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4-1BB agonist targeted to fibroblast activation protein α synergizes with radiotherapy to treat murine breast tumor models
Published 2025-02-01“…Background Ionizing radiation (IR) is a double-edged sword for immunotherapy as it may have both immunosuppressive and immunostimulatory effects. …”
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Characteristics of the smallest brucellaphage with strong lytic ability
Published 2025-02-01“…It exhibits broad pH and temperature stability, retaining activity even after 1 h of exposure to ultraviolet radiation and various ethanol concentrations. Y17 shows strong lytic activity against Brucella abortus and can also infect some Brucella melitensis strains. …”
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A pelvis MR transformer-based deep learning model for predicting lung metastases risk in patients with rectal cancer
Published 2025-02-01“…Utilizing MR images to classify RCLM could potentially reduce ionizing radiation exposure and the costs associated with chest CT in patients without metastases. …”
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3546
Evaluation of the WRF-Chem performance for the air pollutants over the United Arab Emirates
Published 2025-02-01“…The model also overestimated incoming shortwave radiation by <span class="inline-formula">∼</span> 30 W m<span class="inline-formula"><sup>−2</sup></span> in December due to reduced cloud cover. …”
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Causes of growing middle-to-upper tropospheric ozone over the northwest Pacific region
Published 2025-01-01“…<p>Long-term ozone (O<span class="inline-formula"><sub>3</sub></span>) changes in the middle-to-upper troposphere are critical to climate radiative forcing and tropospheric O<span class="inline-formula"><sub>3</sub></span> pollution. …”
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Effects of Climatic Conditions and Agronomic Practices on Health, Tuber Yield, and Mineral Composition of Two Contrasting Potato Varieties Developed for High and Low Input Producti...
Published 2024-12-01“…Results from both ANOVA and redundancy analysis (RDA) indicate that the effects of climatic (precipitation, radiation, and temperature) and agronomic (fertilization and crop protection) explanatory variables on crop health and yield differed considerably between the two varieties. …”
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Design, evaluation, and future projections of the NARCliM2.0 CORDEX-CMIP6 Australasia regional climate ensemble
Published 2025-02-01“…We first describe NARCliM2.0's design, including selecting two definitive RCMs via testing 78 RCMs using different parameterisations for the planetary boundary layer, microphysics, cumulus, radiation, and land surface model (LSM). We then assess NARCliM2.0's skill in simulating the historical climate versus CMIP3-forced NARCliM1.0 and CMIP5-forced NARCliM1.5 RCMs and compare differences in future climate projections. …”
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Research on Characteristics and Influencing Factors of High Temperature Disaster Risk in Wuhan Based on Local Climate Zone
Published 2025-01-01“…Among the natural environment types, water area (LCZ G) has the lowest average value of high temperature disaster risk, which indicates that water can effectively mitigate the risk of high temperature disaster; while for bare rock (LCZ E), exposed sand (LCZ F), and construction building (LCZ H) exposed outdoor, they typically have higher values of high temperature disaster risk due to solar radiation for a long time. As to landscape pattern indices, the area percentage of landscape (PLAND) has a higher influence on high temperature disaster risk than aggregation index (AI).ConclusionBased on the research results above, strategies to cope with high temperature disasters are proposed. …”
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Experimental analysis of micro-cavity influence on the effective solar absorptance of white sand curtain on porous obstructions of particle heating receivers
Published 2025-02-01“…Within this curtain, micro-cavities are generated, which dramatically reduce radiation loss to the sky by facilitating multiple reflections, effectively trapping intercepted rays, and thereby maximizing solar absorptance. …”
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Tungsten impurity reduction by ICRH in a high power injection and high performance H-mode discharge on EAST
Published 2025-01-01“…In addition, the poloidal asymmetry of radiation distribution from the tomographic inversions of Soft x-ray emission is reduced obviously. …”
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Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway
Published 2025-02-01“…The mice were exposed to 0.4 W/cm2 intensity ultrasonic radiation for 15 min at 4 h post injection of sinoporphyrin sodium (DVDMS) (4 mg/kg) into the caudal vein was repeated weekly for 4 treatments. …”
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Therapeutic benefit of the dual ALK/FAK inhibitor ESK440 in ALK-driven neuroblastoma
Published 2025-02-01“…Standard therapy involves highly toxic chemotherapy, surgery, radiation, and immunotherapy, and less toxic, more specific targeted therapies are urgently needed. …”
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Studying the Oncolytic Activity of <i>Streptococcus pyogenes</i> Strains Against Hepatoma, Glioma, and Pancreatic Cancer <i>In Vitro</i> and <i>In Vivo</i>
Published 2025-01-01“…Conventional treatment modalities, including radiation and chemotherapy, often fall short of achieving complete remission, highlighting the critical need for novel therapeutic strategies. …”
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