Cardiovascular risk associated with glucagon-like peptide-1 receptor agonists versus other conventional glucose-lowering drugs in patients with type-2 diabetes: protocol for a nati... by François Schiele, Mikael Mazighi, Nicolas Danchin, Igor Sibon, Gilles Lemesle, Kamel Mohammedi, Laurent Fauchier, Bruno Detournay, Alexandre Caron, Corinne Emery, Camille Nevoret, Lucile Vigié, Christine Massien

“…The findings of this study will be published in peer-reviewed scientific journals and presented at international conferences.Trial registration number F20220803152803.…”
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Bibliometric analysis of laryngeal cancer treatment literature (2003–2023) by Yan Zhao, Jiancheng Xue

“…Results: The analysis showed that 760 theoretical works and review papers were published in 96 academic journals by 4210 authors from 1148 institutions across 60 countries/regions. …”
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Effectiveness of the Modified WHO Labour Care Guide to Detect Prolonged and Obstructed Labour Among Women Admitted at Eight Publicly Funded, Midwife-Led Community Health Facilities... by Mugyenyi GR, Tumuhimbise W, Atukunda EC, Tibaijuka L, Ngonzi J, Kayondo M, Kanyesigye M, Musimenta A, Yarine FT, Byamugisha JK

“…More controlled and powered studies should evaluate the two tools in different facilities and sub-populations.Trial Registration: This trial registration was registered with clinical trials.gov number NCT05979194 on 2023-08-07, and the protocol was published by BMJ open, as 10.1136/bmjopen-2023-079216 on 15 April 2024.21 Trial registration number NCT05979194 clinical trials.gov.Keywords: modified WHO LCG, partograph, effectiveness, labour monitoring, ambispective cohort study, Uganda…”
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Investigation on the current situation of research and development capacity of ICU specialist nurses in Guangxi, China (广西壮族自治区ICU专科护士科研和发展能力现状调查)... by HUANG Yingqiong (黄映琼), JIANG Li (蒋莉), TIAN Weiyi (田韦毅), MO Jinli (莫金莉), ZHANG Yun (张云), NING Chuanyi (宁传艺)

“…Results A total of 192 ICU specialist nurses were surveyed, 122 (63. 54%) had published papers, 45 (23. 44%) were the leading researcher of the project, 77 (40. 10%) had obtained patents; 51 (26. 56%) had participated in consultations, and 133 (69. 27%) had obtained specialist nurse certificates and then attended continuing education training. …”
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Neurological manifestations associated with COVID-19 vaccine by R. Alonso Castillo, J.C. Martínez Castrillo

“…The most frequently reported adverse events were Bell’s palsy 4936/13 809 (35.7%), headache (4067/13 809), cerebrovascular events 2412/13 809 (17.47%), Guillain-Barré syndrome 868/13 809 (6.28%), central nervous system demyelination 258/13 809 (1.86%) and functional neurological disorder 398/13 809 (2.88%). Most of the published cases occurred in temporal association with the Pfizer vaccine (BNT162b2), followed by the AstraZeneca vaccine (ChAdOX1-S). …”
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The History of Miss Jane Pittman by Christopher Mulvey

“…Brown, A Fugitive Slave Written by Himself, published in 1847, will show how close these links are. …”
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Etelcalcetide: What we know eight years since its approval by Pedro Freitas, Luciano Pereira

“…This narrative review aims to summarize the published data about etelcalcetide, focusing on biochemical, cardiovascular (CV) and bone endpoints, as well as adverse effects and all-cause mortality. …”
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The intellectual paradigm and scientific mapping of brand image in International Researches by Maryam Najafi Yazdi, Seyed Hassan Hataminasab, Shahnaz Nayebzadeh

“…In this regard, the researcher conducted a systematic study of research articles published between 1977 and 2023 and used VOS Viewer software version 1.6.20 for scientific analysis. …”
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Resilience Based on Community-Oriented Capacities in Crisis Conditions by Mohammad Jalali, Mahdi Mahmoodzadeh Vashan, Nour Mohammad Yaghoubi, Mohammad Mohammadi

“…Therefore, the current research seeks to identify the factors affecting resilience based on community-oriented capacities in crisis situations using the meta-synthesis method and finally presenting a model in this field.Case studyThe statistical population of this research includes all articles published in domestic and foreign scientific databases between 2000 and 2023, and finally 56 studies that were closely related to the subject under study were selected as a sample.Materials and Methods The research is of an applied type with an exploratory nature, in order to collect data, a meta-synthesis method was used. …”
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Recent advances in systemic therapy for advanced biliary tract cancer: A systematic review and meta-analysis using reconstructed RCT survival data by Zhihao Li, Daniel Aliseda, Owen Jones, Luckshi Rajendran, Christian Magyar, Robert Grant, Grainne M. O’Kane, Anna Saborowski, Gonzalo Sapisochin, Arndt Vogel

“…Methods: Our systematic review included studies from five databases focusing on English-language articles published between January 2010 and June 2024. We included randomized clinical trials (RCTs) that featured GemCis in a treatment arm for treatment-naive adults with advanced BTCs. …”
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The role of smell in medical and psychological disorders: An interdisciplinary approach by Giuseppe Riva

“…In the past decade, many studies on olfactory function have been published. The sense of smell has been underestimated for years, until its role has been rediscovered and more deeply analyzed. …”

Protocol for a phase IV double-blind randomised controlled trial to investigate the effect of the 13-valent pneumococcal conjugate vaccine and the 23-valent pneumococcal polysaccha... by Tao Chen, Duolao Wang, Konstantinos Liatsikos, Stephen B Gordon, Hassan Burhan, Ben Morton, Tinashe K Nyazika, Bradford D Gessner, Helen Hill, Andrea Collins, Josh Hamilton, Kelly Davies, Fred Fyles, Phoebe Hazenberg, Elizabeth Begier, Angela Hyder-Wright, Sherin Pojar, Christopher Myerscough, Jesus Reine, Ryan E Robinson, Britta Urban, Elena Mitsi, Carla Solorzano, Angela Quinn, Kaijie Pan, Annaliesa S Anderson, Christian Theilacker, Daniela M Ferreira, Kelly Convey, James Court, Madlen Farrar, Lisa Hitchins, Ashleigh Howard, Lauren Kerruish, Samuel Latham, Annabel Murphy, Elissavet Nikolaou, Angelina Peterson

“…Furthermore, we will explore the immune responses associated with these vaccines, their effect on colonisation and the relationship between colonisation and urinary pneumococcal antigen detection.Ethics and dissemination The study is approved by the NHS Research and Ethics Committee (Reference: 20/NW/0097) and by the Medicines and Healthcare products Regulatory Agency (Reference: CTA 25753/0001/001–0001). Findings will be published in peer-reviewed journals.Trial registration number ISRCTN15728847, NCT04974294.…”
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Haplotype Analysis of Candidate Genes Involved in Inflammation and Oxidative Stress and the Susceptibility to Preeclampsia by Aiping Chen, Huifang Zhao, Jingli Wang, Ru Zhang, Jingjing Liu, Xin Zhao, Congying Li, Xuewen Jia, Xueying Li, Yan Lin, Mingzhen Guo, Sai Li, Chao Liu, Yuan Li, Shiguo Liu

“…Unbalanced inflammatory reactions and oxidative stress are inseparably interconnected, and both may play crucial roles in the pathophysiological mechanisms of preeclampsia (PE). In the published previous studies, we have genotyped for SNPs that related to inflammation (rs2227485, rs153109, rs17855750, rs2027432, rs2275913, rs763780, rs4819554, and rs13015714) and oxidative stress (rs1695, rs4680, rs1800566, rs4807542, rs713041, rs7579, rs230813, rs1004467, rs3824755, and rs9932581) to investigate whether these polymorphisms were associated with susceptibility to PE in a Chinese Han population. …”
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NEUROlogical Prognosis After Cardiac Arrest in Kids (NEUROPACK) study: protocol for a prospective multicentre clinical prediction model derivation and validation study in children... by Elizabeth S Draper, John Pappachan, Kent Thorburn, David Inwald, Richard Feltbower, Buvana Dwarakanathan, Patrick Davies, Kate Penny-Thomas, James Martin, Rum Thomas, Kevin P Morris, Roger Parslow, Timothy Thiruchelvam, Sophie Skellett, Hari Krishnan Kanthimathinathan, Victoria Hiley, Peter Barry, Sian Cooper, Rohit Saxena, Cormac Breatnach, Barnaby Robert Scholefield, Sarah Evans, Mirjam Kool, Alice J Sitch, Fang Smith, Yamuna Thiru, Richard Levin, Rachel Agbecko, James Weitz, Akash Deep, Sandra Gala-Peralta, Milly Lo, Rachael Barber, Stewart Reid, Siva Oruganti, Kalai Sadasivam, Mark Bebbington

“…The results of this study will be published in peer-reviewed journals and presented in conferences.Trial registration number NCT03574025.…”
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Distinct immune cell infiltration patterns in pancreatic ductal adenocarcinoma (PDAC) exhibit divergent immune cell selection and immunosuppressive mechanisms by Shivan Sivakumar, Ashwin Jainarayanan, Edward Arbe-Barnes, Piyush Kumar Sharma, Maire Ni Leathlobhair, Sakina Amin, David J. Reiss, Lara Heij, Samarth Hegde, Assaf Magen, Felicia Tucci, Bo Sun, Shihong Wu, Nithishwer Mouroug Anand, Hubert Slawinski, Santiago Revale, Isar Nassiri, Jonathon Webber, Gerard D. Hoeltzel, Adam E. Frampton, Georg Wiltberger, Ulf Neumann, Philip Charlton, Laura Spiers, Tim Elliott, Maria Wang, Suzana Couto, Thomas Lila, Pallavur V. Sivakumar, Alexander V. Ratushny, Mark R. Middleton, Dimitra Peppa, Benjamin Fairfax, Miriam Merad, Michael L. Dustin, Enas Abu-Shah, Rachael Bashford-Rogers

“…A comprehensive analysis of single-cell multi-omic data from matched tumour-infiltrated CD45+ cells and peripheral blood in 12 patients, and two published datasets, reveals a complex immune infiltrate. …”
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TRACE Model: Predicting Treatment Response to Transarterial Chemoembolization in Unresectable Hepatocellular Carcinoma by Wang W, Zhang Q, Cui Y, Zhang S, Li B, Xia T, Song Y, Zhou S, Ye F, Xiao W, Cao K, Chi Y, Qu J, Zhou G, Chen Z, Zhang T, Chen X, Ju S, Wang YC

“…In contrast, none of the published scoring systems, including ART, SNACOR or ABCR score, demonstrated significant differences between the risk groups in OS prediction.Conclusion: The TRACE model exhibited favorable predictive capability for six-month TACE response, and holds potential as a marker for long-term survival outcomes.Keywords: hepatocellular carcinoma, treatment response, transarterial chemoembolization, radiomics…”
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Effects of non-pharmacological interventions on the depressive outcomes in people with mild cognitive impairment: an overview of systematic reviews by Chen Yaxin, Chen Yaxin, Yan Lijiao, Chen Zhao, Hu Ziteng, Zhang Fuqiang, Liu Zhenhong, Feng Luda, Li Yixiang, Dai Xiangwei, Che Qianzi, Li Huizhen, Zhang Haili, Liang Ning, Shi Nannan

“…ObjectiveThis study aimed to summarize and assess the certainty of evidence of non-pharmacological interventions (NPIs) on the depressive outcomes in people with mild cognitive impairment (MCI) based on published systematic reviews (SRs).MethodDatabases including PubMed, EMBASE, PsycINFO, the Cochrane Database of Systematic Reviews, CNKI, CBM, Wanfang and VIP database were searched from their inception to June 6, 2023. …”
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Intimate partner violence among women of reproductive age during the COVID-19 pandemic in Ethiopia: a systematic review and meta-analysis by Gizachew Yilak, Alemayehu Sayih Belay, Aychew Kassie, Befkad Derese Tilahun, Ambaw Abebaw Emrie, Mulat Ayele, Eyob Shitie Lake, Legese Fekede Abza

“…Therefore, this study aimed to assess the pooled prevalence of IPV and its determinants among women of reproductive age during the COVID-19 pandemic in Ethiopia.Design Systematic review and meta-analysis.Data sources The review was done as per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline using different search databases such as: PubMed/Medline, Cochrane Library, Virtual Health Library Regional Portal, HINARI (research4life), and Google Scholar.Eligibility criteria Those quantitative studies conducted in Ethiopia during the COVID-19 pandemic, that reported the prevalence of IPV among women of reproductive age, and were published in English from 13 March 2020 to 15 October 2025, were included for this study.Data extraction and synthesis All authors independently extracted data using the Joanna Briggs Institute manual for evidence synthesis. …”
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Genetic testing of ocular manifestations of proliferative syndrome to provide pathophysiology-oriented treatment by M.E. Weener, N.A. Bakunina, J.M. Salmasi, G.V. Poryadin, D. Barh, Yu.D. Kuznetsova, L.M. Balashova

“…We summarize relevant published data and our 5-year experience in searching treatment tools for excessive non-productive proliferation.…”
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Development and validation of a model to predict cognitive impairment in traumatic brain injury patients: a prospective observational studyResearch in context by Xiaofang Yuan, Qingrong Xu, Fengxia Du, Xiaoxia Gao, Jing Guo, Jianan Zhang, Yehuan Wu, Zhongkai Zhou, Youjia Yu, Yi Zhang

“…These patients were selected from our previously published studies. Baseline characteristics, medical history, clinical TBI characteristics, treatment details, and vital signs during hospitalization were screened via least absolute shrinkage and selection operator (LASSO) and logistic regression to construct a predictive net risk score. …”
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