Rotigotine Objectively Improves Sleep in Parkinson’s Disease: An Open-Label Pilot Study with Actigraphic Recording by Giovanna Calandra-Buonaura, Pietro Guaraldi, Andrea Doria, Stefano Zanigni, Stefania Nassetti, Valentina Favoni, Sabina Cevoli, Federica Provini, Pietro Cortelli

“…Sleep disturbances represent important predictors of poor quality of life (QoL) in Parkinson’s disease (PD). This open-label pilot study aimed to objectively assess, by means of actigraphic recording, effect of rotigotine on sleep in PD patients with self-reported sleep complaints. 15 PD patients underwent one-week actigraphic recording before (T0) and during (T1) rotigotine treatment, which was titrated to the dose subjectively improving motor symptoms (4–8 mg/24 h). …”
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Comparative study between efficacy of topical tofacitinib 2% ointment versus topical clobetasol propionate 0.05% ointment in hand eczema at a tertiary hospital in central India [ve... by Dr Adarshlata Singh, Drishti Bhatt

“…Background Hand eczema is a prevalent dermatological condition that significantly impacts the quality of life of affected individuals. Topical corticosteroids, such as Clobetasol Propionate, are commonly employed for management, but concerns regarding long-term use and potential side effects necessitate exploration of alternative treatments. …”
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Assist-linked brief intervention to reduce risky pattern of substance use in male workers employed at a tertiary care hospital in India: A randomized controlled trial by Sambhu Prasad, Debasish Basu, Surendra K. Mattoo, B. N Subodh

“…The subjects were compared on ASSIST score, WHO quality-of-life brief version (WHOQOL-BREF) and readiness to change questionnaire (RCQ) at baseline and at 3-month follow up. …”
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Immune cell profiles and predictive modeling in osteoporotic vertebral fractures using XGBoost machine learning algorithms by Yi-Chou Chen, Hui-Chen Su, Shih-Ming Huang, Ching-Hsiao Yu, Jen-Huei Chang, Yi-Lin Chiu

“…Abstract Background Osteoporosis significantly increases the risk of vertebral fractures, particularly among postmenopausal women, decreasing their quality of life. These fractures, often undiagnosed, can lead to severe health consequences and are influenced by bone mineral density and abnormal loads. …”
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Body Image Disturbances Have Impact on the Sexual Problems in Chinese Systemic Lupus Erythematosus Patients by Biyu Shen, Yan He, Haoyang Chen, Chunmei Zhao, Li Zhu, Yingying Gao, Yunli Ren, Xueqing Wang, Jingwei Liu

“…The current study investigated the relationship among disease parameters, quality of life, the psychological status, BID, and sexual problems in Chinese patients with SLE. …”
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Educational Migration in Russian Regions: Statistical Approach by E. A. Pitukhin, O. A. Zyateva, L. V. Shchegoleva, V. E. Sokolov

“…The clustering of 83 regions according to the space of selected characteristics resulted in five clusters with different values of the indicator of educational migration and different values of indicators of the quality of life. Three territorially different educational centers of gravity were identified: “Metropolitan”, “Southern” and “Siberian”, which include 27 regions of Russia from the two best clusters by the indicator of educational migration. …”
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Exercise and exerkines: Mechanisms and roles in anti-aging and disease prevention by Xuan Lu, Ying Chen, Yue Shi, Yi Shi, Xianbin Su, Peijie Chen, Die Wu, Hui Shi

“…As our understanding deepens, it may pave the way for personalized interventions leveraging physical activity to enhance healthspan and improve quality of life.…”
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Frequency of Diplopia in Zygomatic Complex Fractures—A Cross-Sectional Descriptive Study by Maria Shabbir, Ruqaya Shah, Muhtada Ahmad, Rakhi Issrani, Zafar Khan, Salah Nazal Alotha, Basant Mousa Alsiyat, Mohammed Saad Alqarni, Ahmed Saleh Albalawi, Namdeo Prabhu, Mohammad Khursheed Alam, Zahid Qayyum

“…Thus, forming a strategy to properly diagnose and treat it and to prevent persistent morbidity to improve patient’s quality of life is recommended.…”
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A Systematic Literature Review and Bucher Indirect Comparison: Tildrakizumab versus Guselkumab by Kristian Garn Du Jardin, Pepi Hurtado Lopez, Mette Lange, Rachael McCool, Silvia Maeso Naval, Sandra Quickert

“…**Background:** Psoriasis is a chronic inflammatory skin condition that impacts quality of life and requires long-term treatment and effective symptom management. …”
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To Assess Caregiver Burden of Patients with Dementia: Its Sociodemographic and Clinical Correlates by Vijay Raghuwanshi, Pali Rastogi, Vijay Niranjan, Prashant Maravi, Virendra S. Pal

“…The morbidities associated with dementia accounts for the poor quality of life. Equally affected are caregivers of these patients. …”
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The Influence of the Social Support on Symptoms of Anxiety and Depression among Patients with Silicosis by Bing Han, Bo Yan, Jian Zhang, Na Zhao, Jinkai Sun, Chao Li, Xibing Lei, Hongbo Liu, Jie Chen

“…The study aimed to examine the influence of the social support on symptoms of anxiety and depression among patients with silicosis and provide the scientific basis to further alleviate anxiety and depression and to monitor their whole quality of life. We investigated 324 inpatients with silicosis between April 2011 and September 2011. …”
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Reliability, Responsiveness, and Validity of the Visual Analog Fatigue Scale to Measure Exertion Fatigue in People with Chronic Stroke: A Preliminary Study by Benjamin Y. Tseng, Byron J. Gajewski, Patricia M. Kluding

“…Post-Stroke Fatigue (PSF) is a prevalent yet commonly neglected issue that impacts daily functions and quality of life in people post-stroke. To date no studies have attempted to validate a clinically-feasible and reliable instrument to quantify PSF. …”
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Examining the Impact of Certificate of Need Laws on the Utilization and Reimbursement of Cataract Surgeries Among Medicare Beneficiaries by Alvina Liang, Jennifer L. Lindsey

“…**Background:** Cataract surgery is an effective and commonly utilized procedure and can significantly improve quality of life and restore economic productivity. Certificate of need (CON) laws aim to regulate healthcare facility expansion and equipment acquisition to curtail costs, enhance quality, and ensure equitable access to care. …”
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Human Development from Concept "Soft Skills" Communication by Emilawati Binti Othman, Masfizaizan Binti Manaf

“…In this regard, human resource management dominates the careful planning and maximizes energy to be applied towards achieving a systematic and efficient communication skills and expertise in order to improve the quality of life and to protect the well-being of mankind. …”
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MRgFUS subthalamotomy in Parkinson’s disease: an approach aimed at minimizing Lesion Volume by Marina Campins-Romeu, Rebeca Conde-Sardón, Isabel Sastre-Bataller, Carlos Morata-Martínez, Mireya Losada-López, José Luís León-Guijarro, Luis Raga-Rodríguez, Julia Pérez-García, Antonio Gutiérrez-Martín, Andrés M. Lozano, Raquel Baviera-Muñoz, Irene Martínez-Torres

“…Results indicated significant motor improvements, with over 50% reduction in tremor, rigidity, and bradykinesia, while balance and gait remained stable. Quality of life also improved. Side effects were generally mild and transient, though some patients experienced involuntary movements, managed through medication adjustments. …”
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Indicators of  sustainable development of  the economic ecosystem of  the territory by E. V. Popov, I. P. Chelak, S. A. Kavetskiy

“…The territory is considered as an ecosystem, its main elements are highlighted which interact with each other and on which the sustainable development of the region, its competitiveness and the quality of life of residents directly depend. The paper presents the indicators, and on their basis the assessment of the level of the sustainable development of the territories is conducted. …”
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Cerebral Blood Flow in Orthostatic Intolerance by Muhammad Shahzeb Khan, Amanda J. Miller, Arooba Ejaz, Jeroen Molinger, Parag Goyal, David B. MacLeod, Ashley Swavely, Elyse Wilson, Meghan Pergola, Harikrishna Tandri, Camille Frazier Mills, Satish R Raj, Marat Fudim

“…Many forms of orthostatic intolerance (OI) involve impaired regulation of CBF in the upright posture, which results in disabling symptoms that decrease quality of life. Because CBF is not easy to measure, rises in heart rate or drops in blood pressure are used as proxies for abnormal CBF. …”
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Impacts of the COVID-19 pandemic on HIV care and treatment services among adolescents attending a tertiary hospital in Dar es Salaam, Tanzania: a qualitative study by Agricola Joachim, Dorkasi L Mwakawanga, Lilian Nkinda, Eva Kidabulo

“…Loss of family income, food insecurity and limited socialisation posed threat to adolescent’s mental health and overall quality of life.Conclusion Our findings underscore the impacts of COVID-19 and its immediate responses that significantly affected adolescent HIV care and treatment services. …”
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Positive and negative aspects of remote learning during the COVID-19 pandemic in the view of Brazilian university students who received university assistance by Vera Lucia Messias Fialho Capellini, Jie Zhang, Luciana Marolla Garcia, Marcelo Setsuo Hashimoto, Eduardo Pimentel da Rocha

“…These positive factors may have contributed to reducing stress caused by COVID-19, increasing student retention and course completion rate, and improving student’s quality of life. On the contrary, participants reported negative aspects, such as lack of internet access, excess of activities, concerns about teaching quality, inadequate study environments, family-related problems, and insufficient materials and technology tools.DiscussionDespite the fears and insecurities, the pandemic brought to the students, our study found that the help offered by the university to students proved to be beneficial, positively impacting student development and retention. …”
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The impact of depression and anxiety disorders on postoperative outcomes for patients having total hip or knee arthroplasty: Protocol of a meta-analytic study from cohort studies. by Liang Lin, Qing Zhang, Min Xu, Zhihong Xiao, Guosong Xu, Zubing Mei

“…The findings will guide clinicians in recognizing and managing mental health issues to optimize postoperative recovery and ultimately improve patient satisfaction and quality of life.<h4>Study registration</h4>Study registration: CRD42024500008.…”
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