Impact of Physical Activity on Cancer-Specific and Overall Survival of Patients with Colorectal Cancer by Gaetan Des Guetz, Bernard Uzzan, Thierry Bouillet, Patrick Nicolas, Kader Chouahnia, Laurent Zelek, Jean-François Morere

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PropAngio study protocol: a neoadjuvant trial on the efficacy of propranolol monotherapy in cutaneous angiosarcoma—a proof of principle study by Neeltje Steeghs, Jos H Beijnen, Kimberley M Heinhuis, Nikki S IJzerman, Anne Miek Koenen, Winette T A van der Graaf, Rick L Haas, Alwin D R Huitema, Winan J van Houdt

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Unraveling the Anti-Cancer Mechanisms of Antibiotics: Current Insights, Controversies, and Future Perspectives by Nikolaos Nektarios Karamanolis, Dimitris Kounatidis, Natalia G. Vallianou, Krystalia Dimitriou, Eleni Tsaroucha, Georgios Tsioulos, Ioanna A. Anastasiou, Evangelos Mavrothalassitis, Irene Karampela, Maria Dalamaga

“…Furthermore, antibiotics have demonstrated the potential to enhance the efficacy of conventional modalities like chemotherapy and radiotherapy, while alleviating treatment-induced toxicities. …”
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The association between body composition and overall survival in patients with advanced non-small cell lung cancer by Liang Fu, Haiming Ding, Liupei Mo, Xiaoyu Pan, Lijuan Feng, Shenglian Wen, Qiaoqing Lan, Liling Long

“…After adjusting for clinical variables such as gender, smoking status, clinical staging, degree of differentiation, and radiotherapy history, the multivariable Cox regression analysis showed that an increase in SFI significantly improves the overall survival rate of patients (Hazard Ratio [HR] = 1.410, 95% Confidence Interval [CI]: 1.042–1.908, P = 0.026). …”
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Enhancing immunotherapy efficacy with synergistic low-dose radiation in metastatic melanoma: current insights and prospects by Zahid Rafiq, Mingyo Kang, Hampartsoum B. Barsoumian, Gohar S. Manzar, Yun Hu, Carola Leuschner, Ailing Huang, Fatemeh Masrorpour, Weiqin Lu, Nahum Puebla-Osorio, James W. Welsh

“…The convergence of LDRT with other disciplines holds immense potential for developing novel radiotherapy-combined modalities, paving the way for more effective and personalized treatment strategies in melanoma and beyond. …”
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Case report of the first use of a hydrogel rectal spacer for prostate cancer reirradiation via LDR brachytherapy: applications and technical notes by Amina Lazrek, Sebastiano Finocchi Ghersi, Adeline Petre, Sarah Houabes, Anne-Agathe Serre, Frederic Gassa, Magali Sandt, Cecile Laude, Camille Roukoz, Salvatore Cozzi

“…This article examines the critical role of a biodegradable hydrogel spacer, which creates a temporary interspace between the prostate and the rectum, thus reducing radiation exposure to healthy tissues.Case descriptionWe present a case of a man with a history of intermediate-risk prostate adenocarcinoma initially treated with external beam radiotherapy in 2015. Despite initial remission, the patient experienced a rise in prostate-specific antigen (PSA) levels indicative of local recurrence in 2022. …”
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99mTc(CO)3-Labeled 1-(3-Nitropyridin-2-yl) Piperazine as Potential Radioligand for 5-HT7 Receptors by Sajjad Molavipordanjani

“…The standard treatment for GBM involves a combination of surgery, radiotherapy and chemotherapy. However, GBM tumors are highly diffuse and exhibit a significant risk of recurrence. …”
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Sulforaphane Wrapped in Self-Assembled Nanomicelle Enhances the Effect of Sonodynamic Therapy on Glioma by Yihong Li, Xuejie Yang, Zhen Wei, Heng Niu, Liyang Wu, Caijing Chen, Huina Liu, Ting Cai, Huadong Fan

“…<b>Background/Objectives:</b> The two obstacles for treating glioma are the skull and the blood brain–barrier (BBB), the first of which forms a physical shield that increases the difficulties of traditional surgery or radiotherapy, while the latter prevents antitumor drugs reaching tumor sites. …”
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An ultrasound-driven PLGA/Zn-KNN hybrid piezoelectric scaffold with direct and immunoregulatory antibacterial activity for bone infection by Yuhao Zheng, Shu Wang, Wenhe Jin, Zhuoxuan Li, Guoju Yang, Xiaoxu Li, Ning Li, Yue Wang, Fan Sheng, Zhiming Song

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Low-Dose Irradiation Differentially Impacts Macrophage Phenotype in Dependence of Fibroblast-Like Synoviocytes and Radiation Dose by Lisa Deloch, Jana Fuchs, Michael Rückert, Rainer Fietkau, Benjamin Frey, Udo S. Gaipl

“…The latter innate immune cells show a high plasticity in their phenotype and are central in inflammatory processes. Low-dose radiotherapy (LD-RT) with particularly a single dose of 0.5 Gy has been demonstrated to have a positive impact on pain, inflammation, and bone in inflamed joints. …”
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Computed tomography–guided percutaneous biopsy in diagnosis of suspected metastatic renal cell carcinoma: which location is the most suitable? by Petr Hoffmann, Michal Balik, Martina Hoffmannova, Jindrich Kopecky, Pavel Ryska, Jana Draganovicova, Petr Dvorak

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Positive Expression of IGFBP2 as a Novel Prognostic Biomarker for Patients with Lower-Grade Gliomas by Yanguo Li, Jiawei Fan, Zhuo Shen, Jun Zhang, Xuemei Yin, Fang Han, Wenfei Li

“…For patients with LGG overexpressing IGFBP2, radiotherapy may be a preferable choice over chemotherapy.…”
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Primary tracheo‐bronchial adenoid cystic carcinoma: A surgical series with literature review by Kaouther Ben Amara, Imen Bouassida, Rahma Ayadi, Mariem Affes, Amina Abdelkbir, Mahdi Abdennadher, Salma Ben Othmen, Ayda Ayadi‐Kaddour, Hazem Zribi, Adel Marghli

“…Surgery followed by adjuvant radiotherapy was performed in two patients with incomplete surgical resection R1. …”
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The preoperative neutrophil‐to‐lymphocyte ratio is not a marker of prostate cancer characteristics but is an independent predictor of biochemical recurrence in patients receiving r... by Zhi Cao, Jin Ji, Chao Zhang, Fubo Wang, Huan Xu, Yongwei Yu, Yinghao Sun

“…When we analyzed the data of patients without postoperative adjuvant hormone therapy or radiotherapy, univariate and multivariate survival analysis indicated that a high NLR was a predictor of better BCR‐free survival (P < 0.05). …”
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Malignant Paraganglioma With Calvarial Metastases Presenting With Recurrent Catecholamine-Induced Cardiomyopathy by Beatrice A. Brumley, MD, Run Yu, MD, PhD, Shadfar Bahri, MD, Jane Rhyu, MD

“…Because of potential neurotoxicity, radiology advised against radiotherapy. Oncology advised monitoring. Seven months postoperatively, gallium-68 dodecane tetraacetic acid–octreotate positron emission tomography/computed tomography showed no recurrence at the surgical site, stable occipital lesion, and additional skeletal metastases. …”
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Successful Neurological Recovery with Multimodality Therapy without Surgery for Spinal Metastases from Advanced Gastric Cancer by Hideyuki Kinoshita, Hiroto Kamoda, Takeshi Ishii, Yoko Hagiwara, Toshinori Tsukanishi, Yusuke Amanuma, Rino Nankinzan, Sumihisa Orita, Kazuhide Inage, Naoya Hirosawa, Seiji Ohtori, Tsukasa Yonemoto

“…She was inoperable, owing to a large thrombus in the inferior vena cava; alternative multimodality treatments, including chemotherapy and radiotherapy, were administered. The paralysis and the bladder and rectal dysfunction improved considerably. …”
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EMA/CO Combination Chemotheraphy in Gestational Trophoblastic Neoplasia: Update of Our Results by Tolga Taşçı, Işın Üreyen, Günsu Kimyon, Alper Karalök, Sevgi Koç, M. Faruk Köse, Gökhan Tulunay, Taner Turan

“…Adjuvant surgery and radiotherapy were used in selected patients. Response and effects of the prognostic factors to the response rate were analyzed. …”
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Lymphopenia Is Associated with Gross Target Volumes and Fractions in Hepatocellular Carcinoma Patients Treated with External Beam Radiation Therapy and Also Indicates Worse Overall... by Hai-Ge Zhang, Ping Yang, Tao Jiang, Jian-Ying Zhang, Xue-Juan Jin, Yong Hu, Jing Sun, Shi-Suo Du, Zhao-Chong Zeng

“…Total lymphocyte counts were collected from 184 HCC patients treated by radiotherapy (RT) with complete follow-up. Associations between gross tumor volumes (GTVs) and radiation-associated parameters with lymphocyte nadir were evaluated by Pearson/Spearman correlation analysis and multiple linear regression. …”
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Long-Term Intracranial Progression-Free Survival in Lung Cancer Brain Metastases Extended Beyond 50 Months with Gubenxiaoyi Formula (GBXY): A Groundbreaking Case Study by Zhengzheng Yang, Haiming Li, Lei Chen, Shujiao Li, Dong Chen, Taicheng Lu, Tongjing Ding, Ruiyang Han, Peiyu Cheng, Xiaomin Wang

“…Case presentation Here, we present a case of a middle-aged female with lung cancer BM, whose condition was assessed as progressive post-standard treatment including two local surgeries (both involving resection of cerebellar space-occupying lesions), stereotactic radiotherapy, chemotherapy and EGFR-TKIs. Subsequently, she underwent treatment with the traditional Chinese herbal formula gubenxiaoyi (GBXY). …”
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ROS-regulated SUR1-TRPM4 drives persistent activation of NLRP3 inflammasome in microglia after whole-brain radiation by Yuan Chang, Yihua He, Di Wang, Kunxue Zhang, Yuzhen Zhang, Zhentong Li, Shuxin Zeng, Sheng Xiao, Suyue Pan, Kaibin Huang

“…Abstract Delayed radiation-induced brain injury (RIBI) characterized by progressive cognitive decline significantly impacts patient outcomes after radiotherapy. The activation of NLRP3 inflammasome within microglia after brain radiation is involved in the progression of RIBI by mediating inflammatory responses. …”
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