Retrospective study of post-treatment 131I SPECT/CT imaging for personalizing therapy of patients with differentiated thyroid cancer by Sonya Sergieva, Teodor Sofiyanski, Bozhil Robev, Milena Dimcheva, Albena Fakirova

“…Conclusion: SPECT/CT improved the 131I WBS accuracy, thus changing the management of DTC determining indications for surgery, the need to give or withhold 131I therapy, and selecting cases for radiotherapy or chemotherapy in order to personalize the treatment.…”
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Unusual Presentation with Orbital Mass in a Child with Precursor B-Cell Acute Lymphoblastic Leukemia by Lalita Sathitsamitphong, Rungrote Natesirinilkul, Worawut Choeyprasert, Pimlak Charoenkwan

“…Chemotherapy with or without radiotherapy is generally suggested. The role of upfront hematopoietic stem cell transplantation remains inconclusive. …”
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Leiomyosarcoma of the Right Gonadal Vein: Review of the Approach and Prognostic in a Rare Case by Noa de la Fuente, Manuel Rodríguez Blanco, Gemma Cerdán, Antonio Moral, Vicenç Artigas

“…No chemotherapy or radiotherapy has yet proven effective in improving survival, and complete surgical excision is currently considered to offer the best chance of cure. …”
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Xerostomia: a silent burden for people receiving palliative care – a qualitative descriptive study by Emir Murphy Dourieu, Dominika Lisiecka, William Evans, Patricia Sheahan

“…Abstract Background The prevalence of dry mouth in the palliative care population is well documented and increases due to polypharmacy, radiotherapy and systemic conditions. Saliva as a lubricant for the mouth and throat has implications for swallowing, chewing, and speech. …”
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Management of asynchronous multifocal adult glioblastoma with loss of BRAFV600E -mutant clonality: a case report by Hannah Haile, Pavan S. Upadhyayula, Esma Karlovich, Michael B. Sisti, Brian J. A. Gill, Laura E. Donovan

“…Initial treatment involved surgical resection followed by radiotherapy and temozolomide (TMZ). Subsequent recurrences were managed with re-resection and dabrafenib/trametinib combination therapy. …”
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Radiosensitivity and Induction of Apoptosis by High LET Carbon Ion Beam and Low LET Gamma Radiation: A Comparative Study by Atanu Ghorai, Nitai P. Bhattacharyya, Asitikantha Sarma, Utpal Ghosh

“…Cancer treatment with high LET heavy ion beam, especially, carbon ion beam (12C), is becoming very popular over conventional radiotherapy like low LET gamma or X-ray. Combination of Poly(ADP-ribose) polymerase (PARP) inhibitor with xenotoxic drugs or conventional radiation (gamma or X-ray) is the newer approach for cancer therapy. …”
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Giant Prolactinoma of Young Onset: A Clue to Diagnosis of MEN-1 Syndrome by Chandrika Jayakanthi Subasinghe, Noel Somasundaram, Pathmanathan Sivatharshya, Lalana Devi Ranasinghe, Márta Korbonits

“…The female patient showed complete response to medical therapy, while the boy developed recurrent resistant prolactinoma needing surgery and radiotherapy. During follow-up, both developed pancreatic neuroendocrine tumours. …”
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Cancer vaccines: platforms and current progress by Wanting Lei, Kexun Zhou, Ye Lei, Qiu Li, Hong Zhu

“…The review further examines the synergistic potential of combining cancer vaccines with other therapies, such as chemotherapy, radiotherapy, and immune checkpoint inhibitors, to improve therapeutic outcomes. …”
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Organ-Preserving Surgery for Penile Carcinoma by Francisco E. Martins, Raul N. Rodrigues, Tomé M. Lopes

“…Penile carcinoma has traditionally been treated by either surgical amputation or radical radiotherapy, both associated with devastating anatomical, functional, and psychological impact on the patient's life. …”
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Primary Cutaneous Anaplastic Large Cell Lymphoma of the Oral Cavity Successfully Treated with Brentuximab Vedotin by Federico Meconi, Roberto Secchi, Raffaele Palmieri, Sara Vaccarini, Vito Mario Rapisarda, Laura Giannì, Fabiana Esposito, Ida Provenzano, Daniela Nasso, Livio Pupo, Maria Cantonetti

“…In this paper, we describe an unusual case of oral localization, recurring after skin-involving radiotherapy, successfully treated with sixteen cycles of brentuximab vedotin. …”
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Primary Spinal Germ Cell Tumors: A Case Analysis and Review of Treatment Paradigms by Joshua J. Loya, Henry Jung, Caroline Temmins, Nam Cho, Harminder Singh

“…We advocate limited volume radiotherapy combined with systemic chemotherapy in patients with high risk of recurrence. …”
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Sinonasal small-cell carcinoma combined concurrently with small-cell lung carcinoma: case report and literature review by Rencui Quan, Rencui Quan, Ling Han, Shihai Wu, Xianming Li

“…He received first-line platinum-doublet chemotherapy combined with durvalumab, followed by radiotherapy to thoracic as well as head and neck regions. …”
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Hypercalcemia in Lung Cancer due to Simultaneously Elevated PTHrP and Ectopic Calcitriol Production: First Case Report by Saed Nemr, Sunitha Alluri, Dhivya Sundaramurthy, Daniel Landry, Gregory Braden

“…A 60-year-old Caucasian male patient with stage IIIB squamous cell lung cancer developed hypercalcemia at 14.8 mg/dL two years after receiving chemotherapy and radiotherapy where labs showed a serum intact PTH: 7 pg/mL, PTHrP: 30 pmol/L, 1,25-hydroxyvitamin D (calcitriol): 76 pg/mL, and 25-hydroxyvitamin D levels: <4 ng/mL. …”
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Rare Encounter Behind the Ear: Unveiling Kimura Disease in the Postaural Region by Divya Nayani, Siddhartha Nyathani, Rahul Kumar Pitale Ashok

“…Treatment options encompass systemic steroids, antihistamines, immunosuppressants, chemotherapy, radiotherapy, and surgical excision. Despite interventions, the disease often locally recurs. …”
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Nano-Oncologic Vaccine for Boosting Cancer Immunotherapy: The Horizons in Cancer Treatment by Chao Chen, Yue Xu, Hui Meng, Hongyi Bao, Yong Hu, Chunjian Li, Donglin Xia

“…The combination therapy effects with photothermal therapy, radiotherapy, or immune checkpoint inhibitors are also discussed. …”
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The Efficacy and Safety of Lenalidomide plus Rituximab in an Orbital Relapse of Diffuse Large B-Cell Lymphoma by R. Palmieri, F. Esposito, F. Meconi, V. M. Rapisarda, L. Anemona, G. Paterno, S. Vaccarini, D. Nasso, L. Pupo, M. Cantonetti

“…In this experience, rituximab plus lenalidomide, without radiotherapy, was a safe and effective therapeutic combination in an elderly patient with a localized relapse of DLBCL who was unfit to receive more aggressive therapies.…”
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The Role of Gut Microbiota in Tumor Immunotherapy by Miao Wu, Jiawei Bai, Chengtai Ma, Jie Wei, Xianjin Du

“…Tumor immunotherapy is the fourth therapy after surgery, chemotherapy, and radiotherapy. It has made great breakthroughs in the treatment of some epithelial tumors and hematological tumors. …”
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A non-metallic PEEK topology optimization reconstruction implant for large mandibular continuity defects, validated using the MANDYBILATOR apparatus by Bram B. J. Merema, Frederik K. L. Spijkervet, Joep Kraeima, Max J. H. Witjes

“…This may potentially lead to optimised patient-specific reconstructions, with the implants matching the bone’s stiffness and possessing radiolucent properties which are useful for radiographic follow-ups and radiotherapy. Furthermore, the addition of the dynamic/cyclic MANDYBILATOR apparatus allows for more realistic application of the in-vivo loading of the mandible and can provide added insights in biomechanical behaviour of the mandible.…”
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The Effect of SP/NK1R on the Expression and Activity of Catalase and Superoxide Dismutase in Glioblastoma Cancer Cells by Faranak Korfi, Hossein Javid, Reza Assaran Darban, Seyed Isaac Hashemy

“…Glioblastoma is the most malignant brain tumor with different therapeutic protocols, including surgery, radiotherapy, and chemotherapy. Substance P (SP), a peptide released by sensory nerves, increases cellular excitability by activating the neurokinin-1 receptor (NK1R) in several human tumor cells. …”
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Artificial Neural Network-Based System for PET Volume Segmentation by Mhd Saeed Sharif, Maysam Abbod, Abbes Amira, Habib Zaidi

“…Tumour detection, classification, and quantification in positron emission tomography (PET) imaging at early stage of disease are important issues for clinical diagnosis, assessment of response to treatment, and radiotherapy planning. Many techniques have been proposed for segmenting medical imaging data; however, some of the approaches have poor performance, large inaccuracy, and require substantial computation time for analysing large medical volumes. …”
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