High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and Phospholipidosis by Arvind Pradip, Daniella Steel, Susanna Jacobsson, Gustav Holmgren, Magnus Ingelman-Sundberg, Peter Sartipy, Petter Björquist, Inger Johansson, Josefina Edsbagge

“…The different parameters measured were detected at subcytotoxic concentrations and the order of which the compounds were categorized (as severe, moderate, mild, or nontoxic) based on the degree of injury at isomolar concentration corresponded to previously published data. Taken together, the present study shows how hiPSC derived hepatocytes can be used as a platform for screening drug induced hepatotoxicity by HCA.…”
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A bibliometric study on organization citizenship behavior for the environment by M.M. Sulphey, N.S. AlKahtani, N.A.M. Senan, A.H.E. Adow

“…Over the past decade, 187 articles have been published on this topic. In the same period, the term organization citizenship behavior for the environment was found to be a keyword used 54 times. …”
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Large Language Models in Dental Licensing Examinations: Systematic Review and Meta-Analysis by Mingxin Liu, Tsuyoshi Okuhara, Wenbo Huang, Atsushi Ogihara, Hikari Sophia Nagao, Hiroko Okada, Takahiro Kiuchi

“…Methods: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a comprehensive search across PubMed, Web of Science, and Scopus for studies published from 1 January 2022 to 1 May 2024. Two authors independently reviewed the literature based on the inclusion and exclusion criteria, extracted data, and evaluated the quality of the studies in accordance with the Quality Assessment of Diagnostic Accuracy Studies-2. …”
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Beyond COVID-19, the case for collecting, analysing and using sex-disaggregated data and gendered data to inform outbreak response: a scoping review by Simone E Carter, Shirin Heidari, Leah Zilversmit Pao, Marie-Amelie Degail, Marie Meudec, McKinzie Gales, Emelie Love Yonally Phillips, Christine Dubray, Clara Rodriguez Ribas Elizalde, M Ruby Siddiqui

“…A scoping review was conducted to provide an overview of the extent of sex-disaggregated data and gender analysis in outbreak response within low- and middle-income countries (LMICs).Methods Five databases were searched for peer-reviewed literature examining sex- and gender-specific outcomes for communicable disease outbreaks published in English between 1 January 2012 and 12 April 2022. …”
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Genomic Characterization and Functional Validation of Six <i>cis</i>-Regulatory Sequences in Medicinal Plant <i>Andrographis paniculata</i> by Xingbin Lv, Hua Yang, Yufang Hu, Qi Liang, Shuyun Tian, Lang Yang, Mingkun Huang, Ling Zhang, Yanqin Xu

“…In this study, we provided a comprehensive analysis of the published genomic data of <i>Andrographis paniculata</i> and identified six candidate <i>ApACRs</i>. …”
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Filling the data gap on CGRP mAb therapy in low- to middle-income countries in Southeast Asia: insights from a real-world study in Thailand by Prakit Anukoolwittaya, Akarin Hiransuthikul, Thanakit Pongpitakmetha, Sekh Thanprasertsuk, Wanakorn Rattanawong

“…Abstract Background Most real-world data on CGRP mAbs have been published from high-income countries such as the USA, Western countries, Japan, Korea, and Singapore. …”
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A Case of Nonfunctioning Pituitary Carcinoma That Responded to Temozolomide Treatment by Haruko Morokuma, Takao Ando, Takuya Hayashida, Ichiro Horie, Naoko Inoshita, Fumi Murata, Ikuko Ueki, Kan Nakamura, Misa Imaizumi, Toshiro Usa, Atsushi Kawakami

“…The alkylating reagent temozolomide (TMZ) was recently shown to be effective as a treatment for pituitary carcinoma. Most of the published reports of TMZ use in pituitary carcinoma cases were against hormone-producing carcinomas. …”
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Long term cost-effectiveness analysis of IDegLira in the treatment of type 2 diabetes patients compared to GLP-1RA added to basal insulin after IDegLira entered the national reimbu... by Dunming Xiao, Junling Weng, Lei Zhang, Chang Xing, Yan Wei, Yingyao Chen

“…Other cost and utility data are sourced from published literature. The health outcome indicator is quality-adjusted life years (QALYs). …”
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The effect of acute sleep deprivation on cortisol level: a systematic review and meta-analysis by Yifei Chen, Wenhui Xu, Yiru Chen, Jiayu Gong, Yanyan Wu, Shutong Chen, Yuan He, Haitao Yu, Lin Xie

“…The PubMed, Web of Science, EMBASE, CLINAHL and Cochrane databases were searched for eligible studies published up to June 7, 2023. All analyses were performed using Review Manager 5.4 and Stata/SE 14.0. …”
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Scoping review to identify strategies and interventions improving interprofessional collaboration and integration in primary care by Roy Remmen, Kris Van den Broeck, Peter Pype, Peter Van Bogaert, Muhammed Mustafa Sirimsi, Hans De Loof, Kristel De Vliegher

“…Articles were included if they: (1) were in English, (2) described an intervention to improve IPCI in primary care involving at least two different healthcare disciplines, (3) originated from a high-income country, (4) were peer-reviewed and (5) were published between 2001 and 2020.Data extraction and synthesis From each paper, eligible data were extracted, and the selected papers were analysed inductively. …”
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Leveraging Real-World Evidence to Define Severe RSV Lower Respiratory Tract Disease in Adults by Catherine A. Panozzo, Edward E. Walsh, Zhen Yang, Eleanor Wilson, Jaya Goswami, Sonia K. Stoszek, Adrianna Loback, Tony Ng, Beverly M. Francis, Alana K. Simorellis, Wenmei Huang, Linwei Li, Rebecca Vislay-Wade, Zhe Zheng, Evan J. Anderson, Allison August, Grace Chen, Ann R. Falsey

“…Abstract Introduction As no standard case definitions for respiratory syncytial virus—associated lower respiratory tract disease (RSV-LRTD) in adults are available, this study analyzed definitions for severe RSV-LRTD from previously published data in hospital and community cohorts of adults with RSV–associated symptoms. …”
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Bilateral prophylactic mastectomy: should we preserve the pectoral fascia? Protocol of a Dutch double blinded, prospective, randomised controlled pilot study with a within-subject... by Cornelis Verhoef, Linetta B Koppert, Marloes E Clarijs, Laurentine S E van Egdom, Dalibor Vasilic, T. van Dalen, C. de Betue, J. Rothbarth, E.V.E. Madsen, L.M. Beelen, M.A.M. Mureau, E.M.L. Corten, A.J.M. Luijsterburg, M.J. Hop, H.M. Zuijdendorp, N.A.S. Posch, C.M.C.A. van Laarhoven, M. de Kraker

“…Results will be presented during international conferences and published in a peer-reviewed academic journal.Trial registration number NCT05391763; clinicaltrials.gov…”
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Vision impairment and differential access to eye health services in Aotearoa New Zealand: a scoping review by Matire Harwood, Jacqueline Ramke, Joanna Black, Himal Kandel, Jaymie Tingkham Rogers, Ben Wilkinson

“…We mapped 72 outcomes, many of which were access-related (n=32), published since 2000 (n=28) and largely focused on diabetic retinopathy (n=21) or cataract (n=13) in facility-based settings (n=18). …”
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Association between elevated cystatin C levels and obstructive sleep apnea hypopnea syndrome: a systematic review and updated meta-analysis by Nianying Fu, Xiaotao Tan, Jie He

“…Methods A thorough search was undertaken across various medical databases, namely PubMed, CNKI, EMBASE, Web of Science, and WanFang, until October 1, 2024, to determine published articles pertinent to OSAHS. The present research conducted a comprehensive review of the literature concerning cystatin C levels in both patients with OSAHS and controls, variations in cystatin C levels pre-and post-surgery/CPAP treatment, the Pearson/Spearman correlation coefficients between cystatin C levels and sleep monitoring indices, and the hazard ratio (HR) associated with cystatin C levels concerning the onset of cardiovascular and cerebrovascular diseases among patients with OSAHS. …”
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Evaluation of Rivaroxaban Exposure via Anti-Xa Levels During VTE Prophylaxis in Hospitalized Patients by Kaitlin Blotske PharmD, Toral Patel PharmD, BCPS, Toby Trujillo PharmD, FCCP, FAHA, BCPS, Matthew Marlar MLS (ASCP), Stuart Lind MD, Henry Kramer MD, Kathryn Hassell MD, Tyree H. Kiser PharmD, FCCM, FCCP, BCCCP, BCPS

“…Rivaroxaban was FDA-approved in 2019 for venous thromboembolism (VTE) prophylaxis in acutely ill hospitalized patients. Little to no published data is available to determine the level of correlation between rivaroxaban drug concentration and UFH/LMWH calibrated anti-Xa assays at VTE prophylactic doses of rivaroxaban 10 mg daily. …”
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Roman gems and finger-rings made of gold and glass from Nicea in Bithynia (south-eastern Marmara) by Fatih Hakan Kaya, Ergün Laflı, Martin Henig, Musa Albayrak

“…These objects are significant as very few gemstones have been published from Bithynia. Two of the finds were excavated from a necropolis area of Nicaea. …”
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Minimum elements for reporting a feasibility assessment of algorithms based on routinely collected health data for multi-jurisdiction use: Health Data Research Network Canada recom... by Naomi Hamm, Sharon Bartholomew, Yinshan Zhao, Sandra Peterson, Saeed Al-Azazi, Kimberlyn McGrail, Lisa Lix

“…The subcommittee reviewed items within the STROBE and RECORD guidelines and evaluated these items against published feasibility studies. Items to ensure transparent reporting of feasibility studies not contained within STROBE or RECORD guidelines were identified through consensus by subcommittee members using the Nominal Group Technique. …”
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“But how true that is, I do not know”: the influence of written sources on the medicinal use of fungi across the western borderlands of the former Soviet Union by Julia Prakofjewa, Matteo Sartori, Raivo Kalle, Łukasz Łuczaj, Małgorzata Karbarz, Giulia Mattalia, Povilas Šarka, Baiba Prūse, Nataliya Stryamets, Martin Anegg, Natalia Kuznetsova, Valeria Kolosova, Olga Belichenko, Muhammad Abdul Aziz, Andrea Pieroni, Renata Sõukand

“…The highest numbers of medicinal uses were documented in Russia, Estonia and Ukraine. Studies published before the Soviet era listed 21 fungal taxa and one lichen species used in the study region. …”
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Association of Matrix Metalloproteinase 9 (MMP-9) Polymorphisms with Asthma Risk: A Meta-Analysis by Fenfang Zou, Jianpeng Zhang, Guoan Xiang, Hongbin Jiao, Hongmei Gao

“…Published data on the association between MMP-9 polymorphisms (−1562 C > T, rs3918242; Gln279Arg, rs17576 Arg668Gln, rs17577) and asthma susceptibility are inconclusive. …”
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Effectiveness of chain of survival for out-of-hospital-cardiac-arrest (OHCA) in resource limited countries: A systematic review by Mirza Noor Ali Baig, Zafar Fatmi, Nadeem Ullah Khan, Uzma Rahim Khan, Ahmed Raheem, Junaid Abdul Razzak

“…Methods: This systematic review, following PRISMA guidelines, included observational and interventional studies on OHCA management from low, lower-middle, and upper-middle-income countries, published in English (2004–2023). PubMed, Embase, CINAHL, and Cochrane Library were searched using predefined terms. …”
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