Pharmacodynamic characteristics and influencing factors of tapentadol for chronic pain relief under dose titration by Liang Xin, Haoxiang Zhu, Haoxiang Zhu, Suping Niu, Xie Han, Hongxian Pang, Jiangfan Li, Ye Hu, Xuhong Wang, Lujin Li, Lujin Li, Yi Fang

“…Furthermore, studies published after 2014 and placebo-controlled trials showed a slower rate of NRS reduction, indicating a more cautious approach to tapentadol dosing titration post the U.S. opioid crisis and in placebo-controlled contexts. …”
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Histological staining of tick bite skin biopsies for spirochetes and Powassan virus RNA by Jihane Oufattole, Anne Piantadosi, Sam R. Telford, Alvaro C. Laga, Isaac H. Solomon

“…Although limited, our data suggest a poor correlation between ECM and the detection of spirochetes, findings in concordance with the published literature. Similarly, the absence of detectable POWV RNA in any of the tested skin biopsies or patient-derived ticks, including one laboratory confirmed case, suggest the limited utility of POWV ISH for clinical use without further analysis with a larger sample size.IMPORTANCETick-borne infections, including Lyme and Powassan encephalitis, cause significant morbidity and mortality and are challenging to diagnose and study in humans. …”
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Methodological challenges using routine clinical care data for real-world evidence: a rapid review utilizing a systematic literature search and focus group discussion by Michelle Pfaffenlehner, Max Behrens, Daniela Zöller, Kathrin Ungethüm, Kai Günther, Viktoria Rücker, Jens-Peter Reese, Peter Heuschmann, Miriam Kesselmeier, Flavia Remo, André Scherag, Harald Binder, Nadine Binder, for the EVA4MII project

“…Methods We conducted a literature search on routine data studies in four high-impact journals based on the Journal Citation Reports (JCR) category “Medicine, General & Internal” as of 2022 and three oncology journals, covering articles published from January 2018 to October 2023. Articles were screened and categorized into three scenarios based on their potential to provide meaningful RWE: (1) Burden of Disease, (2) Safety and Risk Group Analysis, and (3) Treatment Comparison. …”
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An Insurance Value Modeling Approach That Captures the Wider Value of a Novel Antimicrobial to Health Systems, Patients, and the Population by Mei S. Chan, Richard Holloway, Robert King, Rosie Polya, Rebecca Sloan, Jack C. Kowalik, Tom Ashfield, Luke S.P. Moore, Thomas Porter, Jonathan Pearson-Stuttard

“…Components of this insurance value match previously published estimates of operational costs and mortality impacts. …”
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Machine Learning in the Management of Patients Undergoing Catheter Ablation for Atrial Fibrillation: Scoping Review by Aijing Luo, Wei Chen, Hongtao Zhu, Wenzhao Xie, Xi Chen, Zhenjiang Liu, Zirui Xin

“…MethodsAdhering to the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines, relevant studies published up to October 7, 2023, were searched from PubMed, Web of Science, Embase, the Cochrane Library, and ScienceDirect. …”
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Efficacy and safety of Janus kinase inhibitors in the treatment of psoriasis and psoriatic arthritis: An analysis of evidence from 2014 to 2022 by Jiao Wang, Tian Ma, Xiaoying Sun, Liu Liu, Seokgyeong Hong, Huijung Cha, Miao Zhang, Jiale Chen, Naixuan Lin, Bin Li, Xin Li

“…Methods: Randomized controlled studies (RCTs) assessing JAK inhibitors to treat PSO or PsA published before September 1, 2022, were searched in the PubMed, Embase, and Cochrane Library databases. …”
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Influences of school climate on emotional health and academic achievement of school-going adolescents in India: a systematic review by Jayalaxmi Kaniyagundi Podiya, Janardhana Navaneetham, Poornima Bhola

“…A systematic literature search was conducted across multiple databases, such as PsycINFO, EBSCO Host (Psychology and behavioral sciences collection), PubMed, ERIC, Web of Science, ProQuest Dissertations & Theses Global: The Humanities and Social Sciences Collection, Shodhganga, Cochrane Library, and Google Scholar which are recognized sources of high-quality publications. It covered published as well as unpublished research studies, including peer-reviewed journals and gray literature, such as reports of programs on the impact of the school climate on the emotional health and academic achievement of adolescents between January 2000 and December 2023. …”
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Cost Effectiveness of Insulin Glargine versus Neutral Protamin Hagedorn Insulin in the Treatment of Type 2 Diabetes Patients in Turkey by Ilhan Satman, Hayley Bennett, Candeger Yilmaz, Sazi Imamoglu, Goksun Ayvaz, Abdurrahman Comlekci, Demet Ozkaya, Toros Sahin

“…**Methods:** A previously published discrete event simulation model of T2DM progression was utilised to characterise the cost-effectiveness of insulin glargine in a Turkish population given the benefits observed in clinical practice. …”
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A prospective model of the potential clinical and economic impact of cervical cancer screening supported by a mobile phone app. by Fredrick Chite Asirwa, Brian W Bresnahan, Faith Yego, Dana Duncan, James K Karichu, Louis P Garrison

“…The model is structured to simulate a three-visit pathway for HPV-based screening used in a clinical trial of the app and based on epidemiological data, clinical guideline-based workflow, and patient-based behavioral pathways. Published literature, expert elicitation, and time-and-motion observations were used to estimate clinical data, care pathways, and visit-related costs. …”
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Parkinson’s disease and other movement disorders in the context of the SARS-COV-2 pandemic by R. Kaladytė Lokominienė

“…International Parkinson Disease and Movement Disorders Society has published recommendations and priorities for patients with Parkinson’s disease and other movement disorders during the COVID-19 pandemic which state that all measures of social distancing currently in place for the general population almost globally must be strictly and carefully practiced, direct consultations must be held in exceptional cases (e.g., for adjusting or checking deep brain stimulation programming, battery failure, levodopa duodenal pump treatments, botulinum toxin therapy), and patients should be encouraged to use sports equipment available at home and /or play virtual reality games. …”
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A Review on Blockchain Applications in Operational Technology for Food and Agriculture Critical Infrastructure by Chengliang Zheng, Xiangzhen Peng, Ziyue Wang, Tianyu Ma, Jiajia Lu, Leiyang Chen, Liang Dong, Long Wang, Xiaohui Cui, Zhidong Shen

“…Otoum Safa stands out as the author with the highest number of published articles, totaling four. Keywords such as “blockchain”, “internet of things”, “smart contract”, “security”, and “critical infrastructure” appear with significant frequency. …”
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The Lost Gambit: The Third War between Israel and Egypt, its Causes and Lessons by Alek D. Epstein

“…Dozens of books and hundreds of scientific articles on this war have been published. The current research demonstrates the central role of Egyptian leaders in the onset of the war which nobody sought for. …”
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Interfacial and mass transport phenomena in the tri-ethylene glycol-methane system at process conditions of natural gas dehydration by Stanley Ibeh, Philip Jaeger

“…To the best of our knowledge, there is no such comprehensive work on the properties of fluid mixtures relevant in gas dehydration processes published up to date.…”
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Implementing Namaste Care in nursing care homes for people with advanced dementia: a systematically constructed review with framework synthesis by Serena Salvi, Nancy Preston, Nicola Cornally, Catherine Walshe, on behalf of the In-Touch Consortium

“…Data sources Comprehensive searches were conducted in Medline, CINAHL, and PsycINFO databases for studies published between 2018 and 2024. Search concepts included “Namaste Care,” “advanced dementia,” and related terms. …”
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Transmission Failure Prediction Using AI and Structural Modeling Informed by Distribution Outages by Sita Nyame, William O. Taylor, William Hughes, Mingguo Hong, Marika Koukoula, Feifei Yang, Aaron Spaulding, Xiaochuan Luo, Slava Maslennikov, Diego Cerrai

“…In the current version of the model, we substantially reduced the overestimation in the sum of predicted values of transmission line probability of failure that was present in the previously published model by a factor of 10. This has led to a reduction of model bias from 3352% to 14.46–15.43%. …”
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Pica practices, anemia, and oral health outcomes: a systemic review by Brenda A. Z. Abu, Abigail Morrissey, Yan Wu, Daniel A. Castillo, Rachel Becker, TongTong Wu, Kevin Fiscella, Steven Gill, Jin Xiao

“…Results From 4,159 searched articles, 89 met the inclusion criteria. Studies were published between 1959 and 2022 from 33 countries. …”
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Examining the mental health of siblings of children with a mental disorder: A scoping review protocol. by John E Krzeczkowski, Terrance J Wade, Brendan F Andrade, Dillon Browne, Busra Yalcinoz-Ucan, Negin A Riazi, Elizabeth Yates, Andrea Tagalakis, Karen A Patte

“…We will search peer-review and grey literature published between 2011 and 2022 from OVID MEDLINE, OVID EMBASE, CINAHL Complete, Proquest Nursing and Allied Health, PsycINFO (via APA platform), Proquest Sociology Collection and Web of Science Core Collection and Proquest Theses and Dissertations. …”
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Fifty years of evidence on perinatal experience among refugee and asylum-seeking women in Organization for Economic Co-operation and Development (OECD) countries: A scoping review. by Marwa Ramadan, Hani Rukh-E-Qamar, Seungmi Yang, Zoua M Vang

“…., smoking), or were published in a language other than English. The final list of articles included 82 unique studies.…”
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The implementation and impact of non-invasive prenatal testing (NIPT) for Down's syndrome into antenatal screening programmes: A systematic review and meta-analysis. by Elinor Sebire, Chithramali Hasanthika Rodrigo, Sohinee Bhattacharya, Mairead Black, Rachael Wood, Rute Vieira

“…<h4>Methods and findings</h4>The study protocol was published in PROSPERO (CRD42022306167). We systematically searched MEDLINE, CINAHL, Scopus, and Embase for population-based studies, government guidelines, and Public Health documents from 2010 onwards. …”
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Patient-reported outcomes for diabetes and hypertension care in low- and middle-income countries: A scoping review. by Sarah Masyuko, Carrie J Ngongo, Carole Smith, Rachel Nugent

“…<h4>Methods</h4>We searched PubMed, EMBASE, and ClinicalTrials.gov for English-language studies published between August 2009 and August 2019 that measured at least one PROM related to diabetes or hypertension in LMICs. …”
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