Quantitative proteomics and targeted metabolomics reveal the role of Cassia siamea L. extract in the response to high-fat diet-induced obesity in Drosophila by Ananya Dechakhamphu, Nattapong Wongchum, Theeraphan Chumroenphat, Alongklod Tanomtong, Sirithon Siriamornpun

“…Moreover, this study investigated the effects of the extract combined with a high-fat diet on amino acid metabolism and proteomic profiles to clarify its mechanism of action. …”
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Proteomic Identification of Heat Shock-Induced Danger Signals in a Melanoma Cell Lysate Used in Dendritic Cell-Based Cancer Immunotherapy by Fermín E. González, Alexey Chernobrovkin, Cristián Pereda, Tamara García-Salum, Andrés Tittarelli, Mercedes N. López, Flavio Salazar-Onfray, Roman A. Zubarev

“…Here, we characterized the proteomic profile of TRIMEL in response to HS treatment. …”
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Quantitative proteomic analysis unveils a critical role of VARS1 in hepatocellular carcinoma aggressiveness through the modulation of MAGI1 expression by Natalia Hermán-Sánchez, Mercedes del Rio-Moreno, Rubén Ciria, Marina E. Sánchez-Frias, Maite G. Fernández-Barrena, Iker Uriarte, Eduardo Chicano-Galvez, Ignacio Ortea, Ángela Peralbo-Molina, Javier Briceño, Matías A. Avila, Manuel Rodríguez-Perálvarez, Raúl M. Luque, Juan L. López-Cánovas, Manuel D. Gahete

Subjects: “…Quantitative proteomics…”
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Design of a Multiepitope Pan-Proteomic mRNA Vaccine Construct Against African Swine Fever Virus: A Reverse Vaccinology Approach by Ella Mae Joy S. Sira, Lauren Emily Fajardo, Edward C. Banico, Nyzar Mabeth O. Odchimar, Fredmoore L. Orosco

“…In this study, a reverse vaccinology approach was used to design a multiepitope pan-proteomic mRNA vaccine against ASFV. Various bioinformatics tools were employed to predict epitopes for cytotoxic T lymphocytes, helper T lymphocytes, and B lymphocytes. …”
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Chemo-proteomics reveals dihydrocaffeic acid exhibits anti-inflammation effects via Transaldolase 1 mediated PERK-NF-κB pathway by Guanjun Li, Huiying Li, Peili Wang, Xinzhou Zhang, Wenhua Kuang, Ling Huang, Ying Zhang, Wei Xiao, Qingfeng Du, Huan Tang, Jigang Wang

Subjects: “…Activity-based chemical proteomic…”
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Identification of Proteins with Potential Osteogenic Activity Present in the Water-Soluble Matrix Proteins from Crassostrea gigas Nacre Using a Proteomic Approach by Daniel V. Oliveira, Tomé S. Silva, Odete D. Cordeiro, Sofia I. Cavaco, Dina C. Simes

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Galectin-1-Dependent Mitochondria Apoptosis Plays an Essential Role in the Potential Protein Targets of DBDCT-Induced Hepatotoxicity as Revealed by Quantitative Proteomic Analyses by Jiayu Song, Yuan Ren, Lihua Liu, Yixin Wang, Chuandao Shi, Xiaoqing Ji, Yunlan Li, Qingshan Li

“…However, the effective targets and mechanisms for specific toxicity and biological activity are still unclear. In this study, proteomic analysis revealed that 146 proteins (98 upregulated and 48 downregulated) were differentially identified by label-free LC-MS/MS after DBDCT treatment. …”
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Interconnections between BDH1-plasma protein-type 2 diabetes Mellitus: a mediated mendelian randomization analysis using plasma proteomics by Yi-Ying Liu, Yue-Yang Zhang, Qin Wan

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Tandem mass tag-based quantitative proteomics and targeted hormone analysis reveal the response to insect herbivory stress in Ginseng (Panax ginseng, L.). by Haitao Li, Lixin Zhang, Xiang Han, Qi Zhang, Guangna Liu, Guofeng Zhang, Yurong Zhu, Hongyang Liu, Haowei Deng, Shuangli Liu, Guangsheng Xi

“…The results showed that ginsenosides present in the stems and leaves were more responsive to insect herbivory treatment than those present in the roots. Through proteomics, we found that the expression of most of the differentially expressed proteins, including GAPC1, GAPC2, and CSD1, was downregulated by insect herbivory treatment, HSP81-3 expression was up-regulated under insect herbivory stress. …”
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A proteomic analysis identifies higher AHSG (Alpha-2-HS-glycoprotein) in saliva of oropharyngeal cancer patients – A potential salivary biomarker by Anu Jain, Aafaque Ahmad Khan, Rajandeep Kaur, Roshan K Verma, Jaimanti Bakshi, Aditi Chatterjee, Amanjit Bal, Sushmita Ghoshal, Arnab Pal

“…This study was designed to identify a potential salivary biomarker for OPC using proteomics approach. Materials and methods: OPC cases were enrolled in different cohorts depending on the tobacco consumption habits as smokers, chewers, smokers and chewers and no tobacco consumers. …”
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Protocol to identify endogenous proximal proteins using biotinylation by antibody recognition by Camilla Rega, Mercedes Pardo, Lesley-Ann Martin, Jyoti Choudhary

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Advances in Serological Diagnosis of Neurocysticercosis in Korea by Chun-Seob Ahn, Jeong-Geun Kim, Sun Huh, Insug Kang, Yoon Kong

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Sex similarities and differences in the reverse and anti-remodeling effect of pressure unloading therapy in a rat model of aortic banding and debanding by Tímea Bálint, Mihály Ruppert, Bálint András Barta, Korkmaz-Icöz Sevil, Loganathan Sivakkanan, Attila Oláh, Sayour Alex Ali, Kálmán Benke, Dávid Nagy, Karck Matthias, Oliver Schilling, Béla Merkely, Gábor Szabó

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iTRAQ-Based Proteomic Analysis of Visual Cycle-Associated Proteins in RPE of rd12 Mice before and after RPE65 Gene Delivery by Qinxiang Zheng, Yueping Ren, Radouil Tzekov, Shanshan Hua, Minghan Li, Jijing Pang, Jia Qu, Wensheng Li

“…To investigate the iTRAQ-based proteomic changes of visual cycle-associated proteins in RPE of rd12 mice before and after RPE65 gene delivery. …”
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Combining extracellular matrix proteome and phosphoproteome of chickpea and meta‐analysis reveal novel proteoforms and evolutionary significance of clade‐specific wall‐associated events in plant by Kanika Narula, Arunima Sinha, Pooja Choudhary, Sudip Ghosh, Eman Elagamey, Archana Sharma, Atreyee Sengupta, Niranjan Chakraborty, Subhra Chakraborty

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Blood proteomics and multimodal risk profiling of human volunteers after incision injury: A translational study for advancing personalized pain management after surgery by Daniel Segelcke, Julia R. Sondermann, Christin Kappert, Bruno Pradier, Dennis Görlich, Manfred Fobker, Jan Vollert, Peter K. Zahn, Manuela Schmidt, Esther M. Pogatzki-Zahn

Subjects: “…Blood plasma proteomics…”
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The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity. by Liam C Hunt, Michelle Curley, Kudzai Nyamkondiwa, Anna Stephan, Jianqin Jiao, Kanisha Kavdia, Vishwajeeth R Pagala, Junmin Peng, Fabio Demontis

“…Interestingly, UBE2D/eff knockdown in young age reproduces part of the proteomic changes that normally occur in old muscles, suggesting that the decrease in UBE2D/eff protein levels that occurs with aging contributes to reshaping the composition of the muscle proteome. …”
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Protein and metabolite acclimations to temperature variability in a calcareous green macroalga Halimeda macroloba by Hao Zhang, Yuyu Wang, Lingshuai Zhang, Zhiqin Wang, Zejun Zhu, Lijuan Long, Lijuan Long

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Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface by Bianca A. Lepe, Christine R. Zheng, Owen K. Leddy, Benjamin L. Allsup, Sydney L. Solomon, Bryan D. Bryson

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Accelerated aging modulates the toxicological properties of the diazo tattoo pigment PO13 by Lise Aubry, Marianne Vitipon, Aurélie Hirschler, Hélène Diemer, Thierry Rabilloud, Christine Carapito, Thierry Douki

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