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Methods to address functional unblinding of raters in CNS trials
Published 2025-02-01“…Two different methods were used to examine possible functional unblinding in pooled data from three recent five-week, double-blind, placebo-controlled trials of xanomeline and trospium chloride (formerly known as KarXT) in participants with schizophrenia experiencing acute psychosis. Xanomeline/trospium is an M1/M4 muscarinic receptor agonist that may produce cholinergic side effects. …”
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242
Blinded by the Mind: Exploring the Hidden Psychiatric Burden in Glaucoma Patients
Published 2025-01-01“…Other less frequent but still significant conditions like sleep disorders, psychosis, dementia, and post-traumatic stress disorder were also observed. …”
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243
General practice database on mortality in adults on methylphenidate: cohort study
Published 2022-08-01“…Additional adjustment was performed for the intervention (‘intention-to-treat’).Results Although during follow-up, the unadjusted risks of depression and suicide attempt were strongly increased in users, depression and psychosis became non-significant after adjustment for alcohol-abuse and substance-abuse and psychiatric disease in the medical history and after adjustment for ‘intention-to-treat’. …”
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244
Effectiveness of cognitive–behavioural therapy: a protocol for an overview of systematic reviews and meta-analyses
Published 2018-12-01“…The outcomes of interest include: health-related quality of life, depression, anxiety, psychosis and physical/physiological outcomes prioritised in the individual reviews. …”
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245
A case report of exacerbation of extrapyramidal symptoms following the switch from risperidone to paliperidone during valproate therapy
Published 2025-01-01“…We report a case of a 48-year-old Japanese male with epilepsy-associated psychosis and mild intellectual disability who experienced severe EPS during a gradual cross-titration from risperidone to paliperidone while on valproate therapy. …”
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246
Prevalence and patient characteristics associated with cardiovascular disease risk factor screening in UK primary care for people with severe mental illness: an electronic healthca...
Published 2025-01-01“…Background People with severe mental illness (SMI) are at increased risk of cardiovascular disease (CVD), and initiatives for CVD risk factor screening in the UK have not reduced disparities.Objectives To describe the annual screening prevalence for CVD risk factors in people with SMI from April 2000 to March 2018, and to identify factors associated with receiving no screening and regular screening.Methods We identified adults with a diagnosis of SMI (schizophrenia, bipolar disorder or ‘other psychosis’) from UK primary care records in Clinical Practice Research Datalink. …”
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The role and contribution of civil society and community actors in COVID-19 prevention and control: the case of the COMVID COVID-19 movement in Burkina Faso
Published 2023-04-01“…These CCVS worked as volunteers, performing door-to-door awareness campaigns. The psychosis created by the pandemic, the proximity of civil society organisations to the communities and the involvement of religious, customary and civil authorities facilitated the expansion of the movement. …”
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249
An intersectional examination of the relationship between racial/ethnic discrimination and psychotic-like experiences: the role of other psychiatric symptoms
Published 2025-01-01“… Abstract Background Racial and ethnic experiences of discrimination (EODs) are associated with numerous psychiatric symptoms, including outcomes along the psychosis spectrum; however, less is known about mechanisms by which EODs confer risk for psychotic-like experiences (PLEs; common subthreshold psychotic symptoms). …”
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READMISSIONS TO ADOLESCENT PSYCHIATRIC INPATIENT CARE: A REGISTER STUDY
Published 2024-11-01“…Additionally, symptoms of psychosis, self-harm and eating disorders increased the risk of readmission. …”
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Associations between mental illness, TB risk and migrant status
Published 2024-12-01“…Sub-analyses highlighted a significant effect of substance use (HR 5.49, 95% CI 4.46–6.76, n < 0.001) and psychosis (HR 4.19, 95% CI 1.74–10.08, n = 0.001) and borderline significance for affective/anxiety/stress-related disorders (HR 1.64, 95% CI 0.98–2.73, n = 0.058) on TB risk. …”
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253
Sex differences in the peripheral levels of cytokines during 12-month antipsychotic treatment in a drug-naïve schizophrenia spectrum cohort
Published 2025-03-01“…Of the 144 enrolled patients with schizophrenia spectrum disorders and ongoing psychosis, 56 were antipsychotic-naïve at baseline (20 women and 36 men) and were included in this study. …”
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General medical comorbidities in psychotic disorders in the Finnish SUPER study
Published 2024-12-01“…The interaction between psychosis, risk factors, and GMCs is complex and should be elucidated. …”
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Evaluation of the Psychiatric Disorders among Amphetamine Addicts in Rehabilitation Centers: A Cross-Sectional Analysis
Published 2024-01-01“…People who are addicted to amphetamines have a much greater chance of developing psychosis compared to those who are not. It is essential to study the behavioral and psychological effects of amphetamines. …”
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Cognitive impairment, depressive and anxiety disorders among post-COVID-19 survivors: a follow-up study
Published 2025-01-01“…For the first year following the SARS disease, they generally suffer from suicide and psychosis. Aim To evaluate the presence of cognitive impairment, anxiety disorders, and depression in adult survivors of COVID-19, 1 month and 3 months post-recovery. …”
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Dutch Validation of the Self-Evaluation of Negative Symptoms Scale (SNS)
Published 2024-12-01“…Methods: The SNS was added to the Pharmacotherapy Monitoring Outcome Survey (PHAMOUS)-protocol for adults with a DSM-5 classification of a disorder in the psychosis spectrum. Internal consistency was assessed by Cronbach’s alpha. …”
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A Mutation in DAOA Modifies the Age of Onset in PSEN1 E280A Alzheimer’s Disease
Published 2016-01-01“…Previous studies have linked polymorphisms in the DAOA gene with the occurrence of neuropsychiatric symptoms such as depression, apathy, aggression, delusions, hallucinations, and psychosis in AD. Our findings strongly suggest that this new conspicuous functional AOO modifier within the G72 (DAOA) gene could be pivotal for understanding the genetic basis of AD.…”
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