Effects of Bacillus subtilis-fermented soybean meal replacing fish meal on antioxidant activity, immunity, endoplasmic reticulum stress and hepatopancreas histology in Pacific whit... by Songming Chen, Jieyu Dai, Yan Chen, Qiang Chen, Fen Dong, Congcong Wang, Yulong Sun, Jiteng Wang, Tao Han

“…In summary, this study indicated that when the fish meal content account for 40% in diets (dry weight), the screened Bacillus subtilis-FSBM can replace 25% of fish meal protein without reducing the antioxidant and immune abilities of shrimp.…”
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Seroprevalence of Foot and Mouth Disease Virus Infection in Some Wildlife and Cattle in Bauchi State, Nigeria by Y. J. Atuman, C. A. Kudi, P. A. Abdu, O. O. Okubanjo, A. Abubakar, Y. Wungak, H. G. Ularamu

“…Out of the 353 sera collected from cattle and wildlife 197 (65.7%) and 13 (24.5%) (P<0.05), respectively, tested positive for antibodies to the highly conserved nonstructural 3ABC protein of FMDV by the FMDV-NS blocking ELISA. Classification of cattle into breed and sex showed that detectable antibodies to FMDV were higher (P<0.05) in White Fulani 157 (72.8%) than in Red Bororo 23 (39.7%) and Sokoto Gudali 17 (33.3%) breeds of cattle, whereas in females, detectable FMDV antibodies were higher (P<0.05) 150 (72.8%) than in males 47 (50.0%). …”
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Nutrient density and the collaborative impact of exogenous enzyme blend on the performance of broiler chicken by Jun Young Mun, Habeeb Tajudeen, Sang Hun Ha, Jun Hyung Lee, Anushka Lokhande, Santosh Laxman Ingale, Jin Soo Kim, Min Ju Kim

“…The diets included a control (CON) starter/finisher (S/F) diet with metabolizable energy (ME) 3,100/3,200 in Kcal/kg and crude protein (CP) content 22.0.0/20.00 in % as (S/F 3,100/3,200 Kcal/kg + CP [22.00/20.00]%), S/F with ME 3,060/3,150 Kcal/kg + CP (21.50/19.50)% with and without the exogenous enzyme blend as (S/F 3,060/3,150 Kcal/kg + [21.50/19.50]% with, and without the exogenous enzyme blend), and lastly, S/F with ME 3,010/3,100 Kcal/kg + CP (21.50/19.50)% with, and without the exogenous enzyme blend as (S/F 3,010/3,100 Kcal/kg + [21.50/19.50]% with, and without the exogenous enzyme blend). …”
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A noninvasive method for the detection of foetal DNA in early pregnancy based on differential methylation pattern of Ras association domain family member 1A by Yulin Sha, Wei Liu, Jiongzhi Hong, Yan Yang, Jian Yu, Xiaodong Fu

“…Immunofluorescence techniques targeting histocompatibility complex, class I G (HLA-G) and GATA binding protein 3 (GATA-3) were employed to detect EVTs in the cell samples and in decidual tissue, with the latter providing an additional layer of confirmation for the presence of foetal cells.Results The results showed no hypermethylated RASSF1A was detected in any of the cervical samples, irrespective of whether the samples were obtained by brush or lavage. …”
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Chickens productivity selection affects immune system genes by А. М. Borodin, Ya. I. Alekseev, K. E. Gerasimov, N. V. Konovalova, E. V. Тerentjeva, D. N. Efimov, Zh. V. Emanuilova, L. I. Tuchemskiy, A. A. Komarov, V. I. Fisinin

“…This suggests that these genes experience selection pressure. Analysis of the protein-coding sequences of the CD1B and DMA genes of various breeds of chickens revealed a negative selection of these genes. …”
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Intravenous immunoglobulin for mortality and inflammatory status in patients with sepsis: a retrospective database study by Hayabusa Takano, Hayabusa Takano, Naoki Kanda, Naoki Kanda, Yuji Wakimoto, Hiroyuki Ohbe, Kensuke Nakamura, Kensuke Nakamura

“…Primary outcomes were 28-day mortality, while secondary outcomes included in-hospital mortality, the Barthel Index at discharge, length of hospital stay and laboratory data (albumin, C-reactive protein (CRP), and lymphocyte count) on days 14 and 28.ResultsOf the 17,626 patients enrolled, 15,159 (786 in the IVIG group and 14,373 in the control group) were included in the analysis. …”
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Interactive effects of triploidy induction and culture densities on growth performance and stress, immune, and metabolic responses in juvenile rainbow trout (Oncorhynchus mykiss) by Roghayeh Mahmoudi, Mahdi Naderi, Hakimeh Dopeikar, Seyed Ali Khorasaninasab, Seyed Hadi Seyedalhosseini

“…After 9 weeks, final weight, weight gain, specific growth rate, and protein efficiency ratio (PER) in fish cultured at 20, 30, and 40 kg/m3 were significantly higher and feed conversion ratio (FCR) was lower compared to those cultured at 50 kg/m3 (P < 0.05). …”
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FBR2 modulates ferroptosis via the SIRT3/p53 pathway to ameliorate pulmonary fibrosis by Yu Cheng, Yang Jiao, Wan Wei, Mengjia Kou, Yaodong Cai, Yang Li, Hao Li, Tonghua Liu

“…Assessments encompassed histopathology, ELISA for cytokine detection, IHC and Western blot for protein expression analysis, and qRT-PCR for gene expression quantification. …”
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Efficacy and Safety of Recombinant Human Thrombopoietin (rhTPO) on Coagulation Function and Inflammatory Factors in the Treatment of Patients with Sepsis-Related Thrombocytopenia by Huijuan Wang MD, Dong Chen MD, Ming He MD

“…Coagulation function indicators, including activated partial thromboplastin time (APTT), fibrinogen (FIB), plasminogen activator inhibitor-1 (PAI-1), antithrombin III (AT-III), protein C, thrombomodulin (TM), and Plt factor 4 (PF4), showed greater improvement in the Group R compared to the Group C ( P  < 0.05). …”
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Affecting of Glyphosate Tolerance and Metabolite Content in Transgenic <i>Arabidopsis thaliana</i> Overexpressing <i>EPSPS</i> Gene from <i>Eleusine indica</i> by Jingchao Chen, Zhiling Li, Haiyan Yu, Hailan Cui, Xiangju Li

“…The results showed that the average resistance index of the transgenic lines was 4.7 and the exogenous <i>E. indica EPSPS</i> expression levels were 265.3- to 532.0-fold higher than those in the wild-type (WT) line. The EPSPS protein ranged from 148.5 to 286.2 μg g⁻¹, which was substantially higher than that in the WT line (9.1 μg g⁻¹). 103 metabolites associated with flavone and flavonol biosynthesis, the metabolism of aromatic amino acids, energy metabolism, and auxin synthesis were significantly higher in the transgenic glyphosate-resistant individuals (R) than in the WT individuals. …”
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Urinary NGAL and RBP Are Biomarkers of Normoalbuminuric Renal Insufficiency in Type 2 Diabetes Mellitus by Aimei Li, Bin Yi, Yan Liu, Jianwen Wang, Qing Dai, Yuxi Huang, Yan Chun Li, Hao Zhang

“…Levels of urinary neutrophil gelatinase-associated lipocalin (NGAL), retinol-binding protein (RBP), plasminogen activator inhibitor-1 (PAI-1), vascular cell adhesion molecule-1 (VCAM-1), and E-cadherin were detected, and their correlations with eGFR, plasma TNF-α, IL-6, endothelin-1 (ET-1), and 8-hydroxydeoxyguanosine (8-OHdG) were assessed. …”
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Genome polymorphism of the synthetic species xTrititrigia cziczinii Tsvel. inferred from AFLP analysis by A. A. Trifonova, K. V. Boris, L. V. Dedova, V. A. Melnik, L. P. Ivanova, N. P. Kuzmina, S. V. Zavgorodniy, V. P. Upelniek

“…×T. cziczinii has unique characteristics, as it is a perennial species, with the ability to grow after mowing, high adaptability, resistance to diseases and pests, high protein and gluten content in the grain. All this makes it a promising new crop for agriculture. …”
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The efficacy and safety of induction chemotherapy combined with sintilimab followed by concurrent chemoradiotherapy plus sintilimab sequencing maintaining with sintilimab for patie... by Ruifeng Wang, Tianhui Guo, Qi Wang, Wen Gao, Yimiao Yu, Jun Zhang, Wenqian Fu, Haiji Wang, Biyuan Zhang

“…Abstract Purpose To evaluate the efficacy and safety of induction chemotherapy combined with programmed death protein 1 (PD-1) inhibitor (sintilimab) followed by concurrent chemoradiotherapy (CCRT) plus sintilimab, and subsequent maintenance with sintilimab (IC-ICCRT-IO) for patients with unresectable locally advanced esophageal squamous cell carcinoma (ESCC) in a retrospective study. …”
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Plastid genome comparison and phylogenetic analyses of the Chinese group of medicinal species and related taxa within Asparagus genus by Pingxuan Xie, Tinglu Wang, Jiawei Tan, Linyuan Fan, Changkun Liu, Hanjing Yan

“…However, accurate authentication of these medicinal species and their phylogenetic relationships with related taxa remains unresolved.MethodsTo identify simple sequence repeats (SSRs) and divergence hotspot regions appropriate for future authentication studies, as well as to infer the phylogenetic relationships among Asparagus species, we employed a plastid genome (plastome) dataset consisting of 25 Asparagus species (21 newly sequenced and four retrieved from GenBank), encompassing 12 Chinese medicinal species, for comparative and phylogenetic analyses.ResultsAll Asparagus plastomes displayed a typical quadripartite structure with sizes ranging from 155,948 bp to 157,128 bp and harbored 114 unique genes (80 protein-coding genes, 30 tRNA genes, and four rRNA genes). …”
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A novel approach to regulate glucose uptake in an anaplastic thyroid cancer cell line by Shabnam Heydarzadeh, Ali Asghar Moshtaghie, Maryam Daneshpour, Mehdi Hedayati

“…Determination of GLUT1 and GLUT3 mRNA and protein expression in SW1736 cells was performed by qRT-PCR and western blotting. …”
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Clinical and Immunological Characteristics of Elderly Onset Rheumatoid Arthritis by LI Zhengfang, WU Chanyuan, MA Mengsi, LI Tingting, WU Xue, MENG Xinyan, ZHANG Sha, WU Lijun

“…Greater inflammation [C-reactive protein(CRP) : 12.3(3.9, 33.2)mg/L vs. 5.5(1.8, 16.9)mg/L, P=0.000; erythrocyte sedimentation rate(ESR) : 30.5(15.0, 63.0)mm/h vs. 19.0(8.0, 41.0)mm/h, P= 0.006], higher DAS28-CRP score [4.0(2.7, 5.0) vs. 3.2(2.4, 4.9), P=0.002] and DAS28-ESR score [4.3 (2.8, 5.3) vs. 3.4 (2.1, 4.7), P=0.001] were also observed. …”
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Probiotic administration aggravates dextran sulfate sodium salt-induced inflammation and intestinal epithelium disruption in weaned pig by Kunhong Xie, Weidong Cai, Lingjie Li, Bing Yu, Yuheng Luo, Zhiqing Huang, Xiangbing Mao, Jie Yu, Ping Zheng, Hui Yan, Hua Li, Jun He

“…Results Presence of A. muciniphila in DSS-challenged weaned pigs resulted in numerically increased diarrhea rate, blood neutrophilic granulocyte, serum C-reactive protein and immunoglobulin M levels, and numerically reduced final weight, average daily feed intake and average daily gain. …”
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Evaluation and Management of Patients with Hematoma After Gynecologic and Obstetric Surgery by Bekir Kahveci, Mehmet Obut, Serhat Ege, Mete Sucu, Nurullah Peker, Osman Uzundere, Gaye Kahveci, Mehmet Sukru Budak

“…Incidence of hematoma account for 0.2%. The mean c-reactive protein was 37.9±47.4 mg/dL at admission and 14.6±25.8 mg/dL at discharge, respectively. …”
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Evaluation of two-dimensional ultrasound fetal thymus size in correlation to infection parameters in pregnancies complicated with preterm premature rupture of membranes by Amal Kotb Abdallah, Mohamed Mohesen, Nagwan Kamal, Sahar Mahmoud Abd Elsalam, Sondos Salem, Ehab Salama, Mazen Abdel-Rasheed, Mohamed Eweis

“…The primary outcome of the study was to measure fetal thymus size by abdominal ultrasound and its correlation with maternal total leukocytic count (TLC) and its differential count, C-reactive protein (CRP), and maternal fever. The secondary outcomes involved the correlation of the fetal thymus size with fetal distress, the occurrence of neonatal infection, Apgar neonatal score, and histological examination of the placenta and membranes for evidence of chorioamnionitis. …”
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tiRNA-Gln-CTG is Involved in the Regulation of Trophoblast Cell Function in Pre-eclampsia and Serves as a Potent Biomarker by Yixiao Wang, Xiaohong Ji, Hengmei Shi, Sicong Liu, Hong Yu

“…Extracellular vesicle (EV) carriers may mediate the level of tiRNA-Gln-CTG in the circulation. Y-box binding protein-1 (YBX1) may be involved in loading tiRNA-Gln-CTG into EVs. …”
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