous TXA group. …”
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Study protocol of the PRINCESS trial—PReoperative INtermittent fasting versus CarbohydratE loading to reduce inSulin resiStance versus standard of care in orthopaedic patients: a r... by Markus W Hollmann, Abraham H Hulst, Benedikt Preckel, Jeroen Hermanides, Ayla Y Stobbe, Eline S de Klerk, Robert van Wilpe, Arthur J Kievit, Kee Fong Choi, Mireille F M van Stijn

“…A total of 75 orthopaedic patients presenting for elective intermediate to major surgery at a Dutch academic hospital will be randomly assigned to a control group (standard preoperative fasting), a TRF group or a CHL group. …”
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Clinical Results of Diffractive, Refractive, Hybrid Multifocal, and Monofocal Intraocular Lenses by Agnieszka Dyrda, Ana Martínez-Palmer, Daniel Martín-Moral, Amanda Rey, Antonio Morilla, Miguel Castilla-Martí, Janny Aronés-Santivañez

“…Three hundred twenty eyes (160 patients) underwent cataract surgery with randomized IOLs bilateral implantation. Changes in uncorrected and distance-corrected logMAR distance, intermediate and near (UNVA and DCNVA) visual acuity (VA), contrast sensitivity (CS), presence of dysphotopsia, spectacle independence, and patient satisfaction were analyzed. …”
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Farmer’s Knowledge on Thaumatotibia Leucotreta (Meyrick) an Economic Pest of Avocado Production in Tanzania by Juliana G. Shikoshi, Angela G. Mkindi, Patrick A. Ndakidemi, Ernest R. Mbega, Kelvin M. Mtei

“…A total of 45 orchards were inspected to determine the infestation level of T. leucotreta in 225 randomly selected avocado trees. The findings revealed that 56.1% (n = 330) of the farmers had no idea about any insect pests infesting avocado fruits, while 77.6% (n = 456) of farmers were unaware of T. leucotreta, presence; however, only 22.4% (n = 132) confirmed to have seen damage symptoms caused by the pest on avocado fruits. …”
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Trichloroacetic Acid Peeling for Treating Photoaging: A Systematic Review by Irma Bernadette S. Sitohang, Lili Legiawati, Lis Surachmiati Suseno, Fadhila Dea Safira

“…Five studies included three randomized comparison studies and two prospective cohort studies. …”
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Efficacy of Administration of an Angiotensin Converting Enzyme Inhibitor for Two Years on Autonomic and Peripheral Neuropathy in Patients with Diabetes Mellitus by Triantafyllos Didangelos, Konstantinos Tziomalos, Charalambos Margaritidis, Zisis Kontoninas, Ioannis Stergiou, Stefanos Tsotoulidis, Eleni Karlafti, Alexandros Mourouglakis, Apostolos I. Hatzitolios

“…Sixty-three consecutive patients with diabetes mellitus [43% males, 27 with type 1 DM, mean age 52 years (range 22–65)], definite DCAN [abnormal results in 2 cardiovascular autonomic reflex tests (CARTs)], and DPN were randomized to quinapril 20 mg/day (group A, n=31) or placebo (group B, n=32) for 2 years. …”
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Can verbal autopsies be used on a national scale? Key findings and lessons from South Africa's national cause-of-death validation study by Monique Maqungo, Nadine Nannan, Beatrice Nojilana, Erin Nichols, Diane Morof, Mireille Cheyip, Chalapati Rao, Carl Lombard, Jessica Price, Kathleen Kahn, Lorna J. Martin, Francois Bezuidenhout, Ria Laubscher, Chodziwadziwa Kabudula, Tracy Glass, Oluwatoyin Awotiwon, Nesbert Zinyakatira, Noluntu Funani, Jané Joubert, Debbie Bradshaw, Pamela Groenewald

“…Methods We recruited next of kin from 27 randomly selected sub-districts (10.5%) across South Africa between September 2017 and April 2018. …”
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Effects of Ethyl Pyruvate on Bile Duct Ligation-Induced Liver Fibrosis by Regulating Nrf2 Pathway and Proinflammatory Cytokines in Rats by Yonghua Zong, Mingxiao Zhang, Shuai Li, Wenqian Qi, Juan Li, Tonghua Liu, Huijun Yang, Chen Lu, Xiaosong Hu

“…Material and Method. Rats were randomly divided into three groups: the sham group, the BDL group, and the BDL+EP group. …”
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Effects of Physical Exercise Breaks on Executive Function in a Simulated Classroom Setting: Uncovering a Window into the Brain by Qian Yu, Zhihao Zhang, Sebastian Ludyga, Kirk I. Erickson, Boris Cheval, Meijun Hou, Dominika M. Pindus, Charles H. Hillman, Arthur F. Kramer, Ryan S. Falck, Teresa Liu‐Ambrose, Jin Kuang, Sean P. Mullen, Keita Kamijo, Toru Ishihara, David A. Raichlen, Matthew Heath, David Moreau, André O. Werneck, Fabian Herold, Liye Zou

“…Abstract Acknowledging the detrimental effects of prolonged sitting, this study examined the effects of an acute exercise break during prolonged sitting on executive function, cortical hemodynamics, and microvascular status. In this randomized crossover study, 71 college students completed three conditions: (i) uninterrupted sitting (SIT); (ii) SIT with a 15 min moderate‐intensity cycling break (MIC); and (iii) SIT with a 15 min vigorous‐intensity cycling break (VIC). …”
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Evaluating the antagonist effect of naltrexone implant via opioid challenge tests with escalating doses of hydromorphone injection in former heroin dependent patients by Wei Qu, Xuyi Wang, Chongyang Dong, Tao Zhang, Shugui Yin, Zhijun Sun, Shiqiang Wang, Anni Guo, Wei Hao

“…Thirty-one former opioid-dependent individuals were randomized to the 0.9g or the 1.5g NTX-IMP group. All subjects exhibited significant antagonistic effects during hydromorphone challenge test. …”
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Benefits and Harms of Extending the Duration of Dual Antiplatelet Therapy after Percutaneous Coronary Intervention with Drug-Eluting Stents: A Meta-Analysis by Chun Shing Kwok, Heerajnarain Bulluck, Alisdair D. Ryding, Yoon K. Loke

“…We conducted a systematic review and meta-analysis of randomized controlled trials evaluating risk of adverse events in participants receiving different durations of DAPT following insertion of drug-eluting stents. …”
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Complete Feed Silage Innovation: Utilization of Agro-Industry By-Products with Chestnut Tannin as Additives by Sadarman Sadarman, Dewi Febrina, Rahmi Febriyanti, Reski Peter, Zulkarnain Zulkarnain, Sirajuddin Sirajuddin, Imam Gazali, Agus Hafid, Novia Qomariyah, Sandri Sastrawan, Tri Rachmanto Prihambodo

“…The research utilized a Completely Randomized Design with five treatments and five replications. …”
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