Induced Hypothermia Does Not Harm Hemodynamics after Polytrauma: A Porcine Model by Matthias Weuster, Philipp Mommsen, Roman Pfeifer, Juliane Mohr, Steffen Ruchholtz, Sascha Flohé, Matthias Fröhlich, Claudia Keibl, Andreas Seekamp, Martijn van Griensven, Ingo Witte

“…Mean arterial blood pressure, central venous pressure, pulmonary arterial pressure, and wedge pressure showed no significant differences comparing normothermic trauma and hypothermic trauma pigs during hypothermia. …”
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Dietary Flaxseed Oil Protects against Bleomycin-Induced Pulmonary Fibrosis in Rats by Joshua Lawrenz, Betty Herndon, Afrin Kamal, Aaron Mehrer, Daniel C. Dim, Cletus Baidoo, David Gasper, Jonathan Nitz, Agostino Molteni, Richard C. Baybutt

“…At days 7 and 21, bleomycin produced a reduction in pulmonary arterial lumen patency (𝑃=0.01), but not in rats that were treated with flaxseed oil. …”
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Effects of Sildenafil and Vitamin E on Paraquat-Induced Pulmonary Fibrosis in Rats by Fouziyeh Siahpour, Hosein Sadeghi, Esmaeel Panahi kokhdan, Mohammad Khoshnoud

“…Drugs like sildenafil, which inhibits phosphodiesterase enzymes, are used to treat pulmonary arterial hypertension. Antioxidants such as vitamin E can restore the oxidant-antioxidant balance. …”
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Echocardiography in Confirmed and Highly Suspected Symptomatic COVID-19 Patients and Its Impact on Treatment Change by Nadia Benyounes, Clélie Van Der Vynckt, Séverine Tibi, Alexandra Iglesias, Laurence Salomon, Olivier Gout, Thierry Tibi

“…On echocardiography, higher systolic pulmonary arterial pressure and documented cardiac thrombi were associated with treatment changes in these patients. …”
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Investigation of possible predictive factors, clinical characteristics, and treatment in vascular Behçet's disease: real-life data from a single center by Abdulvahap Kahveci, Zeycan Kübra Cevval

“…The most common subtype of vascular Behçet's is deep vein thrombosis (18; 64.2%), followed by superficial thrombophlebitis (5; 17.8%), neurovascular involvement (5; 17.8%), cardio-aortic (2; 7.1%) and pulmonary arterial (2; 7.1%). Azathioprine, glucocorticoid, and cyclophosphamide are the most preferred immunosuppressives in vasculo-Behçet's. …”
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Predictive Value of Novel Inflammation-Based Biomarkers for Pulmonary Hypertension in the Acute Exacerbation of Chronic Obstructive Pulmonary Disease by Huanhuan Zuo, Xiaochen Xie, Jiahuan Peng, Lixin Wang, Rong Zhu

“…The blood biomarker levels were positively correlated with NT-proBNP levels, while they had no significant correlation with the estimated pulmonary arterial systolic pressure (PASP) other than PLR. …”
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Exhaled Nitric Oxide in Systemic Sclerosis Lung Disease by Natalie K. Kozij, John T. Granton, Philip E. Silkoff, John Thenganatt, Shobha Chakravorty, Sindhu R. Johnson

“…Exhaled nitric oxide (eNO) is a potential biomarker to distinguish systemic sclerosis (SSc) associated pulmonary arterial hypertension (PAH) and interstitial lung disease (ILD). …”
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Postoperative Pulmonary Hemodynamics and Systemic Inflammatory Response in Pediatric Patients Undergoing Surgery for Congenital Heart Defects by Maria Francilene S. Souza, Juliano G. Penha, Nair Y. Maeda, Filomena R. B. G. Galas, Kelly C. O. Abud, Eloisa S. Carvalho, Ana Maria Thomaz, Claudia R. P. Castro, Juliana Pereira, Antonio Augusto Lopes

“…We prospectively studied 40 patients aged 11 (8–17) months (median with interquartile range) with a preoperative mean pulmonary arterial pressure of 48 (34–54) mmHg who were considered to be at risk for postoperative pulmonary hypertension. …”
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Comparative Efficacy and Safety of Targeted Therapies for Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review and Network Meta-Analysis by Yusi Chen, Fang Li, Jun Luo, Jingyuan Chen, Peng Luo, Jiang Li

“…There is significant controversy relating to whether chronic thromboembolic pulmonary hypertension (CTEPH) can be treated with pulmonary arterial hypertension- (PAH-) targeted therapies and which therapy is the optimal choice for patients. …”
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Ghrelin Protects Lipopolysaccharide-Induced Acute Lung Injury Rats against Pulmonary Vascular Dysfunction by Inhibiting Inflammation by Guang Li, Chen-Liang Zhou, Wen-Fang Xia, Di Zhang, Hui-Qing Lin

“…Four hours after establishing the ALI rat model, the mean pulmonary arterial pressure (mPAP), mean right ventricular systolic pressure (RVSP), levels of proinflammatory cytokines tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) in the bronchoalveolar lavage fluid (BALF), BALF cell count, wet-to-dry (W/D) lung weight ratios, and myeloperoxidase (MPO) activity in lung tissue for all four groups (ghrelin, ghrelin + ALI, saline, and saline + ALI) were measured. …”
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Mechanical Thrombectomy System for the Treatment of Intermediate-Risk Acute Pulmonary Embolism: The CLEAR Study by Wenguang Zhang, Tao Hu, Song Ding, Zhouming Wang, Tao Zhang, Hongyao Hu, Xin Fang, Honggang Pang, Mingjin Guo, Bo Yu, Hui Zhuang, Nuofu Zhang, Baoshi Han, Qiguang Wang, Mingzhi Cai, Kuan Wang, Pingfan Guo, Bin Xu, Peiliang Fang, Shengxian Tu, Yi Jiang, Hongyu Shi, Zhenwen Yang, Xinwei Han, Hongyan Tian, Jun Pu, Xiaoming Zhang

“…The secondary efficacy endpoint was the systolic pulmonary arterial pressure (PAP) change from pre- to postprocedure. …”
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Prevalence of pulmonary hypertension and associated factors among rheumatic heart disease patients in Ethiopia by Asmamaw Gedefaw, Yihealem Yabebal Ayele, Gebeyaw Wudie, Abiyot Tefera, Agerye Kassa Yirdaw, Tadele Demilew

“…Results The mean systolic pulmonary arterial pressure (sPAP) of the participants was 50.2 mmHg [SD ± 25.0 mmHg]. …”
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Cardiovascular Development and the Colonizing Cardiac Neural Crest Lineage by Paige Snider, Michael Olaopa, Anthony B. Firulli, Simon J. Conway

“…Once the migratory cardiac neural crest subpopulation finally reaches the heart, they have traditionally been thought to participate in septation of the common outflow tract into separate aortic and pulmonary arteries. However, several studies have suggested these colonizing neural crest cells may also play additional unexpected roles during cardiovascular development and may even contribute to a crest-derived stem cell population. …”
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COVID-19 Viral Pneumonia Complicated with Acute Pulmonary Embolism: A Descriptive Study by Hoda Salah Darwish, Mohamed Yasser Habash, Waleed Yasser Habash

“…We suggest that whenever a CT evaluation of the parenchymal involvement of COVID-19 pneumonia is performed, a simultaneous evaluation of the pulmonary arteries is also essential in order to identify early signs of associated pulmonary embolism.…”
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Relationship Between RNF213 p.R4810K and Echocardiographic Findings in Patients with Cerebrovascular Diseases: A Multicenter Prospective Cohort Study by Kotaro Noda, Yorito Hattori, Tatsuya Nishii, Hiroki Horinouchi, Yuriko Nakaoku, Soshiro Ogata, Yasunobu Inagaki, Ryotaro Asano, Takeshi Yoshimoto, Kunihiro Nishimura, Takeshi Ogo, Yoshikazu Nakaoka, Masafumi Ihara

“…Conclusions A longer right ventricular outflow tract acceleration time may reflect an increased pulmonary vascular bed induced by abnormal vascular collateral networks and dilation of capillary vessels in peripheral pulmonary arteries in the preclinical stage of RNF213‐related pulmonary hypertension. …”
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