Effect of Weight-Loss Diet Combined with Taurine Supplementation on Fasting Levels of Fibroblast Growth Factors19, 21, and 𝛃-klothoCo-Receptor in Obese Women: A Randomized Clinical Trial by Maryam Asadi, Fatemeh Haidari, Hossein Bavi Behbahani, Maryam J Chitsazi, Javad Mohammadi-asl, Kambiz Ahmadi-Angali

“…This study is the first randomized controlled trial to assess the effectiveness of a Tau supplement in combination with a weight loss intervention on fibroblast growth factors (FGF) 19, 21, and β-Klotho co-receptor in obese women. …”
Get full text

Supervised pulmonary tele-rehabilitation and individualized home-based pulmonary rehabilitation for patients with COPD, unable to participate in center-based programs. The protocol for a multicenter randomized controlled trial - the REPORT study by Christina Nielsen, Nina Godtfredsen, Stig Molsted, Charlotte Ulrik, Thomas Kallemose, Henrik Hansen

Get full text

Evaluation of preemptive pregabalin efficacy on block characteristics and postoperative analgesia in patients undergoing infra-umbilical surgeries under spinal anesthesia: A prospective randomized double-blind placebo controlled study by Indira Kumari, Swati Dhania, Surendra Kumar Sethi, Santosh Choudhary, Ipra Jain, Vidhu Yadav

“…Materials and Methods: Seventy patients American Society of Anesthesiologists physical status I and II, posted for infra-umbilical surgeries under spinal anesthesia, were randomly allocated into two groups. Group P (n = 35) received preemptive oral pregabalin 150 mg and Group C (n = 35) received placebo, 1 h before surgery. …”
Get full text

A randomized, double-blind, Phase 1, single- and multiple-dose placebo-controlled study of the safety and pharmacokinetics of IN-006, an inhaled antibody treatment for COVID-19 in healthy volunteersResearch in context by Thomas R. Moench, Lakshmi Botta, Brian Farrer, Jason D. Lickliter, Hyunah Kang, Yoona Park, Cheolmin Kim, Marshall Hoke, Miles Brennan, Morgan D. McSweeney, Zachary Richardson, John B. Whelan, Jong Moon Cho, Soo Young Lee, Frances Faurot, Jeff Hutchins, Samuel K. Lai

“…The ratio of active:placebo randomization to each cohort was set at 3:1. The primary outcomes were safety and tolerability. …”
Get full text

Findings from the Tushirikiane-4-MH (supporting each other for mental health) mobile health–supported virtual reality randomized controlled trial among urban refugee youth in Kampala, Uganda by Carmen H. Logie, Moses Okumu, Zerihun Admassu, Frannie MacKenzie, Lesley Gittings, Jean-Luc Kortenaar, Naimul Khan, Robert Hakiza, Daniel Kibuuka Musoke, Aidah Nakitende, Brenda Katisi, Peter Kyambadde, Richard Lester, Lawrence Mbuagbaw

“…We examined the effectiveness of VR in reducing depression with urban refugee youth in Kampala, Uganda. This randomized controlled trial assessed VR alone (Arm 1), VR followed by Group Problem Management Plus (GPM+) (Arm 2) and a control group (Arm 3), with a peer-driven and convenience sample of refugee youth aged 16–25 in Kampala. …”
Get full text

Randomized, observer-blind, controlled Phase 1 study of the safety and immunogenicity of the Na-GST-1/Alhydrogel hookworm vaccine with or without a CpG ODN adjuvant in hookworm-naïve adults. by David J Diemert, Maria Zumer, Mark Bova, Christina Gibbs-Tewary, Elissa M Malkin, Doreen Campbell, Lara Hoeweler, Guangzhao Li, Maria Elena Bottazzi, Peter J Hotez, Jeffrey M Bethony

“…In each cohort of 12 participants, 4 were randomized to receive 100 µg of Na-GST-1/Alhydrogel and 8 to receive 30 µg or 100 µg of Na-GST-1/Alhydrogel plus the Cytosine-phospho-Guanine (CpG) oligodeoxynucleotide Toll-like receptor-9 agonist, CpG 10104, in the first and second cohorts, respectively. …”
Get full text

Angiographic Restenosis in Coronary Bifurcations Treatment with Regular Drug Eluting Stents and Dedicated Bifurcation Drug-Eluting BiOSS Stents: Analysis Based on Randomized POLBOS I and POLBOS II Studies by Robert J. Gil, Jacek Bil, Adam Kern, Luis A. Iñigo-Garcia, Radoslaw Formuszewicz, Slawomir Dobrzycki, Dobrin Vassilev, Roxana Mehran

Get full text

Modulating delirium through stimulation (MoDeSt): study protocol for a randomized, double-blind, sham-controlled trial assessing the effect of postoperative transcranial electrical stimulation on delirium incidence by Sophie Leroy, Viktor Bublitz, Ulrike Grittner, Robert Fleischmann, Falk von Dincklage, Daria Antonenko

“…Methods We will perform a randomized, double-blind, sham-controlled trial using single-session postoperative application of tES in the recovery room in 225 patients (> 65 years) undergoing elective major surgery. …”
Get full text

Combination of Compound Kushen injection with first-line treatment versus first-line treatment alone for advanced colorectal cancer: a study protocol for a multicenter, openlabel, randomized controlled trial by Jingyuan Wu, Yuansha Ge, Guanghui Zhu, Ruike Gao, Xiaoyu Zhu, Ying Zhang, Jie Li

Subjects: Get full text

Integration of Mendelian Randomization to explore the genetic influences of pediatric sepsis: a focus on RGL4, ATP9A, MAP3K7CL, and DDX11L2 by Liuzhao Zhang, Quanwang Chu, Shuyue Jiang, Bo Shao

Subjects: Get full text

Efficacy of Ma'aljobon Aftimouni (Cuscuta Reflexa and whey) on HbA1c and blood glucose levels in patients with Type 2 Diabetes: A randomized triple-blind clinical trial by Fatemeh Mehrabi, Ali Safdari, Azam Moslemi, Mehdi Salehi, Ali Agharazi, Mohammad Reza Rezvanfar

“…In this regard, patients with inclusion criteria were randomly divided into three groups Ma'aljobon with Aftimoun (n = 34), Ma'aljobon without Aftimoon (n = 34), and the control group (n = 34). …”
Get full text

Supervised pulmonary tele-rehabilitation and individualized home-based pulmonary rehabilitation for patients with COPD, unable to participate in center-based programs. The protocol for a multicenter randomized controlled trial - the REPORT study. by Christina Nielsen, Nina Godtfredsen, Stig Molsted, Charlotte Ulrik, Thomas Kallemose, Henrik Hansen

“…<h4>Materials and methods</h4>This study is a multicenter randomized controlled trial consisting of three parallel groups; PTR, HPR and a control group. 180 patients with moderate to very severe COPD, who are unable to attend in center-based PR programs will be included. …”
Get full text

A prospective, randomized, single-center, two-arm, open-label study to evaluate the efficacy of biotherapi®, a two-strain bacillus probiotic blend, as an adjunctive therapy in the treatment of rheumatoid arthritis by Arindam Nandy Roy, Yarram Ashok Kumar, Syeda Sana Fatima

“…Methods: In this prospective, randomized, single-center, two-arm, open-label study, patients were randomized (1:1) to receive twice-daily adjunctive Biotherapi® (n = 125) or standard of care alone (n = 125) for 12 weeks. …”
Get full text

Classification of female MDD patients with and without suicidal ideation using resting-state functional magnetic resonance imaging and machine learning by Morteza Fattahi, Milad Esmaeil-Zadeh, Hamid Soltanian-Zadeh, Hamid Soltanian-Zadeh, Hamid Soltanian-Zadeh, Reza Rostami, Jamil Mansouri, Gholam-Ali Hossein-Zadeh, Gholam-Ali Hossein-Zadeh

Subjects: Get full text

Application of machine learning in the fake user identification of IoT by Rongfang ZHANG, Dandan XU, Yuanguang WANG, Siyu PAN, Zhengmao LI

Subjects: Get full text

An AI recognition method for children's clinical operative pain by skin potential (SP) signal by Mingxuan Huang, Cangcang Fu, Linbo Chui, Jiadong He, Xiaozhi Wang, Jikui Luo, Bin Wu, Yonggang Chen, Shaohua Hu, Jihua Zhu, Yubo Li

Subjects: Get full text

Geospatial digital mapping of soil organic carbon using machine learning and geostatistical methods in different land uses by Yahya Parvizi, Shahrokh Fatehi

Subjects: Get full text

Establishment and Evaluation of Atmospheric Water Vapor Inversion Model Without Meteorological Parameters Based on Machine Learning by Ning Liu, Yu Shen, Shuangcheng Zhang, Xuejian Zhu

Subjects: Get full text

From Net Topology to Synchronization in HR Neuron Grids by Stefano Cosenza, Paolo Crucitti, Luigi Fortuna, Mattia Frasca, Manuela La Rosa, Cecilia Stagni, Lisa Usai

Subjects: Get full text

Multi-Strategy Improved Whale Optimization Algorithm and Its Engineering Applications by Yu Zhou, Zijun Hao

Subjects: Get full text