A scoping review of randomized trials assessing the impact of n-of-1 trials on clinical outcomes. by Joyce P Samuel, Susan H Wootton, Travis Holder, Donald Molony

“…We abstracted elements related to study design and results and assessed risk of bias for both the overall randomized trials and the n-of-1 trials. The review was registered on PROSPERO. …”
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Efficacy of aquatic exercises on balance in children with sickle cell anemia: A randomized controlled trial by Omar Abd El-Hameed Abd El-Fattah Ghetas, Azza Abd El-Aziz Abd El-Hady, El-Sayed Ali Shaheen Ali, Amira El-Sayed El-Bagalaty

“… The aim of this study was to investigate the efficacy of aquatic exercises on balance in children with sickle cell anemia. A randomized controlled trial was conducted. Sixty children with mild sickle cell anemia and poor balance from both sexes (35 boys and 25 girls) participated in this study. …”
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Causal Association Between Obstructive Sleep Apnea and Migraine: A Bidirectional Mendelian Randomization Study by Wang YP, Wei HX, Hu YY, Zhang C, Niu YM

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Intervention for Social Frailty Focusing on Physical Activity and Reducing Loneliness: A Randomized Controlled Trial by Gen A, Higuchi Y, Ueda T, Hashimoto T, Kozuki W, Murakami T, Ishigami M

“…Participants were randomly assigned to either the intervention (n = 34) or the control (n = 30) group. …”
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Application of S-100 absorbable hemostatic patch in endonasal endoscopic dacryocystorhinostomy: A randomized controlled trial by Hai-Sheng Zheng, Xing-Wu Zhong, Jia-Yao Xu, Hai-Yan Chen, Li-Na Liu, Bo-Wen Ou-Yang

“…Methods: Two hundred and twenty-six patients with unilateral chronic dacryocystitis (CD) were randomly divided into two groups in a randomized controlled trial: the S-100 absorbable hemostatic patch group (group A) and the control group (group B). …”
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Effect of life skills training by a midwife on pregnancy anxiety: A randomized controlled trial by Fatemeh Hassanpour, Mozhgan Javadnoori, Elham Maraghi, Fariba Zargar Shirazi

“…Materials and Methods: This randomized controlled trial was conducted in Abadan, Iran, in 2020. …”
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Causal Relationships Between Leukocyte Subsets and Adverse Fetal Outcomes: A Mendelian Randomization Study by Hong Chen, Li-Zhen Shao, Ying-Xiong Wang, Zhi-Jie Han, Yong-Heng Wang, Xia Li, Jing-Yu Chen, Tai-Hang Liu

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Augmented Reality in Enhancing Operating Room Crisis Checklist Adherence: Randomized Comparative Efficacy Study by Rayan Ebnali Harari, Abdullah Altaweel, Erik Anderson, Charles Pozner, Rafael Grossmann, Andrew Goldsmith, Hamid Shokoohi

“…MethodsThis study was a randomized comparative efficacy study comparing the utility of AR checklists, paper checklists, and no checklist scenarios using 4 validated and simulated OR crises scenarios: asystolic cardiac arrest, air embolism, unexplained hypotension/hypoxia, and malignant hyperthermia. …”
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Nurse management of minor problems in primary care emergencies: a non-randomized controlled trial by Jordi Estarlich-Corominas, Neus Soler-Abril, Anna Casanellas-Chuecos, Sara Becerra-Corzo, Andrea Sofia Bianco, Pere Torán-Monserrat, Rosa García-Sierra

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Efficacy of acupuncture for primary osteoporosis: a systematic review and meta-analysis of randomized controlled trials by Tianyi Ma, Tiantian Zhang, Le Zhang, Haoming Zhao, Ke Liu, Jianjun Kuang, Liang Ou

“…Data were synthesized using a random-effects meta-analysis model, and the observed heterogeneity was investigated using subgroup analyses. …”
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Bromhexine Hydrochloride Prophylaxis of COVID-19 for Medical Personnel: A Randomized Open-Label Study by Evgeny N. Mikhaylov, Tamara A. Lyubimtseva, Aleksandr D. Vakhrushev, Dmitry Stepanov, Dmitry S. Lebedev, Elena Yu. Vasilieva, Alexandra O. Konradi, Evgeny V. Shlyakhto

“…In a single-centre randomized open-label study, medical staff managing patients with suspected and confirmed COVID-19 were enrolled and followed up for 8 weeks. …”
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Family participatory clown therapy in venipuncture in hospitalized children: A non-randomized controlled trial. by Tianyu Chen, Qiying Chen, Zhenhua Lin, Jingfang Ye

“…<h4>Methods</h4>We recruited 104 children aged 3 to 6 years for a non-randomized controlled trial from March to December 2022. …”
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Vitamin C–Based Gingival Depigmentation Versus Surgical Depigmentation: A Randomized Clinical Trial by Aehad Ul Haque, Nand Lal, Shalini Kaushal, Pavitra Rastogi, Rameshwari Singhal

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Investigating the correlation of hip circumference to cardiovascular disease and type‐2 diabetes using Mendelian randomization by Hongtao Liu, Zhaoyu Li, Su Yan, Shaopeng Ming

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Randomized Controlled Trial of Laparoscopic versus Open Radical Cystectomy in a Laparoscopic Naïve Center by Waleed Mohamed Fadlalla, Ayman Hanafy, Mahmoud Abdelhakim, Hatem Aboulkassem, El Sayed Ashraf, Ahmed Abdelbary

“…Methodology. This is a randomized controlled trial comparing laparoscopic radical cystectomy (LRC) to open radical cystectomy (ORC) at a single institute. …”
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Experimental hypothermia by cold air: a randomized, double-blind, placebo-controlled crossover trial by Ane M. Helland, Sigurd Mydske, Jörg Assmus, Guttorm Brattebø, Øystein Wiggen, Haakon K. Kvidaland, Øyvind Thomassen

“…The between-groups difference was assessed using analysis of covariance (ANCOVA) with left censoring (Tobit model) and individual random intercept. Secondary outcomes were trajectory of core temperature and reduction of shivering. …”
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Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country by Samarendra Mahapatro, Nijwm Mahilary, Amit Kumar Satapathy, Rashmi Ranjan Das

“…This double-blind, randomized trial was designed to study the role of nitazoxanide in acute rotavirus diarrhea. …”
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Exploring the Mechanisms of Zhenbao Pills in the Treatment of Stroke through Network Pharmacology Combined with Mendelian Randomization by Yanhong Liu, Yunqi Hua, Xiaoe Jia

“…We also used Mendelian randomization (MR) to assess causal relationships between feature genes and stroke incidence, for which colocalization was employed for validation. …”
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Response to Statin Therapy in Obstructive Sleep Apnea Syndrome: A Multicenter Randomized Controlled Trial by Marie Joyeux-Faure, Renaud Tamisier, Jean-Philippe Baguet, Sonia Dias-Domingos, Stephen Perrig, Georges Leftheriotis, Jean-Paul Janssens, Wojciech Trzepizur, Sandrine H. Launois, Françoise Stanke-Labesque, Patrick A. Lévy, Frédéric Gagnadoux, Jean-Louis Pepin

“…Results. 51 severe OSA patients were randomized. Key demographics for the study population were age 54 ± 11 years, 21.6% female, and BMI 28.5 ± 4.5 kg/m2. …”
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Extracorporeal Hemadsorption versus Glucocorticoids during Cardiopulmonary Bypass: A Prospective, Randomized, Controlled Trial by Gordana Taleska Stupica, Maja Sostaric, Marija Bozhinovska, Lea Rupert, Zoran Bosnic, Ales Jerin, Alojz Ihan, Tomislav Klokocovnik, Matej Podbregar

“…Seventy-six patients with prolonged CPB were recruited and randomized, with 60 included in final analysis. Allocation was into three groups: Methylprednisolone (n = 20), Cytosorb (n = 20), and Control group (usual care, n = 20). …”
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