Stage-specific function of sphingolipid synthases in African trypanosomes by Norton Heise, Carolina M. Koeller, Mohamed Sharif, James D. Bangs

“…ABSTRACT The protozoan parasite Trypanosoma brucei is the only known eukaryote capable of synthesizing the three main phosphosphingolipids: sphingomyelin (SM), inositol phosphorylceramide (IPC), and ethanolamine phosphorylceramide (EPC). …”
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Prevalence of Toxoplasma gondii, Neospora caninum, and Sarcocystis Species DNA in the Heart and Breast Muscles of Rock Pigeons (Columbia livia) by Muhammad Mudasser Nazir, Muhammad Mazhar Ayaz, Atif Nisar Ahmed, Azhar Maqbool, Kamran Ashraf, Muhammad Oneeb, Ghulam Yasin, Atta Subhani, Muhammad Asif Ali, Noman Nazir, Muhammad Afzal Sajid

“…Little is known about the prevalence of protozoan parasites in the muscles of rock pigeons (Columbia livia). …”
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Risk factors for Toxoplasma gondii seropositivity in buffaloes in a Mediterranean area by Giovanna Cappelli, Antonio Bosco, Alessandra Martucciello, Gabriele Di Vuolo, Domenico Vecchio, Carlo Grassi, Maria Serrapica, Michele Napoletano, Paola Pepe

“… Toxoplasmosis is a worldwide widespread zoonotic infection caused by the intracellular protozoan Toxoplasma gondii. This infection is considered one of the most important food-borne parasitic zoonoses globally. …”
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Prevalence and associated factors of intestinal parasitic infections in the Badi indigenous communities of Western Nepal by Jitendra Gautam, Rajendra Prasad Parajuli, Kishor Pandey

“…The study revealed an overall parasite prevalence of 27% (n = 55) in the indigenous Badi communities. Protozoan infections were found in 19% (n = 39) of the studied community, whereas helminthic infections were present in only 7.8% (n = 16). …”
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In Vitro Mechanism of Action of Acanthospermum hispidum in Trypanosoma brucei by Aboagye Kwarteng Dofuor, Temitayo Samson Ademolue, Karen Nana Akua Kuampah, Frederick Ayertey, Theresa Manful Gwira

“…This study aimed to investigate the cellular mechanisms of antitrypanosomal and antioxidant activities of A. hispidum against Trypanosoma brucei (T. brucei), a causative protozoan species of African trypanosomiasis. Fractions were prepared from the whole plant of A. hispidum through solvent partitioning by employing solvents of varying polarities (hexane, HEX; dichloromethane, DCM; ethyl acetate, EA; aqueous, AQ). …”
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A short ncRNA modulates gene expression and affects stress response and parasite differentiation in Leishmania braziliensis by José C. Quilles, Caroline R. Espada, Lissur A. Orsine, Tânia A. Defina, Letícia Almeida, Fabíola Holetz, Angela K. Cruz

“…The protozoan parasite Leishmania spp. is a causative agent of leishmaniasis, a disease that affects millions of people in more than 80 countries worldwide. …”
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Synthesis and evaluation of nitrochromene derivatives as potential antileishmanial therapeutics through biological and computational studies by Niloofar Javid, Ali Asadipour, Ehsan Salarkia, Mohammad Amin Langarizadeh, Fatemeh Sharifi, Mohammad Mahdavi, Bagher Amirheidari, Aida Iraji, Hojjat Rezaiezadeh, Gholamreza Hassanpour, Yaghoub Pourshojaei

“…Abstract Leishmaniasis is a parasitic disease caused by protozoan organisms belonging to the Leishmania genus, affecting many individuals worldwide, with the burden surpassing one million cases. …”
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First Report on the Frequency and Subtype Distribution of <i>Blastocystis</i> sp. in Extensively Reared Holstein-Friesian Cattle from Terceira Island, Azores Archipelago, Portugal by Sara Gomes-Gonçalves, Alexandra Silva, Guilherme Moreira, Nausicaa Gantois, Rubén Garcia Dominguez, Eric Viscogliosi, Magali Chabé, João R. Mesquita

“…<i>Blastocystis</i> sp. is an enteric protozoan with high genetic diversity and is associated with both zoonotic and non-zoonotic subtypes (STs). …”
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Reorganization of Extracellular Matrix in Placentas from Women with Asymptomatic Chagas Disease: Mechanism of Parasite Invasion or Local Placental Defense? by Juan Duaso, Erika Yanez, Christian Castillo, Norbel Galanti, Gonzalo Cabrera, Gabriela Corral, Juan Diego Maya, Inés Zulantay, Werner Apt, Ulrike Kemmerling

“…Chagas disease, produced by the protozoan Trypanosoma cruzi (T. cruzi), is one of the most frequent endemic diseases in Latin America. …”
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Infections with Giardia duodenalis and Entamoeba histolytica/Entamoeba dispar as Hidden and Prevalent Conditions in Periurban Communities in the State of Rio de Janeiro, Brazil by Deiviane A. Calegar, Kerla J. L. Monteiro, Andressa B. Gonçalves, Márcio N. Boia, Lauren H. Jaeger, Beatriz C. Nunes, Filipe A. Carvalho-Costa

“…Laboratory diagnosis of protozoan enteric infections and effective drugs for their treatment are unmet goals in the primary health care system. …”
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Genotoxicity Revaluation of Three Commercial Nitroheterocyclic Drugs: Nifurtimox, Benznidazole, and Metronidazole by Annamaria Buschini, Lisa Ferrarini, Susanna Franzoni, Serena Galati, Mirca Lazzaretti, Francesca Mussi, Cristina Northfleet de Albuquerque, Tânia Maria Araújo Domingues Zucchi, Paola Poli

“…Nitroheterocyclic compounds are widely used as therapeutic agents against a variety of protozoan and bacterial infections. However, the literature on these compounds, suspected of being carcinogens, is widely controversial. …”
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Fatal toxoplasmic encephalitis triggered by anti-TNF therapy by Rodrigo A. Montoro, Michael Moran, Katherine A. Overmyer, Andrew Periaccante, Joshua J. Coon, Swapnil Lanjewar, Laura J. Knoll, Rob Striker

“…Reactivation of a latent infection by the protozoan parasite Toxoplasma gondii can result in severe neurologic outcomes and even death. …”
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Knowledge, attitudes, and practices toward leishmaniasis and one health: a cross-sectional study among medical and veterinary professionals by Yasir Khan, I-Chen Lin, Sundus Khan, Mehtab Kanwal, Abdul Wajid, Aamir Khan, Fazal Noor, Ali Madi Almajwal, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Chien-Chin Chen, Abdul Qadeer

“…Knowledge about leishmaniasis was high, with 97.5% of participants recognizing Leishmania and 86% correctly identifying it as a protozoan disease. The majority (71.8%) believed in the zoonotic transmission of Leishmania from animals to humans. …”
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Transcriptional profiles analysis of effects of Toxoplasma gondii rhoptry protein 16 on THP-1 macrophages by Ningai Yang, Ningai Yang, Ningai Yang, Mingyang Li, Hong Yang, Jiaming Li, Tiantian Dang, Guangqi Li, Zhijun Zhao, Zhijun Zhao, Zhijun Zhao

“…IntroductionToxoplasma gondii, an intracellular parasitic protozoan, is globally recognized for its ability to cause parasitic diseases and has developed diverse strategies to evade immune-mediated elimination. …”
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Coproantigen detection and molecular identification of Cryptosporidium species among newborn and adult farm animals by Dina Aboelsoued, Nagwa I. Toaleb, Kadria N. Abdel Megeed

“…Abstract Cryptosporidium sp. is an obligatory intracellular apicomplexan protozoan parasite that causes a disease called cryptosporidiosis with substantial veterinary and medical importance. …”
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A murine model of Trypanosoma brucei-induced myocarditis and cardiac dysfunction by Nathan P. Crilly, Marcelle Dina Zita, Alexander K. Beaver, Polina Sysa-Shah, Aashik Bhalodia, Kathy Gabrielson, Luigi Adamo, Monica R. Mugnier

“…ABSTRACT Trypanosoma brucei is a protozoan parasite that causes human and animal African trypanosomiases (HAT and AAT). …”
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Frequency of Trypanosoma cruzi Infection in Synanthropic and Wild Rodents Captured in a Rural Community in Southeast of Mexico by Ivonne Hernández-Cortazar, Karla Cecilia Amaya Guardia, Marco Torres-Castro, Karla Acosta-Viana, Eugenia Guzmán-Marín, José Israel Chan-Pérez, Antonio Ortega-Pacheco, Roger I. Rodríguez-Vivas, Rodrigo Medina-Pinto, Matilde Jiménez-Coello

“…The protozoan parasite Trypanosoma cruzi is the causative agent of the Chagas disease, which is endemic in southeastern Mexico and is transmitted by the vector Triatoma dimidiata (triatomide). …”
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Molecular and Clinical Characterization of Giardia duodenalis Infection in Preschool Children from Lisbon, Portugal by Filipa Santana Ferreira, Rita Alexandre dos Santos Soares de Bellegarde Machado Sá da Bandeira, Cláudia Alexandra Cecílio de Sampaio Ferreira Constantino, Ana Maria Teixeira Duarte Cancela da Fonseca, Joana da Graça Matias Gomes, Rúben Miguel Lopes Rodrigues, Jorge Luís Marques da Silva Atouguia, Sónia Chavarria Alves Ferreira Centeno-Lima

“…Giardia duodenalis is the most prevalent intestinal protozoan infection especially in children. In Portugal scarce data are available relative to this infection in preschoolers. …”
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Antiplasmodial and Cytotoxic Activities of Extracts of Selected Medicinal Plants Used to Treat Malaria in Embu County, Kenya by Bibianne Waiganjo, Gervason Moriasi, Jared Onyancha, Nelson Elias, Francis Muregi

“…Malaria is a deadly disease caused by a protozoan parasite whose mode of transmission is through a female Anopheles mosquito. …”
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Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei by Samhita Das, Tanaya Unhale, Carine Marinach, Belsy del Carmen Valeriano Alegria, Camille Roux, Hélène Madry, Badreddine Mohand Oumoussa, Rogerio Amino, Shiroh Iwanaga, Sylvie Briquet, Olivier Silvie

“…Abstract Malaria is caused by protozoan parasites of the genus Plasmodium and remains a global health concern. …”
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