Tumor-derived exosomal lncRNA-MIR193BHG promotes bone metastasis of breast cancer by targeting the miR-489-3p/DNMT3A signaling axis in osteoclasts by Xiaoya Liu, Rui Ma, Feng Wei, Maihuan Wang, Yiwei Jiang, Peng Zheng, Zhen Cao

“…Despite advances in adjuvant therapies, bone metastasis remains a challenge for patient survival and quality of life. Exosomes, small vesicles capable of mediating intercellular communication, play a crucial role in tumor metastasis. …”
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Salvage transoral laser microsurgery for early local recurrence of glottic squamous cell cancer by Zhimou Cai, Huijun Yue, Lin Chen, Yang Xv, Yun Li, Bingjie Tang, Yu Lin, Wenbin Lei

“…Compared with the OPL group, postsurgical health-related quality of life and quality of voice were significantly better in the TLM group (p < 0.001). …”
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Effects of Breast-Conserving Surgery Combined with Sentinel Lymph Node Biopsy on Breast Cosmetic Appearance and Systemic Stress of Patients with Breast Cancer by Jing Ji, Junfeng Shi, Xia Da, Guozhu Wang, Jin Xu

“…The observation group was significantly superior to the control group in terms of the postoperative quality of life (p < 0.05). After treatment, the levels of plasma procalcitonin (PCT) and tumor necrosis factor-α (TNF-α) in the two groups decreased. …”
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Effects of Different Taping Techniques in Individuals with Myofascial Pain Syndrome with a Trigger Point in the Trapezius Muscle: A Sham-controlled Randomized Study by Kubra KARDES, Pinar VAN DER VEER, Yunus Emre TUTUNEKEN, Hale Nur AYKAC, Esra ARSLAN, Aysenur AKSOY, Yasemin BURAN CIRAK

“…The visual analog scale was used to assess pain, cervical joint range of motion (ROM) with a universal goniometer, grip strength with a hand dynamometer, number of active trigger points by palpation, pressure-pain threshold with an algometer, quality of life with the Nottingham Health Profile and functional level with the Neck Disability index were evaluated before and after treatment. …”
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Cost-effectiveness analysis of durvalumab with chemotherapy and maintenance durvalumab with or without olaparib for advanced endometrial cancer by Jiahao Zhang, Jianying Lei, Caicong You, Wu Fu, Bin Zheng, Hongfu Cai, Maobai Liu, Na Li

“…A Markov model based on DUO-E Phase III trial data simulated disease progression and outcomes. Total costs, quality-adjusted life years (QALYs), and incremental cost-effectiveness ratios (ICER) were evaluated. …”
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Advancements related to probiotics for preventing and treating recurrent respiratory tract infections in children by Yali Zhang, Yali Zhang, Yingying Xu, Yingying Xu, Ling Hu, Ling Hu, Xiaomei Wang

“…Recurrent respiratory tract infections (RRTIs) are a common condition in pediatrics and significantly impact children's quality of life; however, their pathogenesis and contributing factors are not yet fully elucidated. …”
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Development and feasibility of an mHealth intervention for psychoeducational support of Nigerian women diagnosed with breast cancer undergoing chemotherapy: A pilot randomized cont... by Oluwadamilare Akingbade, Ka Yi Hong, Oluwabukola Sharon Ayo, Adetutu Sefinat Alade, Moshood Akinwumi Lawal, Ibironke Elizabeth Somoye, Victoria Adediran, Olamide Sado, Ka Ming Chow

“…Chemotherapy, a common treatment modality for BC, often leads to various physical and psychological side effects, impacting patients' quality of life. Despite the growing use of mobile health (mHealth) interventions to provide psychoeducational support, there is a paucity of evidence regarding their feasibility and acceptability among Nigerian women with BC.…”
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Wearable devices may aid the recognition of fluctuation-related pain in Parkinson's disease-An exploratory, cross-sectional analysis of two prospective observational studies. by Katarina Rukavina, Juliet Staunton, Pavlos Zinzalias, Magdalena Krbot Skoric, Kit Wu, Kirsty Bannister, Alexandra Rizos, K Ray Chaudhuri

“…Fluctuation-related pain (FRP) affects more than one third of people with Parkinson's disease (PwP, PD) and has a harmful effect on health-related quality of life (HRQoL), but often remains under-reported by patients and neglected by clinicians. …”
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Economic Evaluation of a Novel Treatment of Attention-Deficit/Hyperactivity Disorder in US Motor Vehicle Drivers by Jacie T. Cooper, John E. Schneider, Jim Potenziano, David S. Fam

“…When the value of quality-of-life improvement is considered, savings increase over 7-fold. …”
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Oral Complications in Hematopoietic Stem Cell Recipients: The Role of Inflammation by T. M. Haverman, J. E. Raber-Durlacher, W. M. H. Rademacher, S. Vokurka, J. B. Epstein, C. Huisman, M. D. Hazenberg, J. J. de Soet, J. de Lange, F. R. Rozema

“…Oral complications are associated with substantial morbidity and in some cases with increased mortality and may significantly affect quality of life, even many years after HSCT. Inflammatory processes are key in the pathobiology of most oral complications in HSCT recipients. …”
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Influence of symptom burden on social alienation in lung cancer patients receiving chemotherapy: the chain mediating effect of perceived social support and positive psychological c... by Jiahao Wei, Ziye Bai, Mengru Bu, Guining Dang, Xiumei Wu, Jin Zhou

“…Clinical interventions aimed at bolstering PSS and augmenting PPC may potentially alleviate social alienation and enhance the quality of life for patients undergoing chemotherapy for LC.…”
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Robotic Systems for Hand Rehabilitation—Past, Present and Future by Bogdan Gherman, Ionut Zima, Calin Vaida, Paul Tucan, Adrian Pisla, Iosif Birlescu, Jose Machado, Doina Pisla

“…Stroke remains the third leading cause of death worldwide and significantly impacts patients’ hand functionality, making hand rehabilitation crucial for improving quality of life. <b>Methods:</b> A comprehensive literature review was conducted analyzing over 300 papers, and categorizing them based on mechanical design, mobility, and actuation systems. …”
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Immunotherapy as a neoadjuvant preoperative treatment for locally advanced pulmonary sarcomatoid carcinoma: a case report of clinical efficacy by Hanhan Li, Hanhan Li, Ruilian Chen, Wei Guo, Shang Xiang, Shang Xiang, Jiayang Huang, Jiayang Huang, Hanrui Chen

“…At present, the patient maintains a good quality of life, continues with immunotherapy for consolidation and prevention of recurrence, and has reached a survival period of 10 months.ConclusionFor patients with locally advanced PSC who do not have significant genetic mutations, the use of immunotherapy as a first-line neoadjuvant and adjuvant therapy may hold promise for achieving a pCR. …”
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Osteoarthritis of the knee joint and its association with metabolic syndrome: A case control study by Rohini Motwani, Arvind Kumar Bodla, Shravan Kumar Peddamadyam, Mrudula Chandrupatla, Nagesh Cherukuri, Maheshwar Lakkireddy, Gunvanti Rathod, Sai Ram Challa, Chowdavarapu Raghavendra Rao, Abhishek Arora, Srikanth Eppakayala, Arcot Reddy Vamsi Krishna

“…Background: Osteoarthritis of the knee joint (OAK) represents a leading cause of pain, functional limitation, and diminished quality of life, particularly among older adults. The association between metabolic syndrome (MetS) and OAK is of growing interest due to the potential impact of MetS components on joint health. …”
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Social inclusion programming for older adults living in age-friendly cities: a scoping review by Josephine McMurray, Madalena Pamela Liougas, Adriana Fortino, Kari Brozowski

“…Our findings will inform AFC practices and policies by deepening our understanding of how social inclusion can be improved for older adults, including those from under-represented groups, ensuring an equitable approach to enhancing quality of life.…”
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Benefit from regular versus leakage-related exchange of voice prostheses in patients post-laryngectomy considering complication rates and patient satisfaction feedback—a randomized... by Michał Żurek, Małgorzata Czesak, Daniel Majszyk, Anna Rzepakowska

“…ObjectiveThe complications related to voice prosthesis usage substantially affect the physical and social functioning of patients after total laryngectomy, which influences their quality of life. Leakage dysfunction is the most common, causing uncertainty and requiring unscheduled hospital visits. …”
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Safety and performance of oropharyngeal muscle strength training in the treatment of post-stroke dysphagia during oral feeding: protocol for a systematic review and meta-analysis by Xin Wang, Ying Wang, Fenghua Zhou, Minxing Gao, Lingyuan Xu, Heying Wang, Jinan Song, Xiaoqiu Yang

“…Most patients post-stroke are incapable of oral feeding, which often leads to complications such as malnutrition, aspiration pneumonia and dehydration that seriously affect the quality of life of patients. Oropharyngeal muscle strength training is a major method of swallowing training, and recent studies have focused on healthy adults, elderly persons, and patients with head and neck cancer or neurodegenerative diseases; but there have been few studies on such training in patients with post-stroke dysphagia. …”
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Novel Protein-Repellent and Antibacterial Resins and Cements to Inhibit Lesions and Protect Teeth by Li Cao, Junling Wu, Qiang Zhang, Bashayer Baras, Ghalia Bhadila, Yuncong Li, Mary Anne S. Melo, Michael D. Weir, Yuxing Bai, Ning Zhang, Hockin H. K. Xu

“…Orthodontic treatment is increasingly popular as people worldwide seek esthetics and better quality of life. In orthodontic treatment, complex appliances and retainers are placed in the patients’ mouths for at least one year, which often lead to biofilm plaque accumulation. …”
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Cost-Effectiveness of the CNIC-Polypill Strategy Compared With Separate Monocomponents in Secondary Prevention of Cardiovascular and Cerebrovascular Disease in Portugal: The MERCUR... by Carlos Aguiar, Francisco Araujo, Gabriel Rubio-Mercade, David Carcedo, Silvia Paz, Jose María Castellano, Valentín Fuster

“…**Discussion:** The model reflects increments in the number of years patients would live and in quality of life with the CNIC-Polypill. The clinical effectiveness of the CNIC-Polypill strategy initially demonstrated in the NEPTUNO study has been recently corroborated in the SECURE trial. …”
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Artificial Intelligence in Pediatric Epilepsy Detection: Balancing Effectiveness With Ethical Considerations for Welfare by Marina Ramzy Mourid, Hamza Irfan, Malik Olatunde Oduoye

“…It profoundly impacts both developmental progress and quality of life in affected children. With the advent of artificial intelligence (AI), there's a growing interest in leveraging its capabilities to improve the diagnosis and management of pediatric epilepsy. …”
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