Current Trends in Targeted Therapies for Glioblastoma Multiforme by Fumiharu Ohka, Atsushi Natsume, Toshihiko Wakabayashi

“…Despite aggressive treatment including surgery, adjuvant TMZ-based chemotherapy, and radiotherapy, GBM still has a dismal prognosis: the median survival is 14.6 months from diagnosis. …”
Get full text

Extramedullary Plasmacytoma of the Oral Cavity: A Rare Case in the Buccal Mucosa by Armin Khaleghi, Nafise Shamloo

“…The lesion was treated successfully through a combination of surgical excision and radiotherapy at a dose of 40 Gy. This case underscores the importance of early diagnosis and treatment of EMP, particularly in rare locations, to prevent progression to MM and improve patient outcomes. …”
Get full text

Fluorescence-Guided Resection of Malignant Glioma with 5-ALA by Sadahiro Kaneko, Sadao Kaneko

“…In the future, chemotherapy with new anticancer agents, immunotherapy, and new methods of radiotherapy and gene therapy will be developed; however, ALA will play a key role in malignant glioma treatment before the development of these new treatments. …”
Get full text

An Osteolytic Metastasis of Humerus from an Asymptomatic Squamous Cell Carcinoma of Lung: A Rare Clinical Entity by Anirban Das, Sudipta Pandit, Sibes k. Das, Sumitra Basuthakur, Somnath Das

“…Systemic cytotoxic chemotherapy, local palliative radiotherapy, adequate analgesia, and internal fixation of the affected long bone are different modalities of treatment in this advanced stage of disease. …”
Get full text

A Rare Cause of the Cough: Primary Small Cell Carcinoma of Esophagus—Case Report by Erdal Yekeler, Timur Koca, Semra Vural

“…The case was assumed inoperable, and chemotherapy and radiotherapy were planned. We presented a rare cause of the cough and primary esophageal small cell carcinoma in this paper.…”
Get full text

A Narrative Review on the Pathophysiology and Management for Radiation Cystitis by C. Browne, N. F. Davis, E. Mac Craith, G. M. Lennon, D. W. Mulvin, D. M. Quinlan, Gerard P. Mc Vey, D. J. Galvin

“…Radiation cystitis is a recognised complication of pelvic radiotherapy. Incidence of radiation cystitis ranges from 23 to 80% and the incidence of severe haematuria ranges from 5 to 8%. …”
Get full text

Artificial intelligence across oncology specialties: current applications and emerging tools by Frank Lin, Tim Rattay, John Kang, Evangelia Katsoulakis, Kyle Lafata, Ellen Kim, Christopher Yao, Harsha Nori, Christoph Ilsuk Lee

“…In this review, we provide multidisciplinary perspectives on oncology applications touched by AI—imaging, pathology, patient triage, radiotherapy, genomics-driven therapy and surgery—and integration with existing tools—natural language processing, digital twins and clinical informatics.…”
Get full text

An Optimal Algorithm for Determining Risk Factors for Complex Diseases: Depressive Disorder, Osteoporosis, and Fracture in Young Patients with Breast Cancer Receiving Curative Surg... by Chieh-Yu Liu, Chun-Hung Chang

“…The results revealed that depressive disorder, osteoporosis, and fracture were clustered with liver cirrhosis, chronic obstructive pulmonary disease (COPD), distant metastasis, and primary metastatic and adjuvant therapies, namely, chemotherapy, radiotherapy, tamoxifen, aromatase inhibitors, and trastuzumab. …”
Get full text

Corrigendum: The role of dendritic cells in tertiary lymphoid structures: implications in cancer and autoimmune diseases by Mariana Reste, Kristi Ajazi, Ayca Sayi-Yazgan, Ayca Sayi-Yazgan, Radmila Jankovic, Biljana Bufan, Sven Brandau, Espen S. Bækkevold, Florent Petitprez, Malin Lindstedt, Gosse J. Adema, Catarina R. Almeida

Get full text

Enterovesical Fistula: A Rare Complication of Urethral Catheterization by Amr Hawary, Laurence Clarke, Alasdair Taylor, Peter Duffy

“…This report describes the case of an eighty-two-year old lady with an indwelling urethral catheter inserted eight years prior to her presentation to manage her urinary incontinence. She underwent radiotherapy for muscle-invasive bladder cancer (stage T2b) in 1991 and had a laparotomy and drainage of an appendicular abscess in her early twenties. …”
Get full text

Bilateral reconstruction of the mandibular body with symphyseal preservation using a single fibula free flap: operative technique by Riccardo Nocini, Vittorio Favero, Luigi Chiarini, Pier Francesco Nocini

“…Abstract Background Mandibular osteonecrosis may occur in 5% of the patients who undergo radiotherapy for the treatment of head and neck malignancies. …”
Get full text

Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients by Ayse Rabia Senkaya, Sercan Kantarci, Suna Yildirim Karaca, Muzaffer Sanci

“…Hemoglobin A1c levels and fasting glucose were compared with cancer stage, grade, histological type, lymphovascular invasion, chemotherapy and radiotherapy data. Results: A statistically significant difference was found between the groups in terms of HbA1c values only according to the lymphovascular invasion (p=0.02). …”
Get full text

Primary intracranial malignant melanoma in an adolescent: case report and literature review by Nyoman Golden, I Gusti Ketut Agung Surya Kencana, Christopher Lauren, Angky Saputra, Denny Japardi

“…The patient demonstrated no neurological deficits or seizures one year post-surgery and was managed with adjuvant radiotherapy. This report emphasizes the necessity of considering PIMM in differential diagnoses for seizures in young patients and highlights the importance of comprehensive diagnostic evaluations, including MRI and histopathology, in rare cases. …”
Get full text

Incisional Site Metastasis in a Patient with Cervical Carcinoma: A Case Report and Review of the Literature by C. Iavazzo, K. Madhuri, A. Tailor, S. Butler-Manuel

“…Wide excision was performed in 30/37 cases of which we have information regarding the treatment option, while 11/37 and 13/37 underwent radiotherapy and chemotherapy, respectively. The possible mechanism of such a metastasis as well as the treatment options is discussed.…”
Get full text

DNA Vaccination: Using the Patient's Immune System to Overcome Cancer by Georg Eschenburg, Alexander Stermann, Robert Preissner, Hellmuth-Alexander Meyer, Holger N. Lode

“…Optimization of standard treatment protocols consisting of the main columns of chemo- and radiotherapy followed or preceded by surgical intervention is often limited by toxic side effects and induction of concomitant malignancies and/or development of resistant mechanisms. …”
Get full text

Corticosteroids and Azathioprine Do Not Prevent Radiation-Induced Lung Injury by Eva Kwok, Charles K Chan

“…The case of a man who presented with dyspnea and a dry cough six weeks after mediastinal radiotherapy for malignant thymoma is described. The patient was on prednisone (30 mg/day) and azathioprine (100 mg/day) throughout the course of radiation. …”
Get full text

Diagnosis and Treatment of Bone Disease in Multiple Myeloma: Spotlight on Spinal Involvement by Patrizia Tosi

“…Multiple treatment modalities can be used to manage multiple myeloma-related vertebral lesions. Surgery or radiotherapy is mainly employed in case of spinal cord compression, impending fractures, or intractable pain. …”
Get full text

The characteristics of the tumor immune microenvironment in colorectal cancer with different MSI status and current therapeutic strategies by Qingzhe Wang, Min Yu, Shuang Zhang

“…Despite advancements in surgery, chemotherapy, and radiotherapy, the effectiveness of these conventional treatments is limited, particularly in advanced cases. …”
Get full text

Solitary Plasmacytoma of the Mesentery: A Systematic Clinician’s Diagnosis by Georgia Mitropoulou, Adamantia Zizi-Sermpetzoglou, Hippokrates Moschouris, Athanasios Kountourogiannis, Despoina Myoteri, Dionysios Dellaportas

“…The patient underwent definitive radiotherapy and remains under remission one year later. …”
Get full text

Brachytherapy for Prostate Cancer: A Systematic Review by Georgios Koukourakis, Nikolaos Kelekis, Vassilios Armonis, Vassilios Kouloulias

“…Patients with localized prostate cancer may benefit from high-dose-rate brachytherapy, which may be used alone in certain circumstances or in combination with external-beam radiotherapy in other settings. The purpose of this paper is to present the essentials of brachytherapies techniques along with the most important studies that support their effectiveness in the treatment of prostate cancer.…”
Get full text