Chronic Obstructive Pulmonary Disease Patients With Community‐Acquired Pneumonia on Inhaled Corticosteroid Therapy: A Comprehensive Analysis of Risk Factors, Disease Burden, and Pr... by Muhammad Muneeb Hassan, Sheikh Muhammad Sikandar, Farrukh Jamal, Muhammad Ameeq, Alpha Kargbo

“…ABSTRACT Background Chronic obstructive pulmonary disease (COPD) patients commonly exhibit significant morbidity and experience a diminished quality of life. Since there has been no prior research on pneumonia in our study population, we carried out this study to learn more about the situation. …”
Get full text

It Takes a Village: The Importance of Neuropsychological Findings in a Collaborative Approach for a Patient with Congenital Central Hypoventilation Syndrome and Specific Phobia by Sarah Hamill Skoch, Bo Fu, Amanda L. Stein, Samuel P. Greenstein

“…The collaborative care we provided offers insights which may direct future interventions for patients with CCHS and improve their quality of life. Our case adds support to the recommendation that patients with CCHS and impaired psychosocial functioning should receive neuropsychological testing to best direct treatment.…”
Get full text

Relation between Headache and Mastication Muscle Tone in Adolescents by Ewa Wozniak, Jolanta E. Loster, Aneta Wieczorek

“…Headache is a common problem in the population, which decreases the quality of life and makes everyday functioning difficult. …”
Get full text

Prosthetic rehabilitation, failures and their causes by Yulemy Portal García, Anabel Zurbano Cobas, María Gabriela Pérez Cuevas, Lorena Camacho Guerrero, Lisbet Pineda Bombino, Dairon Aguilar Valdez

“…Introduction: The identification of factors that contribute to the failure of prosthetic rehabilitations is crucial to improve the clinical results and quality of life of patients. Objective: To describe the causes of prosthetic rehabilitation failures in patients treated in the Prosthetics Service at Arnaldo Milián Castro Hospital from January 2019 to March 2020. …”
Get full text

Efficacy of High-Voltage Pulsed Radiofrequency in Zoster-Associated Pain: A Meta-Analysis and Systematic Review by Yinghao Song, Ziheng Yu, Jingjing Guan, Haisheng Wu, Jinglang Zhang, Liu Qiaoling, Min Yuan, Xinzhi Cheng, Bingyu Ling

“…H-PRF is an effective and safe treatment method that has better effects in relieving pain and improving the quality of life and physical and mental health. Although H-PRF provides pain relief rates comparable to those of the control group in the early stages, it remains the preferred and alternative treatment for relieving herpes zoster-related pain.…”
Get full text

Like a Wave in Its Variable Shape, Breadth, and Depth: A Qualitative Interview Study of Experiences of Daytime Sleepiness in People with Parkinson’s Disease by Arja Höglund, Peter Hagell, Ulrika Östlund, Sten Fredrikson, Christina Sandlund

“…Daytime sleepiness is a common nonmotor symptom in Parkinson’s disease (PD) which is associated with decreased quality of life and perceived health. However, experiences of daytime sleepiness in people with PD have not been explored. …”
Get full text

Comprehensive Analysis of microRNA Methylation Profiles and Determination of Their Functional Significance in Colorectal Cancer: A Study Protocol by Nurul Syakima Ab Mutalib, Imilia Ismail, Muhammad Redha Abdullah Zawawi, Nadiah Abu, Siti Aishah Sulaiman, Loh Teng-Hern Tan, Learn-Han Lee

“…Effective CRC diagnosis ensures timely and appropriate treatment for patients, thereby improving their quality of life. The insights gained from this study could be applied to individualized health diagnostics, disease prognostication, and treatment monitoring. …”
Get full text

An Enhanced Deep Neural Network for Predicting Workplace Absenteeism by Syed Atif Ali Shah, Irfan Uddin, Furqan Aziz, Shafiq Ahmad, Mahmoud Ahmad Al-Khasawneh, Mohamed Sharaf

“…This paper is a first study of its kind to analyze the patterns of absenteeism in employees using deep learning algorithms and helps the organization to further improve the quality of life of employees and hence reduce absenteeism.…”
Get full text

Qualitative study exploring the views and perceptions of parents/carers of young children with CF regarding the introduction of CFTR modulator therapy (The REVEAL study; PaRents pE... by Kevin W Southern, Sioned Haf Davies, Faye Wade, Heather Fogg, Adam Walsh

“…Recently, a new medication, elexacaftor/tezacaftor/ivacaftor (ETI), has become available to some people with CF, which has had a significant impact on the quality of life of older children and adults. This medication will soon be available for children ages 2–5 in the UK. …”
Get full text

Autologous Bone Marrow-Derived Chondrocytes for Patients with Knee Osteoarthritis: A Randomized Controlled Trial by Mir Sadat-Ali, Abdallah S. AlOmran, Sulaiman A. AlMousa, Hasan N. AlSayed, Khalid W. AlTabash, Mohammed Q. Azam, Tarek M. Hegazi, Sadananda Acharya

“…The aim of this study was to compare the effect of autologous bone marrow-derived chondrocytes (ABMDCs) with pharmacological management of osteoarthritis of knee (OAK) and assess the benefit of the two in the improvement of pain relief, functional betterment, and quality of life (QOL). Patients and Methods. A prospective, randomized study was undertaken in patients with OAK grades II and III of Kellgren–Lawrence grading (KLG) in two groups. …”
Get full text

Study on Influencing Factors and Countermeasures of Elderly Nursing Services in the Elderly by Shuo Liu, Li Chen, Dandan Li, Qianqian Yang, Fangfang Liu, Yanli Cheng

“…Therefore, relevant departments should formulate corresponding measures to improve the quality of life of the elderly.…”
Get full text

‘I really feel like I am ageing early’: an interpretative phenomenological analysis of the lived experience of young adults with life-limiting conditions (YALLC) by Poh Heng Chong, Xiangyi Chen, Zhi Zheng Yeo, Celene Ting, Ya Nee Poh, Qishun Raymond Ang

“…Contextual understanding and identified gaps from this study will guide affirmative strategies to improve quality of life among a growing cohort.…”
Get full text

A data-driven cluster analysis to explore cognitive reserve and modifiable risk factors in early phases of cognitive decline by Sara Bernini, Alice Valcarenghi, Elena Ballante, Federico Fassio, Marta Picascia, Elena Cavallini, Matteo Cotta Ramusino, Alfredo Costa, Tomaso Vecchi, Cristina Tassorelli, Sara Bottiroli

“…Specifically, Cluster 1 exhibited advantages in: (1) sociodemographic (education, technological skills, and occupation), (2) cognitive (global cognitive functioning, executive functioning, and working memory), and (3) mental health (mood state and quality of life) characteristics. Such a finding is representative of a more positive individual wellbeing for people who adopt protective behaviours. …”
Get full text

Risk Factors Analysis of Cutaneous Adverse Drug Reactions Caused by Targeted Therapy and Immunotherapy Drugs for Oncology and Establishment of a Prediction Model by Zimin Zhang, Mingyang Zhu, Weiwei Jiang

“…These findings have important implications for optimizing therapeutic efficacy and maintaining the quality of life of patients from the perspective of managing cutaneous adverse drug reactions. …”
Get full text

Cellular Mechanisms of Multiple Myeloma Bone Disease by Angela Oranger, Claudia Carbone, Maddalena Izzo, Maria Grano

“…These skeletal complications have not only a negative impact on quality of life but also a possible effect in overall survival. …”
Get full text

CIRCADIAN RHYTHM AND INDICATORS OF SYSTEMIC INFLAMMATION IN PATIENTS WITH PSORIASIS AND CONCOMITANT ALIMENTARY OBESITY by Ya.O. Yemchenko, K.Ye. Ishcheikin, I.P. Kaidashev

“…The recent increase in the incidence of comorbid psoriasis and obesity leads to severe, atypical, disabling, and treatment-resistant forms of dermatosis, which significantly impair the quality of life of patients, reduce the efficiency and social activity of patients, thus acquiring not only a medical but also a social significance. …”
Get full text

Clinical Utility of Zuranolone for Postpartum Depression: A Narrative Review by Giannopoulos A, Singh J, Deligiannidis KM

“…Secondary analyses demonstrated that zuranolone improves comorbid symptoms of anxiety and insomnia and some measures of health-related quality of life. Zuranolone relevant infant dose lactation data suggest that its use is compatible with breastfeeding, though future research is needed to measure potential adverse effects on the breastfed infant. …”
Get full text

The Helplessness Dimension of Pain Catastrophizing Mediates the Relation between PTSD Symptoms and Pain Rehabilitation Measures by Matthew Schumann, Julia Craner, Elizabeth Kacel, Eleshia Morrison, Keith Gascho, Judy Gebhard, Wesley Gilliam

“…The patients completed measures of pain severity, pain interference, pain catastrophizing, depressive symptoms, quality of life (QOL), and PTSD symptoms at pretreatment. …”
Get full text

Mother’s Characteristics and Socioeconomic Status as Possible Risk Factors for Children’s Caries in Jordan by Omar Al-Rashdan, Zaid AlZoubi, Mahmoud Ibrahimi, Amal Al-khraisha, Nabeel Almajali

“…Clinical oral health status of children affects their health-related quality of life. A major determinant of oral health is early childhood caries, which possesses a negative effect. …”
Get full text

Economic Evaluation of Fidaxomicin for the Treatment of Clostridium Difficile Infection (C. difficile-associated diarrhoea) in Ireland by Anke van Engen, Montserrat Casamayor, Fidelma Loftus, Martin Coen, Andy Garnham, Maureen Watt, Larry Lacey

“…**Results:** In the base case, fidaxomicin was dominant to current standard-of-care therapy, with cost savings of €2,904 and incremental quality-adjusted life year (QALY) gain of 0.031. The main drivers of costeffectiveness were recurrence rates and cost of hospitalization. …”
Get full text