A prospective randomized controlled trial comparing biphasic cartilage repair implant with microfracture in small chondral lesions of knee: findings at five-year-follow-up by Yao-Yi Kuo, Si-Qi Chiu, Wen-Pei Chang, Chih-Yu Chen, Chih-Hwa Chen, Chen-Kun Liaw, Cheng-Aun Tan, Pei-Wei Weng

“…They were randomized to either the BiCRI (n = 11) or microfracture (n = 10) treatment groups. …”
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Effectiveness of Electronic Quality Improvement Activities to Reduce Cardiovascular Disease Risk in People With Chronic Kidney Disease in General Practice: Cluster Randomized Trial With Active Control by Jo-Anne Manski-Nankervis, Barbara Hunter, Natalie Lumsden, Adrian Laughlin, Rita McMorrow, Douglas Boyle, Patty Chondros, Shilpanjali Jesudason, Jan Radford, Megan Prictor, Jon Emery, Paul Amores, An Tran-Duy, Craig Nelson

“…MethodsGeneral practices recruited through practice-based research networks in Victoria and Tasmania were randomly allocated 1:1 to the FHT CKD module or active control. …”
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Comparison of Clinical and Radiographic Success between MTA and Biodentine in Pulpotomy of Primary Mandibular Second Molars with Irreversible Pulpitis: A Randomized Double-Blind Clinical Trial by Alireza Eshghi, Maryam Hajiahmadi, Mohammad Hossein Nikbakht, Mona Esmaeili

“…This study was conducted as a randomized double-blind clinical trial. Participants were selected according to inclusion criteria and 52 samples were randomly selected using random numbers table in group A. …”
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Effect of Reablement Strategies targeting Sarcopenia (ReStart-S) on sarcopenic older adults residing in long term care settings: A protocol for cluster randomized trial by Prabal Kumar, Shashikiran Umakanth, Olivier Bruyère, Girish N

“…Methods: The study is a cluster randomized trial that will take place in LTCS. A total of 78 sarcopenic older adults will be included, selected through convenience sampling, and diagnosed using the Asian Working Group for Sarcopenia 2019 criteria. …”
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Effectiveness of a Virtual Reality Serious Video Game (The Secret Trail of Moon) for Emotional Regulation in Children With Attention-Deficit/Hyperactivity Disorder: Randomized Clinical Trial by Marina Martin-Moratinos, Marcos Bella-Fernández, María Rodrigo-Yanguas, Carlos González-Tardón, Chao Li, Ping Wang, Ana Royuela, Pilar Lopez-Garcia, Hilario Blasco-Fontecilla

“…MethodsThis was a prospective, unicentric, randomized, unblinded, pre- and postintervention study with block-randomized sequence masking. …”
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Effects of Dexmedetomidine Infusion on Inflammatory Responses and Injury of Lung Tidal Volume Changes during One-Lung Ventilation in Thoracoscopic Surgery: A Randomized Controlled Trial by Chun-Yu Wu, Yi-Fan Lu, Man-Ling Wang, Jin-Shing Chen, Yen-Chun Hsu, Fu-Sui Yang, Ya-Jung Cheng

“…Sixty patients were randomly assigned to receive dexmedetomidine or saline during thoracoscopic surgery. …”
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Preoperative Analgesia Efficacy of Liposomal Bupivacaine Following Pericapsular Nerve Group (PENG) Block in Patients with Hip Fracture: A Randomized Controlled Observer-Blinded Study by Haobin Peng, Jiajun Wen, Manli Chen, Zhengyuan Xia, Ying Jiang, Kaiqi Xie, Weitao Huang, Bangsheng Cui, Peixing Li, Yiwen Zhang, Xianping Wu

“…This single-center, randomized controlled, observer-blinded trial utilizes a novel combination of liposomal bupivacaine (LB) single-injection PENG block to examine its efficacy, duration, and safety in preoperative analgesia for hip fractures, aiming to develop a new preoperative analgesic protocol. …”
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Couple-Based Intervention to Improve HIV Care Engagement for Women and their Partners in KwaZulu-Natal, South Africa: Outcomes of a Pilot Randomized Controlled Trial by Jennifer M. Belus PhD, Alastair van Heerden PhD, Abigail C. Hines MPH, Thembelihle P. Pita MCom, Yvonne Mdakane MSS, Jessica F. Magidson PhD, Heidi van Rooyen PhD, Ruanne V. Barnabas MBChB, PhD

“…Twenty couples were randomized (1:1) to either START Together, a five-session manualized behavioral intervention, or treatment as usual, adherence counseling referral. …”
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Comparison of analgesic efficacy of topical tramadol versus topical lidocaine in the control of postoperative pain in children after tonsillectomy: A randomized double-blinded clinical trial by Abdelwahab A. Saleh, Abdelfattah M. Abdelfattah

“…Patients and methods This prospective, randomized, double blind, controlled clinical study included 80 children, aged 4–15 years. …”
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Correction: Comparing different montages of transcranial direct current stimulation on dual-task walking and cortical activity in chronic stroke: double-blinded randomized controlled trial by Pei‑Ling Wong, Yea‑Ru Yang, Shun‑Chang Tang, Shih-Fong Huang, Ray‑Yau Wang

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A comparison between the effect of Oral Melatonin and Hydroxyzine for preventing preoperative Anxiety in Pediatric Patients undergoing Adenotonsillectomy: A randomized, double-blinded controlled study by Sarah Omar Mousa, Amany Khairy Abo El Hussien, Gehad Hanafy Abdalgaliel

“…Patients and methods: In a randomized, double-blinded, prospective study, 90 children of both sexes aged 3 to 10, were divided into three equal groups, all the patients received 10 ml of apple juice 2 hours preoperatively. …”
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Comparison of Effect Sevoflurane-Based Anesthesia and Propofol-Based Anesthesia on the Early Postoperative Renal Function of Living Kidney Transplant Donors: A Randomized Controlled Trial by Cai J, Kang F, Han M, Huang X, Yan W, Wan F, Li J

“…The impact of anaesthetics on postoperative biomarkers of renal injury in living kidney transplant donors is not well understood.Patients and Methods: 70 transplant donors who underwent kidney extraction were randomly assigned to following two groups: sevoflurane (S group) and propofol (P group). …”
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Zinc absorption from maize-based meals enriched with edible house crickets: a randomized crossover stable-isotope study in Kenyan pre-school children by Nikolin Hilaj, Tele Boit, Pauline Andang’o, Christophe Zeder, Martin N. Mwangi, Marijke Hummel, Ornella Necochea Velazco, Joop J. A. van Loon, Marcel Dicke, Michael B. Zimmermann, Alida Melse-Boonstra

“…For this, children were randomized to consume two different experimental meals labeled with stable isotopes of zinc (Zn) at two different days, separated by a wash-out period of one month. …”
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Effect of Dexmedetomidine on the ED50 and ED95 of Sufentanil in Patient-Controlled Intravenous Analgesia After Cesarean Section: A Randomized, Controlled, Double-Blind Trial by Li J, Fu W, Wang N, Zeng S, Li X, Wan J, Wang F

“…Jiabei Li,1,2 Wuchang Fu,3 Na Wang,1 Sisi Zeng,1 Xuechao Li,1 Jixiang Wan,1 Fangjun Wang1 1Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, People’s Republic of China; 2Department of Anesthesiology, Meishan City People’s Hospital, Meishan, People’s Republic of China; 3Department of Anesthesiology, The Second Clinical Medical College of North Sichuan Medical College (Nanchong Central Hospital), Nanchong, People’s Republic of ChinaCorrespondence: Fangjun Wang, Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, No. 1 Maoyuan South Road, Nanchong, Sichuan, 637000, People’s Republic of China, Tel +86 13458253172, Email wfjlxy006@126.comPurpose: To determine the effect of dexmedetomidine on the ED50 and ED95 of sufentanil in patient-controlled intravenous analgesia (PCIA) after cesarean section.Patients and Methods: Parturients who underwent elective cesarean section (n = 80) were randomly assigned to either the sufentanil group (S group) or the dexmedetomidine-sufentanil combination group (DS group). …”
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Impact of the initiation of isCGM soon after type 1 diabetes mellitus diagnosis in adults on glycemic indices and fear of hypoglycemia: a randomized controlled trial by Jerzy Hohendorff, Jerzy Hohendorff, Agata Grzelka-Wozniak, Marta Wrobel, Michal Kania, Michal Kania, Lidia Lapinska, Dominika Rokicka, Dorota Stoltny, Irina Kowalska, Krzysztof Strojek, Dorota Zozulinska-Ziolkiewicz, Maciej T. Malecki, Maciej T. Malecki

“…Main secondary outcomes included changes in mean glucose and time in range (TIR) from baseline to 4 weeks after randomization.ResultsThe full analysis set included 23 patients (12 from the intervention group and 11 from the control group), aged 25.6 ± 5.1 years (14 men, 9 women). …”
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Comparative effectiveness of physical activity interventions on cognitive functions in children and adolescents with Neurodevelopmental Disorders: a systematic review and network meta-analysis of randomized controlled trials by Ruiyuan Tao, Yijian Yang, Mark Wilson, Jeremy R. Chang, Chang Liu, Cindy H. P. Sit

“…Results Thirty-one randomized controlled trials (n = 1,403, mean age 10.0 ± 1.9 years) with 66 arms were included in the network. …”
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Modulation of hormonal, metabolic, inflammatory and oxidative stress biomarkers in women with polycystic ovary syndrome following combined (resistant and endurance) training: a randomized controlled trail by Masoud Nasiri, Amirabbas Monazzami, Solmaz Alavimilani, Zatollah Asemi

“…We evaluated the function of combined (COM) training on metabolic, hormonal parameters, and biomarkers of oxidative stress and inflammation in PCOS patients. Methods This randomized controlled clinical trial was conducted on 30 women with PCOS divided (age: 23.8 ± 5.3 years, height:162.8 ± 4.9 cm, weight: 82.4 ± 9.7 kg, body mass index: 30.3 ± 3.9 kg/m2) into two groups to receive COM training intervention (n = 15) or control group (n = 15) for eight weeks. …”
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Miniperc percutaneous nephrolithotomy versus retrograde intrarenal surgery in the treatment of juxta uretero-pelvic junction upper ureteric calculi: A prospective, randomized control study by T. P. Pradhyumna Koushik, Vivek Meyyappan, Nakul Baban Aher, Hariharasudhan Sekar, Gayathri Thiruvengadam, Sriram Krishnamoorthy

“…Materials and Methods: A prospective, randomized study was done on 100 patients with upper ureteric stones up to 2 cm in size and within 2 cm from PUJ. …”
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Efficacy and Safety of Murivenna Anal Infiltration Compared to Diltiazem Topical Application in Chronic Anal Fissure: Protocol for a Prospective, Randomized, Open-Label Clinical Trial by Pratap Shankar KM, Indu Puthan Purayil, Palengara Binitha, Amit Kumar Rai, Sophia Jameela, Azeem Ahmad, Chandra Sekhara Rao Bhogavalli, Narayanam Srikanth, Rabinarayan Acharya

“…MethodsThis is an open-labeled, randomized, controlled parallel group clinical trial with a sample size of 66 participants to be randomized and allocated in a 1:1 ratio to 2 groups. …”
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Role of adductor canal block and genicular nerve block on postoperative pain and enhanced recovery in patients undergoing total knee arthroplasty: A randomized clinical trial by Bassel Mohammed Elfokery, Mustafa Seet, Tareef Ashour, Hatem Alharbi, Mujeeb Ashraf, Hatim Alshareef, Mohammad Nyaz, Rayan Bakhreba, Atif Sait

“…Patients and Methods: This randomized trial was conducted on 50 subjects aged 40–75 years who underwent TKA under spinal anesthesia. …”
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