Resection and Reconstruction of Maxillary Class IIIc Defect in a Case of Adenoid Cystic Carcinoma: Cost-Sensitive Technique without Microvascular Grafts by Dwarkadas Adwani, Anirudh Bhattacharya, Rajender Singh Arora, Ramawatar Soni, Nitin Adwani

“…The treatment of choice consists of wide radical resection of the tumor followed by radiotherapy. Rehabilitation options in cases with huge maxillary defects still need further exploration.…”
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A Case Report of Leptomeningeal Myelomatosis and Rapid Improvement with Regimen Consisting of Daratumumab, Pomalidomide, Vincristine, Procarbazine, and Dexamethasone by Jew Win Kuan, Sing Ling Chai, Pathmanathan Rajadurai, Lee Gong Lau, Joseph Uchang, Sharifah Noor Akmal Syed Husain

“…A 61-year-old man was diagnosed with MM with left paravertebral plasmacytoma, R-ISS II with high suspicion of double-hit MM, either biallelic aberrancy of TP53 or del(17p) and IGH aberrancy depending on the definition chosen, treated with lenalidomide-bortezomib-dexamethasone and local radiotherapy, later developed systemic relapse and progression to MM-CNS in the form of leptomeningeal myelomatosis. …”
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Genetic and Molecular Biology Implications in the Surgical Treatment of Gastric Cancer by Roberto Eduardo Aguirre Fernández, Miguel Ángel Serra Valdés

“…Current clinical practice guidelines offer treatment models that involve surgery, radiotherapy, chemotherapy, immunotherapy and therapy directed at specific growth receptors, however, genetic and molecular biology aspects are not always taken into account in medical practice. …”
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Patient-Tailored, Imaging-Guided, Long-Term Temozolomide Chemotherapy in Patients with Glioblastoma by Norbert Galldiks, Lutz W. Kracht, Lothar Burghaus, Roland T. Ullrich, Heiko Backes, Anna Brunn, Wolf-Dieter Heiss, Andreas H. Jacobs

“…We present two patients with glioblastoma with an unusually stable clinical course and long-term survival who were treated after surgery and radiotherapy with adjuvant temozolomide (TMZ) chemotherapy for 17 and 20 cycles, respectively. …”
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Chondroid Chordoma and Nasal Adenocarcinoma: An Exceptional Association by Patrice Gallet, Nathalie Marcon, Thomas Georgel, Jean-Marie Vignaud, Cécile Parietti-Winkler, Roger Jankowski

“…The treatment consisted of endoscopic endonasal surgery followed by conventional radiotherapy. After 18 months, a local recurrence was diagnosed after a facial trauma, but the true histology was difficult to assess. …”
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Diffuse Neurofibroma in a Patient with Unknown History of NF1 by Mahmoud A. K. Ebrahim, Mishal M. AlMutairi, Khaled M. Hindi, Jassem M. Bastaki

“…The patient, who exhibited clinical features compatible with (NF1), proceeded for radiotherapy following surgery to continue his treatment.…”
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A Bayesian Hierarchical Model for Relating Multiple SNPs within Multiple Genes to Disease Risk by Lewei Duan, Duncan C. Thomas

“…The method is applied to data on 504 SNPs in 38 candidate genes involved in DNA damage response in the WECARE study of second breast cancers in relation to radiotherapy exposure.…”
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From Global Insights to National Impact: Advancing Cardio-Oncology in Iraq by Mustafa H. Ajlan, Hasan A. Farhan, Zainab A. Dakhil

“…., checkpoint inhibitors, gene-targeted therapies), antibody-based cancer toxins, chemotherapy, radiotherapy, and surgery—have significantly improved survival rates 1,2. …”
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The ketogenic diet as a promising adjunctive therapy for glioma: a comprehensive review by Arman Hamzei, Sara Hallaji, Seyed Farzin Hosseini, Arman Keymoradzadeh

“…In recent decades, there's been a growing trend to replace or combine radiotherapy with chemotherapy, targeted therapy, and personalized treatment for different patients. …”
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ALA photodynamic therapy combined with dual 980nm/1470nm diode laser for classic Kaposi's sarcoma by Yajing Cao, Dixin Wang, Yeqiang Liu, Linglin Zhang, Xiuli Wang

“…The combination of the dual 980nm/1470 nm diode laser and ALA-PDT may be astrategy in treating local KS with good tolerance, especially in elder patients who can not tolerate radiotherapy and chemotherapy.…”
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Metastatic SQSTM1-NTRK1 fused non-small-cell lung cancer treated with larotrectinib and stereotactic radiosurgery resulting in durable complete response: a case report by Colton Betts, Ari Kassardjian, Arya Amini

“…We present the case of a patient who was diagnosed with SQSTM1-NTRK1 fused NSCLC with polymetastatic disease involving the brain and subsequently treated with a multidisciplinary approach via neurosurgical resection, radiotherapy, and larotrectinib. The combination of aggressive local treatments and systemic therapy is a relatively new treatment paradigm and represents a new area of research to optimize local control of metastatic lesions and potentially improve progression-free survival compared to the trials that show the efficacy of systemic monotherapies. …”
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Insights into Cancer-Associated Thrombosis Leading Towards Ischemic Stroke by Surajit Hansda, Hiranmoy Das

“…Treatment methods for cancer, including chemotherapy, radiotherapy, and surgery, have all been demonstrated to increase the risk of stroke as well. …”
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Adenoid Cystic Carcinoma of the Bartholin’s Gland: A Diagnostic Dilemma by Charmaine C. W. Lo, Jerome B. Y. Leow, K. Naing, Ken Jaaback, Thanuja Thachil

“…She was subsequently treated with wide local excision of the primary and inguinal lymph node dissection followed by adjuvant radiotherapy and chemotherapy. She had gross perineural invasion on MRI imaging. …”
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Predicting Residual Rectal Adenocarcinoma in the Surgical Specimen after Preoperative Brachytherapy with Endoscopic Ultrasound by Joseph Romagnuolo, Josée Parent, Té Vuong, Mélanie Bélanger, René P Michel, Paul J Belliveau, Judith L Trudel

“…However, external beam radiotherapy appears to decrease the accuracy of EUS from 85% to 40%. …”
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Laryngeal Synovial Sarcoma: A Rare Clinical Entity by Clair Saxby, Ron Bova, Melanie Edwards

“…The patient received adjuvant chemotherapy followed by a course of radiotherapy and remains alive and disease free at 18 months after treatment. …”
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A Review on the Application of PD-1 Blockade in EBV-Associated Nasopharyngeal Carcinoma Immunotherapy by Jin Bian, Yan Niu, Yanli Ma, Fuhua Chen, Ning Ma

“…Epstein-Barr virus (EBV) linked with nasopharyngeal carcinoma (NPC) is considered to be one of the most prevalent head and neck malignancies in East and Southeast Asia. Although radiotherapy and chemotherapy are effective treatments for NPC, they have immunosuppressive effects. …”
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Adaptive Treatment of Metastatic Prostate Cancer Using Generative Artificial Intelligence by Youcef Derbal

“…Testosterone and prostate-specific antigen (PSA) are assumed to be repeatedly monitored while treatment may involve a combination of androgen deprivation therapy (ADT), androgen receptor-signalling inhibitors (ARSI), chemotherapy, and radiotherapy. The analysis covers various questions relevant to the configuration, training, and inferencing of GPTs for the case of mPC treatment with a particular attention to risk mitigation regarding the hallucination problem and its implications to clinical integration of GenAI technologies. …”
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Multifunctional Synthetic Poly(-Glutamic Acid)–Based Cancer Therapeutic and Imaging Agents by Marites P. Melancon, Chun Li

“…This review summarizes and updates our recent research on the use of PG as a platform for drug delivery and molecular imaging, including recent clinical findings with respect to PG-paclitaxel (PG-TXL), the combination of PG-TXL with radiotherapy, mechanisms of action of PG-TXL, and noninvasive visualization of in vivo delivery of polymeric conjugates with contrast-enhanced magnetic resonance imaging, optical imaging, and multimodality imaging.…”
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Controversies in the Management of Endometrial Cancer by V. Masciullo, G. Amadio, D. Lo Russo, I. Raimondo, A. Giordano, G. Scambia

“…This review summarizes the management of EC and discusses current controversies regarding the role of lymphadenectomy and radiotherapy in patients with intermediate-risk tumors confined to the uterus.…”
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Advancements in targeted and immunotherapy strategies for glioma: toward precision treatment by Guangyuan Gong, Lang Jiang, Jing Zhou, Yuanchao Su

“…High-grade gliomas (HGGs), characterized by their high malignancy, remain challenging to treat despite standard treatment regimens, including surgery, radiotherapy, chemotherapy, and tumor treating fields (TTF). …”
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