The role of smell in medical and psychological disorders: An interdisciplinary approach by Giuseppe Riva

“…Furthermore, the psychophysical evaluation of olfactory impairments associated with some treatments, such as radiotherapy and chemotherapy, and with several types of rhinitis could help address patients’ complaints, and increase the patient’s quality of life [10, 11]. …”

Neoadjuvant chemoradiotherapy up-regulates PD-L1 in radioresistant colorectal cancer by Sung Uk Bae, Hye Won Lee, Jee Young Park, Incheol Seo, Jae-Min Cho, Jin Young Kim, Ju Yup Lee, Yoo Jin Lee, Seong Kyu Baek, Nam Kyu Kim, Sang Jun Byun, Shin Kim

“…Background: Combining radiotherapy (RT) with immune checkpoint inhibitors (ICIs) is a promising strategy that can enhance the therapeutic efficacy of ICIs. …”
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Utilization of patient-reported outcomes to assess adherence to relugolix when combined with stereotactic body radiation therapy for intermediate to high-risk prostate cancer by Kelly Gaudian, Min Jung Koh, Min Ji Koh, Ryan R. Collins, Shaine Eden, Zoya Zwart, Malika Danner, Alan Zwart, Mark Fallick, Deepak Kumar, Paul Leger, Nancy A. Dawson, Simeng Suy, Sean P. Collins

“…IntroductionInjectable GnRH receptor agonists have been shown to improve cancer control when combined with radiotherapy (RT). Relugolix is an oral GnRH receptor antagonist that achieves rapid testosterone suppression. …”
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Construction of feature selection and efficacy prediction model for transformation therapy of locally advanced pancreatic cancer based on CT, 18F-FDG PET/CT, DNA mutation, and CA19... by Liang Qi, Xiang Li, Jiayao Ni, Yali Du, Qing Gu, Baorui Liu, Jian He, Juan Du

“…Abstract Background Immunotherapy and radiotherapy play crucial roles in the transformation therapy of locally advanced pancreatic cancer; however, the exploration of effective predictive biomarkers has been unsatisfactory. …”
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Brucea javanica oil inhibited the proliferation, migration, and invasion of oral squamous carcinoma by regulated the MTFR2 pathway by Yihan Lai, Yihan Lai, Mingkang Li, Mingkang Li, Juan Zhan, Juan Zhan, Lin Jiang, Lin Jiang, Yuan Wu, Zhiyi Fang, Jianhan Zhou, Jianhan Zhou, Yujie Ma, Yisen Shao, Yisen Shao, Wei Wang, Wei Wang

“…The development of new chemotherapy agents and new drug combinations may improve patient survival and quality of life, but both surgery and radiotherapy have significant functional side effects and drug resistance, ultimately resulting in a 5-year survival rate of no more than 60% for OSCC patients. …”
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Investigating POU3F4 in cancer: Expression patterns, prognostic implications, and functional roles in tumor immunity by Weiwei Chen, Yaya Ji, Rui Wang, Ruijie Ji, Yujian Lin, Yuhang Wu, Lehan Liu, Tianle Sha, Wen Li, Lei Zhang, Longfei Yang, Xinhua Zhang, Jianxiang Song

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Maintenance of patient-reported health-related quality of life post neoadjuvant relugolix prior to the initiation of prostate radiation therapy by Min Jung Koh, Min Ji Koh, Jessica Y. Hsueh, Lindsey Gallagher, Malika Danner, Alan Zwart, Marilyn Ayoob, Deepak Kumar, Michael Carrasquilla, Paul Leger, Nancy A. Dawson, Simeng Suy, Sean P. Collins

“…IntroductionStudies have demonstrated that injectable GnRH receptor agonists further suppress cancer progression when paired with radiotherapy (RT) in patients with intermediate- to high-risk prostate adenocarcinoma. …”
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An Overview of Patient-reported Outcomes for Men with Prostate Cancer: Results from the PIONEER Consortium by Sebastiaan Remmers, Katharina Beyer, Tariq A. Lalmahomed, Peter Prinsen, Nicole J.E. Horevoorts, Nora Tabea Sibert, Christoph Kowalski, Francesco Barletta, Oliver Brunckhorst, Giorgio Gandaglia, Jochem R.N. van der Voort van Zyp, Emma J. Smith, Andre Deschamps, Laurence Collette, Philip Cornford, Susan Evans-Axelsson, James N’Dow, Mieke Van Hemelrijck, Monique J. Roobol, Lionne D.F. Venderbos

“…Using prospectively collected data from the Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) consortium, we aimed to describe the functional status and QoL in men with prostate cancer (PCa) treated with active surveillance (AS), radical prostatectomy (RP), and radiotherapy (RT), and to demonstrate the applicability of PROM data on a large scale and at a European level. …”
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Physical Performance and Activity in Older Prostate Cancer Survivors in Comparison with Population-based Matched Controls by Reidun Sletten, Marit Slaaen, Line Merethe Oldervoll, Håvard Kjesbu Skjellegrind, Jūratė Šaltytė Benth, Lennart Åstrøm, Øyvind Kirkevold, Sverre Bergh, Bjørn Henning Grønberg, Siri Rostoft, Asta Bye, Paul Jarle Mork, Ola Berger Christiansen

“…Methods: A single-centre, cross-sectional study including 109 men aged ≥70 yr receiving robotic-assisted radical prostatectomy (61.5%) or external beam radiotherapy (38.5%) between 2014 and 2018 was conducted. …”
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Temporal trends in guideline-recommended medical therapy after an acute heart failure decompensation event: an observational analysis from Generator Heart Failure DataMart by Antonio Gasbarrini, Giuseppe Patti, Filippo Crea, Giovanni Scambia, Domenico D'Amario, Vincenzo Valentini, Gianluigi Savarese, Alfredo Cesario, Jacopo Lenkowicz, Stefano Patarnello, Renzo Laborante, Agni Delvinioti, Andrada Mihaela Tudor, Chiara Iacomini, Antonio Iaconelli, Donato Antonio Paglianiti, Mattia Galli, Daniele Rodolico, Attilio Restivo, Giuseppe Ciliberti, Gaetano Rizzo, Emiliano Bianchini, Matteo Busti, Luca Sensini

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A co-registration method to validate in vivo optical coherence tomography in the breast surgical cavity by Rowan W. Sanderson, Renate Zilkens, Peijun Gong, Imogen Boman, Ken Y. Foo, Skandha Shanthakumar, James Stephenson, Wei Ling Ooi, José Cid Fernandez, Synn Lynn Chin, Lee Jackson, Mireille Hardie, Benjamin F. Dessauvagie, Anmol Rijhumal, Saud Hamza, Christobel M. Saunders, Brendan F. Kennedy

“…Breast-conserving surgery accompanied by adjuvant radiotherapy is the standard of care for patients with early-stage breast cancer. …”
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Hydrogen‐Generating Magnesium Alloy Seed Strand Sensitizes Solid Tumors to Iodine‐125 Brachytherapy by Pan Hu, Letao Lin, Guanyu Chen, Dengyao Liu, Huanqing Guo, Meigui Xiao, Zhihui Zhong, Guang Yang, Bingchen Xu, Dongcun Huang, Sheng Peng, Yong Li, Yanling Zhang, Tao Huang, Fujun Zhang

“…However, its role in radiotherapy sensitization has rarely been reported. …”
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Current situation of central nervous system tumour survivors in a spanish hospital by Ivonne Marcela Rincón-Mantilla, Blanca Herrero, Elena Herranz Valero, Fernando Robles-Bermejo, Alba Herrera-Olivares, Felisa Vázquez-Gómez, Álvaro Lassaletta

“…The aim of our study was to evaluate late morbidity, health-related quality of life (HRQoL), self-esteem, functional status, adaptive behaviour, physical activity and social outcomes such as education, employment, relationship status and possession of a driver’s license, in addition to the role of LT effects of radiotherapy (RTx) on these outcomes. Methods: The study included 111 CNS tumour survivors with a minimum of 10 years of follow-up. …”
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Several factors that predict the outcome of large B‐cell lymphoma patients who relapse/progress after chimeric antigen receptor (CAR) T‐cell therapy can be identified before cell a... by Alice Sýkorová, František Folber, Kamila Polgárová, Heidi Móciková, Juraj Ďuraš, Kateřina Steinerová, Aleš Obr, Adriana Heindorfer, Miriam Ladická, Ľubica Lukáčová, Erika Čellárová, Ivana Plameňová, David Belada, Andrea Janíková, Marek Trněný, Tereza Jančárková, Vít Procházka, Andrej Vranovský, Margaréta Králiková, Jan Vydra, Lukáš Smolej, Ľuboš Drgoňa, Martin Sedmina, Eva Čermáková, Robert Pytlík

“…Of these patients, 39 received radiotherapy or systemic therapy, with an ORR of 22% (CR 8%). …”
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Anti-LAG-3 antibody LBL-007 plus anti-PD-1 antibody toripalimab in advanced nasopharyngeal carcinoma and other solid tumors: an open-label, multicenter, phase Ib/II trial by Gang Chen, Dong-Chen Sun, Yi Ba, Ya-Xiong Zhang, Ting Zhou, Yuan-Yuan Zhao, Hong-Yun Zhao, Wen-Feng Fang, Yan Huang, Zhen Wang, Chao Deng, De-Sheng Hu, Wei Wang, Jin-Guan Lin, Gui-Ling Li, Su-Xia Luo, Zhi-Chao Fu, Hai-Sheng Zhu, Hui-Li Wang, Sheng-Li Cai, Xiao-Qiang Kang, Li Zhang, Yun-Peng Yang

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A Meta-analysis of Sanyrene in preventing radiation dermatitis of head and neck tumor (赛肤润预防头颈部肿瘤放射性皮炎的Meta分析) by ZHENG Ya (郑雅), ZENG Guqing (曾谷清), PENG Lingying (彭玲英), NI Xiaoyan (倪晓燕), WANG Aoyi (王傲一), PAN Rongjia (潘荣佳), NIAN Fang (年芳)

“…Objective To systematically evaluate the efficacy of Sanyrene in preventing radiation dermatitis after radiotherapy for head and neck tumors. Methods The data of PubMed, Cochrane Library, Embase, Web of Science, CBM database, Viper database, Wanfang database and CNKI database were searched, and randomized controlled studies on the use of Sanyrene to prevent radiation dermatitis were collected. …”
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Association of quality of life in older patients with breast cancer: a cross-sectional study from China by Xi Chen, Qing Li, Xiang Wang, Lei Ji, Jintao Zhang, Qiao Li, Min Xiao, Shanshan Chen, Pin Zhang, Jiani Wang, Heng Cao, Xiaoyan Qian, Meng Xiu, Zhuoran Li, Yiqun Li, Xiaojuan Zheng

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Translation of PET radiotracers for cancer imaging: recommendations from the National Cancer Imaging Translational Accelerator (NCITA) consensus meeting by Martina A. McAteer, Daniel R. McGowan, Gary J. R. Cook, Hing Y. Leung, Tony Ng, James P. B. O’Connor, Luigi Aloj, Anna Barnes, Phil J. Blower, Kevin M. Brindle, John Braun, Craig Buckley, Daniel Darian, Paul Evans, Vicky Goh, David Grainger, Carol Green, Matt G. Hall, Thomas A. Harding, Catherine D. G. Hines, Simon J. Hollingsworth, Penny L. Hubbard Cristinacce, Rowland O. Illing, Martin Lee, Baptiste Leurent, Sue Mallett, Radhouene Neji, Natalia Norori, Nora Pashayan, Neel Patel, Kieran Prior, Thomas Reiner, Adam Retter, Alasdair Taylor, Jasper van der Aart, Joseph Woollcott, Wai-Lup Wong, Jan van der Meulen, Shonit Punwani, Geoff S. Higgins

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Detection of alteration in carotid artery volumetry using standard-of-care computed tomography surveillance scans following unilateral radiation therapy for early-stage tonsillar s... by Efstratios Koutroumpakis, Mohamed A. Naser, Abdallah Sherif Radwan Mohamed, Salman A. Eraj, Andrea Jarre, Jay C. Shiao, Mona Kamal, Subha Perni, Jack P. Phan, William H. Morrison, Steven J. Frank, G.Brandon Gunn, Adam S. Garden, Anita Deswal, Jun-ichi Abe, David I. Rosenthal, Elie Mouhayar, Clifton D. Fuller

“…Aim: This study leveraged standard-of-care CT scans of patients receiving unilateral radiotherapy (RT) for early tonsillar cancer to detect volumetric changes in the carotid arteries, and determine whether there is a dose–response relationship. …”
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Comprehensive analysis of endoscopic ultrasound (EUS) in mediastinal lesions: patient characteristics, diagnostic outcomes, safety, and efficacy: a multi-country study by Hussein Okasha, Eyad Gadour, Ghias Un Nabi Tayyab, Andrada Seicean, Elbacha Hicham, Emad Emad, Turki Alamri, Nadeem Tehami, Heero Ismael Faraj, Ahmed Alzamzamy, Hiwa Hussein, Mohammed Tag-Adeen, Mohamed Elbasiony, Abed Al-Lehibi, Shereen Saleh, Zaher Houmani, Mohamed Abdelghani, Khaled Ragab, Zahi Ismaili, Othmane Drir, Elsayed Ghoneem, Omar Abdallah, Souad Rebiai, Nonthalee Pausawasdi, Fedoua Rouibaa, Mohamed Borahma, Hassan Atalla, Mahmoud Farouk, Ahmed Altonbary

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