LC/MS/MS Analysis of N-Terminal Protein Adducts with Improved Sensitivity: A Comparison of Selected Edman Isothiocyanate Reagents by Per Rydberg, Hans von Stedingk, Jörgen Magnér, Jonas Björklund

“…The principles of the FIRE-procedure are that adducts to N-terminal amino acids selectively are detached and measured from of proteins after derivatisation by isothiocyanate Edman reagents. …”
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Suggestive Diagnostic Process in a Case of Multiple Myeloma with Gastrointestinal Immunoglobulin Light-Chain Amyloidosis Accompanied by Protein-Losing Enteropathy by Katsuya Endo, Takehito Ito, Jun Nomura, Keigo Murakami, Shiho Kondo, Tomonori Satoh, Daisuke Fukushi, Yuki Yoshino, Yoshiteru Sasaki, Atsuko Takasu, Takayuki Kogure, Morihisa Hirota, Takayoshi Meguro, Kazuhiro Murakami, Junichi Kameoka, Kennichi Satoh

“…We report a case of an 80-year-old man with multiple myeloma accompanied by gastrointestinal AL amyloidosis and secondary protein-losing enteropathy. The diagnostic process was suggestive, in that diarrhea and refractory leg edema related to protein-losing enteropathy were the primary symptoms and the trigger for making a sequential diagnosis of gastrointestinal AL amyloidosis and underlying multiple myeloma. …”
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Prediction and verification of the influence of the rs367781716 SN P on the interaction of ТАТА -binding protein with the promoter of the human АВСА9 gene by O. V. Arkova, I. A. Drachkova, T. V. Arshinova, D. A. Rasskazov, V. V. Suslov, P. M. Ponomarenko, M. P. Ponomarenko, N. A. Kolchanov, L. K. Savinkova

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Estimation of D-dimer, C-reactive protein and ferritin in Covid-19 survivors in a North Indian Hospital, Lucknow, India. by Chetna Singla, Dhananjay Tiwari, Himali Jha, Mohammad Mustufa Khan, Sadaf Parveen, Roshan Alam

Subjects: “…C-reactive protein…”
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Chronic Kidney Disease Stage Is a Modulator on the Association between High-Sensitivity C-Reactive Protein and Coronary Vasospastic Angina by Heng-Jung Hsu, Chiung-Hui Yen, Kuang-Hung Hsu, I-Wen Wu, Chin-Chan Lee, Chiao-Yin Sun, Chia-Chi Chou, Chun-Yu Chen, Shih-Ying Yang, Chi-Jen Tsai, Mai-Szu Wu, Ming-Jui Hung

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SARS-CoV-2 ORF3a accessory protein is a water-permeable channel that induces lysosome swelling by Antonio Michelucci, Luigi Sforna, Riccardo Focaia, Maria Vittoria Leonardi, Angela Di Battista, Giorgia Rastelli, Simone Vespa, Simona Boncompagni, Manlio Di Cristina, Luigi Catacuzzeno

“…Abstract ORF3a, the most abundantly expressed accessory protein of SARS-CoV-2, plays an essential role in virus egress by inactivating lysosomes through their deacidification. …”
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High interstitial fluid pressure enhances USP1-dependent KIF11 protein stability to promote hepatocellular carcinoma progression by Zhengyi Wu, Chao Li, Shouhua Zhang, Liang Sun, Junwen Hu, Bingbing Qiu, Shuiqiu Liu, Yiran Hong, Tianxiang Chen, Kai Wang, Xiangbao Yin, Jinlong Yan

“…Inhibition of USP1 using ML323 significantly reduced KIF11 protein levels and suppressed tumor progression in the mouse model. …”
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VdPAT1 encoding a pantothenate transporter protein is required for fungal growth, mycelial penetration and pathogenicity of Verticillium dahliae by Stephen Mwangi Kamau, Yongtai Li, Tiange Sun, Feng Liu, Qian-Hao Zhu, Xinyu Zhang, Jie Sun, Yanjun Li

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Effects of adding silver carp Hypophthalmichthys molitrix protein concentrate on sensory, texture and cooking properties of pasta and its shelf life by Mahsasadat Mousavi Sane, Seyedeh Zahra Mirhosseini Roudbaraki, Mohammad Ali Nematollahi, Seyed Vali Hosseini

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4-1BB agonist targeted to fibroblast activation protein α synergizes with radiotherapy to treat murine breast tumor models by Ignacio Melero, Alvaro Teijeira, Christian Klein, Maria E Rodriguez-Ruiz, Christina Claus, Pablo Umana, Tamara Tanos, Carlos E De Andrea, Carlos Luri-Rey, Paloma Sanchez-Mateos, Leticia Fernández-Rubio, María Collantes, Irantzu Serrano-Mendioroz, Celia Barrio-Alonso, Antonio Rullan, Jon Ander Simon, Eneko Garate-Soraluze, Claudia del Pilar Herrero

“…Fibroblast activation protein (FAP) is expressed on the surface of cancer-associated fibroblasts (CAF) in many cancer types and its abundance is associated with the poor immune response to immune-checkpoint-blockade in patients. …”
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Integrating machine learning and structure-based approaches for repurposing potent tyrosine protein kinase Src inhibitors to treat inflammatory disorders by Muhammad Waleed Iqbal, Muhammad Shahab, Zakir ullah, Guojun Zheng, Irfan Anjum, Gamal A. Shazly, Atrsaw Asrat Mengistie, Xinxiao Sun, Qipeng Yuan

“…Abstract Tyrosine-protein kinase Src plays a key role in cell proliferation and growth under favorable conditions, but its overexpression and genetic mutations can lead to the progression of various inflammatory diseases. …”
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Genome-Wide Identification and Analysis of the Cytochrome B5 Protein Family in Chinese Cabbage (Brassica rapa L. ssp. Pekinensis) by Han Zheng, Xin Li, Lin Shi, Ying Jing, Qingqing Song, Yanan Chen, Lilong He, Fengde Wang, Jianwei Gao, Yuping Bi

“…Protein interaction analysis showed that 40 interaction patterns were predicted including two Sucrose Transporter 4 subfamily proteins (SUT 4) and Fatty Acid Hydroxylase 2 protein (FAH 2) can interact with most members of BrCB5s. …”
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Pilocarpine-Induced Status Epilepticus Is Associated with Changes in the Actin-Modulating Protein Synaptopodin and Alterations in Long-Term Potentiation in the Mouse Hippocampus by Maximilian Lenz, Marina Ben Shimon, Thomas Deller, Andreas Vlachos, Nicola Maggio

“…Here, we addressed the question of whether pilocarpine-induced status epilepticus affects synaptopodin (SP), an actin-binding protein, which regulates the ability of neurons to express synaptic plasticity. …”
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Polyphenol-Protein Complexes and Their Consequences for the Redox Activity, Structure and Function of Honey. A Current View and New Hypothesis – a Review by Brudzynski Katrina, Maldonado-Alvarez Liset

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Impact of protein intake from a caloric-restricted diet on liver lipid metabolism in overweight and obese rats of different sexes by Ying Tian, Jiawei Gong, Zhiyan He, Suwen Peng, Yuping Huan, Hongpeng Cao

Subjects: “…Protein intake…”
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The identification of a SARs-CoV2 S2 protein derived peptide with super-antigen-like stimulatory properties on T-cells by Thai Hien Tu, Fatima Ezzahra Bennani, Nasser Masroori, Chen Liu, Atena Nemati, Nicholas Rozza, Amichai Meir Grunbaum, Richard Kremer, Catalin Milhalcioiu, Denis-Claude Roy, Christopher E. Rudd

“…An outstanding question is whether SARS-CoV-2 protein sequences can directly induce inflammatory responses. …”
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Comparative diagnostic performance of recombinant Tams1 protein based dot-ELISA in detecting tropical theileriosis in naturally infected cattle by Sanjhi Paliwal, Vikrant Sudan, Daya Shanker

“…The recombinant Tams1 protein was successfully cloned and expressed using a pET-30b (+) expression vector in a prokaryotic system. …”
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Low-Protein Diet Supplemented with Keto Acids Is Associated with Suppression of Small-Solute Peritoneal Transport Rate in Peritoneal Dialysis Patients by Na Jiang, Jiaqi Qian, Aiwu Lin, Wei Fang, Weiming Zhang, Liou Cao, Qin Wang, Zhaohui Ni, Qiang Yao

“…We investigate whether low-protein diet would show benefits in suppressing peritoneal transport rate in peritoneal dialysis (PD) patients. …”
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Effects of Bariatric Surgeries on Fetuin-A, Selenoprotein P, Angiopoietin-Like Protein 6, and Fibroblast Growth Factor 21 Concentration by Jakub Poloczek, Wojciech Kazura, Ewa Kwaśnicka, Janusz Gumprecht, Jerzy Jochem, Dominika Stygar

“…In these patients, the most effective procedure is bariatric surgery, but it is still difficult to predict its outcome and metabolic changes. Hepatokines are proteins secreted by hepatocytes. Many of them, including fetuin-A, selenoprotein P, angiopoietin-like protein 6, and fibroblast growth factor 21, have been linked to metabolic dysfunctions. …”
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CRISPR-Based Programmable Nucleic Acid-Binding Protein Technology Can Specifically Detect Fatal Tropical Disease-Causing Pathogens by Md. Rashidur Rahman, Toma Rani Majumder, Md. Aminul Islam Apu, Alok K. Paul, Afrina Afrose, Biplab Kumar Dash

“…It consists of CRISPR-associated proteins (Cas) capable of targeting virtually any specific RNA or DNA genome based on the guide RNA (gRNA) sequence. …”
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