Cryptic transmission of a SARS-CoV-2 variant detected by wastewater surveillance in Panama by Melissa Gaitán, Yamitzel Zaldivar, Michelle Hernandez, Jessica Góndola, Oris Chavarría, Brechla Moreno, Danilo Franco, Rodrigo DeAntonio, Santiago Mirazo, Florencia Cancela, Maria Eugenia Barnett, Alexander A. Martinez, Juan Miguel Pascale, Sandra López-Vergès

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Neuron-Specific Glycine Metabolism Links Transfer RNA Epitranscriptomic Regulation to Complex Behaviors by Jennifer Blaze, Viviana Dolores Evans, Jessica Abigail Feria Pliego, Petr Unichenko, Behnam Javidfar, Soeren Heissel, Hanan Alwaseem, Zachary Pennington, Denise Cai, Henrik Molina, Christian Henneberger, Schahram Akbarian

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Salivary Protein Profile and Food Intake: A Dietary Pattern Analysis by Teresa Louro, Carla Simões, Wilmara Lima, Laura Carreira, Paula Midori Castelo, Henrique Luis, Pedro Moreira, Elsa Lamy

“…Our results support the association of salivary proteomics and different dietary patterns and highlight the need of considering food consumption habits in studies using saliva, since this is a factor associated with variations in the composition of this fluid.…”
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Activity of Various Cathepsin Proteases and Enrichment of Klotho Protein in the Urine and Urinary Extracellular Vesicles After SARS-CoV-2 Infection by Niharika Bala, Ramish H. Rafay, Sarah C. Glover, Abdel A. Alli

“…Urinary extracellular vesicles (uEVs) were isolated from urine samples from the two groups and used for proteomic analysis and subsequent pathway analyses. …”
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The effect of resveratrol on the cryopreservation of Mongolian horse semen by M. Du, M. Du, M. Du, Y. Liu, Y. Liu, Y. Liu, L. Zhang, L. Zhang, L. Zhang, X. Li, X. Li, X. Li, N. Wang, N. Wang, N. Wang, Q. He, Q. He, Q. He, J. Cao, J. Cao, J. Cao, B. Zhao, B. Zhao, B. Zhao, Y. Shi, Y. Shi, Y. Shi, B. Li, B. Li, B. Li, G. Bou, G. Bou, G. Bou, M. Dugarjaviin, M. Dugarjaviin, M. Dugarjaviin

“…The study also employed tandem mass tag (TMT) quantitative proteomics technology to explore differential proteins and their pathways. …”
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EMC2 suppresses ferroptosis via regulating TFRC in nasopharyngeal carcinoma by Xianghui Chen, Xiaoyan Wang, Yuxia Zou, Yan Wang, Tingting Duan, Zijie Zhou, Yi Huang, Qing Ye

“…Method: We conducted quantitative proteomics to detect dysregulated proteins in NPC tissues. …”
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Anaerobic metabolism promotes breast cancer survival via Histone-3 Lysine-18 lactylation mediating PPARD axis by Ying Xu, Weiwei Meng, Yingqi Dai, Lin Xu, Ning Ding, Jinqing Zhang, Xuewei Zhuang

“…Additionally, we confirmed that HDAC2 and HDAC3 act as “erasers” for H3 lysine lactylation. During the proteomics analysis, AKT-phosphorylation in the aerobic respiration inhibitor group exhibited an apparent disparity and activity. …”
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Acquired vulnerability against EGF receptor inhibition in gastric cancer promoted by class I histone deacetylase inhibitor entinostat by Tamara Zenz, Robert Jenke, Denys Oliinyk, Sandra Noske, René Thieme, Tim Kahl, Ines Gockel, Florian Meier-Rosar, Achim Aigner, Thomas RH Büch

“…Based on these results, a combined entinostat plus EGFR inhibitor erlotinib treatment in vitro and in vivo was studied. Results: Proteomics analyses in gastric cancer cells treated with entinostat revealed a marked upregulation of EGFR in the majority of cell lines and an even more robust induction of the EGFR ligand AREG. …”
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The developmental lipidome of Nippostrongylus brasiliensis by Tao Wang, Michael G. Leeming, Nicholas A. Williamson, Tiffany Bouchery, Rory Doolan, Graham Le Gros, Gavin E. Reid, Nicola L. Harris, Robin B. Gasser

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Fungal genomes: suffering with functional annotation errors by Tapan Kumar Mohanta, Ahmed Al-Harrasi

“…Results An analysis of proteome sequence data of 689 fungal species (7.15 million protein sequences) was conducted to identify the presence of functional annotation errors. …”
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Wavenumber-dependent transmission of subthreshold waves on electrical synapses network model of Caenorhabditis elegans by Iksoo Chang, Taegon Chung, Sangyeol Kim

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Properties of Actinobacillus pleuropneumoniae isolates by V. А. Evgrafova, О. V. Pruntova, N. B. Shadrova, А. М. Timina

“…Results of tests of six Actinobacillus pleuropneumoniae isolates recovered from the diseased pigs kept in animal holdings located in the Russian Federation for their biological properties (biochemical, proteomic, antigenic and pathogenic ones) are presented in the paper. …”
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Identification of KIFC1 as an independent prognostic marker in renal clear cell carcinoma correlates with tumor proliferation and immune infiltration by Bin Du, Jia Wang, Jinping Zheng, Jing Huo, Pu Wang

“…We analyzed the prognostic value, associated signaling pathways, and regulatory mechanisms of KIFC1 in ccRCC through bioinformatics and proteomics. Concretely, both mRNA and protein expression levels of KIFC1 were dramatically upregulated. …”
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Microbial signatures in head and neck squamous cell carcinoma: an in silico study by Loganathan KAVITHA, Manogaran KUZHALMOZHI, Jayaseelan VIJAYASHREE PRIYADHARSINI, Arunachalam ARUN KUMAR, Krishna Mohan Rao UMADEVI, Kannan RANGANATHAN

“…Methodology The microbe-host transcriptomic, proteomic, and epigenetic analyses of HNSCC and GI carcinomas were performed using The Cancer Microbiome Atlas (TCMA) database. …”
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Corrigendum to “Depletion of ß1,6-N-acetylglucosaminyltransferase reduces E-selectin binding capacity and migratory potential of human gastrointestinal adenocarcinoma cells” [Neopl... by Lisa Staffeldt, Hanna Maar, Julia Beimdiek, Samuel Chambers, Kristoffer Riecken, Mark von Itzstein, Falk FR Buettner, Arun Everest-Dass, Tobias Lange

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Profiling endogenous airway proteases and antiproteases and modeling proteolytic activation of Influenza HA using in vitro and ex vivo human airway surface liquid samples. by Stephanie A Brocke, Boris Reidel, Camille Ehre, Meghan E Rebuli, Carole Robinette, Kevin D Schichlein, Christian A Brooks, Ilona Jaspers

“…The airway proteolytic environment likely contains redundant antiproteases and proteases with diverse catalytic mechanisms, however a proteomic profile of these enzymes and inhibitors in airway samples has not been reported. …”
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Increased cardiac myosin super-relaxation as an energy saving mechanism in hibernating grizzly bears by Robbert J. Van der Pijl, Weikang Ma, Christopher T.A. Lewis, Line Haar, Amalie Buhl, Gerrie P. Farman, Marcus Rhodehamel, Vivek P. Jani, O Lynne Nelson, Chengxin Zhang, Henk Granzier, Julien Ochala

“…Methods: Thin cardiac strips were isolated from the left ventricles of active and hibernating grizzly bears; and subjected to loaded Mant-ATP chase assays, X-ray diffraction and proteomics. Main findings: Hibernating grizzly bears displayed an unusually high proportion of ATP-conserving super-relaxed cardiac myosin molecules that are likely due to altered levels of phosphorylation and rod region stability. …”
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A Molecular, Genetic, and Diagnostic Spotlight on Fanconi Anemia by Laura E. Hays, Stefan Meyer, Henri J. van de Vrugt

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Exosomes derived from syncytia induced by SARS-2-S promote the proliferation and metastasis of hepatocellular carcinoma cells by Huilong Li, Huilong Li, Haotian Lin, Haotian Lin, Tinghui Fan, Linfei Huang, Li Zhou, Xiaoyu Tian, Ruzhou Zhao, Yanhong Zhang, Xiaopan Yang, Luming Wan, Hui Zhong, Nan Jiang, Congwen Wei, Wei Chen, Wei Chen, Lihua Hou, Lihua Hou

“…Differentially expressed proteins in syncytia-derived exosomes (Syn-Exos) and their functions was analyzed by Proteomic sequencing. Syn-Exo-mediated promotion of hepatocellular carcinoma cells was measured by CCK-8 and Transwell migration assays. …”
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Mitochondrial dysfunction-driven AMPK-p53 axis activation underpins the anti-hepatocellular carcinoma effects of sulfane sulfur by Xue Zheng, Yuhua Luo, Rui Huo, Yiwen Wang, Youbang Chen, Mianrong Chen, Qi Zhao, Kexin Li, Hanyi Zhang, Xiaotong Li, Xiang Li, Hui Zhang, Zaopeng He, Li Huang, Chun-tao Yang

“…We utilized bioinformatics algorithms for clustering, function enrichment, feature screening and survival analysis on proteomic data from the Cancer Proteome Atlas (CPTAC) and transcriptomic data from the Cancer Genome Atlas (TCGA). …”
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