Asymmetric Randomly Censored Mortality Distribution: Bayesian Framework and Parametric Bootstrap with Application to COVID-19 Data by Rashad M. EL-Sagheer, Mohamed S. Eliwa, Khaled M. Alqahtani, Mahmoud EL-Morshedy

“…This article investigates a survival analysis under randomly censored mortality distribution. From the perspective of frequentist, we derive the point estimations through the method of maximum likelihood estimation. …”
Get full text

A randomized controlled study of auricular point acupressure to manage chemotherapy-induced neuropathy: Study protocol. by Nada Lukkahatai, Michael V Nguyen, Jingyu Zhang, Yu-Min Cho, Chitchanok Benjasirisan, Heijingzi Monica Jia, Claudia M Campbell, Jennifer Kawi, Hulin Wu, Hongyu Wang, Rupsikha Bora, Johannes Thrul, Constance M Johnson, Thomas J Smith

“…<h4>Methods</h4>This is a three-arm randomized controlled clinical trial protocol. Patients aged 18 and older who are experiencing CIN are randomly assigned to one of the three groups: an APA group (in-person APA; mAPA), a sham control group (virtual APA; vAPA), and a wait-list usual care control group (UC). …”
Get full text

Effect of postpartum clinical guideline on maternal outcomes in iranian women: a randomized controlled clinical trial by Leila Abdoli Najmi, Sakineh Mohammad-Alizadeh-Charandabi, Shayesteh Jahanfar, Fatemeh Abbasalizadeh, Haniyeh Salehi Poormehr, Mojgan Mirghafourvand

“…Participants were randomly allocated to intervention and control groups. …”
Get full text

Low-Level Laser-Aided Orthodontic Treatment of Periodontally Compromised Patients: A Randomized Controlled Trial by Sachin B. Mangalekar, Ipsita Jayanti, Anurag Tiwari, Shobhit Saxena, Abhijith Ajith, Arun Vashisht, Naina Pattnaik

“…Materials and Methods: A randomized controlled trial was conducted with 60 periodontally compromised patients (mean age: 35 years). …”
Get full text

Pegilated interferon alpha 2b «Pegaltevir» chronic hepatitis C treatment (randomized clinical trial) by Marina V. Mayevskaya, Ye. N. Bessonova, P. O. Bogomolov, N. I. Geyvandova, K. V. Zhdanov, V. G. Morozov, V. D. Pasechnikov, I. Yu. Khomenko, A. V. Yagoda, V. T. Ivashkin

“…These qualities formed the basis for development of the Russian pegilated interferon-alpha 2b (Pegaltevir®, LLC «FARMAPARK», Russia) and carrying out doublestaged randomized open clinical trial: study of safety, tolerability and pharmacokinetics of Pegaltevir® at single injection of increasing doses in various groups of healthy volunteers - the I stage; studying of efficacy and safety of Pegaltevir® in comparison to PegIntron® (Schering-Plough, USA) at CHC as a part of double antiviral therapy with ribavirin (Rebetol®, Schering-Plough, USA) - the II stage. …”
Get full text

Randomized and Efficient Time Synchronization in Dynamic Wireless Sensor Networks: A Gossip-Consensus-Based Approach by Nan Xiong, Minrui Fei, Taicheng Yang, Yu-Chu Tian

“…This paper proposes novel randomized gossip-consensus-based sync (RGCS) algorithms to realize efficient time calibration in dynamic wireless sensor networks (WSNs). …”
Get full text

Alzheimer’s disease and antibody-mediated immune responses to infectious diseases agents: a mendelian randomization study by Jiayuan Zhang, Mingming Wang, Dong Wang, Linwen Deng, Yao Peng

Subjects: Get full text

Protein kinase inhibitors as targeted therapy for glioblastoma: a meta-analysis of randomized controlled clinical trials by José Pinto-Fraga, Celia García-Chico, Simone Lista, Pedro Miguel Lacal, Giuseppe Carpenzano, Maurizio Salvati, Alejandro Santos-Lozano, Grazia Graziani, Claudia Ceci

“…Upon disease progression, the anti-vascular endothelial growth factor-A (VEGF-A) monoclonal antibody bevacizumab, can be considered.Given the limited efficacy of pharmacological treatments, particularly for the recurrent disease, several molecularly targeted interventions have been explored, such as small-molecule protein kinase inhibitors (PKIs), inhibiting tyrosine kinase growth factor receptors and downstream signaling pathways involved in GBM angiogenesis and infiltrative behavior.This meta-analysis, based on searches in PubMed and Web Of Science, evaluated 12 randomized controlled trials (RCTs) examining PKIs in patients with newly diagnosed or recurrent GBM. …”
Get full text

Advantages and disadvantages of coronary drug-eluting stent: a 23-year journey of randomized clinical trials by Alfredo E. Rodriguez, Juan Mieres, Juan M. Rokos

Get full text

The Effect of auriculotherapy on sleep quality in children with attention deficit hyperactivity disorder: a randomized clinical trial by Laleh Mohammadi, Zahra Tagharrobi, Khadijeh Sharifi, Zahra Sooki, Mohammad Zare, Fatemeh Zare Joshaghani

“…Fifty-two eligible samples were selected using convenience sampling and randomly assigned to intervention and sham groups. …”
Get full text

Comparative efficacy of chemical peels and laser treatments in melasma: a meta-analysis of randomized controlled trials by Ingyu Lee, SeoWon Kang, JinHan Lee, Hyungin Cho, Ki Won Lee, Dongkeun Lim

Subjects: “…chemical peels; laser treatments; melasma; meta-analysis; post-inflammatory hyperpigmentation; randomized controlled trials…”
Get full text

Effects of Tocotrienol on Cardiovascular Risk Markers in Patients With Chronic Kidney Disease: A Randomized Controlled Trial by Liana Trugilho, Lívia Alvarenga, Ludmila Cardozo, Bruna Paiva, Jessyca Brito, Isis Barboza, Jonatas Almeida, Juliana dos Anjos, Pramod Khosla, Marcelo Ribeiro-Alves, Denise Mafra

“…This double-blind, placebo-controlled, randomized clinical trial aimed to evaluate the effects of a tocotrienol-rich fraction (TRF) supplementation (300 mg/day) on oxidative stress and inflammatory markers, including transcription factors in nondialysis (ND) and hemodialysis (HD) CKD patients for three months. …”
Get full text

Randomized Controlled Trial of Polyethylene Glycol versus Oral Sodium Phosphate for Bowel Preparation in Unsedated Colonoscopy by Dong Yang, Ke Tao, Geng Chen, Luping Zhang, Qingying He, Hong Xu

“…Between April 2019 and April 2020, a total of 586 outpatients scheduled for unsedated colonoscopy at the First Hospital of Jilin University (Changchun, China) were randomized into one of two groups, namely, the polyethylene glycol (PEG) group or the oral sodium phosphate solution (OSP) group. …”
Get full text

Association between Atopic Dermatitis and Dementia: Evidence from Systematic Review, Meta-analysis, and Mendelian Randomization by Yeon-Su Gwak, Seo-Yeon Kim, Chae-Eon Woo, Kihyuk Shin, Eunjeong Son, Jin-Woo Kim, Sung-Jin Kim, Tae-Jin Song, Hae Ryoun Park, Kihun Kim, Dai Sik Ko, Yun Hak Kim

Subjects: Get full text

Randomized controlled trial of the efficacy of attention and emotional regulation training for children with attention deficit hyperactivity disorder by YANG Letian, HONG Danping, DANG Caiping, ZHU Zhihang, HU Yingzi, PENG Kaiqi, XU Yixuan, LIU Jinlan, YANG Chanjuan, CHENG Daomeng, YU Meng, YIN Weizhen

Subjects: “…attention deficit hyperactivity disorder|emotional regulation training|attention training|psychological and social intervention|randomized controlled trial…”
Get full text

Trabeculectomy and EX-PRESS Implantation in Open-Angle Glaucoma: An Updated Meta-Analysis of Randomized Controlled Trials by Yi Sun, Bowen Zhang, Rouxi Zhou, Tao Wang, Juan Deng

“…Thus, we conducted the updated meta-analysis to clarify the issue. Methods. Randomized controlled trials (RCTs) were selected through search of databases PubMed, Web of Science, Embase, and the Cochrane Library from their inception up until November 2018. …”
Get full text

Metformin versus insulin in glycemic control in pregnancy (MevIP): a randomized clinical trial protocol by Carolina Freitas Alves Amaral-Moreira, Daiane Sofia Morais Paulino, Belmiro G. Pereira, Patricia Moretti Rehder, Fernanda G. Surita

“…Methods We designed an open randomized controlled trial comparing two treatments for pregnant women with type II diabetes mellitus (DM) and gestational diabetes (DMG): the metformin group (intervention) and the insulin group (as a routine service). …”
Get full text

The impact of visual fidelity on screen-based virtual reality food choices: A randomized pilot study. by Bianca Curi Braga, Pejman Sajjadi, Mahda Bagher, Alexander Klippel, Jessica Menold, Travis Masterson

“…<h4>Intervention</h4>Participants were randomly assigned to either a high- (n = 43) or a low- (n = 41) visual fidelity environment and were asked to select foods to have a meal with a friend.…”
Get full text

Screening for Hypertension in adolescents living with HIV: Protocol for a cluster randomized trial to improve guideline adherence. by Raphael Adu-Gyamfi, Juliana Enos, Kwame Yeboah, Veronika Shabanova, Nicola Hawley, Deda Alangea Ogum, Adwoa Agyei Nkansah, Elijah Paintsil, Kwasi Torpey

“…<h4>Methods</h4>A multi-facility cluster-randomized study will be conducted. The clusters will be 20 antiretroviral therapy sites in the Greater Accra Region of Ghana with the highest adolescent caseload. …”
Get full text

Modeling and simulations of hydrodynamic shocks in a plasma flowing across randomized ICF scale laser beams by Hüller, S., Ludwig, J. D. T., Rose, H. A., Bruulsema, C., Farmer, W., Michel, P., Milder, A. L., Swadling, G. F., Rozmus, W.

“…Numerical simulations with beams that are smoothed by spectral dispersion compare well with the linear theory results, diverging from those produced by beams with only a random phase plates in the nonlinear regime. The conditions necessary for shock generation and their effects on the laser plasma coupling in inertial confinement fusion (ICF) experiments are also discussed.…”
Get full text