Removal of Nickel-63 Ions from Aqueous Solutions by Chitosan Flakes by M. Zamin, T. Shaheen, M. Ahmed

“…Radiotracer batch equilibrium experiments were undertaken to check the uptake of nickel-63 from aqueous solutions by a natural polymer, i.e. chitosan obtained from fishery wastes (shrimp, crab and prawn shells). …”
Get full text

Ectopic Lingual Thyroid by Khaled Khamassi, Habib Jaafoura, Fahmi Masmoudi, Rim Lahiani, Lobna Bougacha, Mamia Ben Salah

“…Thyroid scintigraphy showed intense and elective uptake of radiotracer at the base of the tongue. Hormonal tests revealed hypothyroidism. …”
Get full text

Thyroid Hemiagenesis Associated with Hyperthyroidism by Gunay Gurleyik, Emin Gurleyik

“…Nuclear scan, confirming absence of the left lobe, showed increasing diffuse uptake of radiotracer in the right one. The diagnosis was Graves’ disease in this patient. …”
Get full text

Cyclotron Production of High–Specific Activity Co and In Vivo Evaluation of the Stability of Co Metal-Chelate-Peptide Complexes by Tara Mastren, Bernadette V. Marquez, Deborah E. Sultan, Elizabeth Bollinger, Paul Eisenbeis, Tom Voller, Suzanne E. Lapi

“…These results support the use of 55 Co as a promising new radiotracer for PET imaging of cancer and other diseases.…”
Get full text

Insight into the Molecular Imaging of Alzheimer’s Disease by Abishek Arora, Neeta Bhagat

“…Multimodal neuroimaging techniques have indicated changes in brain structure and metabolic activity, and an array of neurochemical variations that are associated with neurodegenerative diseases. Radiotracer-based PET and SPECT potentially provide sensitive, accurate methods for the early detection of disease. …”
Get full text

Kinetic Analysis of [C]Vorozole Binding in the Human Brain with Positron Emission Tomography by Jean Logan, Sung Won Kim, Deborah Pareto, Frank Telang, Gene-Jack Wang, Joanna S. Fowler, Anat Biegon

“…Using positron emission tomography, we investigated the kinetics of [ 11 C]vorozole ([ 11 C]VOR), a radiotracer for the enzyme aromatase that catalyzes the last step in estrogen biosynthesis. …”
Get full text

First in Vivo SPECT Imaging of Mouse Femorotibial Cartilage Using Tc-NTP 15-5 by Elisabeth Miot-Noirault, Aurélien Vidal, Philippe Auzeloux, Jean-Claude Madelmont, Jean Maublant, Nicole Moins

“…This study aimed to report the first single-photon emission computed tomographic (SPECT) imaging of articular cartilage in mice using 99m Tc-NTP 15-5 radiotracer. Mice intravenously injected with 99m Tc-NTP 15-5 were submitted to (1) dynamic planar imaging, (2) static planar imaging, (3) 1 mm pinhole SPECT acquisition, and (4) dissection. …”
Get full text

Micro-PET Imaging of αβ-Integrin Expression with F-Labeled Dimeric RGD Peptide by Xiaoyuan Chen, Michel Tohme, Ryan Park, Yingping Hou, James R. Bading, Peter S. Conti

“…In particular, α v β 3 integrin, which is specifically expressed on proliferating endothelial cells and tumor cells, is a logical target for development of a radiotracer method to assess angiogenesis and anti-angiogenic therapy. …”
Get full text

The Values and Limitations of FDG-PET/CT for Diagnosis of Hibernoma by Jong Hoon Park, Koichi Ogura, Tomohiro Fujiwara, Akihito Nagano, Kunihiko Numoto, Takashi Terauchi, Akihiko Yoshida, Akira Kawai

“…Although the features of hibernoma demonstrated by MRI resemble those of liposarcoma, recent FDG-PET/CT studies have documented higher radiotracer uptake than liposarcoma, suggesting that FDG/PET/CT is useful for differentiating hibernoma from liposarcoma. …”
Get full text

Comparison of and as Reporter Genes for Noninvasive Imaging of Bone Mesenchymal Stem Cells Transplanted into Infarcted Rat Myocardium by Shuo Hu, Wei Cao, Xiaoli Lan, Yong He, Juntao Lang, Congjiao Li, Jia Hu, Rei An, Zairong Gao, Yongxue Zhang

“…The transfected rBMSCs were transplanted into infarcted rat myocardium followed by a single-photon emission computed tomography (SPECT) study with 99m Tc-pertechnetate as the radiotracer and by autoradiography. The isolated rBMSCs were CD29, CD44, and CD90 positive and CD34, CD45, and CD11b negative. …”
Get full text

Treatment with Octreotide in Patients with Well-Differentiated Neuroendocrine Tumors of the Ileum: Prognostic Stratification with Ga-68-DOTA-TATE Positron Emission Tomography by Walter Koch, Christoph J. Auernhammer, Julia Geisler, Christine Spitzweg, Clemens C. Cyran, Harun Ilhan, Peter Bartenstein, Alexander R. Haug

“…Patients with high radiotracer uptake had significantly higher PFS with a 2.9-fold higher chance for stable disease after 45 weeks; however, the prognostic performance of SUV max on an individual basis was poor, with a sensitivity of 75% and a specificity of 64%. …”
Get full text

Cabozantinib Resolves Bone Scans in Tumor-Naïve Mice Harboring Skeletal Injuries by Michael G. Doran, Daniel E. Spratt, John Wongvipat, David Ulmert, Brett S. Carver, Charles L. Sawyers, Michael J. Evans

“…A consistent reduction in the accumulation of either radiotracer at the site of bone remodeling was observed in animals treated with cabozantinib. …”
Get full text

Imaging Expression of Cytosine Deaminase-Herpes Virus Thymidine Kinase Fusion Gene (CD/TK) Expression with [I]FIAU and PET by Trevor Hackman, Michail Doubrovin, Julius Balatoni, Tatiana Beresten, Vladimir Ponomarev, Bradly Beattie, Ronald Finn, William Bornmann, Ronald Blasberg, Juri Gelovani Tjuvajev

“…The activity of HSV1-TK and CD subunits of the CD/TK gene product was assessed in different single cell-derived clones of W256CD/TK cells using the FIAU radiotracer accumulation assay in cells and a CD enzyme assay in cell homogenates, respectively. …”
Get full text

Development of a New Reporter Gene System-dsRed/Xanthine Phosphoribosyltransferase-Xanthine for Molecular Imaging of Processes Behind the Intact Blood-Brain Barrier by Mikhail Doubrovin, Vladimir Ponomarev, Inna Serganova, Suren Soghomonian, Tadashi Myagawa, Tatiana Beresten, Lyudmila Ageyeva, Michel Sadelain, Jason Koutcher, Ronald G Blasberg, Juri G. Gelovani Tjuvajev

“…In the in vivo experiment, the concentration of [* C]-xanthine in the normal brain varied from 0.20 to 0.16 + 0.05% dose/g under 0.87 + 0.24% dose/g plasma radiotracer concentration. The accumulation in vivo in the transfected flank tumor was to 2.4 ± 0.3% dose/g, compared to 0.78 ± 0.02% dose/g and 0.64 ± 0.05% dose/g in the control flank tumors and intact muscle, respectively. [ 14 C]-Xanthine appeared to be capable of specific accumulation in the transfected infiltrative brain tumor (RG2-dsRed/XPRT), which corresponded to the 585 nm fluorescent signal obtained from the adjacent cryosections. …”
Get full text

In Vitro and In Vivo Characterization of a Dual-Function Green Fluorescent Protein–HSV1-Thymidine Kinase Reporter Gene Driven by the Human Elongation Factor 1α Promoter by Gary D. Luker, Kathryn E. Luker, Vijay Sharma, Christina M. Pica, Julie L. Dahlheimer, Joe A. Ocheskey, Timothy J. Fahrner, Jeffrey Milbrandt, David Piwnica-Worms

“…These data extend previous reports by showing that a human promoter can be detected in vitro and in vivo with a dual-function reporter exploiting optical and radiotracer techniques.…”
Get full text

Parathyroid Carcinoma in the Setting of Tertiary Hyperparathyroidism: Case Report and Review of the Literature by Federico Cappellacci, Fabio Medas, Gian Luigi Canu, Maria Letizia Lai, Giovanni Conzo, Enrico Erdas, Pietro Giorgio Calò

“…Neck ultrasound (US) showed a solid hypodense mass, probably the right inferior parathyroid gland, with an estimated size of 25 × 15 × 13 mm; the 99mTc-sestamibi SPECT/CT scan revealed a large radiotracer activity area in the right cervical region, compatible with a hyperfunctioning right inferior parathyroid gland. …”
Get full text

Technical Considerations of Phosphorous-32 Bremsstrahlung SPECT Imaging after Radioembolization of Hepatic Tumors: A Clinical Assessment with a Review of Imaging Parameters by Elahe Pirayesh, Mahasti Amoui, Shahram Akhlaghpoor, Shahnaz Tolooee, Maryam Khorrami, Hossain PoorBeigi, Shahab Sheibani, Majid Assadi

“…Bremsstrahlung (BS) imaging during radioembolization (RE) confirms the deposition of radiotracer in hepatic/extrahepatic tumors. The aim of this study is to demonstrate 32P images and to optimize the imaging parameters. …”
Get full text

A Monte Carlo simulation study of the impact of increasing the axial field of view on PET scanner sensitivity with various scintillating crystals by El Ouaridi Abdallah, Ait Elcadi Zakaria, Mkimel Mounir, Bougteb Mustapha, El Baydaoui Redouane

“…This study addresses sensitivity performance, a pivotal parameter of Positron Emission Tomography (PET) imaging, which measures the system’s ability to detect and precisely measure radiotracer signals. It primarily depends on the scintillation material and the system’s axial field of view (AFOV). …”
Get full text

Is preoperative imaging of sentinel lymph node in breast cancer necessary? A retrospective case control study by Michael J. Reinhardt, Björn Ohmstede, Luz Angela Torres-de la Roche, Rudy Leon De Wilde

“…Due to the additional SLN imaging in group 2, the time between radiotracer injection and start of surgery was significantly prolonged (p < 0.001). …”
Get full text

Preliminary Assessment of Reference Region Quantification and Reduced Scanning Times for [18F]SynVesT-1 PET in Parkinson’s Disease by Kelly Smart, Carme Uribe, Kimberly L. Desmond, Sarah L. Martin, Neil Vasdev, Antonio P. Strafella

“…There were no significant group differences in CS volume, radiotracer uptake, or efflux (ps>0.47). Each fitting method produced BPND estimates in close agreement with those derived from the 1TCM (subject R2s>0.98, bias<10%), with no difference in bias between the control and PD groups. …”
Get full text