Effects of melatonin supplementation on oxidative stress, and inflammatory biomarkers in diabetic patients with chronic kidney disease: a double-blind, randomized controlled trial by Sara Sadeghi, Amirahmad Nassiri, Monir Sadat Hakemi, Fatemeh Hosseini, Fatemeh Pourrezagholie, Fatemeh Naeini, Aylar Nadiri Niri, Hossein Imani, Hamed Mohammadi

“…For ten weeks, participants were randomized to receive either a placebo or 5 mg of melatonin twice a day. …”
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Direct superior approach versus posterolateral approach in mid-term clinical outcomes of total hip arthroplasty: a prospective randomized controlled study by Zhanqi Wei, Yiming Xu, Wei Zhu, Xisheng Weng, Bin Feng

“…Results Thirty three patients were randomized to the PLA group and 32 patients allocated to the DSA group. …”
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Effects of a nutrition education intervention on nutrition knowledge and attitude among overweight and obese primary schoolchildren: a cluster randomized controlled trial by Rusidah Selamat, Nur Azlina Abdul Aziz, Junidah Raib, Norlida Zulkafly, WNurul Ashikin W. Mohamad, Ainan Nasrina Ismail, Muhammad Yazid Jalaludin, Fuziah Md. Zain, Zahari Ishak, Abqariyah Yahya, Abdul Halim Mokhtar

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Effect of E-learning clinical management of substance-dependent pregnant women on the knowledge and clinical skill performance of midwives: a randomized controlled trial by Hasti Heidarian, Manoosh Mehrabi, Parvin Ghaemmaghami, Roksana Janghorban

“…One hundred midwives working in governmental maternity hospitals were recruited and randomly assigned to the intervention (n = 50) or control (n = 50) group through blocked randomization. …”
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The potential of gardening and other plant‐related interventions to reduce symptoms of depression: A systematic review of non‐randomized controlled trials and uncontrolled studies by Claudio D. Rosa, Talisson S. Chaves, Silvia Collado, Lincoln R. Larson, KangJae Jerry Lee, Christiana C. Profice

“…., taking care of plants, planting, gardening) on individuals' depressive symptoms through analyses focused exclusively on randomized controlled trials, but that approach overlooks a majority of the potentially informative published research. …”
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The Combined Effect of Multisensory Stimulation and Therapist Support on Physical and Mental Health of Older Adults Living in Nursing Homes: Pilot Randomized Controlled Trial by Sewar Khatib, Yuval Palgi, Yoni K Ashar, Natalya Polyvyannaya, Pavel Goldstein

“…MethodsA total of 96 patients aged 65-99 years from a nursing home were randomly assigned to 3 groups: SS, TS, and combined SS+TS interventions, each delivered as four 20-minute sessions. …”
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Norepinephrine titration in patients with sepsis-induced encephalopathy: cerebral pulsatility index compared to mean arterial pressure guided protocol: randomized controlled trial by Mai Salah Salem, Motaz Amr Abosabaa, Mohamed Samir Abd El Ghafar, Hala Mohey EI-Deen Mohamed EI-Gendy, Salah El-din Ibrahim Alsherif

“…Methods In this prospective, single-center randomized controlled study, 112 patients with SIE were randomly assigned. …”
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Assessing the application of adapted theory of planned behaviour in predicting postpartum family planning intentions in a pragmatic randomized control trial in Western Kenya. by Morris Senghor Shisanya, Mary Kipmerewo, Everlyne Morema, Collins Ouma

“…<h4>Methods</h4>This randomized control trial included pregnant women aged 15 to 49 attending Antenatal Care (ANC) clinics, randomly assigned to the "Nurses' arm," "Community arm," or "Control arm." …”
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Prospective Randomized Multicenter Comparison of the Clinical Outcomes of V4c and V5 Implantable Collamer Lenses: A Contralateral Eye Study by Takashi Kojima, Yoshihiro Kitazawa, Tomoaki Nakamura, Masahide Takahashi, Kazutaka Kamiya, Kazuo Ichikawa, Akihito Igarashi, Kimiya Shimizu

“…Design. Prospective randomized multicenter single-masked comparative study. …”
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Efficacy and safety of post-discharge oral nutritional supplements for patients with gastric cancer undergoing gastrectomy: a meta-analysis of randomized controlled trials by Qiuman Liang, Siyi Wang, Beibei Wang, Yanyan Hong

“…ObjectivesTo report the first and largest systematic review and meta-analysis of randomized controlled trials (RCT) to evaluated the efficacy and safety of post-discharge oral nutritional supplements (ONS) for patients with gastric cancer undergoing gastrectomy.DesignSystematic review and meta-analysis.Eligibility criteria for selecting studiesRCT which evaluated the efficacy and/or safety of post-discharge ONS for patients with gastric cancer undergoing gastrectomy.Data sourcesWe conducted a systematic literature retrieval via PubMed, Embase, Web of Science, and Cochrane until April, 2023 for relevant RCTs.Data analysisOutcomes of meta-analysis included absolute change of body weight, % change of body weight, absolute change of body composition, absolute change of laboratory parameters and adverse events. …”
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The effect of educational intervention based on the mobile application on women’s knowledge, attitude, and practice on microplastics and health: study protocol for a randomized controlled trial by Zahra Seifi, Fatemeh Zarei, Fazlollah Ahmadi

“…Methods This randomized controlled trial includes three phases. In the first phase, a questionnaire assessing women’s knowledge, attitudes, and practices (KAP) regarding microplastics will be developed and validated. …”
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TangBi Formula for Painful Diabetic Distal Symmetric Polyneuropathy: A Multicenter, Randomized, Double‐Blind, Placebo‐Controlled and Parallel‐Group Trial by Xuefei Zhao, Xuedong An, Yashan Cui, Liu Dong, Zhaohui Fang, Zhonghua Zheng, Xinhe Zuo, Huailin Gao, Tianshu Gao, Qing Ni, Fengmei Lian, Xiaolin Tong

“…Methods This multicenter, placebo‐controlled, double‐blind, randomized controlled clinical trial recruited patients from 6 clinical centers in mainland China. …”
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Comparison of Nasopharyngeal Airway with Endoscopic Respiratory Mask for Hypoxemia in Painless Gastrointestinal Endoscopy in Obese Outpatients: Study Protocol for a Randomized Controlled Trial by Xiang D, Deng L, Zhou R, Zhang X, Tian L, Jiang W, Zhou Y, Chen W, Peng Y

“…This study aims to investigate the effects of the nasopharyngeal airway in mitigating hypoxemia via alleviating upper airway obstruction in obese outpatients during painless gastrointestinal endoscopy procedure.Methods: This is a prospective single-center randomized controlled study. After signing the written informed consent, eligible outpatients scheduled for painless gastrointestinal endoscopy will be randomly allocated into the nasopharyngeal airway group (group N) and control group (group C), with 88 patients in each group. …”
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Faster Onset of Bronchodilation with Formoterol than with Salmeterol in Patients with Stable, Moderate-Severe Copd: Results of a Randomized, Double-Blind Clinical Study by John Kottakis, Giovanni Della Cioppa, Jacques Creemers, Louis Greefhorst, Violette Leclerc, Riccardo Pistelli, Tim Overend, Denise Till, Günter Rapatz, Vincent LeGros, Demosthenes Bouros, Nikolaos Siafakas

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Long‑term outcomes of adjustable gastric banding: a 15‑year prospective randomized trial comparing 2 band types in 103 patients by Žygimantas Juodeikis, Gintautas Brimas

“…Introduction: As the use of gastric bands diminishes in bariatric and metabolic surgery, we present the results of a 15-year randomized controlled trial comparing 2 distinct adjustable gastric bands. …”
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Probiotics supplementation for management of type II diabetes risk factors in adults with polycystic ovarian syndrome: a meta-analysis of randomized clinical trial by Chengcheng Zhang, Yingyue Sheng, Jinchi Jiang, Yuzheng Xue, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Jian Jin, Qixiao Zhai

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Comparison of Therapeutic Effects of Different Rehabilitation Methods on Patients Undergoing Total Knee Arthroplasty: A Network Meta‐Analysis of Randomized Controlled Trials by Zhaokai Jin, Yi Tang, Hua Huang, Lei Chen, Zhongyi Zhang, Tianyou Ma, Zhengming Wang, Hai Su, Haojing Zhou, Shuaijie Lv, Peijian Tong

“…Methods A comprehensive search of five databases and two clinical trial registration platforms was conducted from inception through March 31, 2024, and conducted to identify eligible randomized controlled trials (RCTs). We extracted the required data according to the Cochrane Handbook for Systematic Reviews of Interventions. …”
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Benzodiazepine agonist treatment for patients with benzodiazepine dependence undergoing opioid agonist treatment: a study protocol for the randomized controlled trial BMX-BAR by Fatemeh Chalabianloo, Lars Thore Fadnes, Jörg Assmus, Jon Mordal, Kristin K. Solli, Kjetil S. Dale, Christina D. Andersen, Silvia Zavenova, Beathe H. Rønning, Andreas W. Blomkvist, Martin Ryssdal, Wasifa S. J. Butt, Anne Marciuch, Anne G. Ørmen, Christian Ohldieck, Else-Marie Løberg, Kjell Arne Johansson, for the BMX-BAR and NORCATS study group

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Effectiveness of a Web-Based Medication Education Course on Pregnant Women’s Medication Information Literacy and Decision Self-Efficacy: Randomized Controlled Trial by Suya Li, Hui-Jun Chen, Jie Zhou, Yi-Bei Zhouchen, Rong Wang, Jinyi Guo, Sharon R Redding, Yan-Qiong Ouyang

“…The CONSORT-EHEALTH (V 1.6.1) checklist was used to guide the reporting of this randomized controlled trial. ResultsA total of 91 pregnant women (48 in the IG and 43 in the CG) completed the questionnaires at the 3 time points. …”
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Effects of Ciprofol and Propofol General Anesthesia on Postoperative Recovery Quality in Patients Undergoing Ureteroscopy: A Randomized, Controlled, Double-Blind Clinical Trial by Shi S, Wu J, Wu Y, Han X, Dai H, Chen X, Sun Z, Wang F

“…Shuqi Shi,1,2,&ast; Jimin Wu,1,&ast; Yini Wu,1 Xin Han,1 Hong Dai,1 Xuedong Chen,3 Zhangnan Sun,4 Faxing Wang1,2 1Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 2Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Urology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, Lishui, People’s Republic of China; 4Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Faxing Wang, Department of Anesthesiology, Lishui People’s Hospital, Wenzhou Medical University Lishui Hospital, The First Affiliated Hospital of Lishui University, No. 15, Dazhong Street, Lishui, Zhejiang Province, 323000, People’s Republic of China, Email wfx2023@wmu.edu.cn Zhangnan Sun, Department of Anesthesiology, The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, 050000, People’s Republic of China, Email 28703077@hebmu.edu.cnObjective: This study compares postoperative recovery quality between Ciprofol and Propofol, providing a reference for the clinical application of anesthetics.Methods: We randomized 112 patients undergoing ureteroscopic surgery into two groups: the Ciprofol group (Group C), with an induction dose of 0.4 mg/kg and a maintenance dose of 0.8– 1.5 mg/(kg·h), and the Propofol group (Group P), with an induction dose of 2 mg/kg and a maintenance dose of 4– 10 mg/(kg·h). …”
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