A Randomized Controlled Trial to Assess the Efficacy of Tiotropium in Canadian Patients with Chronic Obstructive Pulmonary Disease by Charles KN Chan, François Maltais, Chris Sigouin, Jennifer M Haddon, Gordon T Ford, on behalf of the SAFE Study Group

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A Comparison between Enriched and Nonenriched Enrollment Randomized Withdrawal Trials of Opioids for Chronic Noncancer Pain by Andrea D Furlan, Luis E Chaparro, Emma Irvin, Angela Mailis-Gagnon

“…An enriched enrollment randomized withdrawal (EERW) trial design has been advocated to be useful for the study of drugs that are beneficial to only a fraction of the individuals who take them. …”
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The role of Ashwagandha in modulating gut parameters in dogs—a randomized double-blind placebo-controlled trial by Kala Kumar Bharani, Ashok Kumar Devarasetti, Rajendar Bobbili, Amit Khurana, Donga Durga Veera Hanuman, Roupesh Gudepu, Swapna Guda

“…We hypothesized that ARE might promote a healthy gut by its adaptogenic and anti-inflammatory effects and improve vital parameters for healthy ageing.MethodsA randomized, double-blind, placebo-controlled trial was conducted in Telangana, India. …”
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Adaptive Just-in-Time Intervention to Reduce Everyday Stress Responses: Protocol for a Randomized Controlled Trial by Jillian A Johnson, Matthew J Zawadzki, Martin J Sliwinski, David M Almeida, Orfeu M Buxton, David E Conroy, David Marcusson-Clavertz, Jinhyuk Kim, Robert S Stawski, Stacey B Scott, Christopher N Sciamanna, Paige A Green, Emily M Repka, Meynard John L Toledo, Nicole L Sturges, Joshua M Smyth

“…After a 1-week run-in period, participants will be randomized into the JIT intervention or an active control condition for 2 weeks. …”
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The Effect of Low Carbohydrate Diet on Polycystic Ovary Syndrome: A Meta-Analysis of Randomized Controlled Trials by Xiaoshuai Zhang, Yang Zheng, Yanan Guo, Zhiwen Lai

“…Methods. Data from randomized controlled trials (RCTs) were obtained to perform a meta-analysis of the effects of LCD in PCOS patients. …”
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Causal associations between socioeconomic status and prostate cancer using two-sample Mendelian randomization study by Zhenxing Wang, Chunyan Wang, Xing Gou, Liang Pei, Xiaoyuan Qiao

“…Through two-sample Mendelian randomization (MR), this research seeks to assess the causal links between 4 genetically predicted SES indicators—average total household income before tax, the Townsend deprivation index at recruitment, unemployed status and college or university degree in the household—and PCa. …”
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The effect of dual-task training in older adults with total hip arthroplasty: a randomized controlled trial by İsmail Uysal, Fatih Özden, Mustafa Yalçın, Emir İbrahim Işık, Zübeyir Sarı

“…Methods Patients were randomized into the control group (CG) (n = 14) and intervention group (IG) (n = 14). …”
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Causal association between sarcopenia and chronic obstructive pulmonary disease: A two-sample Mendelian randomization by Jun Ma, Juanjuan Yao, Leyuan Zhang, Limin Tian

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The Effects of Physical Activity Feedback on Behavior and Awareness in Employees: Study Protocol for a Randomized Controlled Trial by Karen Van Hoye, Filip Boen, Johan Lefevre

“…We recruited 320 sedentary employees (age, 41.0 ± 10.7 years; BMI, 26.2 ± 4.2 kg/m2) to participate in the 12-month study. Participants were randomized into one of four intervention groups after being measured for 7 days and nights by means of the SWA: (1) a minimal intervention group received no feedback (MIG, ); (2) a pedometer group was provided only information on their daily step count (PG, ); (3) a display group received feedback on calories burned, steps taken, and minutes of physical activity by means of the SWA display (DG, ); (4) a coaching group also received the display and had weekly meetings with a Personal Coach (CoachG, ). …”
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Assessment of the efficacy of on-demand tegoprazan therapy in gastroesophageal reflux disease through a randomized controlled trial by Sun Hyung Kang, Hee Seok Moon, Jae Kyu Sung, Sun Moon Kim, Ki Bae Kim, Seung Woo Lee, Young Sin Cho, Ki Bae Bang, Kyung Ho Song

“…From six university hospitals in the Daejeon-Chungcheong region, we enrolled patients with GERD who had experienced symptomatic improvement with acid-suppressive therapy and, using a randomization table, randomly allocated these participants to two groups: to receive either tegoprazan 50 mg + esomeprazole placebo or tegoprazan placebo + esomeprazole 20 mg, respectively. …”
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Game theory and weight loss: Harmonic evidence from randomized controlled trials in Appalachia, KY and Jordan. by Daniel E Zoughbie, Dillon Huddleston, Eric L Ding

“…A workhorse model which has emerged for inferring players' strategies from their actions in finitely repeated games, is applied to data from randomized controlled trials conducted in Jordan and Kentucky; an attractive economic application portending substantive public health and other policy consequences. …”
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Ultra-small phospholipid nanoparticles in the treatment of combined hyperlipidemia: a randomized placebo-controlled clinical trial by Alexander Archakov, Valery Kukharchuk, Andrey Lisitsa, Elena Ponomarenko, Yulia Romashova, Tatiana Pleshakova, Elena Yarovaya, Vladimir Kutsenko, Maria Guseva, Valery Beregovykh, Olga Ipatova, Marina Zubareva, Elena Tikhonova, Sergei Ivanov, Farid Bedretdinov, Sergey Markin

“…Phospholipovit or placebo was randomly administered orally (500 mg) 2 times a day for 12 weeks. …”
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Effect of whole-body vibration combined with an exercise program in females with chondromalacia: A randomized controlled trial by Anwar Abdelgayed Ebid, Ali A. Elmonsif Thabet, Kadrya H Battecha, Abeer R Ibrahim, Hayam Mahmoud, Mohamed Mohamed Ibrahim Salem, Revan Salem Alammari, Farah Obaid Almuqati, Ghada Jameel Thiga, Maria Ahmad Alsaedi, Leen Khalid Bahamdain

“…This study employed a randomized controlled design with 40 healthy older female volunteers. …”
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A Prospective Randomized Study for Comparison of Modified Proximal Femoral Plate with Dynamic Hip Screw System by Jitendra Wadhwani, Ramchander Siwach, Himanshu Bansal, Roop Singh, Pradeep Kamboj, Hemant More

“…Aim: To conduct a prospective randomized study comparing the functional and radiological outcomes of dynamic hip screw (DHS) and modified proximal femoral locking compression plate (PFLCP) in Asian population with intertrochanteric fractures. …”
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Trace elements selenium and potassium are protective factors for cutaneous malignant melanoma: A Mendelian randomization study by Chen-Yu Li, Ai Zhong, Jun-Jie Chen

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A Randomized Trial of Ionic Silver Dressing to Reduce Surgical Site Infection After Gastrointestinal Surgery by Chihiro Kosugi, MD, Keiji Koda, MD, Hiroaki Shimizu, MD, Masato Yamazaki, MD, Kiyohiko Shuto, MD, Mikito Mori, MD, Akihiro Usui, MD, Hiroyuki Nojima, MD, Satoshi Endo, MD, Hiroo Yanagibashi, MD, Hidehito Arimitsu, MD, Toru Tochigi, MD, Tetsutaro Sazuka, MD, Mihono Hirota, MD, Hideyuki Kuboki, MD

“…Patients undergoing elective gastrointestinal surgery were randomly assigned to receive either Aquacel Ag Hydrofiber (study group) or film dressings (control group). …”
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Evaluating the Effectiveness of InsightApp for Anxiety, Valued Action, and Psychological Resilience: Longitudinal Randomized Controlled Trial by Victoria Amo, Falk Lieder

“…MethodsWe conducted a randomized controlled trial with 228 participants (completion rate: n=197, 86.4%; mean age 38, SD 11.50 years; age range 20-80 years; female: n=101, 52.6%; and White: n=175, 91.1%), who were randomly assigned to either the treatment or the active placebo control group. …”
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The Value of Ozone in CT-Guided Drainage of Multiloculated Pyogenic Liver Abscesses: A Randomized Controlled Study by Bing Li, Chuan Liu, Lang Wang, Yang Li, Yong Du, Chuan Zhang, Xiao-xue Xu, Han Feng Yang

“…The prospective study included 60 patients diagnosed with multiloculated PLA. All patients were randomly divided into two groups: catheter drainage alone (group I) and catheter drainage combined with ozone (group II). …”
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Evaluation of efficacy and safety of coenzyme Q10 in pediatric hemodialysis patients: a randomized controlled trial by Salma A. Rahman Sharaf, Sarah Farid Fahmy, Heba M. Adel Abou Zaghla, Ahmed Hussein Hassan, Sara Mahmoud Zaki

“…This was a prospective, randomized, double-blinded, placebo-controlled trial. …”
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The Efficacy of Chimeric Antigen Therapy in Viral Infectious Diseases: A Systematic Review of Randomized Controlled Trials by Hossein Hatami, Elnaz Ataei, Mohammadjavad Nasiri, Hamed Ghorani

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