Implementing a Care Model for Bedridden Stroke Survivors: A Qualitative Study in Northeastern Thailand by Panpanit L, Jongudomkarn D, Doungmungkorn A, Boontoch K, Neelasmith S, Manorat M, Maneerat T

“…Despite investments in stroke prevention, inadequate support exists for severely disabled stroke survivors (SSs) and their caregivers, particularly in enhancing their quality of life.Purpose: This research aimed to explore the experiences of SSs receiving home care, develop and implement a care model to enhance community volunteer caregivers’ (CVCGs) capabilities, and evaluate the outcomes of this model for bedridden stroke survivors in Northeastern Thailand.Methods: A research and development study was conducted in low-income, semi-urban communities in Northeastern Thailand, comprising three phases: 1) situation analysis, 2) development of a community care model, and 3) implementation and evaluation. …”
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Trifluridine/tipiracil regimen in combination with bevacizumab for metastatic colorectal cancer in the third line: an expert opinion by Carmine Pinto, Sara Lonardi, Evaristo Maiello, Erika Martinelli, Michele Prisciandaro, Lisa Salvatore, Lisa Salvatore, Andrea Sartore-Bianchi, Andrea Sartore-Bianchi, Mario Scartozzi, Giuseppe Aprile, Chiara Cremolini, Alberto Sobrero

“…The prolongation of survival along with the preservation of quality of life, possibly avoiding harmful cumulative toxicities, is the primary therapeutic aim for patients with metastatic colorectal cancer (mCRC) in the third-line setting. …”
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Support Needs of Patients with Cushing’s Disease and Cushing’s Syndrome: Results of a Survey Conducted in Germany and the USA by Ilonka Kreitschmann-Andermahr, Sonja Siegel, Christa Gammel, Karen Campbell, Leslie Edwin, Agnieszka Grzywotz, Victoria Kuhna, Maria Koltowska-Häggström, Oliver Müller, Michael Buchfelder, Bernadette Kleist

“…In view of the high disease burden of CD/CS patients and long-term impaired quality of life, the present survey was conducted to gain information about subjective illness distress and patients’ specific needs in terms of supportive measures beyond medical interventions. …”
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Risk factors for and incidence of osteoporosis in patients with breast cancer by gender : a nationwide cohort study by Jin Ah Lee, Hye Sun Lee, Soyoung Jeon, Dooreh Kim, YoungJoo Lee, SooYun Bae, Woo-Chan Park, Chang Ik Yoon

“…Our study highlights gender-specific risks for osteoporosis and fractures in breast cancer patients, contributing to a comprehensive understanding for improving long-term outcomes and quality of life in survivors.…”
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Structured follow-up pathway to support people after transient ischaemic attack and minor stroke (SUPPORT TIA): protocol for a feasibility study and process evaluation by Grace M Turner, Melanie Calvert, Sue Jowett, Robbie Foy, Jonathan Mant, Sarah Tearne, Lou Atkins, Rachael Jones, Smitaa Patel, Phillip Collis

“…Follow-up questionnaires will measure anxiety, depression, fatigue, health related quality of life, self-efficacy and medication adherence. …”
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Glu4: An open-source package for real-time forecasting and alerting post-bariatric hypoglycemia based on continuous glucose monitoring by Luca Cossu, Francesco Prendin, Giacomo Cappon, David Herzig, Lia Bally, Andrea Facchinetti

“…By improving safety and quality of life for individuals with PBH, Glu4 addresses a critical unmet need. …”
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Chemokine Profiles Are Affected in Serum of Patients with Acute Rejection of Kidney Allograft by Lenka Krupickova, Martina Fialova, Marek Novotny, Veronika Svachova, Kristyna Mezerova, Eva Cecrdlova, Ondrej Viklicky, Ilja Striz

“…Kidney allograft transplantation improved the prognosis and quality of life of patients with end-stage renal diseases but the occurrence of acute rejection represents a limitation of the final outcome. …”
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Cost-Effectiveness of Bariatric Surgery versus Medication Therapy for Obese Patients with Type 2 Diabetes in China: A Markov Analysis by Bin Wan, Nan Fang, Wei Guan, Haixia Ding, Ying Wang, Xin Ge, Hui Liang, Xin Li, Yiyang Zhan

“…A Markov model was established to compare the 40-year time costs and quality-adjusted life-years (QALYs) between bariatric surgery and medication therapy. …”
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Development and Characterization of a Hydrogel Containing Chloramphenicol-Loaded Binary Ethosomes for Effective Transdermal Permeation and Treatment Acne in Rat Model by Liu RJ, Li M, Zhu Q, Liu HY, Zhang XX, Han XY, Yu MJ, Zhou JW, Han CY

“…Run jia Liu,1 Miao Li,1 Qian Zhu,1 Hui ying Liu,1 Xing xiu Zhang,1 Xiang yuan Han,1 Meng jun Yu,1 Jian wen Zhou,2 Cui yan Han1 1School of Pharmacy, Qiqihar Medical University, Qiqihar, People’s Republic of China; 2Institute of Medicine and Drug Research, Qiqihar Medical University, Qiqihar, People’s Republic of ChinaCorrespondence: Cui yan Han, School of Pharmacy, Qiqihar Medical University, Qiqihar, People’s Republic of China, Tel/Fax +86-24-2663822, Email hcymuphar@qmu.edu.cnPurpose: Acne is a serious disfiguring follicular sebaceous gland disorder that negatively affects patients’ quality of life and self-image. Chloramphenicol (CAM) is effective against Propionibacterium acnes and Staphylococcus aureus which cause acne, often used as a hospital preparation for acne treatment. …”
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Relative Fat Mass and Physical Indices as Predictors of Gallstone Formation: Insights From Machine Learning and Logistic Regression by Deng L, Wang S, Wan D, Zhang Q, Shen W, Liu X, Zhang Y

“…Laifu Deng,1,* Shuting Wang,1,* Daiwei Wan,1,* Qi Zhang,2 Wei Shen,1 Xiao Liu,1,* Yu Zhang1,* 1Department of General Surgery, Wuxi Medical Center of Nanjing Medical University, Wuxi, People’s Republic of China; 2Department of Oncology, Tengzhou Central People’s Hospital, Jining Medical College, Shandong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiao Liu; Yu Zhang, Department of General Surgery, Wuxi Medical Center of Nanjing Medical University, Wuxi, People’s Republic of China, Tel +8613561164619 ; +8613793706777, Email ningzhouwxrmyy@163.com; yuzhangjs@yeah.netPurpose: Gallstones (GS), a prevalent disorder of the biliary tract, markedly impair patients’ quality of life. This study aims to construct predictive models employing diverse machine learning algorithms to elucidate risk factors linked to gallstone formation.Patients and Methods: This study integrated data from the National Health and Nutrition Examination Survey (NHANES) with a cohort of 7868 participants from Wuxi People’s Hospital and Wuxi Second People’s Hospital, including 830 individuals diagnosed with gallstones. …”
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Long-Term Outcomes of Mechanical Thrombectomy for Stroke: A Meta-Analysis by David J. McCarthy, Anthony Diaz, Dallas L. Sheinberg, Brian Snelling, Evan M. Luther, Stephanie H. Chen, Dileep R. Yavagal, Eric C. Peterson, Robert M. Starke

“…There was a significant difference between the 2 arms in favor of endovascular therapy for the quality of life at long-term follow-up (mean difference 0.11; p = 0.0002). …”
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Development of a patient reported outcome instrument for chronic sialadenitis by Fatemeh Ramazani, Amr Hamour, Caroline C. Jeffery, Vincent Biron, Yaser Alrajhi, Daniel O’Connell, David W. J. Côté

“…Clinicians report improved patient quality of life (QoL) following sialendoscopy assisted treatments, but there exist gaps in current literature about patient reported outcomes (PROs). …”
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Systematic review and meta-analysis on the prevalence and risk factors of oral frailty among older adults by Pingping Huang, Linjing Wu, Rongxiang Zhang, Rongxiang Zhang, Shiqi Chen, Shiqi Chen, Yu Zhang, Yuan Chen, Yuan Chen

“…Such proactive efforts are essential for early identification of high-risk individuals, which can help reduce the prevalence of oral frailty among older adults and enhance their quality of life.Systematic Review RegistrationPROSPERO (CRD42023488653: https://www.crd.york.ac.uk/prospero/).…”
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Evaluation of 902 Total Abdominal Hysterectomies Performed for Benign Reasons by Fazilet Kübra Boynukalın, Ömer Tolga Güler, Mehmet Coşkun, Özgür Özyüncü, Nasuh Utku Doğan

“…CONCLUSION: Abdominal hysterectomy, the most frequently performed operation of gynecology clinics, is an effective treatment modality in relieving symptoms and increasing quality of life with relatively lower complication rates. …”
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Are breast cancer patients with low distress at diagnosis at risk of psychological symptoms later in their disease trajectory? Considerations for when to screen for distress by Rikke Langballe, Birgitte Mertz, Niels Kroman, Thomas Maltesen, Susanne Rosthøj, Pernille Envold Bidstrup

“…We used latent class mixed models to identify sub-groups of patients with similar development in distress, anxiety, depression, breast cancer-specific health-related quality of life, self-efficacy, and fear of recurrence over time. …”
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The prevention opportunities of retinopathy in diabetic patients – position paper endorsed by the Polish Lipid Association by Maciej Banach, Stanisław Surma, Grzegorz Dzida, Jacek Jóźwiak, Bogusław Okopień, Jacek Rysz, Konrad Szosland, Andrzej Grzybowski

“…In this Position Paper by the Polish Lipid Association (PoLA) we have reviewed the current stage of knowledge on possible mechanisms by which fenofibrate may contribute to retinopathy prevention, available data on safety and efficacy, to finally recommend administering fenofibrate in prevention of this dangerous diabetic complication, which significantly affects quality of life and disability-adjusted life-years (DALY). …”
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Increasing the uptake of long-acting reversible contraception in general practice: the Australian Contraceptive ChOice pRoject (ACCORd) cluster randomised controlled trial protocol by Danielle Mazza, Angela Taft, Kevin McGeechan, Kirsten Black, Heather McKay, Marion Haas, Jayne Lucke, Jeffery F Peipert

“…The primary outcome will be the number of LARCs inserted; secondary outcomes include the women's choice of contraceptive method and quality of life (Short Form Health Survey, SF-36). The costs and outcomes of the intervention and control will be compared in a cost-effectiveness analysis.Ethics and dissemination The ACCORd study has been approved by the Monash University Human Research Ethics Committee: CF14/3990-2014002066 and CF16/188-2016000080. …”
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Laryngeal cancer diagnosis based on improved YOLOv8 algorithm by Xin Nie, Xueyan Zhang, Di Wang, Yuankun Liu, Lumin Xing, Wenjian Liu

“…Enhancing the diagnosis and treatment of laryngeal cancer can significantly improve patients’ prognosis and quality of life. Artificial intelligence (AI) technology shows promise as a valuable tool for diagnosing laryngeal cancer. …”
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Digital Health Program to Support Family Caregivers of Children Undergoing Growth Hormone Therapy: Qualitative Feasibility Study by Alba Jiménez-Díaz, Maitena Pierantonelli, Patricia Morte Coscolín, Amaia Salinas-Uhalte, Silvia Quer-Palomas, Octavio Rivera-Romero, Rocío Herrero, Luis Fernández-Luque, Rosa Baños, Ricardo C Berrios, Antonio de Arriba

“…This psychological burden might affect children’s adherence to treatment and hinder their health-related quality of life (HrQoL). This assumption is leading to seriously considering multidimensional clinical approaches to pediatric health conditions where the emotional well-being of caregivers should be accounted for to optimize children’s health outcomes. …”
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Pectus Carinatum Repair Using the Sandwiched Bars and Screw Fixation System: A Retrospective Cohort Study of a Single Center Experience by Tran Thanh Vy, Ho Tat Bang, Ha Quoc Hung, Lam Thao Cuong, Nguyen Hoang Binh

“…ABSTRACT Background and Aims Pectus carinatum (PC) is the second most common deformity of the anterior chest wall, resulting in detrimental effects on body image and quality of life. This study evaluated the safety, effectiveness, and factors associated with the treatment of PC using a sandwiched bar and screw fixation system, first performed in Vietnam at the University Medical Center Ho Chi Minh City in 2016. …”
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