Renal Replacement Therapy in the Critical Care Setting by Adeel Rafi Ahmed, Ayanfeoluwa Obilana, David Lappin

“…Recently published randomized control trials (RCTs) have further questioned our understanding of RRT in critical care. …”
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Functional Multipotency of Stem Cells: What Do We Need from Them in the Heart? by Pablo Díez Villanueva, Ricardo Sanz-Ruiz, Alberto Núñez García, María Eugenia Fernández Santos, Pedro L. Sánchez, Francisco Fernández-Avilés

“…After more than ten years of human research in the field of cardiac regenerative medicine, application of stem cells in different phases of ischemic heart disease has come to age. Randomized clinical trials have demonstrated that stem cell therapy can improve cardiac recovery after the acute phase of myocardial ischemia and in patients with chronic ischemic heart disease, and several efficacy phase III trials with clinical endpoints are on their way. …”
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Hypolipidemic and Hepatoprotective Effects of High-Polydextrose Snack Food on Swiss Albino Mice by Jin Han Yang, Thi Thu Tra Tran, Van Viet Man Le

“…In this study, the hepatoprotective and hypolipidemic effects of high-polydextrose snack food on Swiss albino mice were investigated. The mice were randomly divided into three groups: control diet, high-fat diet, and high-fat and fiber diet groups. …”
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Process Evaluation of the Implementation of the Secondary 2 Program of Project P.A.T.H.S. in the Experimental Implementation Phase by Daniel T. L. Shek, Tak Yan Lee, Rachel C. F. Sun

“…Observers carried out process evaluation in the form of systematic observations of curriculum units in four randomly selected schools. Results showed that the overall level of program adherence was generally high, ranging from 70 to 95%, with an average of 83.6%. …”
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POSITIONING OF WHEAT CULTIVARS AND THEIR RELATION WITH THE NUTRITIONAL QUALITY OF GRAINS by Willyan Júnior Adorian Bandeira, Ivan Ricardo Carvalho, Murilo Vieira Loro, Leonardo Cesar Pradebon, João Pedro Dalla Roza, Jaqueline Piesanti Sangiovo, Kassiana Kehl

“…Five wheat genotypes were sown (BRS Parrudo, LG ORO, Mirante, ORS 1403, and TBIO Sinuelo), using a randomized block experimental design with two replications. …”
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Failure of Recombinant Activated Factor VII in Treatment of Diffuse Alveolar Hemorrhage due to Cryoglobulinemic Vasculitis by Dania Khoulani, Bharat Rao, Ammar Khanshour, Philip Kuriakose, Lenar Yessayan

“…It is increasingly being used in life-threatening hemorrhage in a variety of other settings in which conventional therapy is unsuccessful. Randomized controlled trials of rFVIIa in DAH are lacking. …”
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The Effect of Boiling Time on Polyphenol Compounds and Antioxidant Activity of Ciplukan (Physalis Angulata .L) by Tuty Anggraini, Busra Al-Hafit, Netty Sri Indeswari, Daimon Syukri

“…This research used Randomized Block Design (RBD) with five groups (leaves, stems, fruit, roots, and mixture of each part of the plant ) and three treatments (10, 20 and 30 minutes). …”
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Revisiting substance P in migraine: a methodological approach inspired by anti-CGRP and anti-PACAP success by Lanfranco Pellesi, Lars Edvinsson

“…Using an established methodological framework, migraine-inducing properties of substance P can be evaluated through randomized, double-blind, placebo-controlled crossover studies involving healthy volunteers and individuals with a history of migraine. …”
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Growth of olive saplings in different media containing artificial and natural super absorbents at two irrigation intervals by A. Mohammadi Torkashvand, H. Shahin, M. Mohammadi

“…A factorial experiment was conducted to evaluate the impact of super absorbents and organic wastes of rice, olive marc, vermicompost and farmyard manure on the soil water holding capacity and the growth of plant based on randomized complete block design with 13 treatments at two irrigation intervals 5 and 10 days. …”
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Exploring cerebellar transcranial magnetic stimulation in post-stroke limb dysfunction rehabilitation: a narrative review by Zhan Wang, Likai Wang, Likai Wang, Fei Gao, Yongli Dai, Chunqiao Liu, Jingyi Wu, Mengchun Wang, Qinjie Yan, Yaning Chen, Chengbin Wang, Litong Wang

“…It synthesizes findings from randomized controlled trials and case studies, examining the efficacy, safety, and underlying mechanisms of cerebellar TMS. …”
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Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19 by Aliede E. in ‘t Veld, Manon A. A. Jansen, Luuk C. A. Ciere, Matthijs Moerland

“…This is supported by the initial outcomes of the well-designed randomized controlled trials: so far, evidence for a beneficial effect of HCQ treatment for COVID-19 is weak and conflicting.…”
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Clinical and Radiographic Success of Selective Caries Removal to Firm Dentin in Primary Teeth: 18-Month Follow-Up by Tássia Carina Stafuzza, Luciana Lourenço Ribeiro Vitor, Daniela Rios, Thiago Cruvinel Silva, Maria Aparecida Andrade Moreira Machado, Thais Marchini Oliveira

“…Notwithstanding, further randomized clinical trials with longer following-up periods are still necessary.…”
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Epi-Off versus Epi-On Corneal Collagen Cross-Linking in Keratoconus Patients: A Comparative Study through 2-Year Follow-Up by F. Cifariello, M. Minicucci, F. Di Renzo, D. Di Taranto, G. Coclite, S. Zaccaria, S. De Turris, C. Costagliola

“…Forty eyes from 32 patients with progressive keratoconus were prospectively enrolled from June 2014 to June 2015 in this nonblinded, randomized comparative study. Twenty eyes were treated by CXL epi-off and 20 by CLX epi-on, randomly assigned, and followed for 2 years. …”
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Development and clinical assessment of a novel probiotic candy in the prevention of respiratory infections in asthmatic children by Rana Tafrishi, Hamid Ahanchian, Seyed ali Jafari, Abolfazl Pahlevanloo, Hamidreza Kianifar, Mohammadali Kiani, Nasrin Moazzen, Tahereh sadeghi, Peter D. Sly

“…Methods & materials: In this randomized trial, 69 children aged 7–11 years with mild intermittent asthma were randomized to receive probiotic candy (containing 1010 CFU probiotic Bacillus coagulans) or placebo candy, daily for 2 months. …”
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The Physiological Impacts of the Low- and Moderate-Volume-HIIT with or without Nano-Curcumin Supplement in Women in Menopause with Obesity by Valiollah Dabidi Roshan, Sepideh Noorbakhsh, Seyedeh Fatemeh Ziatabar Ahmadi, Mehdi Nikseresht

“…In a double blind, randomized, placebo-controlled study, 53, moderately obese menopause women (average age 45–60 yrs, BMI > 30 kg/m2, WC for >85 cm, and body fat > 35%) were randomly assigned to undertake either LV-HIIT, MV-HIIT, or NaC supplement (daily 80 mg in two 40-mg capsules) for two sessions per week for 8 weeks. …”
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Effects of the MyBFF@school program on anthropometry and body composition among overweight and obese adolescent schoolchildren by Nur Zati Iwani Ahmad Kamil, Abdul Halim Mokhtar, Abqariyah Yahya, Fuziah Md. Zain, Rusidah Selamat, Zahari Ishak, Muhammad Yazid Jalaludin

“…Methods This is a cluster randomized controlled trial which involved schoolchildren aged 13, 14 and 16 years old from 15 out of 415 government secondary schools in central Peninsular Malaysia which were randomly assigned into six intervention (N = 579 schoolchildren) and nine control (N = 462 schoolchildren).The intervention group followed MyBFF@school program carried out by trained personnel for 6 month while the control group only followed the existing school curriculum by the Ministry of Education. …”
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Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China. by Huan Yun, Liang Sun, Qingqing Wu, Geng Zong, Qibin Qi, Huaixing Li, He Zheng, Rong Zeng, Liming Liang, Xu Lin

“…Summary data for 2-sample Mendelian randomization were obtained from genome-wide association studies of circulating sphingolipids and the China Health and Nutrition Survey (n = 5,731). …”
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Effect of Qing'e Formula on OPN, BSP and Integrin ɑ_vβ₃Expression in Bone Tissue of Ovariectomized Rats by Yuqing SUN, Wenjuan LUO, Bingqi WANG, Xiang CHEN, Xiaokang JIA, Yanping LIN

“…Three days after operation, the rats were fed daily with normal saline (the sham-operated group, the saline group), Qing'e formula (the Qing'e formula group) and Gushukang (the Gushukang group), respectively. Ten rats were randomly chosen from each group, and sacrificed on week 4, 8 and 12, after treatment. …”
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Cost-utility and cost–benefit analysis of a multi-component intervention (NEXpro) for neck-related symptoms in Swiss office workers by Beatrice Brunner, Andrea Martina Aegerter, Venerina Johnston, Thomas Volken, Manja Deforth, Gisela Sjøgaard, Achim Elfering, Markus Melloh, the NEXpro Collaboration Group

“…Methods The study was designed as a stepped-wedge cluster randomized controlled trial and assessed using an employer’s perspective. …”
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An App-Based Intervention With Behavioral Support to Promote Brisk Walking in People Diagnosed With Breast, Prostate, or Colorectal Cancer (APPROACH): Process Evaluation Study by Fiona Kennedy, Susan Smith, Rebecca J Beeken, Caroline Buck, Sarah Williams, Charlene Martin, Phillippa Lally, Abi Fisher

“…Contextual factors will be important to consider when interpreting outcomes in the larger APPROACH randomized controlled trial. International Registered Report Identifier (IRRID)RR2-10.1186/s40814-022-01028-w…”
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