Dynamics of blood microsatellite instability (bMSI) burden predicts outcome of a patient treated with immune checkpoint inhibitors: a case report of hyperprogressive disease by Daria Kravchuk, Alexandra Lebedeva, Alexandra Lebedeva, Olesya Kuznetsova, Olesya Kuznetsova, Alexandra Kavun, Anastasiia Taraskina, Ekaterina Belova, Ekaterina Belova, Ekaterina Belova, Tatiana Grigoreva, Tatiana Grigoreva, Egor Veselovsky, Vladislav Mileyko, Vladislav Mileyko, Vladislav Nikulin, Lidia Nekrasova, Alexey Tryakin, Mikhail Fedyanin, Mikhail Fedyanin, Mikhail Fedyanin, Maxim Ivanov, Maxim Ivanov

“…This approach has been proven to be effective in the treatment of patients with MSI-positive colorectal cancer (CRC). …”
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Rapid Identification of Drug-Resistant Tuberculosis Genes Using Direct PCR Amplification and Oxford Nanopore Technology Sequencing by Kaishun Zhao, Chunlin Tu, Wei Chen, Haiying Liang, Wenjing Zhang, Yilei Wang, Ye Jin, Jianrong Hu, Yameng Sun, Jun Xu, Yanfang Yu

“…Gene sequencing technology has proven to be a powerful strategy for identifying relevant drug resistance information. …”
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Shared Bacterial and Viral Respiratory Agents in Bighorn Sheep (Ovis canadensis), Domestic Sheep (Ovis aries), and Goats (Capra hircus) in Montana by David S. Miller, Glen C. Weiser, Keith Aune, Brent Roeder, Mark Atkinson, Neil Anderson, Thomas J. Roffe, Kim A. Keating, Phillip L. Chapman, Cleon Kimberling, Jack Rhyan, P. Ryan Clarke

“…Transmission of infectious agents from livestock reservoirs has been hypothesized to cause respiratory disease outbreaks in bighorn sheep (Ovis canadensis), and land management policies intended to limit this transmission have proven controversial. This cross-sectional study compares the infectious agents present in multiple populations of bighorn sheep near to and distant from their interface with domestic sheep (O. aries) and domestic goat (Capra hircus) and provides critical baseline information needed for interpretations of cross-species transmission risks. …”
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EVALUATION OF ASSISTANCE TOOLS FOR DIAGNOSIS OF DISEASES BY APPROACHING TO PERSONALIZED MEDICINE ON METAGENOMIC DATA by Phan Tấn Tài, Tạ Đặng Vĩnh Phúc, Phan Nguyễn Minh Thảo, Nguyễn Thị Ngọc Chăm, Đào Công Tính, Phạm Huỳnh Ngọc, Nguyễn Thanh Hải

“…The potential advantages of Metagenomic data have been proven through many studies. Within the scope of this research, we introduce and evaluate useful tools for studying Metagenomic data in supporting the diagnosis of human disease and health conditions. …”
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Finerenone in the management of diabetes kidney disease by Parijat De, May T Khine, Andrew Frankel, Gabrielle Goldet, Debasish Banerjee, Rosa M Montero, Tahseen A Chowdhury, Damien Fogarty, Janaka Karalliedde, Ritwika Mallik, Dipesh C Patel, Mona Wahba, Peter Winocour, Sagen Zac-Varghese, Stephen Bain, Adnan Sharif, Srikanth Bellary, Indranil Dasgupta

“…However, emerging therapy such as non-steroidal selective mineralocorticoid antagonists (finerenone) is proven to lower blood pressure and further reduce the risk of progression of DKD and cardiovascular disease in people with type 2 diabetes. …”
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Role of radiological methods of diagnostics at simultaneous pancreas-kidney transplantation by A. V. Pinchuk, I. V. Dmitriev, I. E. Selina, R. Sh. Muslimov, Ye. A. Lapshina, M. V. Parkhomenko, A. S. Kondrashkin

“…Duly diagnostics and the proven choice of miniinvasive techniques for treatment of surgical complications became possible due to wide and urgent application of the whole spectrum of available radiological methods.…”
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Galactomannan in Bronchoalveolar Lavage Fluid for Diagnosis of Invasive Pulmonary Aspergillosis with Nonneutropenic Patients by Qidong Zhuang, Hongying Ma, Yun Zhang, Lei Chen, Li Wang, Lin Zheng, Zaichun Deng, Zhongbo Chen

“…Symptoms and radiological findings had no significant difference between proven or probable IPA group and non-IPA group. In our case-control analysis, although nine patients with false-positive results received treatment with Piperacillin/tazobactam, there was no significant difference between case and control group. …”
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Bridging the gap: community health workers as a vital link in humanitarian medical responses by Cora P. Nally, Patrick Van de Voorde, Marleen Temmerman, Marleen Temmerman, Adama Koroma, Monique Mitchell, Mary B. Adam

“…Community Health Workers (CHWs) have proven essential in improving health outcomes and building community trust and their role in humanitarian emergency medical responses warrants further study. …”
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Role of PPARα and Its Agonist in Renal Diseases by Ching-Feng Cheng, Hsi-Hsien Chen, Heng Lin

“…In clinical application, PPAR-α activators, such as hypolipidemic drugs in fibric acid class, were proven to have therapeutic effects on metabolic syndrome and cardiovascular disease. …”
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Time-Dependent Behavior of Shrinkage Strain for Early Age Concrete Affected by Temperature Variation by Yu Qin, Zhijian Yi, Weina Wang, Di Wang

“…Shrinkage has been proven to be an important property of early age concrete. …”
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Strength and Solidification Mechanism of Silt Solidified by Polyurethane by Fengyuan Li, Chaojie Wang, Yangyang Xia, Yanjie Hao, Peng Zhao, Mingsheng Shi

“…The X-ray diffraction (XRD) and energy-dispersive spectroscopy (EDS) have proven that polyurethane does not react with the silt, but they could improve the strength of the silt through physical action. …”
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Enhancing Plasticity of the Central Nervous System: Drugs, Stem Cell Therapy, and Neuro-Implants by Alice Le Friec, Anne-Sophie Salabert, Carole Davoust, Boris Demain, Christophe Vieu, Laurence Vaysse, Pierre Payoux, Isabelle Loubinoux

“…Biomaterials should ideally resemble lesioned brain structures in architecture and must be proven to increase functional reconnections within host tissue before clinical testing.…”
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The properties improvement of UHPC incorporation cellulose fiber and the autogenous shrinkage reduction mechanism with internal curing effect by Rui Ma, Erheng Wang, Wei Zhang, Daosheng Sun, Yi Ding, Liping Guo

“…Internal curing has been proven to be an efficient way to inhibit shrinkage of ultra-high performance concrete (UHPC). …”
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Triple Hierarchical Variational Inequalities with Constraints of Mixed Equilibria, Variational Inequalities, Convex Minimization, and Hierarchical Fixed Point Problems by Lu-Chuan Ceng, Cheng-Wen Liao, Chin-Tzong Pang, Ching-Feng Wen

“…We introduce and analyze a hybrid iterative algorithm by virtue of Korpelevich's extragradient method, viscosity approximation method, hybrid steepest-descent method, and averaged mapping approach to the gradient-projection algorithm. It is proven that under appropriate assumptions, the proposed algorithm converges strongly to a common element of the fixed point set of infinitely many nonexpansive mappings, the solution set of finitely many generalized mixed equilibrium problems (GMEPs), the solution set of finitely many variational inequality problems (VIPs), the solution set of general system of variational inequalities (GSVI), and the set of minimizers of convex minimization problem (CMP), which is just a unique solution of a triple hierarchical variational inequality (THVI) in a real Hilbert space. …”
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COVID-19 and APOL-1 High-Risk Genotype-Associated Collapsing Glomerulonephritis by Sasmit Roy, Srikanth Kunaparaju, Narayana Murty Koduri, Vikram Sangani, Mytri Pokal, Venu Madhav Konala, Mamtha Balla, Sreedhar Adapa

“…Our case highlights a similar case of COVID-19 in a 65-year-old AA descendant with biopsy-proven FSGS and genetically confirmed APOL-1 alleles.…”
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MUSIC THERAPY: INNOVATIVE STRATEGIES AND SOLUTIONS FOR A MULTIDISCIPLINARY APPROACH TO DESIGN SPACES WITH HIGH ACOUSTIC PERFORMANCES by Diletta Romagnolo, Angelo Bertolazzi, Giorgio Croatto, Eleonora Strada, Umberto Turrini

“…These assessments have proven to be of fundamental importance to ensure an effective dialogue between the different needs of patients and professionals.…”
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The effect of online customer review and online customer rating on the trust and interest of consumer purchases by Purwantoro Purwantoro, Yulfita Aini, Hidayat Hidayat, Arrafiqurrahman Arrafiqurrahman, Andi Afrizal

“…The results obtained from this study are that both reviews and ratings have a proven relationship to customer purchase interest and are an important feature, but not a factor that causes increased customer confidence. …”
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Protein Backbone Torsion Angle-Based Structure Comparison and Secondary Structure Database Web Server by Sunghoon Jung, Se-Eun Bae, Insung Ahn, Hyeon S. Son

“…The reliability of the torsional system, which represents the native processes of structural change in the structural analysis, was partially proven with previous structural alignment studies. …”
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Evaluasi Kinerja MLLIB APACHE SPARK pada Klasifikasi Berita Palsu dalam Bahasa Indonesia by Antonius Angga Kurniawan, Metty Mustikasari

“…The four algorithms were chosen because of their proven ability to classify and several algorithms that are rarely used but have good abilities in terms of classification. …”
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Observer-Based Robust Finite-Time Trajectory Tracking Control for a Stratospheric Satellite Subject to External Disturbance and Actuator Saturation by Shurui Huang, Yueneng Yang, Ye Yan, Shifeng Zhang, Zhiyang Liu

“…Then, a stability analysis using Lyapunov-based theory is performed, in which the stabilization of the stratospheric satellite system and finite-time convergence are proven. Furthermore, a number of simulations are conducted further to verify the excellent performance of the designed control strategy.…”
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