Showing 1,361 - 1,380 results of 15,527 for search '"proteins"', query time: 0.12s Refine Results
  1. 1361

    Multifaceted functions of the Wilms tumor 1 protein: From its expression in various malignancies to targeted therapy by Qing Nian, Yan Lin, Jinhao Zeng, Yanna Zhang, Rongxing Liu

    Published 2025-02-01
    “…Wilms tumor 1 (WT1) is a multifaceted protein with dual functions, acting both as a tumor suppressor and as a transcriptional activator of oncogenes. …”
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    Structural studies of the IFNλ4 receptor complex using cryoEM enabled by protein engineering by William S. Grubbe, Bixia Zhang, Aileen Kauffman, Fabian Byléhn, Kasia Padoł, Hae-Gwang Jung, Seung Bum Park, Jessica M. Priest, Engin Özkan, Juan J. de Pablo, T. Jake Liang, Minglei Zhao, Juan L. Mendoza

    Published 2025-01-01
    “…Further, we perform a structural analysis using molecular modeling and simulation to identify a unique region of IFNλ4 that, when replaced, enables secretion of the protein from cells. These findings provide a structural and functional understanding of the IFNλ4 protein and enable future comprehensive studies towards correcting IFNλ4 dysfunction in large populations of affected patients.…”
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  8. 1368

    The Relationship between C-Reactive Protein/Albumin Ratio and Disease Activity in Patients with Inflammatory Bowel Disease by Yi-Han Chen, Li Wang, Shu-Yi Feng, Wei-Min Cai, Xiao-Fu Chen, Zhi-Ming Huang

    Published 2020-01-01
    “…The aims of this study were to evaluate the C-reactive protein/albumin ratio (CRP/ALB), inflammatory markers, and parameters from the complete blood count (CBC) in patients with inflammatory bowel disease (IBD) and their associations with disease activity. …”
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    Genome-wide association data reveal a global map of genetic interactions among protein complexes. by Gregory Hannum, Rohith Srivas, Aude Guénolé, Haico van Attikum, Nevan J Krogan, Richard M Karp, Trey Ideker

    Published 2009-12-01
    “…Here, we present an integrative approach that greatly increases power through marker clustering and projection of marker interactions within and across protein complexes. Applied to a recent gene association study in yeast, this approach identifies 2,023 genetic interactions which map to 208 functional interactions among protein complexes. …”
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  12. 1372

    Elevation of High-Mobility Group Protein Box-1 in Serum Correlates with Severity of Acute Intracerebral Hemorrhage by Yu Zhou, Kun-Lin Xiong, Sen Lin, Qi Zhong, Feng-Lin Lu, Hong Liang, Jing-Cheng Li, Jing-Zhou Wang, Qing-Wu Yang

    Published 2010-01-01
    “…High-mobility group protein box-1 (HMGB1) is a proinflammatory involved in many inflammatory diseases. …”
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  16. 1376

    The Prognostic Impact of Protein Expression of E-Cadherin-Catenin Complexes Differs between Rectal and Colon Carcinoma by Rolf Aamodt, Johan Bondi, Solveig Norheim Andersen, Arne Bakka, Geir Bukholm, Ida R. K. Bukholm

    Published 2010-01-01
    “…There were statistically significant differences in protein expression between the rectal and the colon carcinomas regarding membranous 𝛽-catenin, 𝛾-catenin, p120-catenin, and E-cadherin, as well as nuclear 𝛽-catenin. …”
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    Cereblon: A Protein Crucial to the Multiple Functions of Immunomodulatory Drugs as well as Cell Metabolism and Disease Generation by Qinglin Shi, Lijuan Chen

    Published 2017-01-01
    “…It is well known that cereblon is a key protein in autosomal recessive nonsyndromic mental retardation. …”
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