Helicobacter pylori Eradication in Non-Ulcer Dyspepsia: Clearing up the Controversy by Carlo A Fallone

“…Veldhuyzen van Zanten et al conducted a double-blind, randomized, multicentre study comparing triple therapy for Helicobacter pylori eradication to placebo for the treatment of nonulcer dyspepsia (NUD) symptoms in adult patients (1). …”
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Design of field trials for the evaluation of transmissible vaccines in animal populations. by Justin K Sheen, Lee Kennedy-Shaffer, Michael Z Levy, Charlotte Jessica E Metcalf

“…Here, we establish the conditions under which a two-stage randomized field trial can characterize the protective effects of a transmissible vaccine relative to a traditional vaccine. …”
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Prospective study on the role of preoperative mannitol in capsulorhexis and reducing intraoperative complications in primary angle-closure disease surgery by Zhiqiao Liang, Hongyan Li, Xianru Hou, Kangyi Yang, Kun Lv, Yao Ma, Ye Lu, Kuankuan Wu, Huijuan Wu

“…Methods In this prospective randomized controlled trial, 65 PACG eyes were randomized into the mannitol and control groups. …”
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A 5-HT Antagonist (UP 26-91) versus Codeine and Placebo in a Human Experimental Pain Study by Lars Arendt-Nielsen, Poul Pedersen, Lars Poulsen, Ole Kæseler Andersen, Peter Bjerring, Isabelle Coste, Jorge Insuasty, Søren Sindrup, Asbjørn Mohr Drewes

“…BACKGROUND: This double-blind, randomized, crossover study compared the potential analgesic effect of the serotonin receptor antagonist UP 26-91 (50 mg, 150 mg and 300 mg) with that of codeine (100 mg) and placebo by use of different human experimental pain models.…”
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Systematic review and meta-analysis of T1 glottic cancer outcomes comparing CO2 transoral laser microsurgery and radiotherapy by Michael F. Vaculik, Colin A. MacKay, S. Mark Taylor, Johnathan R. B. Trites, Robert D. Hart, Matthew H. Rigby

“…Limitations of our study include lack of randomized control trials, and non-randomized allocation of patients to treatment groups. …”
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A comparative study on the efficacy of over-the-counter wax solvents versus distilled water for managing ear cerumen by Syed. Mohd. Ahmad, Rajesh Kumar Suman, Simran Kaur Pal, Ayush Agrawal

“…Materials and Methods: This double-masked, randomized prospective cohort study enrolled 236 patients seeking treatment for ear wax-related concerns at the Ear, Nose, Throat outpatient department. …”
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Within-hospital Temporal Clustering of Postoperative Complications and Implications for Safety Monitoring and Benchmarking Using ACS-NSQIP Data by Mark E. Cohen, PhD, Yaoming Liu, PhD, Clifford Y. Ko, MD, MS, MSHS, FACS, Bruce L. Hall, MD, PhD, MBA, FACS

“…There was 1 significant difference in the number of clusters when comparing data with all adjustments and after data were randomized (0.24 and 0.25 for mortality; P = 0.853; 0.80 and 0.82 for morbidity; P = 0.529; and 0.36 and 0.46 [randomized data had more clusters] for SSI; P = 0.001; using paired t tests) for mortality, morbidity, and SSI, respectively. …”
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How effective is the addition of specific exercise therapy for patients after anterior cruciate ligament surgery? A systematic review and meta-analysis by Hao Zhou, Jia Qian, Yu-Mei Xing, Long Cui, Yi-Feng Bu

“…Several rehabilitation methods have been used for patients after ACL surgery.ObjectiveThis study aimed to assess the overall efficacy of exercise therapy in improving outcomes for patients following ACL surgery using a systematic review and meta-analysis of randomized controlled trials (RCTs).Data sourcesPubMed, Web of Science, Embase, and the Cochrane Library were searched for randomized controlled trials published from 1 January 2000 to 30 August 2024. …”
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Intermittent enteral nutrition shortens the time to achieve nutritional goals in critically ill patients by Ondrej Hrdy, Kamil Vrbica, Jaroslav Duba, Martin Slezak, Eva Strazevska, Viktor Agalarev, Milos Duba, Radka Stepanova, Adam Svobodnik, Roman Gal

“…A total of 300 patients were randomized, and 294 were analyzed: 148 in the continuous arm and 146 in the intermittent arm. …”
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Definitions of Hemodynamic Instability Related to Renal Replacement Therapy in Critically Ill Patients: A Systematic Review Protocol by Jean Zhuo Wang, Lindsey Sikora, Peter Farrell, Swapnil Hiremath, Edward G. Clark

“…Objective: The primary objective of this proposed systematic review is to evaluate the association between HIRRT and clinical outcomes, as reported within randomized control trials in the literature. The secondary objective of this systematic review is to compare rates of HIRRT, according to various definitions used by randomized controlled trials, across different RRT modalities used to treat critically ill patients, with the goal of paving the way toward a common definition of HIRRT for future research. …”
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The effect of continuous positive airway pressure (CPAP) application on airway problems in pediatric patients with subglottic stenosis who undergo balloon dilatation by Zeliha Tuncel, Şenay Göksu, Özlem Deligöz, Kemal Tolga Saracoglu, Abdulatif Albasha, Bushra M. Abdallah, Ayten Saracoglu

“…Patients were randomized in a 1:1 ratio into the CPAP or non-CPAP group. …”
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Cannabis related side effects in otolaryngology: a scoping review by Jobanjit S. Phulka, Joel W. Howlett, Amanda Hu

“…Oxford Centre for Evidence-Based Medicine: Levels of Evidence and risk of bias using the Risk of Bias in randomized trials (RoB 2) and Risk of Bias in Non-Randomized Studies of Interventions (ROBINS-I) tools were assessed.. …”
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Exploring the Mechanism of Canmei Formula in Preventing and Treating Recurrence of Colorectal Adenoma Based on Data Mining and Algorithm Prediction by Xiaoling Fu, Yimin Xu, Xinyue Han, Xiangying Lin, Jingnan Wang, Guanhong Li, Xiaochen Fu, Min Zhang

“…After randomization, the patients were divided into a treatment group (receiving CMF granules) or a control group (receiving berberine hydrochloride tablets). …”
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Vascular Complications and Bleeding After Transfemoral TAVR With Surgical Versus Percutaneous Approach: A Contemporary Prospective Study by Annick Astié Dardaillon, Mariama Akodad, Fabien Huet, Pierre Alain Meunier, Thomas Gandet, Jean-Christophe Macia, Laurent Schmutz, Frederic Targosz, François Roubille, Matthieu Steinecker, Benoit Lattuca, Pierre Robert, Jean-Michel Berdeu, Guillaume Cayla, Florence Leclercq

“…SC may be considered when vascular access is anticipated as complex, but this strategy might be confirmed in a randomized study.…”
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Comparison of Once- with Twice-Daily Dosing of Fluticasone Propionate in Mild and Moderate Asthma by Louis-Philippe Boulet, Robert L Cowie, Roberto Dal Negro, Wade Brett, Milton Gold, Agostinho Marques, William S Thorburn, Nate M Stepner, Reid Bobson

“…OBJECTIVES: Two 12-week, randomized, double-blind, parallel-group studies were performed to compare the efficacy and safety of once- and twice-daily dosing of fluticasone propionate (FP) in the treatment of mild to moderate asthma, considered to require the equivalent of either 200 or 500 µg of FP daily.…”
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Evaluating the method reproducibility of deep learning models in biodiversity research by Waqas Ahmed, Vamsi Krishna Kommineni, Birgitta König-Ries, Jitendra Gaikwad, Luiz Gadelha, Sheeba Samuel

“…Our study shows that a dataset is shared in 50% of the publications; however, a significant number of the publications lack comprehensive information on deep learning methods, including details regarding randomness.…”
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A Clinical Trial to Investigate the Effect of Cynatine HNS on Hair and Nail Parameters by Christina Beer, Simon Wood, Robert H. Veghte

“…A new, novel product, Cynatine HNS, was evaluated for its effects as a supplement for improving various aspects of hair and nails in a randomized, double-blind, placebo-controlled clinical trial. …”
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Impact of Production Inputs and Timing on Crackness of Rice in Northern Ghana by Daniel Asomning Odoom, Joseph Xorse Kugbe, Israel Kwame Dzomeku, Albert Berdjour, Dennis Owusu Boateng, Richard Naabe Yaro, Prince Wireko, Ebenezer Kofi Sam, Philip Ghanney

“…The experiment was laid out in a randomized complete block design with three geographically distinct locations serving as replicates. …”
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The Prevalence of Glaucoma and Its Related Factors in Rural Residents: A Cross-Sectional Study in Jiangxi, China by Xiaojun Zhou, Qin Zhu, Jinglin Yi, Jiajunni Li, Qi Li, Jie Kuang, Yuanan Lu, Rui Zhou, Jiayan Chen

“…The cluster sampling method was used to randomly select six townships. Similarly, eight villages were randomly selected from each sample township. …”
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Activated Protein C Does Not Alleviate the Course of Systemic Inflammation in the APCAP Trial by Lea Kyhälä, Panu Mentula, Leena Kylänpää, Eeva Moilanen, Pauli Puolakkainen, Ville Pettilä, Heikki Repo

“…The study aimed to determine the effect of the activated protein C on the course of systemic inflammation in the APCAP (activated protein C in acute pancreatitis) trial where we randomized 32 patients with severe acute pancreatitis to receive either recombinant activated protein C (drotrecogin alfa activated) (n=16) or placebo (n=16) for 96 hours. …”
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