Effects of radiation and manganese oxide nanoparticles on human glioblastoma cell line U-87 MG glycolysis by N. B. Illarionova, D. V. Petrovski, I. A. Razumov, E. L. Zavyalov

“…Standard treatment of gliomas consists of surgical excision of the tumor with subsequent chemotherapy and radiotherapy. Tumor cells are characterized by rapid division with an increased uptake of glucose and its catabolism during glycolysis. …”
Get full text

Immunotherapy in the Treatment of Metastatic Melanoma: Current Knowledge and Future Directions by Massimo Ralli, Andrea Botticelli, Irene Claudia Visconti, Diletta Angeletti, Marco Fiore, Paolo Marchetti, Alessandro Lambiase, Marco de Vincentiis, Antonio Greco

“…Recent studies have shown a significantly higher success rate with combination of immunotherapy and chemotherapy, radiotherapy, or targeted molecular therapy. Immunotherapy is associated to a panel of dysimmune toxicities called immune-related adverse events that can affect one or more organs and may limit its use. …”
Get full text

Esophageal Gastrointestinal Stromal Tumor with Rare Intracranial Metastasis by José Carvalho, Margarida Teixeira, Francisco Teixeira Silva, Alexandra Esteves, Carlos Ribeiro, Diana Guerra

“…Imatinib was maintained, and whole brain radiotherapy was performed. After 6 months, she died. …”
Get full text

From Nonfunctioning Adrenocortical Cancer to Biochemically Silent Paraganglioma Associated with SDHB Mutation: An Uncommon Presentation of a Patient with a Retroperitoneal Mass by Izabella Freitas, Anna Albuquerque, Luiz de Marco, null Eduardo, José Renan Melo, Juliana Drummond, Beatriz Rocha

“…Systemic chemotherapy and abdominal radiotherapy were performed, in addition to multiple surgical resections, with no satisfactory response. …”
Get full text

Initial Treatment Modalities in Patients with Newly Diagnosed Primary Lung Cancer in Japan by Qingqing Hu, Kuan-Chih Huang, Ko Nakajo, Yongjing Zhang, Hong Qiu

“…The observed trends were a decrease in the percentage of newly diagnosed patients with distant metastases, a decline in chemotherapy use in patients with early-stage disease, and in advanced disease, a more than doubling in the use of targeted therapy, including checkpoint inhibitors, while radiotherapy and chemotherapy tended to decrease. The observed changes in treatment were driven mainly by the increased use of targeted therapies including checkpoint inhibitors and are aligned with current treatment guidelines in Japan. …”
Get full text

MEASUREMENT OF RADIATION EXPOSURE IN FACILITIES FOR RADIOLOGY DIAGNOSTIC AT THE COVID-19 EMERGENCY HOSPITAL IN WISMA ATLET JAKARTA by Muhammad Irsal, Firdha Adlia Syuhada, Yolanda Pangestu Ananda, Andre Galih Pratama Putra, Muhammad Rizky Syahputera, Syahputera Wibowo

Get full text

Absorbed Dose Measurements for Teletheraphy Prediction of Superficial Dose Using Halcyon Linear Accelerator by Raymond Njinga, Adeneye Samuel, Akinyode Ajimo, Christopher Olowookere

Get full text

Advances in preclinical and clinical studies of oncolytic virus combination therapy by Wenlong Du, Jintong Na, Liping Zhong, Liping Zhong, Pumin Zhang

“…This paper summarizes the tumor-killing mechanisms of oncolytic viruses, explores their integration with radiotherapy, chemotherapy, immune checkpoint inhibitors, CAR-T, and CAR-NK therapies, and provides an overview of related clinical trials. …”
Get full text

Development and validation of a prognostic nomogram model in primary cutaneous and subcutaneous soft tissue angiosarcoma by Jinqian Mao, Jin Hu, Yunfei Chen, Yiqing Li, Xiaoqin Run

“…All data were randomly allocated into a training set and a testing set to develop and validate the nomogram model.Results The findings showed that age, sex, grade, tumor size, multiple primary malignant tumors, stage, primary site surgery (PSS), radiotherapy (RT), and chemotherapy (CT) were correlated with prognosis (p < .05). …”
Get full text

Large Cell Neuroendocrine Carcinoma of the Bladder with Adenocarcinomatous Component by Rami Halabi, Maher Abdessater, Johnny Boustany, Anthony Kanbar, Halim Akl, Joey El Khoury, Charbel El Hachem, Raghid El Khoury

“…The patient was treated by recurrent tumor resections, chemotherapy, and radiotherapy. No improvement was noted despite close follow-up and adequate treatment. …”
Get full text

An Inflammatory Pseudotumor Arising from Pterygopalatine Fossa with Invasion to the Maxillary Sinus and Orbital Cavity by Hidenori Yokoi, Takuya Yazawa, Yuma Matsumoto, Tetsuya Ikeda, Masachika Fujiwara, Yasuo Ohkura, Naoyuki Kohno

“…The patient had a lymphoid-predominant lesion that responded to radiotherapy but corticosteroids were not effective. …”
Get full text

Disseminated Cerebrospinal Embryonal Tumor in the Adult by Alessandro Caporlingua, Daniele Armocida, Federico Caporlingua, Gennaro Lapadula, Grazia Maria Elefante, Manila Antonelli, Maurizio Salvati

“…Postoperative adjuvant therapy might entail both chemo- and radiotherapy; however a consensus on this matter is still lacking.…”
Get full text

Bioinformatics analysis of mitochondrial metabolism-related genes demonstrates their importance in renal cell carcinoma by Mohsen Ahmadi, Maryam Motallebinezhad, Pegah Mousavi, Amir Hossein Miladipour, Shamim Fooladgar, Soudeh Ghafouri-Fard, Seyed Amirhossein Fazeli

“…Abstract Purpose Clear cell renal cell carcinoma (ccRCC) is resistant to radiotherapy and chemotherapy. Thus, it is necessary to find new diagnostic markers and therapeutic targets to increase the overall outcomes of ccRCC. …”
Get full text

RETRACTED ARTICLE: Inhibition of PAD4 enhances radiosensitivity and inhibits aggressive phenotypes of nasopharyngeal carcinoma cells by Hao Chen, Min Luo, Xiangping Wang, Ting Liang, Chaoyuan Huang, Changjie Huang, Lining Wei

“…Peptidyl-arginine deiminase 4 (PAD4) is a vital mediator of histone citrullination and plays an essential role in regulating disease process. Radiotherapy is an essential method to treat NPC. In this research, we explored the effect of PAD4 on NPC radiosensitivity. …”
Get full text

The first case of esophageal mediastinal fistula after immunotherapy for non-small cell lung cancer: case report and literature review by Tianxiao Fu, Jiu Chen, Bing Xiong, Guolin Wu

“…Abstract Background Malignant esophageal mediastinal fistula is a severe complication that occurs in both the advanced stages of esophageal cancer and after radiotherapy for esophageal cancer. Esophageal mediastinal fistula is very susceptible to complications such as mediastinitis and mediastinal abscess, resulting in a significantly elevated mortality rate for patients. …”
Get full text

Non-neoplastic proliferative inflammatory aspect of mucoepidermoid carcinomas involving retromolar trigone: A relevant and ignored clinical aspect by Isabel Schausltz Pereira Faustino, Luan Cesar Silva, Joab Cabral Ramos, Ana Carolina Evangelista Colafemina, Mariana de Pauli Paglioni, Alan Roger Santos-Silva, Pablo Agustin Vargas, Marcio Ajudarte Lopes

“…Both patients were treated with surgery, and one patient received selective neck dissection and adjuvant radiotherapy. Although the clinical appearance of palate MEC is widely recognized, few reports illustrate the clinical aspect of MEC in the retromolar trigone and, therefore, the present report highlights two cases of MEC with a peculiar clinical presentation.…”
Get full text

Fluorescence molecular imaging-guided photodynamic therapy for early breast cancer in the prone position: Feasibility evaluation with Monte Carlo simulations by Yugo Minegishi, Yasutomo Nomura

“…As a promising alternative to recently developed magnetic resonance imaging-guided radiotherapy, we proposed fluorescence molecular imaging-guided photodynamic therapy (FMI-guided PDT), which requires no expensive equipment. …”
Get full text

Evaluation of heart rate and pulmonary uptake in dipyridamole myocardial perfusion imaging in patients with suspected coronary artery disease and their relationship with clinical r... by Siamak Derakhshan, Bahar Moassesghafari, Khaled Rhmani

Get full text

Fertility Preservation in Girls by Jennia Michaeli, Michael Weintraub, Eitan Gross, Yehuda Ginosar, Vardit Ravitsky, Einat Eizenman, Eduardo Mitrani, Meital Lebovich, Neri Laufer, Stephen Kennedy, Ariel Revel

“…Children that undergo treatment for cancer are at risk of suffering from subfertility or hormonal dysfunction due to the detrimental effects of radiotherapy and chemotherapeutic agents on the gonads. …”
Get full text

Sinonasal Melanoma: A Case Report and Literature Review by I. S. S. Alves, L. G. S. Berriel, R. T. Alves, M. B. Pinto, C. F. P. Oliveira, A. C. Cazzotto, W. V. Moura

“…The patient was then submitted to radiotherapy with concomitant cisplatin. Immunochemical analysis revealed positivity for vimentin, S100, and HMB-45 (human melanoma black 45), a result compatible with a diagnosis of malignant melanoma. …”
Get full text