Enzymic Activity, Metabolites, and Hematological Responses Changes of Clinical Healthy High-Risk Beef Calves During Their First 56-Days from Arrival by Octavio Carrillo-Muro, Pedro Hernández-Briano, Paola Isaira Correa-Aguado, Alejandro Rivera-Villegas, Oliver Yaotzin Sánchez-Barbosa, Rosalba Lazalde-Cruz, Alberto Barreras, Alejandro Plascencia, Daniel Rodríguez-Cordero

“…The enzymatic activity and metabolites analyzed were alkaline phosphatase (ALP), gamma glutamyltransferase (GGT), aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein (TP), albumin (ALB), globulin (GLO), ALB/GLO ratio, blood urea nitrogen (BUN), creatinine (CRE), total bilirubin (TBIL), total cholesterol (TCHO), triglycerides (TG); (4) calcium (Ca), glucose (GLU), sodium (Na⁺), potassium (K⁺), and chlorine (Cl⁻). …”
Get full text

Exploring the effect of feeding broiler chickens a diet incorporating unfermented or fermented palm kernel cake: growth performance, digestibility, biochemical indices, digestive e... by Sindaye Daniel, Shehata Zeid, Liao Jinghong, Suqin Hang

“…Fermented PKC, particularly LPKC, improved the broiler chicken’s digestibility of crude protein, gross energy, crude fiber, lactase, and trypsin enzyme activities compared to the control group (p < 0.05). …”
Get full text

Lentivirus‐mediated gene therapy for Fabry disease: 5‐year End‐of‐Study results from the Canadian FACTs trial by Aneal Khan, Dwayne L. Barber, William M. McKillop, C. Anthony Rupar, Christiane Auray‐Blais, Graeme Fraser, Daniel H. Fowler, Alexandra Berger, Ronan Foley, Armand Keating, Michael L. West, Jeffrey A. Medin

“…Body weight, blood pressure, urinary protein levels, eGFR, troponin levels, and LVMI were tracked. …”
Get full text

Real-World Evidence of Clinical Outcomes of the Use of the Adalimumab Biosimilar SB5 in Rheumatic and Gastrointestinal Immune-Mediated Inflammatory Diseases: 12-Month Data from the... by Bruno Fautrel, Yoram Bouhnik, Carine Salliot, Franck Carbonnel, Mathurin Fumery, Christophe Bernardeau, Yves Maugars, Mathurin Flamant, Fabienne Coury, Ben Braithwaite, Salima Hateb, Janet Addison, the PERFUSE investigators

“…Clinical data, including disease activity scores, C-reactive protein levels, and dosing information, were collected as available from patient records captured during routine visits to specialist physicians. …”
Get full text

Features of expression of immunohistochemical markers in local and generalized clear cell kidney cancer by E. M. Frantsiyants, A. N. Shevchenko, E. A. Dzhenkova, N. S. Karnaukhov, T. A. Gudtskova, A. A. Breus, E. V. Filatova, D. A. Shvyrev

“…In generalized kidney cancer, epithelial-mesenchymal transformation processes are more pronounced in comparison with local cancer (a significant increase in Vimentin expression by 28% and CD44 by 16.6% (P&lt;0.05), a decrease in E‑cadherin expression by 24% (P&lt;0.05), and activation of neoangiogenesis processes (a significant increase in VEGF expression by 32%, P&lt;0.05). The P53 protein was absent in local kidney cancer cells and was extremely low when generalized – 3.8±0.7%. …”
Get full text

Enhancing reproductive capacity in hybrid Red Tilapia (Oreochromis niloticus ×‎ O. mossambicus) via dietary administration of date palm pollen (Phoenix dactylifera L.)‎ by Nashi K. Alqahtani, Hesham S. Ghazzawy, Roshmon Thomas Mathew, Yousef‎ Ahmed Alkhamis, Rashid Saleh Alngada, Moaheda E.H. Eissa, Sameh A. Abdelnour, Sara F. Ghanem, Layla A. Almutairi, El-Sayed Hemdan Eissa

“…The results demonstrated that fish fed diets supplemented with 20 g or 40 g of DPP exhibited significantly higher levels of total protein, albumin, and globulin compared to the control group (P < 0.01). …”
Get full text

Associations between milk infrared-predicted plasma biomarkers of stress resilience and fertility in dairy cattle: Insights for enhancing breeding programs and herd management by Alessio Cecchinato, Hugo Toledo-Alvarado, Lucio Flavio Macedo Mota, Vittoria Bisutti, Erminio Trevisi, Riccardo Negrini, Sara Pegolo, Stefano Schiavon, Luigi Gallo, Giovanni Bittante, Diana Giannuzzi

“…Specifically, increasing levels of ceruloplasmin, total reactive oxygen metabolites, and advanced oxidation protein products resulted in a relevant decrease in the HR of cows becoming pregnant. …”
Get full text

Bone Marrow Mesenchymal Stem Cells-Derived Exosomes Inhibit Apoptosis of Pulmonary Microvascular Endothelial Cells in COPD Mice Through miR-30b/Wnt5a Pathway by Song Q, Zhou A, Cheng W, Zhao Y, Liu C, Zeng Y, Lin L, Zhou Z, Peng Y, Chen P

“…The knockdown of miR-30b in BMSCs-derived exosomes could increase the apoptosis of CSE-induced PMVECs (p< 0.05). miR-30b overexpression significantly reduced apoptosis and repressed Wnt5a protein expression in CSE-induced PMVECs (p< 0.05). …”
Get full text

LGR4 is essential for maintaining β-cell homeostasis through suppression of RANK by Joanna Filipowska, Zelda Cisneros, Sneha S. Varghese, Nancy Leon-Rivera, Peng Wang, Randy Kang, Geming Lu, Yate-Ching Yuan, Hung-Ping Shih, Supriyo Bhattacharya, Sangeeta Dhawan, Adolfo Garcia-Ocaña, Nagesha Guthalu Kondegowda, Rupangi C. Vasavada

“…The Leucine-rich repeat-containing G-protein-coupled receptor (GPCR) 4 (LGR4) is expressed in β-cells and is the fourth most abundant GPCR in human islets. …”
Get full text

Anti-Inflammatory Potential and Synergic Activities of <i>Eclipta prostrata</i> (L.) L. Leaf-Derived Ointment Formulation in Combination with the Non-Steroidal Anti-Inflammatory Dr... by Muhammad M. Poyil, Mohammed H. Karrar Alsharif, Mahmoud H. El-Bidawy, Salman Bin Dayel, Mohammed Sarosh Khan, Zainab Mohammed M. Omar, Alaaeldin Ahmed Mohamed, Reda M. Fayyad, Tarig Gasim Mohamed Alarabi, Hesham A. Khairy, Nasraddin Othman Bahakim, Mohamed A. Samhan, Abd El-Lateef Saeed Abd El-Lateef

“…The phytochemical analysis of the <i>E. prostrata</i> extract showed the presence of various phytochemicals, including flavonoids, Tannin, saponin, terpenoids, glycosides, phenol, alkaloids, quinone, and protein. The GC-MS profiling of methanolic <i>E. prostrata</i> extract was performed predicted the presence of twenty important phytochemicals, including 2-[5-(2-Hydroxypropyl) oxolan-2-yl]propanoic acid, dl-Menthol, dodecane, undecane, 4,7-dimethyl-, dodecane, 2,6,10-trimethyl-, decane, 2,3,5,8-tetramethyl-, cholest-5-en-3-ol, (3.alpha.)-, TMS derivative, cyclopropane carboxylic acid, 1-hydroxy-, (2,6-di-t-butyl-4-methylphenyl) ester, alpha.…”
Get full text

Biosynthesis inhibition of miR-142-5p in a N 6-methyladenosine-dependent manner induces neuropathic pain through CDK5/TRPV1 signaling by Jinshi Li, Yang Guo, Chen Zhu, Dongxu Wang, Yuan Li, Xiaotong Hao, Linyan Cao, Yiting Fan, Bo Fang

“…Western blot analysis was employed to determine changes in protein expression for TRPV1 and CDK5. For assessing the interaction mechanism and binding site between TRPV1 and CDK5, various techniques were applied, including mass spectrometry, coimmunoprecipitation (co-IP), and glutathione-S-transferase (GST)-pulldown assays. …”
Get full text

Randomised trial of coconut oil, olive oil or butter on blood lipids and other cardiovascular risk factors in healthy men and women by Stephen J Sharp, Kay-Tee Khaw, Robert Luben, Nita G Forouhi, Leila Finikarides, Islam Afzal, Marleen Lentjes

“…Of these, 91 men and women attended a follow-up assessment 4 weeks later.Intervention Participants were randomised to extra virgin coconut oil, extra virgin olive oil or unsalted butter and asked to consume 50 g daily of one of these fats for 4 weeks, which they could incorporate into their usual diet or consume as a supplement.Main outcomes and measures The primary outcome was change in serum LDL-C; secondary outcomes were change in total and high-density lipoprotein cholesterol (TC and HDL-C), TC/HDL-C ratio and non-HDL-C; change in weight, body mass index (BMI), waist circumference, per cent body fat, systolic and diastolic blood pressure, fasting plasma glucose and C reactive protein.Results LDL-C concentrations were significantly increased on butter compared with coconut oil (+0.42, 95% CI 0.19 to 0.65 mmol/L, P&lt;0.0001) and with olive oil (+0.38, 95% CI 0.16 to 0.60 mmol/L, P&lt;0.0001), with no differences in change of LDL-C in coconut oil compared with olive oil (−0.04, 95% CI −0.27 to 0.19 mmol/L, P=0.74). …”
Get full text

Effect of Simultaneous Use of Different Amounts of Biochar and Soil Application of Common Sulfur and Spraying of Nanosulfur on Yield and Yield Components and Some Phytochemical Cha... by Vahid Mohammadzadeh Kakhki, mohmmad Hossein Aminifard, Mohamad Behzad Amiri

“…Its deficiency can significantly hinder nitrogen metabolism, as sulfur and nitrogen are required to form amino acids essential for protein synthesis. Sulfur is also present in fatty acids and vitamins, playing a key role in crops' quality, taste, and aroma. …”
Get full text

A Study on the Yield and Related Traits of some Forage Low-Tannin Faba bean (Vicia faba L.) Genotypes by Hamidreza Ghorbani, Mohamad Taghi Feyzbakhsh

“…Extended Abstract Background: The faba bean (Vicia faba L.) is considered one of the important legumes and is cultivated as a source of cheap protein. This plant is very suitable for agriculture due to having suitable agricultural characteristics, including nitrogen fixation and the possibility of being placed in crop rotation with fall crops, especially cereals. …”
Get full text

Interplay between oxidative stress, neuroinflammatory cytokines and melatonin in Alzheimer's disease: Insights from cerebrospinal fluid analysis by Francisco Artime-Naveda, David Hevia, Rebeca Alonso-Arias, Carmen Martínez, Isabel Quirós-González, Rafael Cernuda-Cernuda, Alejando Alvarez-Artime, Iván Menéndez-Valle, Rosa M. Sainz, Juan C. Mayo

“…CSF levels of Aβ, T-tau and P-tau were assayed, and patients were further classified according to threshold CSF levels of the three markers protein following the criteria of NIA-AA. Results: Correlational and group analysis showed a positive association between oxidative stress and neuronal damage. …”
Get full text

Bio-impedancemetry an essential tool in the obesity screening of patients with chronic renal failure [La bio-impédancemétrie un outil indispensable dans le dépistage de l’obésité c... by Samia BOUDANI, Faiza ZERDOUMI, Naouel FZ. BOUMANSOUR, Abbou KADDOUS, Bachir M. GUELLIL

“…The survival of patients with chronic kidney disease (CKD) depends on several factors, abnormal nutritional status such as obesity or protein-energy malnutrition are among these factors. …”
Get full text

A Study on the Genotype × Environment Interaction in Promising Advanced Genotypes of Soybean using Graphical GGE-biplot Analysis by Bahram Masoudi, Amir Gholizadeh, Parastoo Majidian, Ebrahim Hezarjaribi, Nasrin Razmi, Farnaz Shariati

“…As an annual, self-pollinating, diploid plant belonging to the Leguminosae pea family, soybean falls into the most important oil plants in the world, containing 18-22% oil and 40-50% protein, depending on the genotype and environmental factors. …”
Get full text

The application of Information-Motivation-Behavioral Skills model-based whole-course nutritional management in elderly patients with esophageal cancer (基于信息-动机-行为技巧模型的全程化营养管理在老年食管癌... by TANG Ping (汤平), SUN Yun (孙云), WANG Lan (王兰)

“…Results After intervention, the nutrition monitoring indexes (albumin, hemoglobin, retinol binding protein and BMI) in the experimental group were higher than those in the control group 7 days after operation and 1 month after discharge form hospital, with significant difference (P＜0. 05). …”
Get full text

Presenting the local model of increasing the market share in Iran's dairy industry with a qualitative approach by leila taheri fard, farzad asayesh, alireza rousta

“…Milk and its products are of special importance in human life due to their extraordinary nutritional value, and they always provide part of the body's needs in the human food pyramid, including protein and some vitamins and especially calcium, but they do not have substitute products; therefore, in terms of examining alternative goods, the circle of investigation should be limited to all types of dairy products (Mousavinejad & Khoramnia, 2021). …”
Get full text