The relationship between walking speed and changes in cardiovascular risk factors during a 12-day walking tour to Santiago de Compostela: a cohort study by Frank L J Visseren, Yolanda van der Graaf, Wilko Spiering, Remy H H Bemelmans, Paulus P Blommaert, Annemarie M J Wassink, Blai Coll

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Effectiveness and safety of metformin in 51 675 patients with type 2 diabetes and different levels of renal function: a cohort study from the Swedish National Diabetes Register by Katarina Eeg-Olofsson, Soffia Gudbjörnsdottir, Ann-Marie Svensson, Björn Eliasson, Linus Schioler, Björn Zethelius, Nils Ekström, Jan Cederholm, Junmei Miao Jonasson

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High-altitude hypoxia aggravated neurological deficits in mice induced by traumatic brain injury via BACH1 mediating astrocytic ferroptosis by Peng Zou, Tianjing Li, Zixuan Cao, Erwan Yang, Mingdong Bao, Haofuzi Zhang, Zhuoyuan Zhang, Dan Liu, Min Zhang, Xiangyu Gao, Junmiao Ge, Xiaofan Jiang, Zhicheng Tian, Peng Luo

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Baryon Pasting the Uchuu Light-cone Simulation by Erwin T. Lau, Daisuke Nagai, Arya Farahi, Tomoaki Ishiyama, Hironao Miyatake, Ken Osato, Masato Shirasaki

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Tackling the Problem of Distributional Shifts: Correcting Misspecified, High-dimensional Data-driven Priors for Inverse Problems by Gabriel Missael Barco, Alexandre Adam, Connor Stone, Yashar Hezaveh, Laurence Perreault-Levasseur

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Validation of insurance claims data on aetiology, surgical type and prosthesis for isolated valve surgery: a retrospective observational surgery by Shao-Wei Chen, Victor Chien-Chia Wu, Pao-Hsien Chu, An-Hsun Chou, Chun-Yu Chen, Feng-Cheng Chang, Yi‐Hsin Chan, Chia-Pin Lin, Yu-Ting Cheng, Bo-Cheng Hou, Jo-Ting Huang

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Global, regional and national burdens of cardiovascular disease attributable to secondhand smoke from 1990–2019: an age-period-cohort analysis by Hong Jiang, Xiang-Bin Pan, Xiaofei Li, Shouzheng Wang, Zeye Liu, Peijian Wei, Fengwen Zhang, Wen-Bin Ou-yang

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Korean patients with hereditary cancer: a prospective multicentre cohort study protocol exploring psychosocial and health outcomes by Boyoung Park, Sun-young Kong, Dongju Won, Jong Eun Park, Jun-Kyu Kim, Mi-Ae Jang, Jung-Sook Ha, Kyoung-Bo Kim

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PROSPECTS FOR THE DEVELOPMENT OF BIODIESEL PRODUCTION IN UKRAINE WITH CONSIDERATION OF SOCIO-ECONOMIC AND ENVIRONMENTAL EFFICIENCY by Ihor Kupchuk, Tatiana Yemchyk, Yaroslav Gontaruk

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Liver transcriptome analysis reveals PSC-attributed gene set associated with fibrosis progression by Alena Laschtowitz, Eric L. Lindberg, Anna-Maria Liebhoff, Laura Anne Liebig, Christian Casar, Silja Steinmann, Adrien Guillot, Jun Xu, Dorothee Schwinge, Michael Trauner, Ansgar Wilhelm Lohse, Stefan Bonn, Norbert Hübner, Christoph Schramm

“…Cell type specificity assignment of those genes by using published single-cell RNA-Seq data revealed genetic disease drivers expressed by cholangiocytes (e.g. …”
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A broad assessment of forty-one skin phenotypes reveals complex dimensions of skin ageing by Jun Yan Ng, Qi Yi Ambrose Wong, Jun Jie Lim, Dingyu Cen, Jia Yi Karen Wong, Yi Ying Eliza Lim, Yang Yie Sio, Kavita Reginald, Yee-How Say, Fook Tim Chew

“…Despite this diversity in skin ageing phenotypes, literature published to date is limited in scope, as many research studies either focus on one single phenotype or just a few specific phenotypes. …”
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Russian Non-Interventional Study of the Efficacy and Tolerability of Rifaximin-α Therapy in Patients with Uncomplicated Diverticular Disease under the Conditions of Outpatient Prac... by O. S. Shifrin, E. A. Poluektova, A. V. Korolev, T. I. Semenova, M. V. Shein, G. N. Leksikova, O. A. Tokareva, O. E. Davydova, P. S. Andreev, S. E. Katorkin, A. A. Chernov, A. V. Zhuravlev, O. S. Sek, A. A. Kopina, N. Yu. Samokhina, Yu. V. Gorozhankina, M. F. Samigullin, V. S. Groshilin, E. N. Borisova, T. A. Petrova, I. Yu. Pirogova, S. V. Mednikov, N. V. Smagin, A. S. Sarsenbaeva, N. V. Smirnova, L. G. Kirsanova, N. M. Malyutina, M. A. Smirnova, E. N. Shleikova, V. T. Ivashkin

“…The data obtained confirm the previously published results of randomized controlled trials on the efficacy and safety of rifaximin-α in UDD.…”
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Anxiety and depression in people with epilepsy during and one year after the COVID‐19 pandemic by Iris E. Martínez‐Juárez, Jimena Gonzalez‐Salido, Jimena Colado‐Martinez, Irving Fuentes‐Calvo, Santiago Philibert‐Rosas, E. Rodrigo Velásquez‐Coria, Salvador Martínez‐Medina, Mijail A. Rivas‐Cruz, Eithel Valenzuela‐Mendivil, Karen E. Guzmán‐Sánchez, Elizabeth M. Ruiz‐Peñaflor, Arnold R. Thomson‐Cerna, Emilia M. González‐Villagómez, Jimena Armenta‐Báez, Andrea Santos‐Peyret, Aurelio Jara‐Prado, Adriana Ochoa‐Morales, Daniel Crail‐Meléndez, Ángel Ruiz‐Chow, Mario A. Sebastián‐Díaz

“…Significance Comparing these findings with a previously published paper by our group showed a significant increase in both depression and anxiety, which were already prevalent in the earlier study. …”
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Survey of Firearm Storage Practices and Preferences Among Parents and Caregivers of Children by Meredith B. Haag, Catlin H. Dennis, Steven McGaughey, Tess A. Gilbert, Susan DeFrancesco, Adrienne R. Gallardo, Benjamin D. Hoffman, Kathleen F. Carlson

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Modelling of the closed equilibrium system H2O–(CO2)W–CaCO3–NaH2PO4 for wastewater treatment applications by Ivar Zekker, Oleg Artemchuk, Ergo Rikmann, Kalev Uiga, Laura Daija, Faysal-Al Mamun, Andrejs E. Krauklis, Ruta Ozola-Davidane, Taavo Tenno, Toomas Tenno†

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Impaired RelA signaling and lipid metabolism dysregulation in hepatocytes: driving forces in the progression of metabolic dysfunction-associated steatotic liver disease by Yihuai He, Jinlian Jiang, Lili Ou, Yunfen Chen, Aikedaimu Abudukeremu, Guimei Chen, Weiwei Zhong, Zhigang Jiang, Nuerbiye Nuermaimaiti, Yaqun Guan

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Association between the use of daily injury risk estimation feedback (I-REF) based on machine learning techniques and injuries in athletics (track and field): results of a prospect... by Karsten Hollander, David Blanco, Pascal Edouard, Laurent Navarro, Antoine Bruneau, Alexis Ruffault, Joris Chapon, Pierre-Eddy Dandrieux, Christophe Ley, Spyridon (Spyros) Iatropoulos

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Targeting sphingosine 1-phosphate receptor 3 inhibits T-cell exhaustion and regulates recruitment of proinflammatory macrophages to improve antitumor efficacy of CAR-T cells agains... by Weiting Liao, Ge Gao, Xia He, Pei Shu, Qizhi Ma, Benxia Zhang, Diyuan Qin, Yongsheng Wang

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Hydrogen and hydrogen sulphide in volcanic gases: abundance, processes, and atmospheric fluxes by Aiuppa, Alessandro, Moussallam, Yves

“…Finally, by using our volcanic gas dataset in tandem with recently published global volcanic SO$_{2}$ and CO$_{2}$ budgets, we provide refined estimates for total H$_{2}$S (median, 1.4 Tg/yr; range, 0.9–8.8 Tg/yr) and H$_{2}$ (median, 0.23 Tg/yr; range, 0.06–1 Tg/yr) fluxes from global subaerial volcanism.…”
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Modeling resistive-inductive evolution of currents in Wendelstein 7-X by L. van Ham, S.A. Lazerson, J.C. Schmitt, B.F. Lee, M. Beurskens, K.J. Brunner, N. Chaudhary, G. Fuchert, J. Geiger, M. Hirsch, J. Knauer, A. Langenberg, J.W. Oosterbeek, N. Pablant, E. Pasch, K. Rahbarnia, G. Weir, the W7-X Team

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