YgaE Regulates Out Membrane Proteins in Salmonella enterica Serovar Typhi under Hyperosmotic Stress by Min Wang, Ping Feng, Xun Chen, Haifang Zhang, Bin Ni, Xiaofang Xie, Hong Du

“…Two-dimensional electrophoresis was applied to analyze proteomics of total proteins in wild-type strain and ΔygaE strain and we found that YgaE represses the expression of OmpA at the late stage of hyperosmotic stress. …”
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Role of Eukaryotic Initiation Factors during Cellular Stress and Cancer Progression by Divya Khandige Sharma, Kamiko Bressler, Harshil Patel, Nirujah Balasingam, Nehal Thakor

“…Extensive evidence shows that the transcriptome and corresponding proteome do not invariably correlate with each other in a variety of contexts. …”
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Unveiling unique effector function-related bulk antibody profiles in long-term hemodialysis patients following COVID-19 mRNA booster vaccination by Chia-Yi Chou, Chung-Yi Cheng, Chih-Hsin Lee, Makoto Kuro-O, Tso-Hsiao Chen, San-Yuan Wang, Yung-Kun Chuang, Yun-Jung Yang, Yun-Hsuan Lin, I-Lin Tsai

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Integrative computational analysis of anti-influenza potential in Caesalpinia mimosoides Lamk hydroethanolic extract by Anuwatchakij Klamrak, Shaikh Shahinur Rahman, Napapuch Nopkuesuk, Jaran Nabnueangsap, Jaraspim Narkpuk, Piyapon Janpan, Yutthakan Saengkun, Thananya Soonkum, Supawadee Sriburin, Samaporn Teeravechyan, Poramet Sitthiwong, Nisachon Jangpromma, Sirinan Kulchat, Kiattawee Choowongkomon, Rina Patramanon, Arunrat Chaveerach, Jureerut Daduang, Sakda Daduang

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Characterizing the omics landscape based on 10,000+ datasets by Eva Brombacher, Oliver Schilling, Clemens Kreutz

“…In this study, we investigate over ten thousand datasets to understand how proteomics, metabolomics, lipidomics, transcriptomics, and microbiome data vary in specific data characteristics. …”
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Disorders in brassinosteroids signal transduction triggers the profound molecular alterations in the crown tissue of barley under drought. by Anetta Kuczyńska, Martyna Michałek, Piotr Ogrodowicz, Michał Kempa, Paweł Krajewski, Vladimiro Cardenia, Maria Teresa Rodriguez-Estrada, Marina Pérez-Llorca, Sergi Munné-Bosch, Krzysztof Mikołajczak

“…Large-scale transcriptomic and proteomic profiling confirmed the specific re-modeling of behavior of the BRs-insensitive barley uzu1.a mutant under drought. …”
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Minimally invasive determination of pancreatic ductal adenocarcinoma (PDAC) subtype by means of circulating cell‐free RNA by Martin Metzenmacher, Gregor Zaun, Marija Trajkovic‐Arsic, Phyllis Cheung, Timm M. Reissig, Hendrik Schürmann, Nils vonNeuhoff, Grainne O'Kane, Stephanie Ramotar, Anna Dodd, Steven Gallinger, Alexander Muckenhuber, Jennifer J. Knox, Volker Kunzmann, Peter A. Horn, Jörg D. Hoheisel, Jens T. Siveke, Smiths S. Lueong

“…We used whole transcriptome sequencing of 10 plasma samples with tumor‐informed subtypes, complemented by proteomic analysis for minimally invasive identification of PDAC subtype markers. …”
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Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction by Andrew C. Hiday, Michael C. Edler, Asma B. Salek, Cameron W. Morris, Morrent Thang, Tyler J. Rentz, Kristie L. Rose, Lisa M. Jones, Anthony J. Baucum

“…Spinophilin association with PP1 is increased concurrent with decreases in PP1 activity in an animal model of PD. Using proteomic-based approaches, we observed dopamine depletion-induced decreases in spinophilin binding to multiple protein classes in the striatum. …”
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Application of Metabolomics in Thyroid Cancer Research by Anna Wojakowska, Mykola Chekan, Piotr Widlak, Monika Pietrowska

“…Beside genomics, transcriptomics, and proteomics, metabolomic approach emerges as the most downstream attitude reflecting phenotypic changes and alterations in pathophysiological states of biological systems. …”
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High Throughput Approaches to Unravel the Mechanism of Action of a New Vanadium-Based Compound against Trypanosoma cruzi by M. Florencia Mosquillo, Pablo Smircich, Analía Lima, Sergio A. Gehrke, Gonzalo Scalese, Ignacio Machado, Dinorah Gambino, Beatriz Garat, Leticia Pérez-Díaz

“…Concordantly, no drastic changes of the parasite transcriptome were detected after 6 h of treatment. Instead, proteomic analysis uncovered the modulation of proteins involved in different processes such as energy and redox metabolism, transport systems, detoxifying pathways, ribosomal protein synthesis, and proteasome protein degradation. …”
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Antibody Responses and the Vaccine Efficacy of Recombinant Glycosyltransferase and Nicastrin Against <i>Schistosoma japonicum</i> by Bowen Dong, Haoran Zhong, Danlin Zhu, Luobin Wu, Jinming Wang, Hao Li, Yamei Jin

“…While praziquantel remains the primary treatment, concerns about drug resistance highlight the urgent need for new drugs and effective vaccines to achieve sustainable control. Previous proteomic studies from our group revealed that the expression of <i>Schistosoma japonicum</i> glycosyltransferase and nicastrin as proteins was higher in single-sex males than mated males, suggesting their critical roles in parasite reproduction and their potential as vaccine candidates. …”
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Protein Glycation in Diabetes as Determined by Mass Spectrometry by Annunziata Lapolla, Laura Molin, Pietro Traldi

“…The development of mass spectrometric techniques able to give highly specific and reliable results in proteome field is of wide interest for physicians, giving them new tools to monitor the disease progression and the possible complications related to diabetes, as well as the effectiveness of therapeutic treatments. …”
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Zika virus modulates human fibroblasts to enhance transmission success in a controlled lab-setting by Raimondas Mozūraitis, Karsten Cirksena, Mohammad Raftari, Melika Hajkazemian, Musa Mustapha Abiodun, Juela Brahimi, Sandra Radžiutė, Violeta Apšegaitė, Rasa Bernotienė, Lech Ignatowicz, Tessy Hick, Andreas Kirschning, Annasara Lenman, Gisa Gerold, S. Noushin Emami

“…The findings are complemented by an extensive meta-proteome analysis. Overall, we demonstrate a multifaceted role of virus-host interaction and shed light on how arboviruses may influence the behaviour of their vectors as an evolved means of improving transmission-success.…”
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Cross-trait multivariate GWAS confirms health implications of pubertal timing by Siquan Zhou, Yujie Xu, Jingyuan Xiong, Guo Cheng

“…We find 266 independent variants in 197 loci, including 18 novel variants. Transcriptomic, proteome imputation and fine-mapping analyses reveal genes causal for pubertal timing, including KDM4C, LEPR, CCNC, ACP1, and PCSK1. …”
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Isolation of Viral Biofilms From HTLV-1 Chronically Infected T Cells and Integrity Analysis by Coline Arone, Hélène Dutartre, Delphine Muriaux

“…In this study, we optimized a protocol to isolate HTLV-1 biofilms from chronically infected T cells, facilitating their structural and molecular characterization using proteomic and super-resolution microscopy analyses. …”
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Integrative multi-omics analysis reveals the translational landscape of the plant-parasitic nematode Meloidogyne incognita by Zhaolu Zhu, Dexin Bo, Chuanshuai Xie, Dadong Dai, Donghai Peng, Ming Sun, Jinshui Zheng

“…In this study, we elucidated the translational landscape of Meloidogyne incognita through the integration of translatome, transcriptome and quantitative proteome analyses. Our findings revealed numerous previously unannotated translation events and refined the genome annotation. …”
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An Innovative Method to Identify Autoantigens Expressed on the Endothelial Cell Surface: Serological Identification System for Autoantigens Using a Retroviral Vector and Flow Cytom... by Tsuyoshi Shirai, Hiroshi Fujii, Masao Ono, Ryu Watanabe, Tomonori Ishii, Hideo Harigae

“…For identification of autoantigens, proteomics and expression library analyses have been performed for many years with some success. …”
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Sex-specific response of intramuscular fat to diet-induced obesity in rats by Hannah E. Smith, Nada Abughazaleh, Ruth A. Seerattan, Faizan Syed, Daniel Young, Antoine Dufour, David A. Hart, Raylene A. Reimer, Walter Herzog

“…Using a combination of histological staining techniques, quantitative proteomics, and measures of metabolic syndrome and inflammation, it was determined that the diet-induced obesity model in female Sprague-Dawley rats is a viable model with pronounced effects on the musculoskeletal system. …”
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Characterizing the Contaminant-Adhesion of a Dibenzofuran Degrader <i>Rhodococcus</i> sp. by Yu Chen, Qingquan Wei, Xudi Wang, Yanan Wu, Changai Fu, Xu Wang, Hangzhou Xu, Li Li

“…Compared with sodium acetate as a carbon source, the percentages of glucose and proteins related to electron transfer, toxin–antitoxin, and stress responses were elevated, which were analyzed by polysaccharide composition and proteomics, and the contents of extracellular polysaccharides and proteins were increased. …”
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Evidence for Activation of Toll-Like Receptor and Receptor for Advanced Glycation End Products in Preterm Birth by Taketoshi Noguchi, Toshiyuki Sado, Katsuhiko Naruse, Hiroshi Shigetomi, Akira Onogi, Shoji Haruta, Ryuji Kawaguchi, Akira Nagai, Yasuhito Tanase, Shozo Yoshida, Takashi Kitanaka, Hidekazu Oi, Hiroshi Kobayashi

“…A systematic search was performed in the electronic databases PubMed and ScienceDirect up to July 2010, combining the keywords “preterm birth,” “TLR”, “RAGE”, “danger signal”, “alarmin”, “genomewide,” “microarray,” and “proteomics” with specific expression profiles of genes and proteins. …”
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