Enhanced adherence counselling completion rates, viral load suppression in people with HIV in Africa: systematic review and meta-analysis by Hafidha M. Bakari, Oluwafemi Alo, Mariam S. Mbwana, Swalehe M. Salim, Zuhura M. Ally, Rahma Musoke, Emilie Ludeman, Taylor Lascko, Natalia Blanco, Habib O. Ramadhani

“…Methods Through systematic review, PubMed, Embase, Cochrane CENTRAL and clinicaltrials.gov were searched for articles published between January 2016 and December 2022. Participants who attended three EAC sessions were considered to have completed and VLS was defined as HIV-RNA < 1000 copies/ml. …”
Get full text

‘What a perennial delight is in hearing the French language spoken!’: Class, Language and Taste in the Maison de Molière’s French Performances in London (1871–1893) by Ignacio Ramos Gay

“…Through an examination of the reviews and impressions published by an array of professionals, including leading theatre critics at the time, dramatists, actors and aficionados, the research analyses the sociological, political, and aesthetic implications associated with the firm presence of the French language and French canonical plays in late Victorian London. …”
Get full text

Long-Covid in Children and Adolescents: Clinical Challenges and Treatment Perspectives by Kornelia Karamus, Rafał Rejamak, Jan Biłogras, Martyna Borowska-Łygan, Konrad Strużek, Wojciech Urban, Jakub Tomaszewski

“…Materials and Methods: The review includes works published between 2020 and 2024, available in the PubMed database, identified using relevant keywords, as well as the WHO publication "World Health Organization. …”
Get full text

Treat-to-target strategy with secukinumab as a first-line biological disease modifying anti-rheumatic drug compared to standard-of-care treatment in patients with active axial spon... by Xenofon Baraliakos, Denis Poddubnyy, Ludwig Hammel, Marvin Heyne, Justyna Veit, Claudia Jentzsch

“…The first results are expected to be published in early 2022.Trial registration number This study is registered with ClinicalTrials.gov, NCT03906136.…”
Get full text

Optimal Suppression of Photocatalytic Activity of Hybrid TiO2 Particles in Epoxy Thin Film by Using Taguchi Method by Sunderishwary S. Muniandy, Tan Sek Soon, Swee Yong Pung, Sivakumar Ramakrishnan

“…Copyright © 2024 by Authors, Published by BCREC Publishing Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).…”
Get full text

BreathCarer: Informal carers of patients with chronic breathlessness: a mixed-methods systematic review of burden, needs, coping, and support interventions by Saskia Blütgen, Anne Pralong, Carolin Wilharm, Yvonne Eisenmann, Raymond Voltz, Steffen T. Simon

“…Review methods The mixed-methods review included any study on burden, needs and coping among carers of patients with breathlessness published from the inception of the databases until July 2023. …”
Get full text

A Novel Liquid Chromatography–Tandem Mass Spectrometry Method to Quantify Tryptophan and Its Major Metabolites in Serum to Support Biomarker Studies in Patients with Cancer Undergo... by Anna Siemiątkowska, Barbara Kuźnar-Kamińska, Katarzyna Kosicka-Noworzyń, Kamila Nowaczewska, Hanna Winiarska, Dominika Popiołek, Filip Kamiński, Franciszek K. Główka

“…One of them was the phenomenon of cross-interferences between the analyzed molecules, which has not been explored in most published papers. We noticed that injecting a pure single-compound solution often generated a signal in the other compounds’ MS/MS channels. …”
Get full text

Altered Mitochondrial Respiration and Other Features of Mitochondrial Function in Parkin-Mutant Fibroblasts from Parkinson’s Disease Patients by William Haylett, Chrisna Swart, Francois van der Westhuizen, Hayley van Dyk, Lize van der Merwe, Celia van der Merwe, Ben Loos, Jonathan Carr, Craig Kinnear, Soraya Bardien

“…Human cellular models with parkin null mutations are particularly valuable for investigating the mitochondrial functions of parkin. However, published results reporting on patient-derived parkin-mutant fibroblasts have been inconsistent. …”
Get full text

Evaluating the Effect of Chloroform and Water Extract of Satureja khuzistanica on the Expression of Bcl-2 and Bax in Gastric Cancer Cell Line by Bagher Biglak, Asghar Tanomand, Leyla Açik, Farzad Arjomandi Rad, Gholamreza Shahsavari, Saman Kazemi, Hossein Soltanzadeh

“…Despite numerous articles published about this plant, a limited number of studies have been conducted on its anticancer effects. …”
Get full text

Efficacy of ceftazidime-avibactam with or without polymyxin for carbapenem-resistant Klebsiella pneumoniae infections after initial treatment with polymyxin by Jingli Lu, Yani Ma, Zhe Cao, Baoling Zhu, Luna Fan, Haiyang Meng

“…CAZ-AVI salvage therapy demonstrated improved survival outcomes in patients who experienced failure with polymyxin B therapy.IMPORTANCEFor patients with carbapenem-resistant Klebsiella pneumoniae (CRKP) infections, published experience with salvage therapy is limited after the failure of polymyxin-based initial therapy. …”
Get full text

自发性脑出血术后早期使用阿司匹林的可能性：来自中国学者的首个脑出血围手术期管理高级别循证依据 Possibility of Early Use of Aspirin after Spontaneous Intracerebral Hemorrhage Surgery: The First High-Level Evidence-Based Evidenc... by 周航，陈高(ZHOU Hang, CHEN Gao)

“…However, current guidelines have not yet established clear recommendations on whether or when to initiate antiplatelet therapy. The recently published early-start antiplatelet treatment after neurosurgery in patients with spontaneous intracerebral hemorrhage (E-start) study indicates that for intracerebral hemorrhage patients with a high risk of ischemic events, early initiation of postoperative antiplatelet therapy can bring significant benefits without increasing the risk of bleeding. …”
Get full text

Blood Genomics Identifies Three Subtypes of Systemic Lupus Erythematosus: “IFN-High,” “NE-High,” and “Mixed” by Mintian Cui, Taotao Li, Xinwei Yan, Chao Wang, Qi Shen, Hongbiao Ren, Liangshuang Li, Ruijie Zhang

“…Three data sets were used in this paper that were collected from the Gene Expression Omnibus (GEO) database, which contained two published data sets of pediatric and adult SLE patients (GSE65391, GSE49454) and public longitudinal data (GSE72754) from a cohort of SLE patients treated with IFN-α Kinoid (IFN-K). …”
Get full text

Burden and Determinant of Inadequate Dietary Diversity among Pregnant Women in Ethiopia: A Systematic Review and Meta-Analysis by Hagos Degefa Hidru, Meresa Berwo Mengesha, Yared Hailesilassie, Fissaha Tekulu Welay

“…The searches were restricted to articles published in the English language only, and Medical Subject Headings (MeSH terms) was used to help expand the search in advanced PubMed search. …”
Get full text

Research investigating patient and carer psychoeducation needs regarding post-stroke cognition: a scoping review by Nele Demeyere, Georgina Hobden, Faye Tabone

“…Synthesis involved descriptive statistics and thematic analysis.Results Searches identified 8115 articles, of which 30 were included. Articles were published between 1996 and 2023. Studies were conducted in Australia (n=7), USA (n=6), UK (n=5), Canada (n=3), New Zealand (n=3), Ireland (n=2), Netherlands (n=2), South Korea (n=1) and Sweden (n=1). …”
Get full text

Bright night sleeping environment induces diabetes and impaired glucose tolerance in non-human primates by Shuxing Wang, Zhenyi Chen, Zihao Liang, Qiang Xu, Jiankai Zhang

“…BackgroundAccording to the IDF Diabetes Atlas regularly published by International Diabetes Federation, the prevalence of diabetes and impaired glucose tolerance (IGT), diabetes-related mortality and health expenditure are becoming serious eventually at the global, regional and national level. …”
Get full text

Use of machine learning in osteoarthritis research: a systematic literature review by Francis Berenbaum, Jérémie Sellam, David Klatzmann, Atul J Butte, Karine Louati, Encarnita Mariotti-Ferrandiz, Marie Binvignat, Valentina Pedoia

“…For each selected article, the number of patients, ML algorithms used, type of data analysed, validation methods and data availability were collected.Results From 1148 screened articles, 46 were selected and analysed; most were published after 2017. Twelve articles were related to diagnosis, 7 to prediction, 4 to phenotyping, 12 to severity and 11 to progression. …”
Get full text

Worldwide Research Trends on Diabetic Foot Ulcers (2004–2020): Suggestions for Researchers by Pin Deng, Hongshuo Shi, Xuyue Pan, Huan Liang, Shulong Wang, Junde Wu, Wei Zhang, Fasen Huang, Xiaojie Sun, Hanjie Zhu, Zhaojun Chen

“…We performed a longitudinal review of publications over 17 years: 4500 articles and 865 review articles on DFUs published from 2004 to 2020 were analyzed. The total citation was 107,296. …”
Get full text

Meta Analysis of Efficacy and Safety of Prostate Biopsy: A Comparison Between Transperineal and Transrectal Approach by Syah Mirsya Warli, Stivano Rizky Valentino Torry, Dhirajaya Dharma Kadar, Ginanda Putra Siregar, Fauriski Febrian Prapiska

“…Approaches: a comprehensive search was carried out in PubMed, Embase, Web of Science, and Cochrane Library to locate all pertinent papers published till June 8, 2023. Data on cancer detection rate and complications after prostate biopsy were gathered and analyzed via Review Manager software. …”
Get full text

Genomic characterization of chronic lymphocytic leukemia in patients of African ancestry by Cecilia Bonolo de Campos, Chantal E. McCabe, Laura A. Bruins, Daniel R. O’Brien, Sochilt Brown, Renee C. Tschumper, Cristine Allmer, Yuan Xiao Zhu, Kari G. Rabe, Sameer A. Parikh, Neil E. Kay, Huihuang Yan, James R. Cerhan, John N. Allan, Richard R. Furman, J. Brice Weinberg, Danielle M. Brander, Diane F. Jelinek, Marta Chesi, Susan L. Slager, Esteban Braggio

“…Abstract Despite the considerable effort to characterize the genomic landscape of chronic lymphocytic leukemia (CLL), published data have been almost exclusively derived from patients of European Ancestry (EA), with significant underrepresentation of minorities, including patients of African Ancestry (AA). …”
Get full text

Enhancing patient engagement: the influence of an in-consult patient decision aid on shared decision-making for lung tumour radiation – protocol for the randomised trial ‘SDM Lung... by Karina Dahl Steffensen, Signe Timm, Torben Frøstrup Hansen, Thomas Leth Fink, Charlotte Kristiansen, Torben Schjødt Hansen, Rune Slot Thing

“…Results from this study will be presented at scientific meetings and published in English peer-reviewed journals.Trial registration number ClinicalTrials.gov (NCT04940936).…”
Get full text