Ellis-van Creveld Syndrome: Mutations Uncovered in Lebanese Families by Maria Valencia, Lara Tabet, Nadine Yazbeck, Alia Araj, Victor L. Ruiz-Perez, Khalil Charaffedine, Farah Fares, Rebecca Badra, Chantal Farra

“…While more research is required to explore other genes involved in EvC, early diagnosis and therapeutic care are important to achieve a better quality of life.…”
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Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives by Dong Luo, Yunmei Liu, Zhengmao Lu, Lei Huang

“…Clinical trials have supported that targeted therapy and immunotherapy can significantly improve the survival and quality of life of GC patients. However, the effects of such therapies need to be further improved and more personalized, with advancement in researches on tumor immune microenvironment. …”
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Alteration of Mastication Force via Intraoral Closed-Loop Electrical Stimulation by Junxiang Zheng, Bing Jiang, Saurabh Biswas, Su Young Lee, Erin Ealba Bumann, Teresa E. Lever, Jeonghee Kim, Hangue Park

“…Therefore, regulating masticatory force in people with declining mastication function is significant for maintaining health and quality of life. In this study, we tested the effect of tactile augmentation on mastication force. …”
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Cost Effectiveness of Insulin Glargine versus Neutral Protamin Hagedorn Insulin in the Treatment of Type 2 Diabetes Patients in Turkey by Ilhan Satman, Hayley Bennett, Candeger Yilmaz, Sazi Imamoglu, Goksun Ayvaz, Abdurrahman Comlekci, Demet Ozkaya, Toros Sahin

“…**Results:** Over a lifetime, the Incremental Cost-effectiveness Ratio (ICER) of insulin glargine compared to NPH was 40,101 TL per Quality-adjusted Life Year (QALY). Almost 52 hypoglycaemic events per patient were avoided with the use of insulin glargine compared to NPH, at an incremental lifetime cost of 7,140 TL per patient. …”
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Changes in tear cytokine and lactoferrin levels in postmenopausal women with primary acquired nasolacrimal duct obstruction complicated with obstructed meibomian gland dysfunction by Haili Jin, Xianjie Chen, Feng Ji, Yin Liu, Yonghong Sheng, Guoping Wang, Linfeng Han, Xiaohu Wang, He Ding, Jing Liu, Qingqing Fu

“…Abstract Background Epiphora and secondary ocular surface damage are increasingly impairing the quality of life of people, particularly elderly women. …”
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Perceived costs and benefits of companion dog keeping based on a convenience sample of dog owners by Laura Gillet, Borbála Turcsán, Eniko Kubinyi

“…However, the psychological and practical demands of caring for a dog can significantly impact the owner’s quality of life and the long-term success of the dog-owner relationship. …”
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A Prospective Study of Lumbar Facet Arthroplasty in the Treatment of Degenerative Spondylolisthesis and Stenosis: Early Cost-effective Assessment from the Total Posterior Spine Sys... by Jared D. Ament, Amir Vokshoor, Yaser Badr, Todd Lanman, Kee D. Kim, J. Patrick Johnson

“…Secondary outcomes were health-related utility, presented as quality-adjusted life-years (QALYs), and cost, calculated in US dollars. …”
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Evaluating the Real-World Effectiveness of Systemic Treatments in Atopic Dermatitis Using the Atopic Dermatitis Control Tool (ADCT): A Multi-Centre, Prospective Study by Hyun Ji Lee, Yuri Woo, Young Bok Lee, Ji Hye Lee, Jung Eun Kim, Ji Hyun Lee, Sang Hyun Cho

“…Atopic dermatitis is a chronic skin disease affecting quality of life, sleep, and mental health. Traditional evaluation methods focus on clinical assessments, but there is a growing need for tools that incorporate patient-reported outcomes (PROs). …”
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An X-Linked Hyper-IgM Patient Followed Successfully for 23 Years without Hematopoietic Stem Cell Transplantation by Necil Kutukculer, Neslihan Edeer Karaca, Guzide Aksu, Ayca Aykut, Erhan Pariltay, Ozgur Cogulu

“…When caring for patients with life-limiting diseases, improving survival and optimizing quality of life are the primary goals. For patients with X-linked hyper-IgM syndrome (XHIGM), the treatment modality has to be decided for a particular patient regarding hematopoietic stem cell transplantation or intravenous immunoglobulin replacement therapy with P. jiroveci prophylaxis. …”
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Diagnosis and Treatment of Elderly and Senile Chronic Constipation: an Expert Consensus by V. T. Ivashkin, M. G. Mnatsakanyan, V. S. Ostapenko, А. P. Pogromov, V. M. Nekoval, E. A. Poluectova, Yu. V. Kotovskaya, N. K. Runikhina, N. V. Sharashkina, P. V. Tsarkov, N. O. Tkacheva, Yu. N. Belenkov

“…Chronic constipation is associated with a higher risk of cardiovascular disease and complications, impaired general perception of health and pain, growing alarm and depression, and reduced quality of life. The treatment tactics in chronic constipation is cause-conditioned and should account for the patient’s history and therapy line, overall clinical condition, cognitive status and functional activity level. …”
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Construction and application of a stratified nursing intervention program for postoperative delirium after Stanford type A aortic dissection: a quasi-experimental trial by Xueping Li, Miaomiao Zheng, Ailin Lin, Chaohong Chen, Yuanbo Wu, Huai Zhang, Zhiqin Yin

“…Conclusion Implementing this nurse intervention in the ward context can shorten postoperative delirium and hospital stays, increase patient satisfaction with care, and improve patient prognosis and quality of life. This intervention will also serve as a great resource for future clinical management of postoperative delirium. …”
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Cluster randomised controlled trial on the effects of long-term home-based exercise for patients with chronic obstructive pulmonary disease with recent exacerbation: research proto... by Ulla Møller Weinreich, Lars Pilegaard Thomsen, Jane Andreasen, Anna Lei Stoustrup, Thorvaldur S Palsson

“…Primary outcome is physical performance, while secondary outcomes include daily activity levels, lung function, mobility, frailty, symptom severity, health-related quality of life, survival rates and readmissions. A qualitative substudy will uncover experiences from participants. …”
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No Difference in Hip Muscle Volumes and Fatty Infiltration in Those With Hip-Related Pain Compared to Controls by Timothy H Retchford, Kylie J Tucker, Harvi F Hart, Adam I Semciw, Patrick Weinrauch, Alison Grimaldi, Sallie M Cowan, Kay M Crossley, Joanne L Kemp

“… # Study Design Cross-sectional study # Methods Muscle volume and fatty infiltrate (from magnetic resonance imaging), hip muscle strength, patient-reported symptoms, function and quality of life (QOL) were determined for 16 participants with hip-related pain (no clinical signs of FAIS; 37±9 years) and 15 controls (31±9 years). …”
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Autoimmune Complications after Hematopoietic Stem Cell Transplantation in Children with Nonmalignant Disorders by Abdalla Khalil, Irena Zaidman, Reuven Bergman, Ronit Elhasid, Myriam Weyl Ben-Arush

“…The potential to identify risk factors for AICs could lead to less morbidity and mortality and to maintain the patient’s quality of life.…”
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State of the Art Compendium: Canadian Thoracic Society Recommendations for Management of Chronic Obstructive Pulmonary Disease by Denis E O’Donnell, Shawn Aaron, Jean Bourbeau, Paul Hernandez, Darcy Marciniuk, Meyer Balter, Gordon Ford, Andre Gervais, Roger Goldstein, Rick Hodder, Francois Maltais, Jeremy Road

“…Management strategies, consisting of combined modern pharmacotherapy and nonpharmacotherapeutic interventions (eg, pulmonary rehabilitation and exercise training) can effectively improve symptoms, activity levels and quality of life, even in patients with severe COPD.…”
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Occupational burn-out, fatigue and stress in professional rescuers: a cross-sectional study in Kazakhstan by Denis Vinnikov, Zhangir Tulekov, Gulnara Kapanova, Zhanna Romanova, Ilya Krugovykh, Sundetgali Kalmakhanov, Aliya Ualiyeva, Kaini Baigonova, Damet Ongarbaeva

“…Objectives To find predictors of burn-out in a cohort of rescuers.Design Cross-sectional study.Setting Republican Rescue Squad (N=105) and Republican Mudslide Rescue Service under the Ministry of Emergency Situations (N=480) in Almaty, Kazakhstan.Participants In total, we included 268 (80% men, median age 38 (IQR 22) years) rescuers from both organisations.Primary and secondary outcome measures We offered a questionnaire to rescuers, which included Maslach Burnout Inventory, quantifying emotional exhaustion (EX), cynicism (CY) and professional efficacy (PE) along with fatigue, stress and health-related quality of life (HRQL) tools.Results Lower scores of HRQL (Physical Component Score (PCS) beta −0.04 (95% CI −0.06 to −0.02); Mental Component Score beta −0.03 (95% CI −0.05 to −0.01)), higher fatigue (Fatigue Severity Scale (FSS) score beta 0.03 (95% CI 0.03 to 0.04)) and stress (Perceived Stress Score-10 beta 0.04 (95% CI 0.02 to 0.06)) independently predicted greater EX. …”
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Clinical Holistic Medicine: Holistic Pelvic Examination and Holistic Treatment of Infertility by Søren Ventegodt, Mohammed Morad, Joav Merrick

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The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors by Jiajie Tu, Huan Yang, Lei Jiang, Yu Chen, Yu Chen, Zhe Li, Lei Li, Yuanyuan Zhang, Xiaochun Chen, He Chen, Zhiying Yu

“…These estrogen-dependent tumors seriously threaten the health and quality of life in women. Noncoding RNAs (ncRNAs) are defined as RNAs that do not encode proteins, including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), both of which have been reported in estrogen-dependent female reproductive system tumors. …”
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Advanced point-of-care biomarker testing for the diagnosis of cardiovascular diseases by Wenjun Ming, Yidan Zhu, Wenjun Jiang, Jing Zhang, Jinxia Liu, Li Wu, Yuling Qin

“…Cardiovascular disease (CVD) stands as the primary cause of global mortality, necessitating early diagnosis for mitigating death rates and improving quality of life. Conventional CVD diagnostic techniques necessitate the use of bulky hospital instruments for electrocardiogram recording and immunoassay, resulting in time-consuming and inconvenient limitations. …”
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Effects of Self-Care Education on Self-Neglect Among Older Adults by Fereshteh Davoodi, Shahzad Pashaeypoor, Mehrnoosh Partovirad, Farshad Sharifi, Nasrin Nikpeyma

“…Introduction: Self-neglect, a form of abuse, significantly impacts the physical, mental, and social health of older adults, leading to a diminished quality of life and, in severe cases, death. For older adults experiencing self-neglect, attention to self-care is crucial for preventing or managing health issues. …”
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